Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
VAV1 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
VAV1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF6 TNIK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
PLEKHF2 PRPSAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
E2F4 PRPSAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
VAV1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
VAV1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9799234 8990121
FGR PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9636140 23109003
ABI1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
FYN NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
ABI1 RASA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
RASA1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731661 15504032
NCK1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
NCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
RAC1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
NCK1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
NCK1 DOK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211702 10428862
SH2D3C CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABI1 HCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
FGR ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
PRPSAP1 DDX19B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRPSAP1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ILK PXN â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
CAV2 NCK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 12091389
IVNS1ABP PRPSAP1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
RAC1 VAV1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
SOCS1 NCK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
PRPS1 PRPS2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PRPSAP1 PRPSAP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CAV1 RAC1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
SOCS1 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
HCK RASA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 7782336
RASA1 CAV2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15504032 12091389
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
TNIK NCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17474147 33961781 32640226 10521462
ABI1 NCK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 11557983 11418237
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MAPK1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
HCK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9636140 16809022 23109003
NCK1 RASA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21664272 10508618 16189514 9233798
CAV2 CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12414992 16189514 31980649 9361015 18081315 33961781 24013648 10212252
MAPK7 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10473620
DOK2 RASA1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 10799545 16189514 10822173 10428862 9478921 10508618
RAC1 CAV1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 24625804 27250250 22614015 20460433 31871319 15976327
DOK2 NCK1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 11689432 16189514 10428862
PRPS1 PRPSAP2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PRPS2 PRPSAP2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PRPS1 PRPSAP1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
NCK1 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5220560 7744004
PRPS2 PRPSAP1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
PAK1 NCK1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11278241 10805734 8824201 11157752 10026169 10330411 10372803 33961781 9851874 11557983 15784622
PRPS1 PRPS2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25416956 25910212 26496610 32814053 33961781 26186194 22939629
PAK1 CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9535855 11157984 21029865 16678097 19596003 23455922 9705280 31871319 25150978 12879077 12606577 10360579 31478661 10684602 8107774 21048135 23175184 18057010 10802735 21167153 15548653 12650940 18426980 7744004 20936779 24276241
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
PAK1 RAC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 24625804 19327867 15143066 9535855 17245428 11134022 15673687 15289329 16492808 16551621 21029865 16678097 19596003 26175416 17389360 31871319 24056087 25843002 25150978 12879077 15212766 19693014 11030651 16630611 20810653 8107774 11130076 25468898 29615491 19732720 19270716 21474670 10706722 19277120 10802735 21167153 24172987 21454543 15548653 16002993 12650940 18426980 19961560 11950930 24792722 15688026 7744004 20936779 25819133 15075243 22581261
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
VAV1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 8900182 9013873
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19917258 17855441 21419341 21900237
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
MAPK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10753946 15494312 11784715 14636584
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
NCK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10805734 11278241 10026169 23109003 11096073 10330411 8798379 11278553 16490784 11157752 15784622 9024622 9755165 8824201
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
PAK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26598620 10330411 11096073 16717130 14580336 18986306 27542844 28214467 25472536 17440071 23317503
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
FYN VAV1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 12218089 12731048 15699036 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502 9822663
VAV1 CDC42 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
VAV1 PXN â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
FYN VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11262396 15699036 11005864 9438848 16713569 15933714 9822663
VAV1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8990121 9601639 32203420 11790798 10727406 18488041 23525006 11287617 10592173 10744696 16397238 18511940
VAV1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 11698448 16189514 10646608 11994416 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 14764585 15169881 26192618 22786724 8226994 12094222 8189062 11287617 16887996 12186560
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
PTP4A3 PXN â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 17409395 23691193 24376839 27588115
PTPN12 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9497381 19167335 10625692 11950600 10085298 10400685
FYN PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7617039 10804218 16713569 23128389
MAPK8 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20068231 18713649 12853963 23890137
PXN ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11694518 11304546 10592173 16936772 17553790
NCK1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
PTP4A3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16540666 17192274 17409395 18268019 20681446 22677902 22825514 23691193 24030100 24376839 25687758 27036022 27452906
RASA1 CAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12091389 23331499 15504032
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
RAC1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17251915 12213839 18423204 18426980 10592173 22252525 10930450
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
CDC42 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 12213839 25284480 18426980 10930450
PRKCA ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22521536 17570479 17420447
PRKCA PTPN12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19651622 18767875 7909431 20068231 7520867 94349924 15212693 18669648
PRKCA PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15212693 18337243 11741879 11948398 17570479 34010649 10197446 10867018 15024053 15383279
MAPK8 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 9020136