Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CLOCK SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20868778 22832921
HGS UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
PRKCB MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
MAPK3 IRS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
PRKCB MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
SCNN1G NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11359767 5214035
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
PIK3R1 GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 GABRA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 INSR â—¼   PROXIMITY 2.0 0.8 intact 6731120 10500481
AR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12933816
USP8 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN IRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SP3 SGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9415398 10614661
SP1 SGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9415398 10614661
INS SGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28106162 22842983
TNF PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22078880 20651683
PRKCA ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17570479 14976217
SP1 SLC3A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17023546
NR1I2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
PDPK1 PRKCB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PDPK1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
SP1 SLC7A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17023546
SP1 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887648 19994725
SP1 ATP1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 15462673
SP1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12105191 20179320
SP1 HTR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8626793
SP3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12637574 12888570
INS IRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9609109 15316008
AR IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18521741 20610535
IGF1 INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23518924 32196115
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
AR INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 20417685
NR3C2 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8675013 12767279
INSR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12456798
INSR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8567177 8385099
STAT5A INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11415999 10373481
PRKACA AQP2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12194985 9227644
PRKACA GABBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11976702
PRKACA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8657310 9660757
PRKACB AQP2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12194985 9227644
PRKACG AQP2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12194985 9227644
PIK3CD PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CA PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
NCOA1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16186500 14551261
NCOA1 SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17105732 20054001
PIK3CD PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
AR KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8423674 24172884
AR PIK3CB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23365759 20610535
AR SCNN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17721441
PLCB2 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GABBR2 GABBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218685 16724110
SP3 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11578973 20462637
SP3 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10811658 24219545
PLCB4 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB3 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PKD2L1 PKD1L3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6743415 18535624
PLCB3 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PPARG SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18509005 24735796 20360975 22282354 18310298
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
PDE1C PDE1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PDE1C PDE1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
SLC3A1 SLC7A9 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PIK3CA IRS1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591642
INSR IGF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26027733 8452530
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R2 PIK3R3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R1 PIK3R2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HGS NEDD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 12230472 23602387 25588945 20675381
NCOA1 NR3C2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NEDD4L SGK1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SGK1 NEDD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19953087 11696533 12729930 20730100
PDPK1 SGK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17916563 16189514 10191262 17314099 10357815 12387817
SP1 SMAD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10878024 18215124 21297662 16714330 11114293 22033265
INS INSR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 2550426 11278498 29512653 23302862
NEDD4L SCNN1A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
IRS1 PIK3R2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
NEDD4 SCNN1G â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
INSR PIK3R1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR NCOA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
NEDD4 SCNN1A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CLOCK NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21164265
SGK1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19447520
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
MAPK1 SCNN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11805112
MAPK1 ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15069082 14976217
MAPK1 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MAPK3 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MAPK3 SCNN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11805112
MAPK3 SCNN1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11805112
AR PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22740037 12063252 20610535
SP1 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16814105 19464346 17376651
SGK1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23650397
PPARG TNF â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 10432118 17681149 23390297
NR3C1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15956716 15289446 16557033
SP1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21421563
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
PPARG NCOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23178929 17704298 10944516 15604093 19596656 17312272 10731636 16373399 30595551 17011503 17468099 22070604 15026545 10339548 10347167 9121466 9041124 23975195 20717101 10848596 9744270 17449869 11500849 16713569 11027271 11877444 15888456 17513608 30813326
PPARG IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18394717 20064783 20685873
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
PDPK1 PRKCG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15209375 17053865
SP1 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10558886 10471823 11802722
SP1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12039077 14962081 15249123
SP1 SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12684058 23804453 23926181
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
NR3C1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18174358 24500711 27371733
SP3 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799440 10471823 11802722
SP3 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9415398 11578973 11562358
PRKACA CACNA1H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19131331
PRKACA GABRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1321150 1323140 2176510
NR1I2 NCOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15331348 16455805 17429319 23160820 18096694 15604093 19171678 23602807 12909012 12072427
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
AR SCN9A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 24493753
AR FGF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8580999 20610535 7522959
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
PIK3R2 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402981 8596638 11733063
NR1I2 SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
SP3 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19197985 19011236 19994725
NR3C1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 8878484 9528750
NR1I2 GRM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
NR1I2 KCNK5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
NR3C2 HTR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9191104 9284345 11278286
PDPK1 SGK1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
NEDD4L SCNN1B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
IRS1 PIK3R3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
INSR IRS1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 7651388
PIK3R1 IRS1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 6731578 14632132
IRS1 PIK3CA â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
INSR IRS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
PIK3CB PIK3R2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PIK3CA PIK3R3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
IGF1 INSR â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PIK3CB PIK3R1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SCNN1B SCNN1G â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
NEDD4 SCNN1B â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
INS INSR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SCNN1A SCNN1B â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SCNN1A SCNN1G â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SLC3A2 SLC7A5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NCOA1 NR3C1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR1I2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PIK3CD PIK3R1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PIK3CA PIK3R2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
INSR IRS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11781100 25667086 16582879 17167487 7935368 10455177 11606564 7499194 15629149 8662806 8626379
GABBR1 GABBR2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GNB3 GNG13 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
IRS1 PIK3R1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9804779 25241761 18775330 10194762 8226933 10996427 9604935 8388392 12091337
MAPK1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12351702 18669648 9199329
MAPK1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 25409419 11733495 16574647 9099735 9030579 15507114 26670611 17570479 17998334 18596912
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12801888
MAPK1 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10660621 12163482 11073973 20068231
MAPK1 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11287604 11481231
MAPK1 SCNN1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11805112
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
MAPK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 15001544 17081983 18949383 16123357 27014871 16914728 17360977 16099428 30401435 16131083 17640984 12510059 15613682 21850561 14579029 20594869 8626671 9395471 19651622 15576463 22289259 14769130 16020478 17242212
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9804779 20508164 23331499 24263804 18775330 10194762 12407017 8226933 17502367 34188118 9604935 18988627 31932645 8388392 12091337
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11287604 11481231
MAPK3 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12163482 11073973
MAPK3 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15001544 16131083 8626671 14769130 9335553 15613682 12510059 15212693 9395471 14579029
MAPK3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28115363 12801888
MAPK3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18596912 11733495
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
KRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
INSR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 15629149 17389395 8276809 18083107 11796522 8385099 20068231 8567177 16497976 15592455 17570479 9593725 7589433 14729945 17016520 10500481
IRS1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 12444011 11788580 14632132 14511371 19030972 16931767 7486683 21798082 11403293 12173038 8382612 12220227 12767520 10826997 16230374 7680095 23439647 19561084 16150444 12107746 10358772 11748924 12175651 7499365 7935461 15316008 9564850 16354680 16043515 12730242 11416002 7680644 23643389 21540285 8628286 15514089 11438664 8175658 9233603 1381348 25814554
PIK3R1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8596638 25241761 20713702 27107012 11733063 21825134 32814053 26496610 8139559 14729945 10358930 14665640
PIK3R1 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9113989 8596638 21827948 12147247 11733063 22020336 24165795 31031754 14665640
PDPK1 SGK1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11500365 11687500 11747822 12670391 15802604 16286006 17680028 18802401 19109239 19122654 20932932
NR3C2 SGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16533503 17200434 12969137 24491541 14614041
AR SGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19318566 21809344 20610535 17932503
PDPK1 SGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 16286006 25384981 18802401 12387817 17916563 23331499 11807089 16189514 12023960 10191262 22042038 10357815 24760523 11500365 23317821 20932932 12912918 15209375 24864229 17680028
SGK1 NEDD4L â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 47.0 1.0 Omnipath 20621254 20166139 18767875 23589291 20230923 12911626 11742982 19413330 19664995 15586017 20068231 17570479 16189514 27517916 15140763 18669648 12729930 20730100 18691976 19651622 15328345 22301619 15677482
SGK1 KCNJ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8621594 12878206 12684516 17570479 29352074
SP1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 23733894 12759366 27030318 22534375 7649977 12509451 12378384 15175554 18357389 10829018 11390427 17897957 18218727 8258705 12560487 17047073 21320120 7918637 16847329 10559188 18930140 20068037 1618817 21784970 10688670 10913190 17307735 18467438 21411747 11500175 20221720 20701940
PPARG TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20376096 11009565 14646597 20473515 11124825 17532302 17464333 19031802 14656714
DNMT1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21765477 24875904 23335796 22742857
SP3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14555463 12759366 19109523 11390427 11500175
TNF IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22328823 22869320 19808894 12110133 11160134 12409308 22266116 21478880 11684411 25352752 24966659 29425748 16754954 25355439 22823902 18443205 24648009 26976796 25645159 23592917
TAS1R3 GNG13 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19696921 21422378 19104071 11917125 24214976 15353592 24633359
TAS1R1 GNG13 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19696921 21422378 19104071 11917125 24214976 15353592 24633359
SMAD4 HMGA2 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 9389648
SMAD4 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 HMGA2 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 9389648
SMAD4 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
UBE2I PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19692572 15507114 26192107
PDPK1 KRAS â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PDPK1 PRKCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15209375 17115692 9889098 16189514 11376011
PDPK1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15209375 11078882 10698939 9889098
PDPK1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16026785 20732331 15481030 22493239 10698939 9707564 8706898 20137943 21774789 17192257 22154087 20481595 12372837 16765046
SP1 NFYC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1311316 18310298 7776968 15131018 12706836 12665574 7983788 16707431 22033326
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
SP1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9348238 17446237 23626778 18664368 14744869 15001547 23027183 14998783 17449871 15330762 19485892
SP1 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19145069 11327698 12105191 11578973 12727210 17257588 15533438 18295514 11336542 9756852 17509747 20092859 12694408 19464346 11060301 15380450
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
PRKACA IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17360977 12624099
PRKCA IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22869320 15364919 16574739 17570479 15516986 15069075
INSR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 10655627 7651388 25472611 1385403 18083107 12220227 23331499 28328746 7504175 19534553 7499194 7537849 7935368 11572799 11781100 10592173 17570479 17575262 18988627 12446583 15629149 10455177 15870194 11416002 12101187 17167487 8530377 8626379 8662806 11606564 2159922 8626723 16020478 16582879
IGF1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 26474286 28545881 26956053 25886138 15952059 18762365 22362362 19762915 11160134 22941977
INS IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25309812 25472611 23891856 20150288 29069585 24036112 21518983 11160134 19357636 22198320 17579213 21677282 11684411 23983791 28955049 25760026 21850561 22832498 19808019 22698915 23815272 18443205 20601126 16150913 25383313 27695421 23115649 22728334 19752148 19171749 27819676 16516141 22418434 19542202 25381390 22516431 24763529 26866272 23695665 23431498
IRS1 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16931767 12175651
IRS1 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 11120660 7559478 10358772 16931767 12730242 12175651 7499365 15316008
IRS1 PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 9415396 16931767 12175651 10417350 7542745 25814554
IRS1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16354680 16150444 16931767 10592173 12175651 1380456 23643389 1381348 11313948 9374521 20966354 9624169
IRS1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16931767 14623899 11416002 12175651
STAT5A IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20378540 19920132 17509524 10050749 20372799 21651786 23071812 14532269 15677453 18276757
AR IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24914937 8580999 17363459 22739988
PRKCA INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15212693 2110001 12472845 17570479 8454604 1956339 10819237 7926007 92065884 8463287
PRKCA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9015864 11278470 9349568 2211670 9307019 17570479 21338571
PRKCA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20802526 34333552 23331499 25713064 27791178 18458061 9922370 18182391 16483930
PRKCA GRM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10823959 15305863 17570479
PRKCA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11278298 9660757 15302935 10893237
UBE2I SP3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15494207 12419227 25114211 18617891 18374648 12356736 15247228 16781829
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
CSNK2A1 STX1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15822905 10844023 9930733 19748891 11846792 25774383 18510355
INS INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8393875 21743783 21317886 24296476 26374090 29069585 26245346 16956584 19902173 20332342 23363978 23331499 18988627 23302862 22832498 2550426 15870194 11278498 19752148 29512653 23304064 24633815 17227660 22521887 23223021 30197476
GNB3 TAS1R3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19696921 21422378 19104071 11917125 24214976 15353592 24633359
GNB3 TAS1R1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19696921 21422378 19104071 11917125 24214976 15353592 24633359
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
PRKACA CACNA1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 8664319 8612821 28119464 7621818 9247274 29123182 2174428 10984483 10514522
PRKACA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 28615442 9660757 10893237
PRKACA NEDD4L â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 30453017 15328345 15677482
PIK3R3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8596638 22402981 9415396 11733063 26496610 25814554
NCOA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15514032 12163482 23145053 11673464
AR SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16172422 20610535 17721441
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
NEDD4L SCNN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15586017 15328345 17502380 16844684 18701608 18322022 11244092 14556380 26651153 16416336 18498246
KRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
NR3C1 SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10212217 11266509 10419459 11390395
PIK3R2 KRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NR3C1 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11216640 10329476 9694812
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C2 ATP1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11216640 10329476 9694812
GNAT3 TAS1R3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19696921 21422378 19104071 11917125 24214976 15353592 24633359
GNAT3 TAS1R1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19696921 21422378 19104071 11917125 24214976 15353592 24633359