Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBA52 ZRANB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
VPS37B VPS28 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
STAM2 VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM VPS28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS28 TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HGS ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
ARRDC3 HGS â—¼   COLOCALIZATION 2.0 0.8 intact 23208550 8428323
CBL ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
SH3KBP1 ASAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5219572 17255943
ASAP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
SH3KBP1 ASAP1 â—¼   COLOCALIZATION 2.0 0.8 intact 17255943 5219572
ASAP1 SH3KBP1 â—¼   COLOCALIZATION ✅ 0.8 0.8 mint 5219572 17255943
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
CBL MET â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215187 11894096
CBL SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095 16713569
CBL FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CHMP3 STAMBP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
GRB2 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SNTA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11551227 11278583
STAM2 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VPS37C HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS37D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS MVB12B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
MET HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 8380735
ITCH SH3GL2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5216835 14684745
SH3GL2 ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 5216835 14684745
JAK1 STAM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10993906 5213009
STAM2 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10899310 16713569
STAM MED28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033846 16964398
STAM2 MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM MVB12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 MVB12B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM MVB12B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SH3KBP1 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
VPS37A STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS37D STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
VPS37C STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
STAM UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
UBB STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAMBP STAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STAM2 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
STAM2 VPS37B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 UBAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 VPS37D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
STAM2 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10899310 16713569
UBB STAMBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAMBP UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ITCH RPS27A â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
MYC RPS27A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
GRB2 VPS28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARRB1 ITCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18544533 17947233
ARRB1 HGS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
NTRK1 CBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21570973 25921289
NTRK3 CXCR4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LITAF FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LITAF FGFR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LITAF UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RPS27A STAMBP â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
VPS28 UBAP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 21757351 26186194 28514442 31203368 24284069 22405001
CBL ITCH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
JAK3 CXCR4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10506573 16189514
EPS15 STAM2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12551915 16713569
STAM2 JAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 10899310
SH3KBP1 UBB â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
STAM UBB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
STAM2 UBB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ARRDC3 UBA52 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
STAM2 JAK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 10899310
STAM2 TYK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 10899310
RPS27A ZRANB1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CBL EPHA2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TSG101 VPS37D â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
UBC UBQLN2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
MET CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6538879 18273061
MET CBL â—¼   UBIQUITINATION ✅ 0.86 0.86 mint 11894096 5215187
STAM USP8 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CLTC HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
PDCD6IP SH3KBP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TSG101 UBAP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBAP1 VPS28 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
UBAP1 VPS37A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
GRB2 STAMBP â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ARRDC3 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
EPS15 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17474147 7797522 19109251
JAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8536716 11527382
STAM STAMBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EPS15 HGS â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PDCD6IP TSG101 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SH3GL2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SNTA1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11278583 11551227
MED28 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16899217 15467741
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
STAM2 JAK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10993906 16713569 10899310
TSG101 VPS37C â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ASAP1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HGS RPS27A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
TSG101 UBA52 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ITCH UBC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
SEC24B SEC31A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
STAM ASAP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0509166103 7102318 16636290
GRB2 ASAP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21706016 31980649 20936779 21988832 28514442 19380743 17474147
ASAP1 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0509166103 7102318 16636290
MYC CD79B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10229837 11145693
CXCR4 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17158356 10506573
MYC FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PDGFRA GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8536716 17474147 8950973 7500025
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
MET HGF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18593464 20624990 19433454 22897854 8380735 15167892 16537482 17981115 28205554 17804794 28628118 1846706 18495663 1655405
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC UBA52 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ARRDC3 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
RPS27A STAM2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
UBC USP8 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EPS15 UBC â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RPS27A UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
UBB UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MVB12B VPS28 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CBL MET â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
UBA52 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
VPS28 VPS37A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CBL SH3KBP1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
STAMBP UBC â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
RPS27A SH3KBP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
TSG101 UBB â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
TSG101 VPS37A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MVB12B VPS37B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SEC13 SEC24B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PTPN23 STAM2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A STAM â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MVB12B TSG101 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PTPN23 UBAP1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MVB12A VPS37B â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SH3KBP1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6170483 15090612
RPS27A TSG101 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
HGS STAM2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SH3KBP1 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
STAM2 STAMBP â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CHMP3 STAMBP â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
MVB12A TSG101 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ARRB1 CLTC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
STAM UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
SEC13 SEC31A â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
STAM2 UBC â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
VPS28 VPS37B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TSG101 UBC â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MVB12A VPS28 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TSG101 VPS28 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TSG101 VPS37B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
VPS37C VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37D VPS28 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
TSG101 VPS28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 26871637 19060904 26186194 11134028 15218037 25416956 21757351 11916981 31515488 16189514 32296183 12663786 14505570 24284069
STAM2 CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SH3KBP1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 20130058 20711168 12618476 11894095 16407834 16713569 11071869 19268472 25472714 17306257 22262777 15456872 11152963 10679202 15962011 25036637 15107835 22833562 11067845 11894096 12177062 17675467 21830225 12135478 24167568 16228008 12874286 17072306 15090612 14596919
CBL PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 9234717 10347229 18988627 17635922 10514377
CBL MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16397241 15123609 23331499 25241761 21222362 11894096 18672314 21163258 19450681 18273061 35309168 17533376 19433454 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CD79B GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
CD79B SH3KBP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
CXCR4 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23109003 11406370 12495636 16189514 17169327 10506573
HGF EPS15 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
MET EPS15 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7797522 17474147 19109251
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
FGFR4 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
HGS HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF MET â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11290563 12649206 15059978 16212809 17145802 18633355 19631971 20303741 22763439 23402812 23667593 26366398 26819959 27474009 28475121 9242465
HGF MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 17145710 22897854 15167892 1655405 20624990 19433454 23331499 17804794 1846706 28475121 22001117 16537482 15218027 27147579 24362531 17667909 16397249 20178463 17981115 28534512 8380735 18495663 14685170
HGS SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
ITCH SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14684745 17038327 26613292
JAK1 TYK2 â—¼   PHYSICAL_INTERACTION 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK1 JAK2 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 JAK2 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10485906 11160275 11306493 11371360 11489965 11579131 11777960 11867689 11870632 11964313 12223527 12401408 12413632 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 15099563 15356132 15573129 15634932 15778339 15811952 15814715 16243976 16286920 16413922 16424049 16713974 17016554 17404308 17485448 17559085 17683974 18209571 18250477 1825141 18272812 18451175 18555777 18555778 19581928 19833085 20038811 20138012 20184663 20237318 20406969 20510870 20581311 20819927 20856220 21097505 21115385 21149606 21411734 21469115 21840487 22595692 22754783 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 24658051 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 6425450 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545 9864217
JAK1 TYK2 â—¼   SHARES_COMPLEX 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK3 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11641425 19901323 20135364 17259970 12207328 10825200 11909529 15659558 12559972 9553136
JAK1 STAM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10899310 10993906 16713569
JAK1 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702790 19901323 7504784 7589562 15659558 30029643
JAK2 TYK2 â—¼   PHYSICAL_INTERACTION 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
JAK2 TYK2 â—¼   SHARES_COMPLEX 73.0 1.0 ACSN 10485906 10807786 11160275 11306493 11371360 11867689 11870632 12223527 12244147 12372421 12401408 12496409 12754507 12818165 1439146 14610620 14657224 15099563 15356132 15546391 15573129 16243976 16413922 17404308 17485448 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21042762 21097505 21115385 21469115 21840487 22077060 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24204259 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8683106 8700208 8837607 9535722 9834059 9845545
JAK2 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 9133424
JAK3 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 10899310 9133424 16189514
STAM2 MET â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
MET STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
VPS37A MVB12A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37C MVB12A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37D MVB12A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37D MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37C MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
TSG101 MVB12B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
STAM SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
STAM2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
USP8 STAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 10982817 20736164
VPS37D UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37B UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37C UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139
VPS37A UBAP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 21757351 22405001 15218037 18005716 20448139