TPT1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
UBE2I
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
CHEK2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19001859
12364621
|
ATM
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
CHEK2
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16651405
10724175
|
ATM
|
H2AX
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16858402
5218840
|
XPC
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16849332
|
NBN
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
CHEK1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0706013104
17686975
|
BRCA1
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
ATR
|
UBE2T
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20670894
23723247
|
ATR
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791985
16327781
|
H2AX
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
19146767
11673449
|
ATR
|
BRCA1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
23422745
|
TRIM28
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942393
|
YY1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21666725
|
EP300
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23353771
23285190
|
BRCA1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574597
|
PCNA
|
CHAF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218806
16826239
|
CHAF1A
|
XPC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19279666
7263364
|
DDB1
|
CHD1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
19661379
|
PARP1
|
CHD1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
19661379
|
XPC
|
CHD1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
19661379
|
CHD1L
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
19661379
|
NBN
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19001859
12364621
|
RNF8
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19001859
12364621
|
CHEK2
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19001859
12364621
|
RNF8
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16651405
10724175
|
NBN
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16651405
10724175
|
CHEK2
|
H2AX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16651405
10724175
|
CHEK2
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
16651405
10724175
|
CHEK2
|
SOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
30576923
24647101
|
RNF8
|
DCLRE1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25512557
15574327
|
H2AX
|
DCLRE1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25512557
15574327
|
NBN
|
DCLRE1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25512557
15574327
|
MDC1
|
DCLRE1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25512557
15574327
|
DCLRE1C
|
XRCC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16857680
|
PARP1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
23319653
|
DDB1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
XPC
|
DDB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20368362
|
PARP1
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
23319653
|
XRCC5
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20368362
|
NKX2-5
|
DHX9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12754203
15972800
|
SENP3
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7941484
19680224
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
NBN
|
EP300
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21108945
8058069
|
EP300
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20428248
|
EP300
|
DDX17
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20663877
|
EP300
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20488183
|
EP300
|
PARP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16204234
|
EP300
|
H2AZ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19056256
|
TRIM28
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
UBE2I
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14651848
16906147
|
PRKDC
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PARP1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MYC
|
IKBKG
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20970423
8045055
|
PRKN
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20301198
|
SMARCA5
|
KAT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2AX
|
KAT2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20224553
|
TOP1
|
LIG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
13679147
|
SPI1
|
MACROD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19698236
|
RARA
|
MACROD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19698236
|
AR
|
MACROD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19022849
20610535
|
UBE2I
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
MEN1
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12837246
|
HIF1A
|
MSH6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18511603
15780936
|
CEBPA
|
MYC
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
11340171
20581311
|
ERF
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17699159
17525531
|
PDX1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11687580
17317781
|
ZBTB7A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17189472
|
ERG
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25277175
20820186
|
MYC
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11318876
10528192
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
MYC
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9988278
|
NBN
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
ORC6
|
ORC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0707260105
18234858
|
HSPB1
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBC
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11689694
5214752
|
OTUB1
|
SOD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PARP1
|
LRRC31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PARP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
PARP1
|
SPTA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
AR
|
PARP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18945670
20610535
|
PARP1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18314489
|
PARP1
|
H2AZ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1429884
|
PHF1
|
TFCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
XRCC4
|
PNKP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15385968
5217205
|
POLA1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9660172
2165567
|
POLA1
|
PRIM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15132993
9115215
|
POLA1
|
PRIM1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15132993
9115215
|
POLE3
|
CHRAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
PRKDC
|
RNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HOXB7
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17308091
|
CSNK2A1
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20711232
|
RAD23A
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RNF8
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
SMARCA5
|
CENPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19410539
19398759
|
SMARCA5
|
H2AFX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19092802
19234442
|
TFAP2A
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19701232
18754863
|
SPI1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17967894
7988559
|
PPARG
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16556873
19912441
|
XRCC5
|
TPT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
TPT1
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
H2AX
|
TRIM28
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8149296
21317870
|
UBE2I
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18082607
|
UBC
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6603858
18588880
|
UBE2I
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17693435
16030353
|
PCNA
|
XPC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19279666
7263364
|
UBC
|
YBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218767
16797541
|
MECOM
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1119229109
22308434
|
YY1
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19483472
|
YY1
|
SPTA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12759432
17287852
|
PCNA
|
PRIM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9660172
2165567
|
H2AX
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
XRCC4
|
CSNK2A1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15385968
5217205
|
TFCP2
|
COIL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
GABARAP
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TERF2IP
|
ORC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16799465
5218770
|
TERF1
|
ORC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16799465
5218770
|
ORC4
|
ORC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
ORC2
|
ORC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
HOXC4
|
SOD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ETS1
|
LCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7970721
|
SPI1
|
VAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11835402
|
ESR1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16144913
|
NR1H4
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21279417
15973435
|
PPARG
|
POU2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12881480
|
PPARG
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18755353
11007963
|
ESR1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16144913
|
THRB
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16260719
|
SPI1
|
CEBPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8695841
22474248
|
POU2F1
|
SPI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16352814
8663022
|
SPI1
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22105598
12032776
|
SPI1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22472882
19423615
|
SPI1
|
SCARB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8007948
|
HIF1A
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19071119
6802010
|
THRB
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16862226
18239067
|
HIF1A
|
NR4A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14729605
|
HIF1A
|
KDM2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32938217
|
HIF1A
|
NKX2-5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21055290
18303027
|
HIF1A
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17426252
23884959
|
HIF1A
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18461556
18381421
|
CSNK2A1
|
HIF1A
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17382325
5219810
|
SENP3
|
HIF1A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7941484
19680224
|
RARA
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11327309
|
ETS1
|
ERG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7731694
|
BMI1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6948569
19233177
|
ESR1
|
BMI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24559156
16582100
|
THRA
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12034878
12218053
|
USF1
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12663664
15563837
|
CEBPA
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1320003
|
CEBPA
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16455820
16774685
|
CEBPA
|
SOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9426001
9013901
|
UBE2I
|
TFCP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
UBE2I
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TFAP2A
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10652362
|
ZRANB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
WWP2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7104155
19343052
|
UBC
|
SENP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7941484
19680224
|
UBC
|
ZRANB1
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
POU2F1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18000219
20215511
|
THRA
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11578528
11687272
|
TFCP2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21655924
19966177
|
ERG
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8388477
22531786
|
AR
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12069693
20610535
|
AR
|
DNM1L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10454563
21724752
|
AR
|
MME
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11162897
|
HSPB1
|
NDN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RARA
|
NR4A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10772826
|
H2AZ1
|
USF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
USF1
|
TRIM25
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9714786
9245730
|
EPAS1
|
KDM2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32938217
|
KDM2B
|
RNF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24457600
17296600
|
USP11
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7998286
20601937
|
ELF3
|
EHF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
17353931
|
IRF2
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9625761
9490737
|
TERF2IP
|
TERF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0605303103
16880378
|
THRA
|
THRB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1782215
17761769
|
PGR
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9052414
|
PRKN
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20098416
|
HDLBP
|
PRKN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GATA4
|
NKX2-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
APEX1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
ATM
|
WRN
|
â—¼ PHOSPHORYLATION
|
|
|
0.8
|
0.8
|
Signor
|
10608806
|
ATM
|
CHEK2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
10973490
|
H3F3A
|
TONSL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CSNK2A1
|
TOP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
1204073
5215931
11244506
|
DDX17
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
17226766
19995069
33742100
20663877
|
EP300
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
18280497
16204234
19622798
12960163
24636898
33742100
|
PARP1
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
19377461
25303530
15808511
|
DDB2
|
HIST1H3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
DOT1L
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
LRRK2
|
ABCE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
ESR1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
BRCA1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
26831064
|
APEX1
|
BAZ1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
28986522
|
ORC2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17525332
25184681
|
LRRK2
|
CHD1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
26496610
|
CHD1L
|
XPC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CHD1L
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19661379
19666485
|
CHD1L
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19661379
19666485
|
ESR1
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33731348
21182205
19805454
20348541
|
ERG
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
28536097
|
EPAS1
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23275444
15261140
22807441
25689462
|
ESR1
|
KAT2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16260778
31527615
|
MDC1
|
DGCR8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34188037
29656893
|
ESR1
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16260778
31527615
|
MYC
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
MYC
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
MYC
|
ILF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
BMI1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20668194
34316702
|
VCAM1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VRK1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
28927264
|
PARP1
|
ZEB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
34462429
|
VCAM1
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
BMI1
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
XRCC5
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12393188
26344197
|
VCAM1
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
SSRP1
|
XPC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RBM39
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28302793
22939629
|
VCAM1
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
XRCC5
|
NAA15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12145306
26496610
|
LRRK2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
CENPA
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
16622419
|
VCAM1
|
ILF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
BMI1
|
ILF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
PPARG
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
32929351
|
LRRK2
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24725412
29519959
|
LRRK2
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
21370995
|
LRRK2
|
SENP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
LRRK2
|
RBM39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
PCGF1
|
BMI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
26687479
|
BMI1
|
BAZ1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26468281
34316702
|
BMI1
|
NCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
ARRB2
|
NAA15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RBM39
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28302793
25277244
|
VCAM1
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
NAA15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
ATM
|
CHEK1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
20068082
|
HOXB7
|
HOXC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
DDB1
|
HIST1H3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
ATM
|
MDC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12607003
|
NBN
|
TERF2IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
ESR1
|
PGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
AIRE
|
H3F3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
AIRE
|
HIST1H3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
ATR
|
WRN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10608806
22159421
17118963
|
BRCA1
|
TERF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34112789
19797051
29656893
|
BRCA1
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34112789
25184681
19797051
29656893
|
BRCA1
|
TONSL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25184681
29656893
|
CHD1L
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
19666485
|
DHX9
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15723802
14704337
21679440
|
DHX9
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12711669
15034300
|
HSPB1
|
HSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25036637
19597476
|
BARD1
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12611903
29656893
|
MYC
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21150319
17314511
29467282
|
RBM14
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11443112
16713569
|
H2AX
|
PPM1G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
18406329
24981860
|
LRRK2
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19826009
31046837
17400507
|
VCAM1
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22623428
33961781
19738201
|
RBM14
|
RBM39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28302793
22939629
26344197
|
H2AX
|
TONSL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
28242625
|
H2AX
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21679440
18406329
20085707
|
SOX2
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21280222
35140242
23667531
|
BMI1
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20668194
24457600
34316702
|
H2AX
|
ILF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
20000738
33961781
26186194
|
NR1H4
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
17333335
25675114
|
SOX2
|
NFIB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
35140242
21532573
28794006
|
EP300
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
H2AFX
|
RNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
ATM
|
NBN
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
10802669
|
CUL7
|
OBSL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CCDC8
|
OBSL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
H2AFY
|
HIST1H3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
ATR
|
CHEK2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
10973490
|
PARP1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
PARP1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
25252691
26831064
|
PRKDC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10608806
25223785
|
WRN
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15995249
17498979
|
ELF3
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
35140242
15075319
|
MYC
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
15071503
28205554
|
MYC
|
TERT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32140074
28628118
28205554
|
PRKDC
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16794079
9398855
21575865
20085707
|
XRCC5
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28415827
21679440
|
TOP1
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15848144
26344197
|
BARD1
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12485996
11927591
|
DERL1
|
CFTR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18555783
16901789
16954204
26618866
|
DGCR8
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24581491
17765891
|
CHD1L
|
RNF146
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
FZR1
|
UBE2S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
H2AFX
|
HIST1H3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
HIST1H3E
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
H2AFX
|
SUPT16H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
HIF1A
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10594042
16189514
|
BRCA1
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15965487
25184681
|
BRCA1
|
WRN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16714450
24709898
29656893
|
OBSL1
|
CUL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21737058
31343991
25752541
21572988
|
DDB1
|
PHF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23238014
29846670
|
SENP3
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
19680224
15632193
22684029
|
ILF2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20808282
30110629
33742100
|
EP300
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20808282
30110629
33742100
|
RNF8
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18001825
23115235
26869104
|
XRCC4
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15520013
9259561
15194694
22939629
9430729
|
CFTR
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
17110338
|
TOP1
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28415827
15848144
|
SUPT16H
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
5218941
16902406
|
XRCC5
|
WRN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10783163
5212534
|
WRN
|
XRCC5
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10783163
5212534
|
CFTR
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
31324722
29924966
|
CFTR
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26627832
17110338
29924966
26618866
23155000
|
CFTR
|
AHSA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
18556464
17110338
|
DHX9
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
H3F3A
|
HIST1H3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
TRIM25
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
NCOA6
|
RARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
BRCA1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
PCNA
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
11601988
10559261
|
ATM
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10608806
10464290
|
BRCA1
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
25184681
10783165
|
LRRK2
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31046837
24725412
|
ESR1
|
MEN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16651450
31527615
|
H2AX
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6805208
18583988
|
H2AX
|
NBN
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
22565321
8391733
|
NBN
|
H2AX
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
22157895
8303386
|
OTUB1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26752685
18954305
|
SSRP1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
34079125
|
PCNA
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20129057
20302655
12930846
21690293
20303835
|
PPM1G
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
27880917
|
PARP1
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
20085707
|
H2AX
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20356835
22184063
26095369
15613478
18406329
14627815
20085707
|
CUL3
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
26949739
|
XRCC5
|
TOP2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12393188
20085707
|
SPI1
|
CEBPA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16983342
12091339
|
ESR1
|
DNM1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19805454
21217774
|
ESR1
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9717844
25303530
25604459
|
CHEK1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
PCNA
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
HIST1H3E
|
SUPT16H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
POU2F1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
H2AFX
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
BAX
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ATM
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16858402
27918549
22184063
9488723
32518374
20081839
18344987
21676867
22451927
21704408
11571274
11893489
26095369
|
DDB2
|
XPC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22039351
23319653
28760956
27203177
29604309
15882621
|
DHX9
|
ILF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22863883
22939629
23986595
|
MYC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15616592
16287840
32140074
16126174
17157259
12776737
|
GATA4
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18252717
27208796
11481322
|
BARD1
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16391231
11498787
|
MYC
|
RBM39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
30415952
29467282
|
MYC
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17314511
20195357
30415952
29467282
|
MYC
|
UBC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
16996503
19131971
|
NCOA6
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10823961
12519782
|
XPC
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
28760956
|
HDGF
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21907836
34079125
|
CENPA
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
16622419
34079125
|
WRN
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20802463
15733840
|
XPC
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
19805520
33961781
28242625
|
TERF2
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21824286
21044950
22157895
|
CBL
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
PRKDC
|
XRCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
PCNA
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CHAF1A
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ATR
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
DCLRE1C
|
PRKDC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CHD1L
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EP300
|
PPARG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
NCOA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
DDB1
|
KAT2A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11564863
21987584
|
NBN
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21108945
16051665
|
RBM14
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11443112
33742100
16713569
|
NCOA6
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15604093
19596656
24368734
10788465
11877444
19047629
|
ERG
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24591637
21575865
|
WRN
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14734561
14596914
|
WRN
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11889123
10608806
|
PRKDC
|
ERG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24591637
21575865
|
TONSL
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
21113133
25184681
21055985
33961781
|
ESR1
|
BTF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31527615
18025262
|
DDB2
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
AR
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
PARP1
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
H2AFX
|
PRKDC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
XRCC5
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
EP300
|
YY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
ATM
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
KAT2A
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
AR
|
KLK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CBL
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
H2AFX
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
DNM1L
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
MDC1
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29656893
14519663
28943310
12607005
26734725
18006705
|
ATR
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17526493
10608806
15758953
23368512
|
VDAC1
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9843949
16189514
15637055
28760928
12767928
|
NBN
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10426999
18171670
19244116
12124328
10783165
25659039
25184681
25939603
11504724
29656893
|
MDC1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21622030
19766185
15569676
12611903
17525332
12607005
29656893
|
CHD1L
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
19666485
33053171
22146311
34079125
23926104
19661379
|
EP300
|
NR4A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21988832
12082103
16713569
20438716
|
MYC
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17353931
17314511
29467282
|
TERF2
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22939629
19287395
10888888
|
RARA
|
NCOA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10823961
16713569
10866662
11158331
10567404
|
NCOA6
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10866662
16794079
10567404
10681503
11773444
26487511
|
H2AX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16377563
20000738
27728808
33961781
28796254
18406329
28242625
16522924
20085707
|
ILF2
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20808282
17389650
9442054
|
WRN
|
TERF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12181313
18212065
|
WRN
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12177300
11328876
26496610
14734561
12937274
21679440
10880505
10783163
|
UHRF2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21952639
28951215
27114453
|
TERF2
|
ORC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16799465
18761675
|
PCGF1
|
KDM2B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16943429
26687479
25533466
27505670
23395003
29985131
32628469
27705803
22325352
33961781
29502955
24981860
|
CBL
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
ATM
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
H2AFY
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
IFFO1
|
XRCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
UBC
|
WWP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
HIF1A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
EP300
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14633989
20856196
20808282
30110629
19934257
|
USF1
|
APEX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9506886
7534297
|
TERF1
|
ATM
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18160036
11375976
15314656
|
ATM
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
29656893
10783165
11016625
10866324
10550055
15713674
18344987
10608806
17478428
|
ATM
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24800743
10783165
25088203
11252893
30952868
10608806
17507690
22464731
25895060
10839545
15758953
10839544
|
ATR
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
23901102
29656893
16713569
11016625
10608806
17478428
|
CHEK1
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15190204
10859164
11390642
|
ATR
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21872579
18583959
|
ETS1
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17213822
|
H2AX
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12485996
34321665
19766185
18001824
31501894
11927591
18344987
20681793
26095369
18001825
29499138
19805520
26121674
10959836
12419185
|
ESR1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
1244506
11782371
15674350
29367421
27977889
17392432
16860316
10334989
16260778
11244506
16061635
12400015
17505062
20060929
25499220
16713569
31527615
11493692
|
EP300
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21102443
19887647
10655477
11782371
16713569
21212407
22787115
|
MYC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12646176
11916966
16713569
20215511
9788437
30415952
14612409
|
DHX9
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9662397
26831064
16713569
12592385
|
BRCA1
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16260778
25184681
11498787
10783165
|
CBL
|
FLT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17635922
10514377
19276253
|
CHEK2
|
TERF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
26799419
19375317
|
DDB1
|
DDB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
22118460
28035050
12050362
24249678
26410533
22822215
28416769
29262658
16473935
18593899
30923324
16678110
16964240
20368362
12812979
19295130
16751180
19109893
17360488
16260596
27203177
17392787
10777491
12151405
32985517
14751237
22039351
17041588
12732143
11564863
9418871
19966799
33961781
26186194
34251884
16949367
|
DHX9
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20385589
17498979
|
EP300
|
KAT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23667505
23555303
21559432
|
EP300
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11268218
16713569
18263614
12937166
24939902
14988403
33742100
|
EP300
|
PPARG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500849
17468099
10944516
14701856
11287611
19596656
32603375
11877444
12040021
10075656
30595551
22787115
12479814
|
EP300
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
11782371
12738788
25728767
11867769
12479814
23065768
15308690
20388208
14761960
22227247
8799122
20348541
23403292
12714702
11581164
16713569
19838210
18765668
16645043
30418174
12574227
|
YY1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
YY1
|
HSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
HSF1
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12919958
9325337
|
KAT2A
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16287840
28628118
10611234
32140074
20691906
35140242
12660246
28205554
17967894
|
RNF8
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25512560
28943310
24240613
18001825
26734725
18001824
18006705
|
MDC1
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21622030
16377563
19234442
28242625
32518374
20159462
21676867
12475977
14519663
15201865
12607005
21293379
30598506
18001825
29499138
26734725
18001824
18583988
|
MDC1
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15377652
30179224
12607003
18678890
29656893
27590578
25064736
20460517
19804756
23115235
14519663
15201865
12607005
20224574
18001824
18583988
|
MYC
|
MEN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
BIN1
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15992821
31815296
30253944
11306501
10380878
|
YY1
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
18490439
19219071
2191300
|
TFAP2A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9632747
8276360
7555706
|
NDN
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26384308
24349431
|
MYC
|
BIN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21447800
10380878
18348166
|
MYC
|
POLE3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
16403426
|
MYC
|
GOLPH3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
PRKDC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
YBX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12080043
18414489
|
MYC
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
IRF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
TOP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
PRKN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20638938
15078880
23277542
|
MYC
|
RBM39
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
SMARCAD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
CEBPA
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12873812
|
MYC
|
CEBPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12873812
|
NBN
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11110662
18583988
15733840
16377563
31501894
20081839
23145133
22157895
22941933
21676867
16932743
15201865
18001825
18001824
12419185
|
NCOA6
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14645241
|
H2AX
|
OTUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TOP1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
34079125
15247263
15848144
|
PARP1
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24140708
16490787
21575865
16794079
14734561
21679440
34079125
10400681
17283121
20085707
|
ETS1
|
PARP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10435618
11973649
24448423
|
PNKP
|
XRCC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15385968
28514442
32296183
17353931
21637298
33961781
26186194
|
POLA1
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10882098
10757793
12045100
|
PRIM1
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10882098
10757793
12045100
|
XRCC5
|
PRKDC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15941674
10750018
20023628
17308091
15758953
20085707
33005030
10446239
26496610
19303849
20711232
9312071
26446488
15520013
28154079
28345663
16857680
12393188
22404984
21679440
26344197
|
PRKDC
|
PDX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16166097
|
PRKDC
|
VCP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16140914
|
SMARCAD1
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21549307
18675275
|
TERT
|
TCF7L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19571879
11532957
21654818
|
ETS1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16556873
20842112
|
VCP
|
DERL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
15215856
|
COIL
|
VRK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26068304
21920476
34079125
|
WRN
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
10871373
12750383
12633936
20600238
|
PPARG
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17389773
14764597
19673929
|
IFFO1
|
XRCC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
16713569
33961781
31548606
26186194
|
ESR1
|
BARD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17275994
|
SPI1
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11835402
19747912
|
ZEB1
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21791114
18381457
17615296
|
ZEB1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19921427
22391641
|
FN1
|
ITGA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
20644254
22067905
24202395
|
TERF2
|
ORC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16799465
31160578
18761675
|
HIF1A
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18461556
19490906
11879638
|
PPARG
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22472882
20234816
21159608
|
SPI1
|
MME
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15892171
20947507
|
AR
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18794357
20610535
|
LRRK2
|
DNM1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22228096
22639965
24282027
29541021
23813973
|
ROCK1
|
DNM1L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
31063459
22326220
29654945
|
TFAP2A
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1945412
8247540
|
ETS1
|
CSNK2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10849443
19027835
|
TFCP2
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21361876
25609232
|
PGR
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19211567
17717077
17020914
|
UBE2I
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22713328
19995069
25114211
|
RBM39
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21182205
33731348
11704680
15694343
|
ESR1
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20663877
19995069
25604459
12738788
11250900
21182205
20348541
|
TFAP2A
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10497269
19458056
9850080
|
ESR1
|
H2AZ1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19515975
23108396
20023423
|
ESR1
|
NFIB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26153859
18414489
|
AR
|
MME
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
11162897
16949732
|
AR
|
TCF7L2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12799378
20610535
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
THRA
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15650024
|
RARA
|
THRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15650024
|
USF1
|
HOXB7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1677811
12697323
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
VCP
|
DERL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
15215856
|
H2AFX
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
ATR
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
POLE3
|
SMARCA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
CSNK2A1
|
SUPT16H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
CSNK2A1
|
SSRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
WRN
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
KDM2B
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
ATM
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
MDC1
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
H2AX
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
28514442
33961781
24981860
18406329
16522924
|
TOP1
|
TOP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
ATR
|
CHEK1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
15775976
|
PCGF1
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
RAD23A
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.93
|
STRING
|
36370105
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
UBC
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
IKBKG
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ORC1
|
ORC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
RNF2
|
PCGF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
24981860
|
PCNA
|
POLR2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
PCNA
|
POLR2E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
OTUB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
PCNA
|
UHRF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
CHEK1
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
CHRAC1
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
CBL
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
7721825
8621719
8900205
8626543
9178909
16107303
11741956
11904433
|
CHRAC1
|
SMARCA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
TOP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
HIF1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17382325
5219810
|
ORC4
|
ORC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15232106
12614612
15910003
18234858
|
ORC6
|
ORC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15910003
28514442
11323433
12614612
16549788
33961781
26186194
12004060
|
RNF2
|
BMI1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
16710298
5218667
|
ORC1
|
ORC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
12614612
26496610
16549788
14681455
31160578
17716973
|
BIN1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
ATM
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
DHX9
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12431996
17525341
29367421
27977889
19916563
12732733
10477523
20060929
23680151
8944023
22110403
12951069
23086937
14638690
27239795
29355525
9788437
11925436
11257228
24289923
14647430
19176389
15184379
9738006
16403807
29180510
11278247
33589814
15265711
15159397
34408138
16713569
19117993
20681793
16391231
11301010
16489000
23416467
17664283
15569676
29858377
19369211
18493658
29656893
20351172
28398198
12485996
32347575
19766185
14636569
10026184
12700228
31270457
11573085
11526114
24085845
25823446
33961781
32092106
18936166
28514442
20215511
25184681
26490435
28948225
12890688
12438698
28262780
26831064
9342365
10635334
15855157
11504724
11773071
25252691
9798686
26350354
21901007
24695549
12887909
17873885
11498787
27454289
11927591
24981860
25652403
25634209
|
HIF1A
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15280364
19589782
16543236
11823643
22807441
19666581
16189267
18047470
15342390
12042299
19680224
22735262
23448368
26135796
23618863
14691445
19696166
11959990
27320910
16847340
24821806
22789427
17906695
8917528
20620956
20000859
15261140
16081065
12778114
22219185
15154850
25192544
22075993
19071119
22908229
19940151
21187066
24421387
23880760
11940656
23966271
26826385
26944191
12588875
23746844
11063749
27808477
19074848
20603618
15155277
18268343
20829524
21148070
12914934
17502379
22684029
17382325
26751287
|
NBN
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20224574
7891431
|
H2AX
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6805208
18583988
|
MSH6
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
16189514
15225546
24958773
21725088
26496610
11005803
11274057
22939629
22232658
26344197
|
PCNA
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
12192049
22939629
9649448
15225546
24958773
12045192
26496610
10353443
8861969
30301766
9092549
8999859
12400013
26344197
|
ORC1
|
ORC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15232106
16189514
20850016
12614612
11931757
26496610
16549788
14681455
22398447
31160578
11323433
11779870
17716973
|
TERF2IP
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
8286516
21829167
|
BAZ1A
|
SMARCA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
NBN
|
TERF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
SMARCAD1
|
TRIM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
MSH6
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
UBC
|
UBE2S
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
ATR
|
CHEK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
DERL1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
UBC
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
KDM2B
|
PCGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
TERF2
|
TERF2IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
PRKDC
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ORC4
|
ORC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
15232106
9353276
16189514
15910003
20850016
31467278
12614612
16549788
31160578
11395502
11323433
12004060
17716973
|
ORC4
|
ORC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
ORC2
|
ORC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RAD23A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PARK2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
POLR2D
|
POLR2E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
UBC
|
UCHL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ORC1
|
ORC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EP300
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
SSRP1
|
SUPT16H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ORC1
|
ORC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ORC2
|
ORC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2A
|
POLR2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
AR
|
ABCE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
PARP1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
17548475
11440997
12727891
15135726
10364231
11340072
9804757
|
PCNA
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
MYC
|
APEX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14519204
11983916
12695333
11085504
|
EP300
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14633989
20856196
20711647
|
CSNK2A1
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20955519
20507565
10023679
19118383
21576760
18583988
15066279
20471329
21592330
9407949
21118972
20533398
|
GZMA
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12524539
12555094
|
WRN
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
H2AX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11934988
15279782
12792649
11893489
10959836
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
XRCC5
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
H2AFX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
WRN
|
ATM
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
H2AFX
|
ATM
|
â—¼ SHARES_COMPLEX
|
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
MDC1
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
H2AFX
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
CHEK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
ATM
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
TERF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11331603
11877377
12607003
15140942
15459660
15964794
16163361
17303408
22266654
22634377
23847781
|
MSH6
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
H2AFX
|
ATM
|
â—¼ REGULATES
|
✅
|
|
105.0
|
1.0
|
ACSN
|
11283614
11331603
11571274
11850621
11877377
12086603
12202749
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15211575
15242590
15279786
15375219
15377654
15385537
15459660
15485915
15496928
15498778
15549137
15655342
15798197
15964794
16163361
16332722
16449207
16531125
16713580
16805667
16818604
16858402
17055429
17102137
17116323
17116885
17296725
17303408
17384638
17582221
17660363
17965729
18001824
18001825
18006705
18087292
18171670
18171986
18212739
18398454
18469862
18524993
18543256
18558713
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19202191
19217833
19270065
19282663
19342888
19362533
19490890
19622404
19654615
19686080
19772495
19793801
19892829
20021983
20027199
20051983
20064462
20160076
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23030059
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
7575488
9407949
9488723
9721205
|
ATM
|
MDC1
|
â—¼ REGULATES
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATR
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15510216
10608806
17478428
17124492
|
ATM
|
DCLRE1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15723659
25842165
15574327
15456891
16874298
15468306
|
ATM
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
27245613
24681585
21095578
18971907
21095582
27027353
23573973
27068951
25956861
23707302
26942179
|
ATM
|
TERF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16223874
17525332
15314656
|
ATM
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20471956
15494392
15140942
29590107
26170237
21108945
15838517
27220480
|
ATM
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
27486774
21490922
20932476
20188669
18583959
22435563
28626800
24957606
16497931
21872579
20932475
19917246
16965765
23063077
|
ATM
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
12433983
12861053
17485521
23146902
10839545
19413330
15302935
27602502
17429352
19523210
24360018
20068231
17507690
17570479
10608806
12598907
18669648
25088203
18003706
11252893
17431132
23097684
10766245
12814430
10802669
21664921
26512707
10839544
11927276
21130714
17525332
12447395
14707289
15733840
15279770
25119968
18644472
28822740
|
ATM
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
176.0
|
1.0
|
Omnipath
|
26683224
17303408
28852018
10713094
20080130
27545311
9488723
15342622
23941746
26485758
28937603
15279786
24882580
10744722
15125777
25746763
18583988
28051860
17570479
16531125
21329876
23892398
19607708
16940182
26643553
20396397
28259974
25361978
17660363
15459660
19375317
25247188
16311512
23118481
20498628
22030216
25613496
22420423
9407949
17918214
12493754
20859824
26158765
15700044
27558808
11901158
27602502
20637859
16163361
20599567
23638118
16481012
12242661
23847781
12024051
15140942
11728459
12454775
16936775
25450480
28950914
26295265
20160490
22319212
24349411
18006705
20723763
18678890
12805407
20860841
23386996
24050180
11668173
27271602
29304495
12447382
24798733
9889122
23347679
18794134
21147465
21421565
26516160
17715138
21376743
19440053
12773400
10973490
17174984
26442630
15694385
11877377
29022904
18809224
11850621
18787700
12718885
19481982
22743550
20372057
15212693
16085488
19101576
29555944
25954303
24473398
18087292
16794575
24492479
24244353
19793801
25404613
21102523
29156743
23253087
16997395
7575488
25808488
20647331
18584027
21851590
21315088
23705030
15629715
29741650
21772273
11025670
18590585
26610585
15964794
29434792
20068082
23006513
19881958
19230643
12607003
24769180
25249630
15024084
19772495
25714019
18603484
25173936
23666059
19473886
27568553
22808196
|
ATM
|
PPM1G
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26324325
17525332
|
ATM
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
17189255
12231622
17303408
24492479
10464290
22230547
15677476
16822724
28985363
29088817
16163361
32868446
19549901
25818648
22923485
19103741
17570479
27939942
19808981
23847781
22355272
24714417
15964794
21376743
31983282
25224041
16908529
12607003
19244120
17525332
15459660
34249431
28107384
12186630
25714019
11877377
26553138
27568553
19535303
15507430
26578593
|
ATM
|
TERF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
17717821
15314656
17570479
23732473
26586433
11375976
22266654
|
ATM
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
69.0
|
1.0
|
Omnipath
|
29774099
20976184
26683224
25663895
12676583
17303408
14657349
29167438
27545311
10859164
19056039
15485915
28808226
12588868
16163361
15650047
12676962
17570479
14988723
14681223
26516160
10608806
26069190
29741650
12676925
23847781
17118344
11252893
20376879
15964794
15149599
18691976
19059218
20068082
15707391
12607003
25450480
17525332
11553781
19646247
15870257
15459660
20798862
19716789
11877377
12660173
11390642
15674326
16782033
28396830
28228262
12446774
15533933
15212693
29555944
|
ATM
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
197.0
|
1.0
|
Omnipath
|
27410735
28544233
16426903
28797244
9488723
23847653
30197789
21930799
18158901
21693595
18848500
22819196
15603757
16760673
17570479
24688021
24793032
27458206
16531125
22028490
30154456
19230794
23202908
25852739
19059218
26073471
22247744
28259974
29584802
25691887
19049966
20368801
26700820
29386061
28124509
20613862
27550454
20847938
27388041
27752097
23269287
24480460
22237206
20461094
20971043
26941327
18285803
21690091
15279774
23891287
25847270
24490130
25349305
26906421
20637859
26314960
15286739
27780918
20454618
30013081
28671946
25218945
23742011
26391293
23972723
23382699
26416514
27442013
20703100
24726884
26512707
27332952
29641431
25287622
26295265
14643438
29163809
25264544
19895790
26504743
26113859
27431324
28790385
18413980
21283714
21787120
20205745
19781914
25093845
27135971
23227178
22224778
20923785
20860841
24244154
23386996
30065307
16858402
11879731
28009280
23343929
20192759
22761798
26855420
24378750
20068231
20580718
14504478
24893124
29048667
25661368
26860083
26019182
20488183
28764946
22205726
23977391
18471973
19591958
28239143
20542002
17525332
20495376
18755145
23050241
17782711
11571274
19473884
28431265
25742493
18248856
17690115
20684759
26317467
21727091
24651472
25827888
27164092
28587922
20976184
30723510
20471486
23772364
29794999
11893489
19014481
20165693
26671524
16997395
20936109
26114388
23845989
15138496
22761813
23355489
27455285
28943310
21348461
19647519
23678292
23166506
28099474
29434792
25249630
25269479
27310012
15177039
22559321
26045162
20865059
22972376
21148072
26760771
21188122
22962268
22768044
26711340
20460517
27845910
28855246
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
ATM
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
73.0
|
1.0
|
Omnipath
|
25128619
22496453
34194047
30323812
26158765
16862143
28607002
19584288
20858735
28851455
18285803
34419074
17833484
22491012
25404613
21642969
28439615
27364555
27602502
26671524
23096706
23935532
28739276
24754998
25905708
28847822
24461736
23318425
23346550
17178852
27432546
27820601
17942393
21868291
32060145
22205726
25846574
26293668
25533843
23034801
23352131
28249048
23633913
17525332
18657500
24794298
23645696
26212333
23050241
22715096
27376578
23370278
24657165
29540829
25173936
19071136
28847828
20424263
34518220
25956864
23554604
|
ATM
|
PNKP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23042680
23449221
24000320
21824916
23433795
17525332
|
ATM
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
28193847
21705321
22234877
12607003
12607005
22234878
17525332
18006705
|
PCNA
|
ATR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
PCNA
|
ATR
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
CHEK1
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
MSH6
|
ATR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
ATR
|
CHEK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15485915
15703371
15798197
16530042
16697054
16713580
16805667
16880517
16885023
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18931676
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
19686080
1974050
19793801
19847258
20051983
22021614
23414611
|
ATR
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
H2AFX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
42.0
|
1.0
|
ACSN
|
11438669
11877377
14988723
15136767
15459660
15485915
15798197
15867354
16332722
16540648
16713580
16731533
16885023
17102137
17116885
17296725
17303408
17384638
17582221
18048416
18511906
18543256
18677104
18716619
18756267
18931676
18995830
19004803
19282663
19357644
19490890
19622404
19686080
19772495
19788416
19793801
19793861
19841479
20019063
20051983
9488723
9858600
|
ATR
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
26927092
17478428
24746700
15159397
17531442
10866324
18677104
19622404
15798197
19793801
20860841
16713569
11114888
23422745
20936109
16322207
19282663
20068231
17116885
17582221
25879655
10608806
17384638
23346553
12773400
12183412
17525332
15459660
11278964
17296725
11877377
17102137
10550055
16522651
|
ATR
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
21722802
20859824
26683224
18677104
19622404
15798197
19793801
27545311
23137030
19836377
20647331
20599567
19282663
19658174
17116885
16481012
17582221
11715017
17384638
29741650
12024051
18802408
10973490
9857181
26442630
15459660
17296725
11877377
17102137
12493754
|
ATR
|
PRKDC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12186630
22592045
22057367
24500207
18077418
16908529
15507430
29309644
|
ATR
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
20461094
20976184
20471486
22224778
17303408
28797244
18677104
19622404
15798197
19793801
9488723
20860841
12919958
18158901
20165693
20936109
22002605
26114388
29114052
21283714
22819196
19282663
24893124
17116885
22531632
17582221
30013081
25438756
26019182
17384638
19647519
20205745
23166506
25852739
18471973
27442013
22247744
29584802
20542002
19875294
25249630
20368801
15459660
27332952
27715493
19772495
25247188
17296725
11877377
14643438
24813610
20613862
17102137
20847938
21148072
23443128
27431324
29163782
23754961
17690115
15975956
18663141
21787120
22545090
27077811
19781914
27164092
|
ATR
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17715134
15758953
17526493
18077418
|
ATR
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
232.0
|
1.0
|
Omnipath
|
29774099
26683224
26658951
28180282
27545311
29605721
16461339
26165835
24971543
28937603
28573382
27713304
27643582
18723495
26082189
25205668
29088070
22971344
20536192
22353182
28051860
19276361
14681223
14988723
26069190
23892398
12676925
11252893
26643553
16520097
23383325
20396397
16431910
19059218
21440578
22357623
24753408
28572758
11090622
25795119
29309644
15870257
34398682
19716789
23508805
25965828
24947324
23380594
19071136
23118481
28396830
15533933
15190204
19737971
24023735
27283761
28025997
23696651
16360315
28915668
15707569
19062161
14657349
19489726
21937510
25448276
26721387
27558808
25104095
19056039
23468519
17081992
20679434
20062519
28808226
27679857
12588868
22203733
29928473
25459351
28558031
12766152
26748709
28986587
18265945
18669648
27775084
18691976
12781359
23583268
29221122
26633513
34509474
22564734
31928997
33863777
27685627
27167194
29118324
30796221
24366029
11390642
21907702
24632611
27068998
24349411
31591366
17686975
15665856
19781914
21736880
12676583
27690219
23386996
21482692
24113549
21730979
15775976
15272308
17851138
33811702
27271602
30510197
28273450
29209046
23849791
18794134
25024738
12676962
26438152
20932473
15279789
20376879
16414131
15149599
24387336
18790091
24327542
17525332
19646247
23997120
20798862
29022904
15674326
24500207
16137618
12446774
16885021
20639859
19101576
20976184
25663895
24244353
27603133
10859164
23333305
24621867
22863316
24072747
15650047
22084686
10859163
21851590
23613359
15629715
29741650
17118344
22706734
25565400
25301724
17327276
23006513
29242514
24906880
15707391
27908669
18353973
27708213
18243098
18603484
12660173
18955550
26039276
19473886
28255082
25898113
29163782
16629900
25937999
30100999
24140082
24970150
22084169
|
HIF1A
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18366759
17558861
15706354
24349374
|
MYC
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8845569
11103792
12695333
|
BAX
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16189514
10365962
9843949
12767928
|
NBN
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PCNA
|
BRCA1
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
H2AFX
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
CHEK2
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11438669
15459660
15810020
15867354
17296736
17464182
17568790
18048416
18566216
18756267
18931676
18971944
19686080
19788416
20019063
20126263
|
BRCA1
|
XPC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
BRCA1
|
DDB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
MDC1
|
BRCA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
17303408
17660363
18001824
18006705
18087291
18583988
18590585
18678890
7575488
9407949
|
BRCA1
|
CHEK1
|
â—¼ REGULATES
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
MYC
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12032322
19882681
20940401
10375022
21668996
11916966
12646176
11983916
|
BARD1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
99.0
|
1.0
|
Omnipath
|
16403807
16391231
28262780
15159397
25652403
26350354
26490435
14647430
11927591
25184681
16713569
11526114
35203293
9738006
12732733
24289923
11573085
18936166
23086937
24085845
12890688
15855157
24695549
19369211
9798686
11257228
11498787
12700228
11925436
10477523
19176389
23680151
25634209
23416467
34726323
29355525
18369654
14636569
11504724
12951069
19117993
20060929
17873885
14638690
18493658
11278247
15184379
22110403
11301010
11773071
12431996
10635334
20029420
9788437
17664283
21901007
25252691
12485996
10026184
12438698
17525341
16489000
8944023
15265711
12419249
20681793
9342365
27239795
20215511
25823446
19916563
|
CHEK2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
18566216
15810020
24492479
20860841
16713569
26383678
10724175
12049740
24986639
23388117
14701743
30327455
33397362
22921572
18804494
24348208
20364141
22941656
15459660
17464182
20952512
24069304
15485917
22193408
12111733
27170701
|
MDC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18087291
17525332
12607005
|
BRCA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11085509
16713569
11016951
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
BRCA1
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18001824
18001825
17145710
12419185
|
CBL
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11353765
15169881
18835194
20189481
|
VAV1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19635790
20940296
16289966
23331499
16356860
11133830
23180781
11331248
12881521
18835194
9200440
16713569
11313921
|
LCK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
9525940
10829062
10799548
10934191
7721825
16107303
12604776
9890970
17570479
11904433
9178909
10092522
11997497
12522270
8621719
9102067
11239464
11994282
11741956
|
PARP1
|
CHD1L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22146311
19666485
|
PCNA
|
CHEK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
PCNA
|
CHEK1
|
â—¼ SHARES_COMPLEX
|
|
|
47.0
|
1.0
|
ACSN
|
11756412
11877377
12086603
12466554
12766152
12875843
14624239
14657033
14726013
14988723
15136767
15175241
15189446
15459660
15703371
15798197
16697054
16713580
16805667
16880517
16934469
17035102
17102137
17116885
17141802
17296725
17303408
17384638
17582221
18157158
18451105
18469862
18677104
18995830
19158510
19217833
19225445
19258535
19282663
19342888
19622404
1974050
19793801
19847258
20051983
22021614
23414611
|
CHEK2
|
CHEK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26516160
24804719
26437226
29555944
|
H2AFX
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
CHEK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
12607004
18087292
17303408
20723763
18678890
19793801
9488723
12919958
24050180
15279786
7575488
16163361
18584027
18583988
22743550
16531125
23847781
18590585
15964794
21376743
12551934
12607003
17660363
15459660
19772495
11877377
18809224
11850621
9407949
18006705
|
NBN
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
18087292
17303408
20723763
18678890
19793801
9488723
11438675
24050180
15279786
7575488
16163361
18584027
18583988
22743550
16531125
23847781
18590585
15140942
15964794
21376743
12773400
10973490
12607003
17660363
15459660
15024084
19772495
11877377
18809224
11850621
9407949
18006705
|
PRKDC
|
CHEK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
77.0
|
1.0
|
Omnipath
|
31959038
12607004
22669845
18948271
16794575
24492479
15829965
23684611
12805407
20406977
26929199
21482692
27818175
20660628
33870196
11668173
21731742
33879618
15618221
11901158
24421316
21099343
12386164
15096610
24415760
12447382
12855706
15213307
16150728
20599567
16024600
17570479
12447371
28750002
34244606
33901880
15367709
26505995
16940182
33747205
11025670
12024051
24844881
15668230
10973490
20713355
33961649
19151762
16936775
16798742
12607003
30001349
18644861
25361978
20305300
11390408
20501833
15361851
16982735
23380594
15674326
17237275
20160490
20498628
33851958
15282313
25550082
31609975
15975956
11085506
12493754
|
XRCC5
|
DCLRE1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11955432
16600297
16093244
16914548
|
XRCC4
|
DCLRE1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
Reactome
|
16439204
17470781
22529269
15451442
14561766
12077346
10757784
9259561
16439205
11702069
18046455
9430729
12509254
|
PRKDC
|
DCLRE1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17242184
15723659
11955432
16600297
23163657
22529269
16874298
21641068
19423708
15936993
1660029
|
PCNA
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
DDB1
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
DDB1
|
DDB2
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19440234
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
DDB2
|
DDB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
54.0
|
1.0
|
Omnipath
|
9418871
17145710
16751180
27203177
22118460
17041588
20368362
18593899
16964240
12050362
19295130
22039351
11564863
16473935
16678110
17392787
24249678
19109893
12151405
26186194
12812979
16949367
18936169
22822215
14751237
10777491
26410533
16260596
19966799
17360488
12732143
|
DDB2
|
XPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15882621
22039351
19740755
29604309
23319653
|
PCNA
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18263614
11268218
16713569
|
SENP3
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15632193
19680224
|
EP300
|
NR4A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21988832
20438716
12082103
16713569
|
EP300
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11971970
10779504
24480624
17011549
16713569
|
EP300
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20471956
16051665
21108945
|
EP300
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
24821806
12573436
17145710
16847340
12588875
19589782
11940656
25192544
11959990
18519678
23448368
22219185
11823643
12042299
15342390
23746844
19071119
19680224
27808477
15154850
19696166
8917528
17906695
18268343
22735262
21148070
15261140
19940151
23880760
22807441
35430356
14691445
12914934
20000859
12778114
26751287
16081065
22789427
16543236
24421387
17382325
17502379
22684029
21187066
19074848
23618863
23966271
20603618
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
EP300
|
YY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11486036
7758944
18542060
9199306
17510411
|
CSNK2A1
|
HSF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12659875
15302935
|
KAT2A
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11804596
19407812
15522869
12660246
|
PARP1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
WRN
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
11283614
11900249
12202749
12648680
14726013
15385537
15703371
16449207
16697054
17055429
17116323
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19362533
19490890
19809470
19847258
20027199
20056333
20064462
20211143
20691907
20713526
21376743
2191300
22657828
22743550
23082994
23161013
23253856
24036544
24050180
24709898
|
WRN
|
LIG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
11283614
11900249
12202749
12648680
14726013
15385537
15703371
16449207
16697054
17055429
17116323
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19362533
19490890
19809470
19847258
20027199
20056333
20064462
20211143
20691907
20713526
21376743
2191300
22657828
22743550
23082994
23161013
23253856
24036544
24050180
24709898
|
PARP1
|
LIG3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
ESR1
|
MACROD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17893710
18206366
19403568
15691879
|
XRCC5
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
H2AFX
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
RNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001824
18001825
18006705
18087291
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
H2AFX
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
RNF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001824
18001825
18006705
18087291
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
H2AFX
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
81.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15496928
15549137
15655342
15798197
15964794
16049003
16163361
16332722
16377563
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17349954
17384638
17582221
17660363
18001825
18006705
18087292
18171670
18212739
18469862
18543256
18583988
18584027
18590585
18678709
18678890
18809224
18995830
19151707
19217833
19270065
19282663
19342888
19490890
19622404
19686080
19772495
19793801
19793861
19793862
19841479
20021983
20051983
20064462
20101220
20118229
20723763
21376743
22743550
22771115
23847781
24050180
7575488
9407949
9488723
|
MDC1
|
RNF8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001824
18001825
18006705
18087291
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
CSNK2A1
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20711462
20507565
19118383
18411308
21576760
18678890
18583988
15066279
20471329
19230643
21592330
21118972
18006705
20533398
|
H2AX
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
21676867
14519663
18001824
21293379
16427009
16377563
18583988
21622030
18001825
12607005
19234442
20159462
15201865
|
MDC1
|
RNF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
24240613
18001824
25512560
18001825
18678647
18082599
18006705
|
MDC1
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17145710
15201865
20460517
23115235
14519663
18001824
18678890
19804756
18583988
19230643
12607003
12607005
20224574
|
MEN1
|
CDH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19737400
9694656
10473551
19079338
|
PCNA
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
20713735
20154325
22118461
11274057
11441019
11005803
18326858
17984070
11809883
16188885
16143102
|
MYC
|
PPARG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
MYC
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
MYC
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
TCF7L2
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
12095419
19561604
19895682
15579438
26947016
16204248
12799378
12907606
17360646
9727977
21533051
20133699
15576399
19784072
24447505
12591729
20818421
18852287
11973610
|
PGR
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8701093
9408078
22396492
9305935
22892083
10651641
|
HIF1A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20404562
23059786
19845622
18616527
15780936
21303984
|
PPARG
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11973610
17462534
16405739
19075513
|
YY1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
9797456
16314465
10528225
8266081
19279113
17287852
10713181
18490439
17434929
16878156
18542060
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
15681429
17082780
7556187
8076602
20097210
12695333
15867211
19259613
|
MYC
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9632747
19176757
23364919
10523846
|
MYC
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7597041
18358094
22911891
18809243
1280813111085504
11085504
|
MYC
|
H2AZ1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18414489
22055461
12695333
11085504
|
MYC
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14519204
11896591
8376401
10421838
|
MYC
|
PARP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23277454
12695333
|
MYC
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
76.0
|
1.0
|
Omnipath
|
16287840
15655249
12821782
16880523
21807113
19047367
14744757
16489011
12941894
10786671
14519204
19360348
10723141
12970752
15595642
18365874
15665468
22207128
14611815
10022128
15226182
11274400
10491298
11606399
17070091
19787269
19806010
20454512
19762557
21132266
21553143
18818322
10914736
17934056
19148473
11435602
12695333
12802280
21995449
11287602
12044867
21627565
23860446
17942561
19649288
23759068
10606235
12807729
15958520
17141225
20723213
16402390
16785237
18093727
21855630
24705139
18367227
14563552
16205635
19003324
9988278
17706770
17967894
18226852
18754863
10637317
18586674
14612409
19912441
15371341
11916966
12646176
11279234
18158869
|
YY1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8266081
15805285
18490439
19219071
2191300
|
TCF7L2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17306568
17666529
23343194
21285352
15576399
21151179
22761862
22290435
16039586
19619488
19623618
17143292
|
NBN
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
NBN
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12607003
14726013
15175241
15459660
15703371
16581787
16697054
17088286
17116881
17303408
17713585
19208614
19364882
19772495
19847258
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9488723
|
PARP1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
H2AFX
|
â—¼ PROTEIN_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12607003
14726013
15175241
15459660
15703371
16581787
16697054
17088286
17116881
17303408
17713585
19208614
19364882
19772495
19847258
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9488723
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
WRN
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
WRN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
TOP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
20875401
15911331
15848144
14699148
15247263
|
PARP1
|
POLA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9563011
9518481
|
PARP1
|
SUPT16H
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18406329
16682447
|
XRCC4
|
PNKP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17145710
21637298
26186194
17353931
12032095
32296183
15385968
|
PRKDC
|
PNKP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23433795
21824916
24000320
|
PRKDC
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
29043077
11889123
17570479
20516064
24429382
18157161
|
PRKDC
|
GOLPH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
28213314
25691054
25550082
24485452
25634214
|
PRKDC
|
POU2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17213819
9368058
14612514
|
PRKDC
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19444312
27432546
23370278
|
PRKDC
|
USF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20817607
26490400
23219531
19303849
|
PRKDC
|
LIG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
15194694
15941674
17570479
|
PRKDC
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
107.0
|
1.0
|
Omnipath
|
18454178
9488723
19321613
21930799
19305155
25487737
22819196
20493860
17570479
12607005
16673875
26976643
17723002
21151168
16039583
21514376
26438602
19049966
20368801
23916969
16935931
27919340
17923115
16061642
18438399
20157519
20461094
21690091
24253929
19531483
26960975
25168287
18758438
19268590
27813335
25690891
17210576
26748709
18406329
23972723
17412408
34429760
27551505
12692309
29221122
20703100
16861886
25070753
27332952
33691101
33863809
23653357
21283714
16788066
19781914
20205745
20860841
21389100
16148027
20116089
15610743
20192759
20224553
14627815
24893124
10734083
20488183
23185622
18157161
33945602
30573684
12766154
25699710
18755145
27738310
10477747
34504648
16820894
20356835
19014481
20713529
17525342
23671119
26114388
23355489
28790110
23678292
20118229
23166506
33986864
15604242
16377563
20609246
12907603
26119999
25072018
15289343
23891091
25269479
23620287
33731502
22972376
34282773
26578593
|
PCNA
|
RFC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8999859
12400013
15225546
19285992
10353443
12192049
9649448
26496610
12045192
12171929
24958773
8861969
9092549
|
RNF8
|
H2AFX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
15496928
15549137
15655342
17303408
17660363
18001825
18006705
18171670
18212739
18583988
18590585
18678709
18678890
18809224
19217833
19270065
19490890
19772495
20021983
20064462
7575488
9407949
|
RNF8
|
H2AZ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18001824
19797077
|
RNF8
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19772495
7575488
18590585
17303408
18001824
18678890
18583988
18001825
18678709
12607003
9407949
17660363
18006705
15279786
15459660
|
SSRP1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15171726
23810005
1406642
19946334
|
CSNK2A1
|
SSRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
19007248
15659405
20068231
17287340
22113938
|
ESR1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21411498
12122114
21693539
18519947
16690106
10805720
19360348
23409030
18754863
|
HIF1A
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18754863
15048086
17699105
16961934
|
USF1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19047367
12941894
12970752
16010690
12044867
|
CSNK2A1
|
TOP2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
19007248
16565220
17081983
18767875
19664995
15302935
10942766
19098900
20068231
18452278
7499337
9761967
18669648
8939955
18691976
17287340
19651622
20058876
19691289
9804834
19664994
11940573
7961967
16964243
|
UBE2I
|
TRIM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
17942393
17079232
25114211
18488044
17298944
18082607
|
VCP
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
33444648
11733065
28115426
15652483
10811609
29153394
|
PCNA
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
10858306
11283614
11585362
11756412
11948190
12202749
12637553
14624239
14726013
15385537
15703371
15871698
16216273
16442856
16449207
16697054
17055429
17116323
17426133
17599061
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19748837
19847258
20027199
20056333
20064462
20691907
20713526
20955519
21376743
21727086
2191300
21922195
22021614
22455312
22657828
22743550
22973052
23082994
23110144
23161013
23253856
23414611
23485469
24036544
24050180
24709898
9407949
|
WRN
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
WRN
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
10858306
11283614
11585362
11756412
11948190
12202749
12637553
14624239
14726013
15385537
15703371
15871698
16216273
16442856
16449207
16697054
17055429
17116323
17426133
17599061
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19748837
19847258
20027199
20056333
20064462
20691907
20713526
20955519
21376743
21727086
2191300
21922195
22021614
22455312
22657828
22743550
22973052
23082994
23110144
23161013
23253856
23414611
23485469
24036544
24050180
24709898
9407949
|
WRN
|
TERF2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11283614
12202749
12545156
15155580
15385537
16449207
17055429
17116323
17550342
17965729
18398454
18524993
18558713
18584027
18809224
19490890
20027199
20064462
20691907
20713526
20818389
21376743
21733352
2191300
21919891
22657828
22743550
23082994
23140366
23161013
23253856
23869868
24036544
24050180
24709898
9618481
|
WRN
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
36.0
|
1.0
|
ACSN
|
11283614
12202749
12545156
15155580
15385537
16449207
17055429
17116323
17550342
17965729
18398454
18524993
18558713
18584027
18809224
19490890
20027199
20064462
20691907
20713526
20818389
21376743
21733352
2191300
21919891
22657828
22743550
23082994
23140366
23161013
23253856
23869868
24036544
24050180
24709898
9618481
|
TERF2
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
15665826
18212065
12181313
|
XRCC5
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
CSNK2A1
|
YY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22184066
23226345
|
PCNA
|
H2AFX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
H2AFX
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
LIG4
|
XRCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
11163244
12032095
12471202
15385968
15703371
16439205
16697054
17088286
17638872
18077224
19346677
19473888
19546231
196269035
19772495
19808869
19847258
20691907
21175350
21211721
21270334
21300785
21376743
22055391
22469522
22713970
22743550
23178593
24050180
9242410
|
LIG4
|
XRCC4
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
11163244
12032095
12471202
15385968
15703371
16439205
16697054
17088286
17638872
18077224
19346677
19473888
19546231
196269035
19772495
19808869
19847258
20691907
21175350
21211721
21270334
21300785
21376743
22055391
22469522
22713970
22743550
23178593
24050180
9242410
|
LCK
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9500442
10571988
25386784
11145737
7539106
27748765
|
LCK
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
20028078
24332539
898671
16285729
15708849
17050525
15699036
17570479
11005864
10669745
10636924
|
GZMB
|
IGF2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11081635
|
ZEB1
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
22.0
|
1.0
|
ACSN
|
10048576
16556862
17012742
17486063
19208835
19839049
19935649
20589835
20702634
20706219
21051859
21081489
21159887
21224848
22286765
22439866
225147423
22514743
22945800
24335145
28212565
9811054
|
ZEB1
|
SOX2
|
â—¼ UP_REGULATES
|
✅
|
+
|
22.0
|
1.0
|
ACSN
|
10048576
16556862
17012742
17486063
19208835
19839049
19935649
20589835
20702634
20706219
21051859
21081489
21159887
21224848
22286765
22439866
225147423
22514743
22945800
24335145
28212565
9811054
|
ZEB1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
17997862
16424029
17615296
23890107
23160379
19435871
18411277
23667256
20139075
12508111
12714599
23518002
20207041
16862183
22249256
18321996
18805502
19706487
19839049
22147512
23743934
15674322
19921427
16804902
20332115
10949939
21771732
18487993
17655524
15311212
12161443
21593765
|
ZEB1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
15169839
9389648
17615296
22796940
19839049
20818389
21224848
20519943
21685935
12508111
11309385
11074002
225147423
19597490
12743038
14673164
|
VCAM1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22623428
19738201
11751331
|
FN1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9117345
9842903
19738201
11010812
|
TERF2
|
TERF2IP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
17145710
19651898
15316005
27214791
10888888
21217703
19287395
15383534
26496610
23086976
19164295
15100233
16880378
26450775
21829167
10850490
28082411
23307557
21044950
14565979
|
CEBPA
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22553076
20725087
15664998
15110775
18619497
19059241
9367890
15158467
23071089
10862621
15632071
16580992
|
PPARG
|
PDX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18718916
19237535
16489446
20332343
|
PPARG
|
SOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15590897
16951334
19535992
17337254
|
PPARG
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19466435
18278065
15908479
16321227
14693716
12055599
|
UBE2I
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19692572
15507114
26192107
|
SPI1
|
FLT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10734131
11672593
11964313
12032143
12803886
12811837
16283355
16418395
20510871
|
CEBPA
|
SPI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17671233
24429361
14636649
20972335
12949251
14592841
12032776
|
SPI1
|
CD40
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10823830
11481336
14962802
19801646
|
CEBPA
|
SPI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10397723
12091339
|
TFAP2A
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9328434
17224907
12391156
10523846
9632747
21377456
12903198
|
ESR1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12726856
14500345
17893710
19383788
19593637
20101232
|
CSNK2A1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
10837139
11348595
20976471
17928543
20558317
10671551
17374729
21285348
11972058
21506126
11689703
10747897
10671552
16707567
|
HIF1A
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20513003
18174278
16924414
19030186
|
HIF1A
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17615296
9157999
9278421
11708773
16716598
12080085
10403805
16887934
15181457
7539918
12490555
1823643
12829734
13130303
15451019
9746763
8943284
15111329
9159130
11566883
21041997
|
BMI1
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
BMI1
|
RNF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
16710298
22493164
22902369
20068231
22325352
25355358
17157253
16751658
26496610
16714294
26468281
26151332
12183370
12589020
21772249
25843776
20601937
32296183
21676867
27647897
15563468
27705803
16359901
24457600
19636380
|
AR
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14521927
21055159
20610535
|
TFAP2A
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19089912
11688971
11050170
10588870
|
USF1
|
CEBPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22719268
16537832
8076602
21680747
8493090
7862113
8585944
17239350
|
AR
|
UBE2I
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10383460
8798622
19692572
12764129
|
UBE2I
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10383460
8798622
19692572
12764129
|
CSNK2A1
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21930781
17289674
|
AR
|
UBC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17409431
20610535
17721441
|
UBC
|
PRKN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
24784582
26162776
26161729
25847540
24751536
26254304
23670163
26116755
27284007
25474007
26260794
22724072
25969509
24856362
|
AR
|
ETV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17634427
19789348
20610535
17505060
|
CSNK2A1
|
TERF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18347021
|
CSNK2A1
|
NKX2-5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9858576
|
CSNK2A1
|
MME
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22767595
20957047
|
CSNK2A1
|
HOXB7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11290787
|
CSNK2A1
|
HNRNPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19651622
20058876
17081983
20166139
15687492
18691976
20068231
18452278
19664995
17693683
17287340
19413330
12564933
18669648
15302935
|
CSNK2A1
|
TFAP2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21777522
|
CSNK2A1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11139588
26703694
9337862
20043841
11432835
11507039
9528769
7838153
|
CSNK2A1
|
TCF7L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11711551
18452278
|
CSNK2A1
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11877451
32863206
|
ESR1
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8300756
8912864
8732679
11038749
15831516
15870697
10076999
9626663
18414489
|
ESR1
|
HSPB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15833836
10960840
11174852
8923463
|
ESR1
|
PGR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
12829318
12554765
12446585
11000528
15019994
8043503
23027806
9058379
9717846
18414489
12706304
10835496
16293641
18784357
12761896
8145766
22543272
15743834
8530508
10894148
|
ESR1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8299561
11000528
22391641
|
AR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12389206
11032808
16713569
11000528
18988627
|
DDX17
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19995069
21182205
12738788
20348541
19718048
20663877
25604459
|
PGR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
22396492
16168121
12612073
11000528
18988627
26153859
|
ESR1
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
17641689
15831516
9717844
9841885
|
AR
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12020745
20610535
14684616
18451309
|
AR
|
THRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
AR
|
KLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
17433535
8626436
11059779
15640443
7686046
11006269
12111703
15368351
24307657
9316650
9719026
11867260
12376473
14767470
16275987
11994312
17075604
20181722
9211894
16342680
12917209
18092350
12648523
17011549
11238180
20069563
10547578
16140973
22245379
12539223
20568894
20103546
18758709
21981678
21541973
12463425
12958311
11894840
19389135
17534890
23662037
15923603
16434977
14517289
22695118
10075669
11377978
16137620
11299734
15131260
21780100
16508948
16425097
22473899
14715080
10625666
18640093
21885566
12670590
14729601
16452400
16081584
10898343
11571582
9044850
15833875
16914734
23884959
15640095
15543614
7514587
12376534
12114445
15557561
18780293
23667504
18829551
12782640
16724108
17426252
11504717
19274665
11034093
17566103
12651911
22179832
21308712
16373397
19013180
22155408
9052414
11532861
17094454
17653089
20709811
22654108
22597536
15514031
|
HSPB1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19767773
17974989
|
AR
|
KLK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1712248
19345326
25241761
|
NCBP2
|
METTL14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
POLR2A
|
POLR2E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RNF2
|
H2AZ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17636032
15386022
|
POU2F1
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12144930
9694713
17192276
|
NKX2-5
|
GATA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19479054
15653675
16137232
|