Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SLC16A1 CEP43 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NEFL SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16227626 9806359
TP53 ANTXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11711532
ATF4 S100P â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19073601
S100P CACYBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12042313 16189514
CYB5R3 CEP170 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16293792 22890843
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
CREB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16862174
CREB1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
HTT CSF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 CTSL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 20536385
DDAH2 TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD3 EBI3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14741200
WFS1 EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERBB3 FER â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 S100B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT EZR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FXR2 GPSM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TP53 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23940366 9360971
GPSM1 TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HIST1H3A SPIN1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HMGA1 LEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259597 19633359
SNW1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PFN2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PACS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MKNK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDUFB9 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMA6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17564708 24180280
IL24 IFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18511292
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
TP53 MYO6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16507995 20576604
TP53 PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22266808 15829976
PEG10 ZNF512B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRPH SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
S100P S100A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
S100B S100A1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
WFS1 S100P â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNW1 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213835 11278756
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
STUB1 SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 21454478
WFS1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TP53 TFDP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
WDR26 YPEL5 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CRTAP PLOD1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SNW1 TFIP11 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
TP53 HSPA9 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5219502 17184779
NUSAP S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CC103 S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TB22B S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGR2 S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31436131 30575818
ARC FER â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BICD1 BICD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28718761
HTRA4 WDR26 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZIC1 S100P â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SRPRB UBL4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 23246001
YPEL5 WDR26 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 29911972
HIST1H3A SP100 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PIP5K1A PIP5K1C â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST1H3A MORC3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
TP53 FBN2 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
SNW1 SPECC1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
RAGE S10A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17726019 11007787
CYBP S100P â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31837246 16189514 12042313
S100B TP53 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
S100P TGFBI â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
FAM126A TTC7B â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
RPS6KA1 S100B â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CAPZA1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EZR MSN â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
S100P RAGE â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16061848 14617629
SGTB UBL4A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 26496610
CRTAP LEPRE1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
ZNF629 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
RFWD2 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ARC CSRP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HSPA9 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ARC S100P â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
S100P EZRI â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 12808036
MYH9 S100P â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31837246 15171681
S100Z S100P â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 11747429
AGR2 SGTB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
SMAD3 SNW1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11278756 18729074
AGER S100P â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
METAP1 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
S100B S10A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27107012 32296183 9925766 32814053 26871637 21516116 26264872 25416956 16189514 29997244 10913138
S10A1 S100P â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27107012 32296183 15171681 25416956 16189514
RAGE S100B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21693575 10399917 17726019 17660747
CREB1 S100P â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20890108 20155429 18636203
CREB1 LEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20484458 18787032 23056265
RPS6KA1 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 MKNK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IL12A EBI3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22487722 18033300 9342359
SMAD3 IL9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26365427 22503540 23913959
TP53 TCEAL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20421190 16061257
S100P UBL4A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
S100B S100P â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
S100P S100Z â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CRTAP LEPRE1 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
S100B S100Z â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
H2AFX TP53BP1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
S100A1 S100Z â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CAPZA1 S100B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
S100A1 S100P â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
S100A1 S100B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
AGER S100B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
H2AFX HIST1H3A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
S100B S100A1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8153045 21516116
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PSMA6 PSMA7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
CAPZA1 BICD1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
MAPK3 CALD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 1601129 11983427 10751321 10514499
CREB1 IL10 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
CREB1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CREB1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22140263 26408955 21986577 19564345 12493739 22116830 10540320 18263767 17202341
RPS6KA1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 11175347 12356771 15733869 11160957 11544482 15138267 11532940 9829964 7958915 10558990 12235136 11335727 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11909979
MAPKAPK2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 11175347 17389598 10679065 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 20626350 11909979 8688081
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
FER PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9786960 15226396 11106648 12377785
HMGA1 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8986808 8934574 1330326 8374955 7972056
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
IL15 SMAD3 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
MAPK3 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK3 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 10197981 15241418 24080014 18775330 8226933 16156666 9604935 12193595 8388392
MAPK3 MKNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 15547943 20080742 12040186 15173823 12697810 11940578 23331499 16227978 8226933 9155017 12738796 16039586 17255949 15187187 19541618 19091303 19565474 17052211 10022874 8388392 18039929 9155018 18775330 9604935 10601235 12792650 11431469
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21675959 17242355 7592979 14499342 14967450 23583303
TP53 S100B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20587415 21546003 15178678
TP53 S100B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20591429 11527429 16713569 10876243 31837246
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
TP53 EPS8L2 â—¼   KO_DOWN_REGULATES ✅ - -1.97 1.96 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368