Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AURKA CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
CHAF1A CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CKS1B CDK2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
HIF1AN EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12573436
FOXO4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19560465 17242183
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 EIF3D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NFKB2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10595582 17855547
USP7 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HIP1 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOCS3 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16568091 22547065
AR SAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20460526 20610535
TTC19 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
NFE2L2 OSGIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18535259
RELB NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CREBBP RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12789342
FOXP3 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23201402 20554955
SP1 FHL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16624878 0602109103
SP1 ELF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212972 10976766
SP1 GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12972613 22265959
SP1 SRF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10602487 10330138
SP1 NFKB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7541912
MTPN HIF1AN â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 17003112 0606877103
ATXN1 PSMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 17975004
FHL2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TLE5 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBP MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 19620725
TBK1 REL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888014
EIF5A2 DHPS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CPNE2 HIP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CPNE2 EIF3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
REL RELB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27609421 33961781 26186194
AURKA REL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
REL TSR3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TBP REL â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8413269 16713569
REL EGLN3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25416956 26972000
DMRT3 TTC19 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
DMRT3 SAT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
IKBKE TNF â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
POLR2L TBP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
REL RELB â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP GTF2B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
CINP CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16082200 19889979
CDK2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11598016 19450264
CREBBP FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15126506 10973497
NFE2L2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17313370 18241676 18199529
RELB NFKB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 27609421 17962807 22864569 33961781 14678988 12505990 22388891
SP1 PTK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11997104
SP1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14561739 16452190 9295358
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
NFKB2 REL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 27609421 17962807 8413211 8152812 33961781 26186194
EXOSC1 EXOSC8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
GTF2B POLR2L â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
DHPS EIF5A2 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
DHPS EIF5A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
NFKB2 REL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EIF4E2 EIF4EBP1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
DHPS EIF5A â—¼   POST_TRANSLATIONAL_MODIFICATION ✅ + 0.93 0.93 Signor 32142284
CKS1B CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 8601310 5220942
EXOSC5 EXOSC8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
EXOSC1 EXOSC5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
EXOSC5 EXOSC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24981860
EIF3A EIF3D â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 18599441 9822659 22939629 17353931 22190034 22863883 33961781 24981860 23623729 9341143 14519125 26344197
NFKB2 RELB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK2 CKS1B â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GTF2B TBP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3A EIF3D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MAPK8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18594987 25326334 25077544 27374471
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
MAPK8 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11689711 20959475 17570479 15538382 15212693
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
NKRF NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10562553
NKRF REL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10562553
TNF FOXP3 â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 11112697 12646658 1431106 14607933 14625680 15099563 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 8910423
REL TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10201927 17513725 18990758 16997280 7624137 23195252 17012234 11350953 17082635
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
RELB TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21245135 10523657 16997280 7624137 19158276 20686703 9164938 17646159 21562054 15470505 17082635
SP1 CDKN2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18642058 15107822 22504641 12077144
NFE2L2 SAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12020345 10419538 9852135 12804587 11256947 16647090 23943804
MAPK8 BMF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18222916 12591950
NFE2L2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24466341 17640564 18588981 15655294 22951256
CREBBP NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21196497 11683914 11154691
NFKB2 RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17145710 20126461 16551621 17072323 16970925 16793322 12709443 11687592 9681829 17962807 14743216 17254973 15218526 7925301 16108830 12927781 17561400 15371334 16285893 15145317 19098713 12505990 17548614 17072322
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7553870 9060426 2674689 24669866
SP1 ALOX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16413224 2251250 9698605 17894944 23720274 20554538 19781662 9062372 16364163 10436859
SP1 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15708372 9154804 14726517 15661808 23662037
MAPK8 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28831131 22266860 18199680 19245816 25398907 17570479
AURKA NEDD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20825672 23539442 16184168 19937461 25817040 19539609
TBP HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8648740 9199313 16330756 8218418
AR NME7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
FHL2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17192406 10654935 16713569
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
EIF4EBP1 EIF4E2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 28698298 17145710 17368478 15094042
TBP GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7666533 8670811 11971135 8946917 9121468 9407004 7706261 16330756 7823952 7609077 8051080 8087622
DHPS EIF5A2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 7673224 16452303 14622290 9188485
DHPS EIF5A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 7673224 16452303 14622290 9188485
DHPS EIF5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 32142284 25416956 12788913 16189514 32296183 12562768 7929297 10229683
REL BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12414938 23271966 11880364
SRF FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22456196 15610731 17975004