Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
CDK1 SFN â—¼   COLOCALIZATION 2.0 0.8 intact 5211905 10524633
YWHAB CHEK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20639859 8010047
CUL1 CHEK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17290223 5219620
DDB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
E2F1 CUX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18347061
E2F1 HMGA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22389255
E2F1 DAPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18521079
E2F1 CD2AP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22880102
E2F1 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24076372 18439978
E2F1 DAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18521079
E2F1 HSPA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18840615
E2F1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15271987 18319725
E2F1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15033491
HIF1A EGLN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
EGLN3 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 RCC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP1CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MPRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ECT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RACGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SMARCA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
VAV1 GRB2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HSPA8 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SFN MPRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
MPRIP YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MPRIP YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MPRIP YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRC1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000110 19468300
RACGAP1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19468302 1000111
STAT3 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22108192
RACGAP1 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000110 19468300
INCENP PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19228686
SHCBP1 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN RACGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SMARCA5 CENPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19410539 19398759
IL6 STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8662591 8662795
STAT3 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393476
HSPA5 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CBX8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18927235 0805317105
CBX8 BMI1 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
CBX8 RNF2 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
RHOA VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
VAV1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
VAV1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9799234 8990121
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
RACGAP1 AURKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
HIF1A RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19132225 20001745
RACGAP1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB KIF23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RACGAP1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15190208
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
KLF12 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RACGAP1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SHCBP1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG ERC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
KIF23 ECT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000110 19468300
TRAF3IP3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2CA RACGAP1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 SRRT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RAB11FIP3 RACGAP1 â—¼   COLOCALIZATION 2.0 0.8 intact 18511905 6799554
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RACGAP1 RAB11FIP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511905 6799554
RACGAP1 PRSS23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
AURKB CENPA â—¼   PHOSPHORYLATION 0.8 0.8 Signor 11756469
YWHAQ MPRIP â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
YWHAG RACGAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
BRCA1 KIF23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
CBX8 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24981860
CUL1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22474075
RAC1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
CUL4A WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
CENPA CENPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16622419 15009096
CENPO CENPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 16622420
CENPU CENPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16622419 26496610
BIRC5 MED21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAC1 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BMI1 SRRT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26468281 34316702
KIF23 CD2AP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
CENPA CENPI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 15009096
CENPA CENPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16622419 15009096
CENPA CENPB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16622419 15009096
CENPU CENPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CENPM CENPO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16622419 26496610
CENPO CENPI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 16622420
CDC42 RACGAP1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PLK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25483079 24067368 31730000 29656893
CBX3 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 33022573 27705803
CDK1 CDK3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CDK1 BIRC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11861764 17681274
CDK3 AKT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
WDR5 DDB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31155351 33022573 17041588
RING1 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 33022573 27705803
CENPH CENPK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 16622420 33961781 24981860
CENPH CENPU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 21454580 33961781 24981860 16622419
RCC2 RAC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25074804 12919680
RHOC RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781 31980649
KIF23 ECT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22750944 19468300 31586073
CENPA CENPU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 16622419 21454580
CENPO CENPU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 16622420 33961781 26186194 16622419
CENPU CENPM â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16622419 26496610 24981860
CENPU CENPI â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 24981860 33961781 16622419
CHEK1 CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CDK3 RACGAP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
PLK1 PRC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17351640 19468300 31586073
HIF1A STAT3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
PLK1 MPRIP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
STAT3 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15735682 18985005 23604114 23991099
RAC3 VAV1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
RSF1 SMARCA5 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BYSL RACGAP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
RING1 E2F1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11583618 27705803
RAC1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11021801
RACGAP1 KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8397056 22580824
CHEK1 DDB1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
RAC1 VAV1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RYBP CBX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34316702 27705803 22325352 33961781 24981860
CBX3 RING1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 12004135 24981860
TANK PLK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20484576 33961781 21988832
CENPA SSRP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16622419 34079125
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
YWHAG KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5217174 15324660
CENPA RSF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 24800743 15009096
FZR1 PLK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CENPO CENPU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CENPH CENPU â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CD2AP SH3KBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRCA1 CBX3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 23074186 25634209 25184681
CUL1 E2F1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10559858 11245432
HIF1A EGLN3 â—¼   HYDROXYLATION ✅ 0.88 0.88 mint 5217229 15474027
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RACGAP1 ECT2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 18201571 6166552
IKBKG TANK â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RACGAP1 SHCBP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CENPI CENPU â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CDH1 CTNNA1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CSTF1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29180510 11257228 11278247
CDK1 LATS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9988268 12372621 25218637
MEN1 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 27705803 23508102 24981860 14992727 15199122
RYBP WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 26186194
INCENP BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5219326 17099693
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
KIF23 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CENPA CENPC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 16622419 19503796
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
GRB2 VAV1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11733001 15838516 8846921
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
E2F1 SMARCA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
E2F1 RACGAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21886810 19015243
E2F1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23796898 17360938 16582100
E2F1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18840615
E2F1 ECT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21886810 19015243
E2F1 KIF23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19015243
YWHAQ E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15494392
HIF1A EGLN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 18402654 18063574 16511565 15474027 31239290 24015760 17069766 17353276 16155211 30067985 26972000 23345396 15721254 18264140
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2CA IKBKG â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 506986200 8205130 16129692
MPRIP RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31871319 9199174 14506264
CENPU PLK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19597481 21454580 33961781 21525413 32707033
PLK1 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 18477460 22641346 22365832
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SSRP1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15979198 8774705 24532586
CBX8 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 34316702 20543829 10825164 20601937 19636380 26496610 27705803 22325352 33961781 24981860 17332741 24457600
AURKB BIRC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11516652 31315909 19951914 20430883 21554500 23945651 19357306 29568061 21051298 32738097 18477699 17681274 17099693 19995937 16291752 27332895 12419797 31586073 24571573
PRC1 RAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
PRC1 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
RING1 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9858531 25416956 29402932 19451220 32296183 22493164 22897849 15386022 16751658 20601937 19636380 16359901 34316702 24457600 9199346 27705803 34133714 22325352 33961781 24981860
AKT2 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23092893 22505453
CUX1 KIF23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19015243
PRC1 RHOC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
PCNT HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
CUX1 ECT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21886810 19015243
CUX1 RACGAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21886810 19015243
CBX8 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
BYSL ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ECT2 RACGAP1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CENPH CENPK â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
RING1 CBX8 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
RNF2 CBX8 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 5219708 17332741
EGLN3 HIF1A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
WTAP ZC3H13 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
RING1 RYBP â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
BMI1 CBX8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CD2AP GRB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10339567 19380743 21706016 21988832
CBX8 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219708 17332741
BMI1 CBX8 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 5219708 17332741
RING1 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
RNF2 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16710298 5218667
BMI1 RING1 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7998286 20601937
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CBX8 RNF2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CBX8 RING1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
BYSL FBL â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CBX8 RING1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21282530 25416956 32296183 10825164 20601937 26496610 27705803 24981860
RYBP RING1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16943429 28514442 10369680 16189514 25416956 32296183 34316702 27705803 34133714 22325352 30217970 33961781 26186194 24981860 17070805
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
BMI1 RING1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PPP2CA TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
KIF23 RACGAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 CHEK1 â—¼   REGULATES ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17218262 17303408 17660363 18414028 18590585 7575488
CDK1 BIRC5 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11069302 12124778 12792650 14551205 15279786 15917306 17303408 17466630 17660363 18414028 18590585 19016842 19081073 19586613 19652693 7575488
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
E2F1 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 7623816 14618416 12760745 11799067 8137237 12629169 17108174
CDK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 16565220 24281185 18676872 11149963 12529428 24478433 19287963 18936249 18949405 16170024 20068231 28536639 16189514 33710603 20462440 29371939 18691976 15894279 12517802 11861764 11069302 33211707 28392503 21765467 23433354 18931693 15735703 34034636 25468890 26918045 32373497
CDK1 SAMHD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23602554 23972988 26667483 25847232 24586870 24623419
CDK1 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17145710 12372621 25482410 18691976 25218637 23985307 15688006 9988268
CDK1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20798862 19837665 18691976 21765472 21907702 29092815 18983824 16629900 22686412 24242917
CDK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21189248 16170345 22172673 22898780 18669648 16247472
CDK1 CUX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11584018 17570479
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
CDK1 HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17081983 20068230 17924679 17960875 20068231 2168176 17570479 1939057 19413330 20123066 19664995 18669648 15302935
CDK1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7575488 18590585 17303408 8087847 27175585 17570479 17660363 15279786
CDK1 PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29484112 18691976 22621898 17351640 17438553 17512944 16603632 30992425 20633640 23940115 9885575 16964243 27551054 34158398
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26460953 20427271 25798441 28314740 29971233 19303298 21149564 26528436 20633640 16378098
E2F1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10884389 12496474 15220350 15279786 17218262 17303408 17660363 18590585 18660752 19525936 20376879 7575488
PPP2CA CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11390642 17015476
E2F1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7575488 18590585 20376879 17303408 18660752 19525936 17660363 15220350 15279786
CHEK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18451105 20068082 23844048 12560483 18066052 20948546 21357687 18243098
CHEK1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23321637 22024163 17276342
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
E2F1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23449974 19497660 15271987 16601104 17848598 19102934
HIF1A EGLN3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19828020 15156561 20727020 15823097 22555025
HIF1A EGLN3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17145710 15652751 26972000 15721254 16391536 16511565 24990963 12351678 31515488 24145445 17353276 15474027
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 VAV1 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10077632 10086337 10426994 10567412 10646608 10679059 10714681 10811803 10849438 10898494 10982827 11080163 11447289 11526404 11698448 11754814 11777939 11777960 11907067 11994416 12094222 12165654 12175651 12186560 12616499 12626562 12640133 12740575 12885870 12917349 14764585 15169881 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 8551221 9438848
VAV1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 8900182 10207103 9013873 15558030 7651724 7809090 8621483 29997244 18692475 7478592 16713569 11406576 9209406 16339550
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
TANK IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 19854139 25861989 17468758 20484576 12133833 16189514 21419663
MEN1 CTNNA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
MEN1 CDH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
PLK1 CENPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17188028 20148280 17081991 19597481 21454580 24722413 25658810 18215321 34094674
PLK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17332740 18669648 16247472
PLK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20427271 22560880 24091645 24069188 21148584 25169932
PLK1 RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 28692064 17081983 16565220 27453045 19007248 19468300 25486482 19468302 19690332
SFN YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
RSF1 SMARCA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 18519663 20923775 26666816 12972596
IL6 STAT3 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
STAT3 HIF1A â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19265129 18644974 16007214 20924113 17597020 23991099
STAT3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22927445 22363173 19797626 22547075 18765795 18616672 23954444 20493732 19751774 22105366 10391682 24315995 20930550
STAT3 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19880237 26512963 15184887 15469392 16651438 18242580 16397018 21344490 20826784 24431073 15077160 12393476 19284568 17880940 17533050 17932422 22984561
IL6 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 26291658 30185178 20185553 28222632 11322950 30143645 27074565 28687744 21538419 16278387 28128332 24496235 26166037 21625597 20371721 25750173 29330478 19962667 26010889 24513872 29702530 25881314 24078775 27866206 24619648 27840174 19380824 24661007 11728826 21619877 11056211 17142955 26417930 29270528 18611949 25452693 27795451 16520748 26843613 29807795 21442031 26893580 26061710
RAC1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 26430964 16189514 11021801
STAT3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15735682 18985005 10973499
RHOC PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
RHOA PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
YWHAB PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
VAV1 CDC42 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
VAV1 RHOA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
VAV1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8990121 9601639 32203420 11790798 10727406 18488041 23525006 11287617 10592173 10744696 16397238 18511940
VAV1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 11698448 16189514 10646608 11994416 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 14764585 15169881 26192618 22786724 8226994 12094222 8189062 11287617 16887996 12186560
VAV1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 10592173 11698448 10646608 11994416 16397238 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 32203420 9601639 14764585 15169881 22786724 12094222 26192618 8189062 8226994 16887996 12186560
HIF1A IL6 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10804084 15749903 16110315 16127144 16243976 16413922 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 9743347
HIF1A IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17548584 20003295 21258402 15913932 18791496
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
AURKB RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15630414 14744859 19007248 17178910 19555392 18201571 17287340 12689593 15108802 18669648
AURKB CENPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14667408 18239465 11756469 15108802
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
BIRC5 INCENP â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 INCENP â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
HIF1A BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22925504 16847054 19245702 23732337
CDH1 CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 7542250 19016843 25468996 9326449 16212417 11960376 11801604 8227214 10381631 16219695 9700170 24336504 22750944 9233779 11226248
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
ECT2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 32203420 9113980 9641915 15774750 11149925
ECT2 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15642749 9490022 9113980 10816584 17045588 8836113
BMI1 RNF2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BMI1 RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16710298 22493164 22902369 20068231 22325352 25355358 17157253 16751658 26496610 16714294 26468281 26151332 12183370 12589020 21772249 25843776 20601937 32296183 21676867 27647897 15563468 27705803 16359901 24457600 19636380
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
PPP2CA AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15367694 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523 18160256
PPP2CA RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18201571
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105