Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
XRCC6 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TINF2 TERF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11701125 5214767
TERF2 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
TERF1 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
BRCA1 TINF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34112789 29656893
BRCA1 POTE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34112789 29656893
BRCA1 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16628214 30804502
TE2IP MDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 15383534
SMRC2 MDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 29656893
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
NBN TE2IP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22939629
RIF1 TE2IP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 12753906
TE2IP XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15100233 15383534
ARL4D TERF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARL4C TERF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARL4C TE2IP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZBT10 TE2IP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 30629181
ARL4D TE2IP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BRCA1 TERF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 19797051 29656893
BRCA1 TE2IP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 34112789 29656893
BRCA1 TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 25184681 19797051 29656893
TAD2B TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FBRL TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PR40A TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CC106 TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DCR1B TERF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16730175 26496610
CC106 TE2IP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FBRL TE2IP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DCR1B TE2IP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 24981860
TAD2B TE2IP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FBRL RECQ4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 29229926 33961781 26186194
BRCA1 SMRC2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10943845 26831064
TERF1 TE2IP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15316005 16880378 26496610 33961781 26186194
ACD TE2IP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 15316005 15383534 16880378 26496610 33961781
TE2IP POTE1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 15316005 15383534 16880378 26496610 33961781
TE2IP PPM1G â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21044950
ACD TERF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15231715 16880378 15383534
TE2IP H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21044950 30804502
TE2IP RECQ4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29229926 21044950
TE2IP NUMA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21044950
PPM1G XRCC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30585729 28330616
TE2IP MRE11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 15100233 15383534
TE2IP GPKOW â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21044950
POTE1 TERF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15383534 19651898 19287395 16880378 26496610 20811636 33961781
PR40A TE2IP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
TE2IP SMRC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21044950
TE2IP CI078 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21044950
TE2IP DPOD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21044950
TE2IP PRP16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21044950
RAD50 TERF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ACD TERF1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TERF2 XRCC6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ACD TERF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15383534 15231715 16880378 26496610 33961781 26186194
TE2IP UCHL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21044950 29126443
NBN BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10426999 18171670 19244116 12124328 10783165 25659039 25184681 25939603 11504724 29656893
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
TERF2 NBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 19287395 10888888
MRE11 XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
XRCC6 TERF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21044950 26496610 10984620
TERF2 MRE11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 19287395 10888888 18212065
TE2IP PP1RA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 19287395 26496610
MDC1 RAD50 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BRCA1 MRE11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10426999 10783165 17349954 25184681 23530059 16391231 11353843 24413181 11504724 29656893
BRCA1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10426999 18171670 12124328 16713569 10783165 25084169 25184681 16260778 16391231 11504724 29656893
MDC1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 29656893 14519663 12607005 12607003 18583988
MDC1 NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15377652 30179224 12607003 18678890 29656893 27590578 25064736 20460517 19804756 23115235 14519663 15201865 12607005 20224574 18001824 18583988
MDC1 MRE11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 29656893 20081839 14519663 12607005 12607003 18583988
NBN MRE11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 11238951 17612497 22941933 23530059 15758953 11062235 10426999 19244116 10783165 18458108 21884979 22464731 33558481 24413181 26455393 12447395 12679336 28369484 22078559 34038735 22231403 12419185 22939629 34348893 17526493 12861053 17500065 12750284 9705271 28363998 30440001 24981860 19270065 12607003 15734743
TERF2 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19287395 15100233 10888888 18212065 22939629
TE2IP RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22939629 15100233 15383534
SLX4 TE2IP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19596235 22902628 31495888
SLX4 TERF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25533185 23994477 19596236 19596235 32398829 24012755 31495888
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
TE2IP XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21044950 15383534 15100233 26496610 34079125
POTE1 TINF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15316005 21044950 15383534 12768206 15181449 15231715 16880378 26496610 20811636 33961781
TINF2 ACD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 21044950 25416956 16713569 15383534 15181449 15231715 25910212 16880378 26496610 33961781
TINF2 TERF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23307557 15316005 28514442 21044950 15383534 15181449 15231715 19287395 16880378 15292264 20811636 26496610 33961781
TINF2 TE2IP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15316005 15383534 15181449 16880378 19287395 26496610 33961781
DCR1B TERF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21217703 20479256 26496610 16606622 16730175 33961781 24981860
TE2IP TERF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21217703 19287395 10888888 21829167 23307557 15316005 23086976 28082411 26450775 26496610 27214791 10850490 21044950 15383534 16880378 22939629 29126443 19164295 19651898 15100233 24981860 14565979 34079125 26344197
ACD POTE1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17237768 16189514 21044950 16713569 17632522 15383534 15181449 15231715 17237767 16880378 26496610 33961781 26365187
ACD TINF2 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
TERF1 TINF2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
POTE1 TERF1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 12768206 26496610 20811636 33961781 26186194
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
RAD50 NBN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30179224 12607003 12124328 11238951 17612497 22941933 23530059 24651726 15758953 11062235 10426999 10783165 22464731 19197236 12447395 12679336 26215093 22939629 34348893 17526493 17500065 9705271 16391231 30440001 24981860 26344197 15734743
TINF2 TERF1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 17589526 15316005 21044950 15133513 25416956 19487455 15383534 15181449 16880378 10581025 26496610 20811636 28216227 33961781 26186194 16169070 11701125
NBN TERF2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SLX4 TERF2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
TERF2 TINF2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAD50 MRE11 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 30179224 12607003 30733337 10888888 23530059 24651726 11062235 17694070 10783165 31501894 33558481 19197236 24413181 26455393 10508516 16163361 28369484 26215093 34038735 8756642 22939629 34348893 17500065 12750284 9705271 16391231 27173435 28363998 24981860 19270065 11504724 26344197 15734743
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
XRCC5 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RAD50 MDC1 â—¼   PHYSICAL_INTERACTION 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RAD50 MDC1 â—¼   SHARES_COMPLEX 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
XRCC6 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MRE11 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TINF2 TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
TINF2 TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
ACD TINF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 16880378 15181449 25416956 21044950 15383534 31515488 26496610 16713569 15231715