Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FXR2 SNAP23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIK3CD LYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LYN PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LYN PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LYN ITGB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7219790 14593208
LYN PIK3R5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LYN PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
LYN PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 16713446
F2R MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
SYK MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12038794 8636072
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
F2R MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK3 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15310280 10402467
TGOLN2 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3R1 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
STX4 STXBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15753124 20634814
SNAP23 STXBP4 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15753124 20634814
STX4 STXBP4 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15753124 20634814
SNAP23 STXBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15753124 20634814
SNAP23 TLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212015 10588641
RAP1B TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18434644 17624957
RAP1A TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18434644 17624957
ITGA2 COL1A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219911 17485091
COL1A2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9685391 30632962
NOS3 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
ACTB ITSN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
PRKCA ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590896 10592173
VASP ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 1318192
STX19 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNAP29 VAMP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23466629 23578367
SNAP29 STX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23466629 23578367
SNAP29 STX17 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 23466629 23578367
SNAP29 VAMP8 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 23466629 23578367
VTI1B STX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GNAI3 P2RY12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11196645 8554519
GNAI3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8327893 19703466
ACTG1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 ITSN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
SRC LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10469124 16189514
PIK3CA SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
PIK3CB SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12038794 8636072
SYK PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9720763 10592173
ENG ITGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8410211 22940691
FN1 ITGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
NAPA SNAP23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ABI2 SNAP23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ABI3 SNAP23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNAP23 STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15753124 20634814
SNAP23 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNAP23 STX4 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15753124 20634814
SNAP23 SLC2A4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15753124 20634814
PPP1R12A FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GP6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906436106 19940238
PIK3R2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
FYN PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
FYN TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GNAS ADCY4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
GNAS ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
STIM1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9069260 21779497
STX6 STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
VAMP4 STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NAPA STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VAMP3 STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STX7 STX4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
STX4 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STX4 SLC2A4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15753124 20634814
STX17 VAMP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23466629 23578367
STX17 VAMP8 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 23466629 23578367
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756631 18083107
ROCK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306866
ESR1 ITGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
PIK3CG PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8765021 16527821
MAPK11 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
PRKCA PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16963226
PRKCA VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14706852
PRKG1 ITPR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18757735 0804738105
HSPA5 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STX3 PIK3R6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GNAI2 P2RY12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11196645 8554519
GNAI1 P2RY12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11196645 8554519
F2R GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22318735 31160049
F2RL3 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17158345 31160049
GNAI1 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15922020 19703466
GOSR1 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
YKT6 NAPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
YKT6 NSF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
NSF BET1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
NSF STX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
PRKACA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8657310 9660757
STX5 BET1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15215310 12388752
YKT6 GOSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24119662 19164740
GOSR1 BET1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15215310 12388752
STX6 NAPB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
RAB9A VAMP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
FCGR2A PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PIK3CD PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
PIK3CA GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
PIK3CA PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
GNG3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17419683 16537363
GNAQ PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB2 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PIK3CD PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
ESR1 ITPR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19515975 23884412
PLCB2 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB2 PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PIK3R2 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8596638 11733063
FCGR2A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
VWF GP1BA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215664 12183630
PIK3R2 FCGR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A PLCG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7517665 8657103
PLCB4 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
PLCB3 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
MYL12B MYLK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 3079756 3839510
MYLK MYL12A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 8149717 21457715
ROCK2 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10047526 27037223
MYLK3 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17924679 19690332
VWF GP1BB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
PLCB3 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
VWF GP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
VWF GP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1939645 2010539
STX12 VAMP4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGB â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
F2 FGG â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
STX7 YKT6 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
VAMP2 VAMP3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 12130530
GOSR1 YKT6 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11927603
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
NAPA VTI1A â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
VAMP7 STX8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 19557002
VAMP3 STX8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 19557002
STX11 STX8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX8 STX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
CD81 GNAI3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
CD81 GNA13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
CD81 GNAI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
STX12 BET1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
ESR1 RAP1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
STX4 USE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 32296183
ROCK2 ROCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX6 VAMP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
BET1 VAMP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 29568061
BET1 STX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 29568061
VAMP4 STX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BET1L STX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11927603 12388752
VAMP4 GOSR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GOSR1 BET1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11927603 12388752
STX18 BET1L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAMP7 STX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 19557002
STX11 STX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX6 YKT6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
STX11 VAMP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VAMP4 USE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
YKT6 PTAR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX2 VAMP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12828989 29360461
STX11 YKT6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX11 VAMP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX11 VTI1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX12 VTI1B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PIK3CG PIK3R5 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
STX12 STX4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ARHGEF1 RHOA â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 10836144
STX3 STXBP2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
STX6 VAMP8 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
NAPA STX6 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
GNAQ PLCB3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
STX16 VTI1A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
STX19 VAMP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX19 VAMP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX19 VAMP8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX6 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX3 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
VAMP4 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 19557002
STX18 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX4 STX8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 33961781
STX8 NSF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20562859 10683148
VTI1B STX12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 GOSR2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 VAMP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 STX18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 STX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 USE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 VAMP8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX12 VAMP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX4 STX6 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
STX4 STX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 32296183 25416956
STX2 VAMP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 12828989 29360461
STX6 STX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX3 YKT6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX3 VAMP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
STX18 BET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX18 STX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
USE1 STX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX7 GOSR2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BET1L YKT6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11927603 12388752
STX7 USE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX7 STX18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX18 VAMP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
VTI1B STX18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX18 VAMP8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STX11 VAMP8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 25748427
STX2 VAMP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 12828989 24373201
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
SNAP23 VAMP3 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
NAPB STX5 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
STX3 VAMP3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BET1 GOSR2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
STX3 VAMP8 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 26553929 10336434 33961781 29360461 26186194
CFTR GNAI2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
GOSR1 NSF â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20562859 9325254 8636227
ESR1 NSF â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
BET1 VTI1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 29568061
BET1 YKT6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 29568061
GOSR1 YKT6 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
VTI1A VAMP8 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11101518
VTI1B VAMP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 27791468 26186194
SEC22B STX18 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
GOSR2 SEC22B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
GOSR1 SEC22B â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
STX7 VAMP4 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
STX7 STX8 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SRC LYN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 9169421 18070987 22581261
STX8 VAMP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 30833792 33961781
STX4 VAMP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 25416956 30833792 33961781
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
VAMP8 VAMP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12130530 10336434
STX1A VAMP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12093152 32296183 9144278
STX5 VAMP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 30833792 33961781
STX16 VAMP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 25416956 30833792 33961781
ESR1 MYLK2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 31527615 21182203 25604459
BTK PLCG2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11507089 12093870 17290227 10981967
BET1L STX5 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
BET1 STX5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
GOSR1 STX6 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
NAPA STX1A â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
CD81 GNAI2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
ITPR1 AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24947355 18250332
NSF STX7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 20562859
GP1BA GP1BB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18674540 12693941 18789323 9325245
ARHGAP35 RHOA â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
AKT1 NOS3 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24379783
GNAI1 GNAI2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
STX1A VAMP3 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
FCGR2A SYK â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
STX4 VAMP3 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
LYN BTK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11226282 8058772 11598012 8629002 8630736
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
STX7 STX12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
FYN PLCG2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8395016 16189514 16713569 7682059 12181444 15144186
STX4 VAMP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 16189514 25416956 33961781
VAMP8 STX17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33422265 23217709 31251111 25419848
STX3 VAMP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29360461 33961781 26186194 12828989
STX7 ADCY9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
STX7 STX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
STX3 STX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 30886144 33961781 26186194
NSF STX6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 20562859 33961781
STX6 STX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
STX7 STX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
GOSR2 STX6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781 26186194
VAMP3 STX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 34079125 19557002
VAMP4 STX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 34079125 19557002
VTI1A STX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11101518 28514442 26186194 33961781
STX7 YKT6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33422265 33961781 26186194 34079125
STX6 VAMP8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 11839770 19557002
STX6 STX18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
VAMP4 VTI1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 11839770 33961781
GNAI1 GNAI3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HRAS PIK3CA â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
STX7 VTI1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SNAP29 STX7 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NAPA SEC22B â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NAPA STX5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
STX16 VAMP4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R2 PIK3R3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
STX6 STX7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
GP1BA GP9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PIK3R1 PIK3R2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ITGB1 TLN1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FN1 ITGB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
NAPB STX16 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
VAMP4 VTI1A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SNAP29 STX12 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
VTI1A STX8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11101518 33961781
NSF STX12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20562859 33961781
VAMP7 STX4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 14993220 12853575
RHOA ITPR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 12766172
CFTR STX1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9384384 12209004
STX3 VAMP3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26553929 33961781 26186194 9614185 12828989 9701566
GOSR1 BET1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11927603 29568061 33961781
STX7 BET1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 29568061 26344197
BET1 GOSR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 33961781 29568061
STX7 VAMP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 12175335 33961781 26186194 11278762 34079125 19557002
VTI1B STX6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27791468 33961781 26186194 34079125
USE1 STX18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 26186194 19369418
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 NOS3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
STX3 VAMP2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BNIP1 STX18 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
GNAI2 GNAI3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SNAP29 VAMP7 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NAPB SNAP29 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
STX12 VAMP7 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GNAS PTGIR â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GNA13 TBXA2R â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
LYN PLCG2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8395016 10981967 7682059 12181444 15144186
STX8 VTI1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 16189514 11101518 10683148 33961781 26186194 21516116
STX8 STX7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11101518 12175335 33961781 26186194 34079125
STX4 STX12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 33961781 26186194 34079125
GOSR1 STX12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 33961781 26186194
STX12 VAMP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
STX12 YKT6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
STX7 STX4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 33961781 26186194 21516116 34079125
STX6 STX4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 33961781 26186194 21516116 34079125
STX11 VAMP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 33961781 10036234
STX7 VAMP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 34079125 26344197
BET1 STX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11927603 29568061 9094723 33961781
GOSR2 STX6 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PLCB1 GNAQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16754659 12193606 11753430
STX6 STX7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 33961781 26186194 11278762 34079125
VAMP3 STX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27791468 33961781 26186194 34079125 11839770 19557002
VAMP4 STX16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 11839770
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ARHGAP35 RHOA â—¼   GTPASE_REACTION ✅ - 0.89 0.89 Signor 32203420
GNAQ TBXA2R â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
FXR2 LCP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SNAP29 VAMP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
STX8 VAMP5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LYN PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318860
LYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11782428
MAPK1 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK14 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15649893
MAPK3 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MATR3 SNAP23 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PIK3R1 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8596638 14665640 11733063
STXBP4 STX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12855681 15753124 10394363
FGA TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
PPP1CB NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
STX6 STX12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17159904 33961781 26186194 34079125
STX12 VAMP4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 17159904 26186194
SYK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15536084
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
STXBP2 STX11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28265073 19804848 19884660
STX11 SNAP23 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNAP23 WASH2P â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNAP23 IKBKB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 25083866 23613522 18692471
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
FYN ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18541700 23144976 11536198
GNAS ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690
GNAS ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
RHOA ARHGAP35 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18829532 9407060 16308318
ARHGAP35 RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 12429740 16707504
ARHGAP35 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 10592173 32203420
FN1 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGA RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
RAP1A APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17624957 15469846 16757337
VAMP3 STX4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 10820264 34079125 12130530 12828989
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
FGG SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGA SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
SRC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
ROCK1 MYL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12185584
PPP1CC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14633703
VWF ITGB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB ITGB3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
PRKCA ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16014375 10592173 17570479
PRKCZ NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24379783
PRKCZ AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353613 9512493
PRKCA ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8206971 7759492
FN1 APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
CEBPD PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12791769 1714459 11278589
CEBPD CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499410
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
PRKACA ORAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31652779 31036819 26269433
PRKACG NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11729179
GOSR2 STX5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 9094723 9647643 11927603 11035026
GNAQ BTK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9770463 11742120 9305846
PTGIR GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10446129 31160049 11443126
STX7 VAMP8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11101518 33422265 33961781 26186194 11278762 34079125 19557002
STX7 VTI1B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12175335 33961781 26186194 34079125 12114520
STX6 VAMP4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 17159904 10359608 25419848 33961781 34079125 11839770 19557002
STX6 VTI1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17159904 33961781 26186194 34079125
VAMP4 VTI1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11839770 33961781 17159904
FGB RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGA RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
RAP1B APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17624957 15469846 16757337
ESR1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23167795 16423895 19366879
ESR1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PPP1CA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
GNA13 ARHGEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11313914 15951850 22661716
PPP1CC NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
PIK3R2 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22402981 8596638 11733063
GP1BA VWF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12183630 6336654 15039442 7690774 12087105 2690940
PRKCI NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24379783
FGA APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
F2 F2RL3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
FGB ITGA2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGB PIK3R3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AKT3 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
VWF APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FGG APBB1IP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
VWF ITGA2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
STIM1 ITPR1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 19249086 18596693 18187424
AKT2 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
STIM1 ITPR2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 19249086 18596693 18187424
STIM1 ITPR3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 19249086 18596693 18187424
MYLK3 MYL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11942626 12429016 15946647
STX12 VTI1A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NAPA VTI1B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
STX7 VAMP8 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ITGB3 TLN1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
SNAP29 STX1A â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
STX4 VAMP2 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
RHOA ROCK2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 31871319 11350930
STX5 YKT6 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
STX5 YKT6 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 11927603 33961781
STX7 VTI1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
STX3 VAMP8 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SNAP23 STX1A â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
SNAP23 STX3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
SNAP23 STX2 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
NAPB STX3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
STX6 VAMP3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ORAI1 STIM1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
STX7 VAMP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
PTAR1 YKT6 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STX12 STX6 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
STX6 VTI1B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
F2 F2R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 GP1BA â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
NAPA STX16 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
STX8 VTI1B â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
RHOA ROCK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VTI1A YKT6 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PIK3CB PIK3R2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
GNAI2 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
GNAI1 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
NAPA STX12 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
NAPA STX7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
APBB1IP TLN1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PIK3CA PIK3R3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
STX6 VTI1A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HRAS PIK3CG â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
STX6 VAMP4 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
PIK3CB PIK3R1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
GOSR2 STX5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
GOSR1 STX5 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
F2 F2RL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PPP1CB PPP1R12A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
STX8 VAMP8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11101518 33961781 19557002
VAMP8 STX4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12130530 29360461 10820264
STIM1 ORAI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24996186
STIM1 ORAI1 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 24996186
ORAI1 STIM1 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 21427704 8186898
F2 FGA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NAPA NSF â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
FGB FGG â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
STX12 VTI1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 17159904 26186194
ROCK1 RHOA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21281639 31431478 8816443 14660612 12773565 8798490 31871319
STX18 USE1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
FN1 ITGB3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GP1BA VWF â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
SEC22B STX5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
STX4 VAMP2 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 8760387 25416956 32296183 10820264 12417022 8770861 12517971 10194441 30217970 29360461 34079125
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
PIK3CD PIK3R1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ITGA2B ITGB3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGB â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
FGA FGG â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PIK3CA PIK3R2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
STX1A VAMP2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12093152 32296183 9030619 19293945 7553862 10449403 10100611 11832227 23100443 20798282
GOSR1 STX5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 9094723 9647643 9325254 12388752 11927603
STX4 STXBP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STX1A VAMP2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COL1A1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11359786 7688313 11856343 2156854
COL1A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7716514 10464311 7688313
ITGB1 LYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
LYN FCER1G â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12524384 19909365 21910624 24445665 26552706 8064233 8132624 8478617 8892616
GNAI2 LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
LYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 9820500 24129562 10022120 18818202 21469132 24607955 18083107 17389395 19285079 11536198 10592173 25045209 7797565 11380624 9857068 7513017 30923129 8621719 10477689 7831290 15701717 27258042 19369195 28082678 8666899 9535867 8657103 14871838
LYN MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11131153
LYN PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21780115 15032589 11526404 23109003 22880054 10488096
LYN PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 19901323 8395016 12181444 11606584 14656219 7682059 15144186 10469124 11507089 16497976 10981967 15212693
LYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21780115 29145629 12506011 18453587 11526404 10455108 15032589 23109003 23180781 9334184 15149544 10194437 22880054 11598010 10488096
LYN FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8756631 9268059
LYN BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 18083107 8629002 12573241 11598012 19369195 10051622 9012831 8630736 9730885 10811866 9052864 8058772 11226282
NRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
KSR1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 9858547 8248196
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17081983 15547943 19114553 17570479 18280113 21185392 19541618 8381049 19565474 7766652 10978317 18632668 9468497 17178906 8636128 11737068 32559461 18775330 12576304 12885780 15212693
MAPK1 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11287604 11481231
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 STIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25562429 22298426 23687376 24114840 19881501 33023909 25447552 28935720
FYN MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15735648
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8636128 20068231 10978317 9468497 8910365
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK3 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
KSR1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 8248196
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11287604 11481231
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 PLA2G4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8636128 17081983 19541618 8381049 19565474 18775330 9468497 15547943 19114553 10978317 17178906
NRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
KRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9069260 25241761 10212255 11313862 9150145 16713569 15021914
SYK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16921024 15536084
FYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8294442 8394019 7515100 17570479 16713569 7520528 1652056
ESR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11029009 11689445 16169518 23065768 16713569
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
PIK3R1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8596638 25241761 20713702 27107012 11733063 21825134 32814053 26496610 8139559 14729945 10358930 14665640
PIK3R1 PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 25241761
PIK3R1 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9113989 8596638 21827948 12147247 11733063 22020336 24165795 31031754 14665640
AKT2 STXBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15753124
ITGA2B TLN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
TLN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19118207 12606711 7716514 3124107 10497223 19118212 21947080 11279249
TLN1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19118207 12606711 17218263 35044719 11932255 10497223 9065427 18156175 32196115 12535520 20739287 16546176
COL1A2 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11359786
COL1A2 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1693626
COL1A2 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2156854 17485091
ROCK2 PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
RHOA PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1CB ROCK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
MYL12B PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
FYN FCER1G â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
FCER1G SYK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12731048 15081523 15099567 20814939 23414611 2451784 7590867 9625766 9952373
FCER1G SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9280292 17145710 8071371 8810294 8663460
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
GNAI3 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933 8327893
GNAI3 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
PLCG2 LCP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11390650 20484116 10811803 12471105
FYN LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648627 9047237
SYK LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12817019 9047237 15388330 10660534 22534133 17353368 21725281 22786724 23901140 8892604 16189514 28736554 8702662 11046020 17148460 22267732
SYK FYN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
FYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7797565 7513017 17570479 10477689 9535867 16713569
SRC SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7513017 17353363 17570479 16189514 9389695 23100514
SYK PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9531509 20068231 12881490 17192257 15583006
SYK FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9280292 9632805 11141335 15136586 8756631 9295288 8663460 9268059
SYK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771181 19783684 12470302 16449524 14656219 10469124 10933389
SYK BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18083107 8629002 28368423 11598012 28359287 29455639 19369195 10051622 9012831 8630736 28088788 11226282
SYK ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17353363 18088087 11940607 15699036 11042121 8631894 11723131 11719224
ITGB1 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FGA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15031111 7716514
PRKCA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12138200 12435334 20926684 11700305 10592173
FN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9842903 22451694 17015452 18480047 19738201 7688313 1694173 6325925 25237190 26456826 10772816 7626807 21985969 6284125 1532572 11010812 8120056
PIK3CD FYN â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9590251 7537740 8995358 9259313
FN1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FYN PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7515100 1334406 16713569 1652056
FYN PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19901323 8395016 12181444 11606584 14656219 7682059 15144186 11507089 16497976 16713569
FYN ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14761954 28598420 18056410 8633244
FYN FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8756631
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
GNAS ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9228084 6935665 210183 17652154 2022671 21406690 32196115
GNAS ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9228084 9748257 9268375 21406690
PIK3R2 HRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
HRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
RASGRP1 HRAS â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10807788 12782630 14764585 15184873 17496910 24027568
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9069260 9113989 9235916 21779497 11739523 10545207
HRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9069260 9727023 17145710 10922060 11136978 21779497
HRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 9069260 9113989 8052307 24412244 17540175 9931431 11313862 14724584 10592173 9150145 8665852 10783161
SRC ARHGAP35 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
ARHGAP35 RHOA â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 17517963 18829532 22411312 8360177 9819392
SRC ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19901323 21937717 18541700 20068231 9819392 10592173 11309200 16497976 15592455 17570479 16513268 7542246 30664792 17016520 32540970
ROCK1 ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19103606 19673492
ITGA2B RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SRC RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
ITGB3 RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
RASGRP1 RAP1A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
RAP1A RASGRP2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
PRKACA RAP1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8463283 9867809
RASGRP2 RAP1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702343
KRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KSR1 PLA2G4A â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10843677 11034387 11062502 11385609 11907067 14764585 15169888 15536084 15547943 15735649 17178906 17395718 18775330 19114553 19541618 19565474 22435554 24027568 8381049 9510155
ROCK2 RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11283606 15699075 8816443 11294240 8617235
PPP1R12A RHOA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
RHOA ROCK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11698448 11729192 11739775 11992112 12194823 12361600 12740575 14657501 14744429 15761148 17517963 18037882 18423981 20535745 21178402 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
ARHGEF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 12748184 32203420 9113980 9641915 10836144 11149925
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
RHOA ROCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23109003 12727213 17673200 17446864 11350930
RHOA ROCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 17145710 12361600 25010901 23151663 7479854 27048821 22949611 21281639 26885855 8798490 12727213 17673200 11729192 8816443 10592173 11698448 27066895 11739775 11992112 20535745 18423981 24857661 21178402 23109003 9660866 9822605 17517963 14660612 15774750 12740575 14744429 9535835 12773565 15761148 24919149 26192618 9362522 18037882 14657501 12194823
SRC APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SRC RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SRC PIK3CA â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 12682286 15314172 20861220 18657504 11689445 12431978 25587652 11044445 22266855 11029403 11029009
GNAI2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PRKCZ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 10527887 11447289 19615955 16488589 6321473 8321321 12845332 11313945 16189514 12040186 19568798 15567848 14585353
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
GNAI1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 10753828 9722546
PRKCI SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 11713277 15567848 14585353
SRC PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 30819914 12181444 11606584 14656219 7682059 15144186 11507089
SRC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12750372 10592173 17275257 10830300
SRC PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21780115 15032589 11526404 23109003 22880054 10488096
SRC MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12408982 20861316 11113114 10362724
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
SRC BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19109164 23170196 8629002 29455639 10051622 8630736 26165234 9052864
PPP1R12A ROCK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
ROCK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 11384979 15723050 18767875 19607793 19701943 9354661 10926869 18077418 18669648 10579722 15826939 12220642 26701920 17525332 19997641 12600888 11931630 11719507 15814590 8662509 12563012 12919947 10601309 18212344 12359219
ROCK1 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8702756 11283607 26169356 12185584
RASGRP1 RAP1B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
RASGRP1 KRAS â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 11221888 10934204 17283063 10777492 10835426
RASGRP1 NRAS â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 11221888 10934204 17283063 10777492 10835426
FN1 ITGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7688313
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18578522 10896934
AKT1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759249 20166139 11756412 10376603 11923280 12446767 16697215 11044445 20398329 18372248 11696579 16126727 16839566 15808505 20138985 20299462 10908731 20363286 11988487 11425855 20214616 23103584 11729179 16043647 17570479 12171920 25460366 27322328 11978735 15169778 11029403 25241761 19654415 10949026 18048761 11715018 12791703 24379783 18636226 9812896 23397142 17680028 10376602 12431978 10722653 20832730 18570873 25009123 17052453
AKT1 ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24947355 18250332 16332683 18955969
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
ITGB3 RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
ITGB3 APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
FN1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11423542 1694173 18480047 1532572 8663002 17015452
KRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
NRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PRKCZ IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10195894 9689078 10779355 11460167 10022904 10356400
PRKCZ AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9512493 25241761 12162751 9305920
PRKCA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 33539947 25814956 12384459 27191895 18622039 27106139 12574113 12869534 21797845 11729179 21757745 25020117 28833096 12644458 24612481 24379783 16527893 16527820 12952971
PRKCA ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8383119 8900209 9366262 7938004 9268695
PRKCA TBXA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 16956790 18578522 10827090 24490858 11516166 7961988 9054415 9915793 17466390 11015313 9560198 15100160 11504827 12370102 14530262
PRKCA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9015864 11278470 9349568 2211670 9307019 17570479 21338571
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
PRKCA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20802526 34333552 23331499 25713064 27791178 18458061 9922370 18182391 16483930
PRKCA PRKG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 12609995
PRKCA FERMT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 32730588 25609252
PRKCA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11278298 9660757 15302935 10893237
PRKG1 TBXA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11516166 9915793 17466390 9560198 14530262
PRKG1 VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10922374 20058876 8182057 15694326 20166139 14679200 7925440 23867907 94237860 20483741 17570479 17287340 9685341 21702043 15066263 15212693 10851246 12576312
PRKG1 PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19651622 11278298 10893237 9660757 15302935
PRKG1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19120700 10579722 15194681 10567269
PRKG1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 92316961 17570479 10581361 1377674
FN1 ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8663002
SEC22B NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
GNAI2 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI2 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2121366 8327893 19703466
GNAI2 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI1 ADCY6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23109003 15539636 7935349 16460834 11376933
GNAI1 ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9748257 23109003 15539636 7935349 16460834 11376933
STX6 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
STX16 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
VAMP4 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
GOSR2 NAPA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
VAMP4 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
GOSR2 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
STX16 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
STX6 NSF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
NSF BNIP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
NSF VAMP3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
NSF VTI1A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
NSF STX18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
NSF USE1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16912714 8221884 8620540 19164740
AKT3 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20016067 17680028 20214616 17688959 20398329 16537363 17052453 19575820
PRKACA TBXA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11749379 10827090 7961988 12147288 14530262 11389883
PRKACA RAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8463283 19651783 27760305 12089143 1551424 90343822
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA GP1BB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 19651622 20058876 20166139 89359414 18088087 2504723
PRKACA GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12399457
PRKACA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 28615442 9660757 10893237
PRKACA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15319357 12522122 34204249 10376603 31923467 16839566 33429979 34026871 16946136 10908731 10671564 16270749 11729179 12171920 26132171 11978735 17572401 24379783 10376602 16873402
PRKACA SNAPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15269257 21356520 11283605
PRKACA ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 2847175 1847804 8132598 19144319 12529267 14741364
PRKACA VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8182057 20058876 20166139 14679200 7925440 8836115 94237860 16197368 10851246 9685341 17287340 10922374 12576312
GOSR2 YKT6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22013193 19758564 24119662 19164740
STX16 RAB9A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
RAB9A VTI1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
PIK3R3 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8596638 22402981 9415396 11733063 26496610 25814554
NRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8052307 7820549 9150145 8665852 21779497
TBXA2R GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23962128 20590159 15134434 12726995 12193606 9152406 15782186 21940795 31160049 12399457
GNAQ PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11753430 1309799 12193606 16754659 8245028 8387502 1322796 1846707
ITGA2B RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
RAP1B RASGRP2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16076873 15469846 15334074 16757337
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
KRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9727023 16189514 10542052 21779497
F2R GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8290554 20223821 10922491 16189514 22318735 22972936 21331223
TBXA2R GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8290554 10395940 15782186 31160049 10488151 12399457
GNA13 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14607242 9641916 9641915 16189514 12681510
NRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
KRAS PIK3CB â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
F2 GP1BA â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
VWF GP1BA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 19286885 15039442 6336654 12087105 7690774 12183630 2690940
PIK3R2 KRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
KRAS PRKG2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 23943869 26590425 9436858 11585916 29311131 20802526 25713064 16483930 24033119 27697864
PIK3R2 NRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
STIM1 ORAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 21876174 21427704 22446186 19249086 35439114 24954132 24996186 22451904 22464749 19706554 30481768
FGA BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
F2 FGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25241761 2133223 2742826 1587268
F2 GP1BB â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 VWF â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 19240027 8052958 2104766 15705787 1851341 2109644 1973901
F2 GP9 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 GP5 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 10781579 8338946 2019570 9888880
F2 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9058715 10978167 15707890 10644723 14652070 11356985 23450633 18250335 12563219 22972936
F2 F2RL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1273221212732210 12732212 22318735
F2 GP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2207326
FGB BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
FGG BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
BTK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 19901323 19690332 15184383 16497976 33419778 34141433 15509800 30344948 12235209 14656219 17290227 12780340 12181444 11606584 21074890 7682059 11507089 15144186 22409342 29455639 17239630 10498607
ITGA2B APBB1IP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
VWF ITGA2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 31035301 1737795
MYLK MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23790394 24144337 26827725 29046396 17924679 21345328 11815633 28878690 11062269 19690332 18773891 20510202
MYLK MYL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11384979 15710622 15946647 22120626 16460276 11278951 12429016 18984162 15567063 12185584 26334100 11942626 14592950 27735862 17408635
PPP1R12A ROCK2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
ROCK2 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17127075 11062269 26664257 15281089 21242007 28971603 10579722 10047526 11331307 11739394 29955616 12220642 26701920 25168281 23825105 19997641 12600888 27251065 15003930 11931630 11719507 27725371 12563012 12919947 21273559 10601309
MYL12B PPP1R12A â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PRKG2 PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19651622 11278298 10893237 9660757 15302935