CCT2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MYC
|
CCT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11983916
|
CCT5
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CCT5
|
IKBKE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SEC24A
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790530
2391366
|
SEC24D
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790530
2391366
|
SEC24B
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790530
2391366
|
CD74
|
SEC24C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790530
2391366
|
SKP1
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791267
10023660
|
FZR1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791267
10023660
|
HSPA8
|
IKBKE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MYC
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15466196
12080469
|
PRKDC
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PRKDC
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP6C
|
SEC24C
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21532587
23864707
|
HTT
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NFKB2
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10595582
17855547
|
TNF
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21887257
19287455
|
TUBB6
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TUBB6
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
LRRK2
|
DYRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
HSPA8
|
PRKAA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
26902588
25961502
|
HSPA8
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
BTRC
|
SKP1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
SKP1
|
NFKB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14743216
|
HTT
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DLD
|
BCKDHA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2188967
10745006
|
DLD
|
BCKDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2188967
10745006
|
CHUK
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
CHUK
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
NFKBIE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
14743216
|
RELA
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211837
10498867
|
BTRC
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
9990853
|
SP1
|
ILK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19176380
24361375
|
SP1
|
NFKB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7541912
|
BTRC
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
ARHGEF2
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
VAC14
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BCKDHB
|
BCKDHA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12902323
5216602
|
DBT
|
BCKDHA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2188967
10745006
|
DBT
|
BCKDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2188967
10745006
|
PPP6C
|
SEC24A
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21532587
23864707
|
PPP6R2
|
PPP6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8208117
16769727
|
PPP6R1
|
PPP6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8208117
16769727
|
PPP6C
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP6C
|
SEC24D
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21532587
23864707
|
PPP6C
|
SEC24B
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
21532587
23864707
|
HSPA8
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA8
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA8
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NFKBIE
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
REL
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP6R2
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP6R1
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ANKRD28
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PPP6R3
|
NFKBIE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NFKBIE
|
PPP6R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8208117
16769727
|
LRRK2
|
ABCE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
MYC
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
RIPK4
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29435596
26972000
|
RIPK4
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29435596
26972000
|
LRRK2
|
RHOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
21454543
|
ESR2
|
NFKB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29509190
25604459
|
VAC14
|
MAVS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PLK1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25483079
24067368
31730000
29656893
|
LRRK2
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19826009
31046837
17400507
|
AURKA
|
REL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MOB1B
|
MOB1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
24366813
33961781
|
ANKRD28
|
ANKRD44
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
PPP4C
|
TIPRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
PRKDC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10608806
25223785
|
IRAK1
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
CCT7
|
IGBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
CHUK
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
10521409
|
AURKA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22110403
14990569
26831064
|
IKBKE
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
ANKRD44
|
PPP6R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
SP1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
14710355
16713569
12706836
10720440
17766039
|
FZR1
|
PLK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IKBKE
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
SEC24C
|
SEC24D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
RELA
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BTRC
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CHUK
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
MYC
|
PLK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27773673
17314511
33494392
29467282
30415952
|
ILK
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32707033
23455922
25852190
|
IRAK1
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
NFKBIE
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
11274368
18003922
17418410
15780936
32115405
|
MYC
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12963825
21988832
17314511
29467282
30415952
|
AURKA
|
PLK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22939629
18615013
18773538
|
PLK1
|
MAVS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
30267576
32877691
33961781
|
TAB2
|
IRAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24735611
23986494
19675569
18180283
11518704
12242293
|
HSPA8
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
MAVS
|
DDX58
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22114345
20007272
32612200
31433974
20071582
22022264
19164550
30193849
30267576
21903422
33649232
20554965
16153868
20080758
21102435
21292167
29053956
26494172
26061460
33372174
28594325
21844353
30558248
16127453
18200010
16177806
22301138
17190814
29263274
24478431
20434986
22623778
16585524
19193793
34544279
17709747
19454348
20406818
33976430
|
ANKRD44
|
PPP6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
REL
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
NFKB2
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
SEC24A
|
SEC24D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
IGBP1
|
TIPRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
MYC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12646176
11916966
16713569
20215511
9788437
30415952
14612409
|
MYC
|
CCT5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
SP1
|
CD74
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8955189
10567217
17511886
|
RELA
|
CD74
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8164652
|
REL
|
CD74
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8164652
|
MYC
|
HSPA8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11983916
12695333
|
MYC
|
ELK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
PRKDC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
CUL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10970882
12835716
|
MYC
|
RHOA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22159222
20383141
22235332
|
RELA
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12027803
16713569
|
MYC
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16376880
16915296
|
MYC
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11274368
16713569
|
ELK1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10913190
19687146
11520792
|
PPP6C
|
MAP3K7
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
608155200
17079228
8204431
|
SP1
|
HTT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22399227
20018729
|
NFKB2
|
REL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
14743216
27609421
17962807
8413211
8152812
33961781
26186194
|
SEC24A
|
SEC24C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
IGBP1
|
PPP4C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
NFKB2
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
DBT
|
DLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
IGBP1
|
TIPRL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
23892082
26344197
|
CUL1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
17318178
5219675
|
CHUK
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.93
|
STRING
|
36370105
|
PPP4C
|
IGBP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
27880917
|
SKP1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
7304783
18818696
|
SKP1
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
9660940
6547997
|
PPP6C
|
PPP6R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
PPP6C
|
PPP6R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
PPP6C
|
PPP6R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
DDX58
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
BCKDHA
|
BCKDHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
IGBP1
|
PPP6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
MAP3K7
|
TAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
BTRC
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT7
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
BRCA1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
BRCA1
|
AURKA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
SP1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15252835
17373631
18377656
19466541
|
MYC
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12032322
19882681
20940401
10375022
21668996
11916966
12646176
11983916
|
AURKA
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
22864622
22340593
18026198
24775809
14990569
|
TNF
|
CD74
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
MAVS
|
IKBKE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
17145710
15210743
16127453
19153231
17020950
25636800
15210742
16306936
12702806
16177806
27419230
36056146
19546225
19380491
16858409
21200404
24706939
18207245
17468758
17327220
|
DDX58
|
IKBKE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16177806
17020950
15210742
15210743
23950712
16306936
16127453
17468758
12702806
17327220
16858409
16281057
|
IKBKE
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
28317833
12842894
16046471
20188669
15128824
17561400
17003035
30223576
15485852
10521409
15489227
15849198
16407239
26025205
15212693
12767944
|
PLK1
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11073952
17596790
18931676
19270156
19622404
19686080
8127874
|
RELA
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12894581
18184402
7869034
17673602
12783888
11114727
17944672
9596659
19469019
21790895
19766095
17018379
8289784
18566231
|
SP1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11470523
9492315
2284094
8437848
7753559
8355712
2057364
|
MYC
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20890087
20519624
14744757
20682043
|
PLK1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18931676
19270156
25915540
23887393
19622404
19686080
|
CHUK
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
AURKA
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
18566290
23618492
27721411
24338364
15713655
28126323
34260926
19364923
33805672
33771996
32284347
27504491
33898950
10980711
26206521
21474997
32060423
27662907
28994651
33963314
18615013
23695676
34197606
18669648
25925375
26114094
19228686
28591578
22281053
18691976
20603326
15611664
27068477
27908669
26919439
26012549
18477460
34140642
25660017
27899378
19369195
21454580
25871386
24349352
12207013
20869364
11854496
20633640
28351953
24667170
25042804
|
TNF
|
TAB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
REL
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10201927
17513725
18990758
16997280
7624137
23195252
17012234
11350953
17082635
|
SP1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
23733894
12759366
27030318
22534375
7649977
12509451
12378384
15175554
18357389
10829018
11390427
17897957
18218727
8258705
12560487
17047073
21320120
7918637
16847329
10559188
18930140
20068037
1618817
21784970
10688670
10913190
17307735
18467438
21411747
11500175
20221720
20701940
|
RELA
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
136.0
|
1.0
|
Omnipath
|
26596471
17707233
20817730
12686724
27075886
21765477
21537341
19530226
17390058
18077329
15064230
20617556
8805669
17351769
23335080
21573233
17292554
16285952
9916895
11749970
7895918
17496784
12628924
23857586
12657243
15857826
12471036
11259437
16433741
9831247
20237317
15465827
26023919
22661093
10748079
15013838
17350185
10754326
15470505
11827962
20139176
26408955
22901690
18772140
21108432
22742857
23195252
18362169
24012417
11312646
17442180
9281604
10079106
11297551
15081318
22718766
24908318
8219230
26004152
11094063
11490006
9916692
16483936
18057724
16569682
22138107
18467438
20547752
22723832
19846753
17407192
20221401
19854828
20534538
7876168
16707469
12117498
20544543
23178569
15812247
21138578
12610112
25888873
16916598
16040075
28039105
14749357
20066113
19285436
25161822
22388040
14960579
20195282
16199883
15543947
23971673
10551799
11290773
22798670
22021035
20722069
20221720
27338466
19385047
12058956
26997758
25690886
7624137
20686703
26114754
14976218
10485496
17607667
8622636
11007957
18285351
10837498
11739517
18719026
17268554
17085785
17142966
10963848
9742085
23042817
27534992
10553096
26516703
20696864
10201927
16850160
8679226
21098092
20097764
9129150
17082635
|
TNF
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
15192014
27329558
22240205
15833743
19351843
28187781
15841081
28107185
28373828
26999213
24386331
24957606
26179215
21572963
18258304
28317833
29441018
10722927
19596989
28423685
12881425
25118327
24036851
28089769
21904602
24141032
10938077
30201812
20691659
24166907
19789307
19393267
22768286
26310932
19411070
23789107
28790310
29708974
20507904
|
MAP3K7
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
TAB2
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
TAB2
|
MAP3K7
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
CHUK
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
20300203
9744859
17047224
11460167
17496917
14514672
|
IRAK1
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12242293
17197697
|
PPP6C
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17079228
|
TAB2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
112.0
|
1.0
|
Omnipath
|
17145710
11477091
17301840
18180283
10838074
24912525
16251197
10882101
19556242
15125833
19955178
31250519
36130827
17363905
17158449
11259596
19026643
24699077
14670075
18641653
24061540
24403530
23331499
22158122
12372426
21903422
27426733
21071413
23180781
14743216
18021073
21133840
20200282
26432169
21232017
18264787
20194509
10391247
18988627
22081109
8638164
16799562
11809792
19232515
12620219
14633987
19161412
20538596
22941947
23681101
20932475
15590691
12609980
16845370
27468689
12242293
11280761
15082531
26192618
14660645
24958845
17172402
15327770
25642820
22167179
20164171
16603398
17384642
11460167
21041997
|
MAP3K7
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
14960582
16893890
15836773
33895773
12547194
25241761
24911653
2547194
9742107
18949366
11274345
20200282
20194509
10094049
18855897
10187861
|
IRAK1
|
TAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11518704
12242293
19675569
23331499
18180283
21071413
11259596
|
TAB2
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14960582
15836773
11274345
20194509
18855897
|
NFKBIE
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
REL
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
RELA
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9990852
10514433
9859996
9990853
7628694
|
NFKB2
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9346238
15340381
16303288
8706131
|
CUL1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15668399
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
CUL1
|
SKP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
14685242
16189514
17290223
20832730
12504025
12904573
10230407
19933270
23324393
12504026
9636170
26540345
12609982
27697867
26753747
21145461
22474075
28007894
18818696
9736735
9990852
22767593
28152074
10023660
29070679
9827542
23951410
16357137
16759355
10713156
15452136
19270694
11027288
26474281
23770852
10648623
29499133
21249194
34499862
12628165
15966899
21169563
22660580
11961546
9430629
32313199
29863914
10230406
30653357
19945379
9663463
21778237
34237211
18094045
26976582
27705803
32249768
29103612
33961781
12684064
26725323
|
CUL1
|
SKP1
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
14536078
15071497
15147722
15340381
15459660
15489953
15668399
15688063
15703371
16697054
17053147
17884153
18636226
18787170
18931676
19150432
19270156
19622404
19686080
19797085
19809470
19847258
|
SKP1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
9663463
19945379
12684064
19270694
16759355
23951410
10648623
11961546
26540345
26976582
26474281
17290223
9736735
21169563
14685242
16357137
21145461
29070679
15452136
15966899
12628165
21778237
22474075
16189514
22767593
11359933
9430629
10713156
10023660
10228155
12504026
18818696
9827542
12504025
18094045
10066435
23324393
23770852
9990852
12417738
27705803
9636170
21249194
12904573
34499862
11027288
26725323
20832730
19933270
12609982
10230407
|
NFKBIE
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
BTRC
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CHUK
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9346238
15340381
16303288
8706131
|
SKP1
|
NFKB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9346238
15340381
16303288
8706131
|
SKP1
|
REL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
SKP1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9990852
10514433
9859996
9990853
7628694
|
CHUK
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9346238
15340381
16303288
8706131
|
NFKBIE
|
CHUK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CHUK
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CHUK
|
REL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
CHUK
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17145710
15611276
22110409
19609947
10521409
20863851
20051109
20363318
12767944
26999213
12842894
21903422
19110719
15858576
16382138
22155370
23894194
16046471
15128824
21569639
16846590
8246997
15485852
25341660
15494311
11983155
15980040
15489227
15849198
14636585
23343355
|
CHUK
|
NFKB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
17145710
16970925
11520989
15310758
16793322
28829404
12387745
26999213
18617892
14743216
15218526
15140882
15214841
17561400
15084608
15371334
16285893
22388891
15145317
29907126
26462035
11239468
17072322
|
RELA
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9990852
10514433
9859996
9990853
7628694
|
SP1
|
RELA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7636984
8450395
9151857
20538607
11964305
|
RELA
|
NFKB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9056676
9528780
15755876
7541912
|
PPP4C
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15073167
9837938
16189514
|
RELA
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12055073
7933095
10671503
20861353
|
ARHGEF2
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9789025
22072711
32203420
9113980
9641915
10592173
9857026
20810787
16189514
24525234
11149925
|
NFKBIE
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
REL
|
BTRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10321728
9990852
10066435
9859996
10514424
10230406
|
BTRC
|
NFKB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
11994270
18617892
14743216
16303288
|
DDX58
|
MAVS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
17145710
20554965
16127453
33372174
20007272
35075101
21419663
16585524
20406818
19052324
17020950
21903422
19164550
24478431
17190814
16713980
18200010
18948594
19193793
16177806
34544279
16153868
23843640
16785313
16301520
21844353
16125763
19036819
18977754
21102435
33976430
22301138
17709747
21200404
29263274
26494172
23499489
18207245
19881509
22844514
20080758
|