Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NCK1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
RAC3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17625931
LPAR3 GNA12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22863277 15856019
LPAR3 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12531543 31160049
LPAR3 GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22863277 15856019
TRIO BLMH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FLNA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
WASL FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
FYN DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
FYN NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
WASL NTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
NTN1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
NTN1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
TRIO RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
DCC RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
NCK1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
NCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
RAC1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
DAB2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
WASL NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
NCK1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
NCK1 DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
WASL SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
SRC DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21849478 26323693
TRIO CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
DCC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
CDC42 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
WASL PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
GNA11 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA15 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA14 GNA11 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
GNA11 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
WASL DCC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
WASL TRIO â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
GNA14 GNA15 â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
MYC CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CDC5L EXOC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
CDC5L TRIO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 17043677
MYC EXOC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC FLNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
RAC1 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PTPRF RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 25458010
NAV1 DISC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 33961781
ZN232 TRIO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN785 TRIO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NCK1 WASL â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CDC5L DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
TRIO EXOC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
EXOC1 DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
TRIO DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
TRIO RHOG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25065758 32203420 31871319
GNA11 GNB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ARHGAP5 RHOA â—¼   GTPASE_REACTION ✅ - 0.83 0.83 Signor 32203420
RAC1 TRIO â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BRCA1 FLNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22990118 20305393 16713569 26831064
FYN PTPRF â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12496362 31413325
TRIO PTPRF â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8643598 27880917
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
DAB2 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12473651 16189514 16713569
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
MYC BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12646176 11916966 16713569 20215511 9788437 30415952 14612409
MYC RHOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
NTN1 FYN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
FYN DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
NTN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
RAC1 TRIO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21422296 25065758 31871319 32203420 11595749
TRIO RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31871319 26344197 10948190
TRIO RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9464532 10948190
SRC DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
SRC ARHGAP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7542246 24858043 10592173
PAK1 RAC3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
NCK1 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RAC3 TRIO â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5220560 7744004
PAK1 NCK1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11278241 10805734 8824201 11157752 10026169 10330411 10372803 33961781 9851874 11557983 15784622
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9535855 11157984 21029865 16678097 19596003 23455922 9705280 31871319 25150978 12879077 12606577 10360579 31478661 10684602 8107774 21048135 23175184 18057010 10802735 21167153 15548653 12650940 18426980 7744004 20936779 24276241
WASL CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9422512 15834156 16293614 11331876 10724160 20936779 10781580 31871319 21311754 11943145
CDC42 WASL â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
PAK1 RAC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 24625804 19327867 15143066 9535855 17245428 11134022 15673687 15289329 16492808 16551621 21029865 16678097 19596003 26175416 17389360 31871319 24056087 25843002 25150978 12879077 15212766 19693014 11030651 16630611 20810653 8107774 11130076 25468898 29615491 19732720 19270716 21474670 10706722 19277120 10802735 21167153 24172987 21454543 15548653 16002993 12650940 18426980 19961560 11950930 24792722 15688026 7744004 20936779 25819133 15075243 22581261
DCC NTN1 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
WASL NCK1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11340081 17474147 26496610 16595635 33961781 26871637
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GNB1 GNGT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
NCK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10805734 11278241 10026169 23109003 11096073 10330411 8798379 11278553 16490784 11157752 15784622 9024622 9755165 8824201
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18598695 18088087 24278701 12198493 26009991 15024089 25472536 23246867
GNGT1 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25675501 8636150 9789084 10360181 12782285 19168127
TRIO FYN â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NCK1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11369622 12558988 15494733 20151426 12590707 16293639 7505391 15728464 11278857 16713569 10753828 15494732 10085136 15494734
FYN DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15557120 21849478
FYN PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12496362 18854310
TRIO NTN1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NTN1 DCC â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
NTN1 DCC â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
NTN1 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19721007 8861902 26190107 9950216 11239160 25881791 10399920 12810718
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
TRIO RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9464532 8643598 10798395 32203420 10847683 11595749 21422296
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
ARHGAP5 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 32203420 9407060 10592173 8537347 12842009
RHOA PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10208419 12087088 16153436 15657578
TRIO NCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NCK1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11340081 26496610 17474147
TRIO SRC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
CDC42 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17145710 10559936 11331876 10940259 9422512 11943145 10511705 15020669 8625410 11340065 10219243 15003621 15834156 16293614 20936779 10934474 11413130 15713627 11950587 10724160 10467124 10781580 11248548 18719708 10613909 10461188
TRIO PTK2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
DCC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15494733 29479476 20434207 15494734
PTK2 TRIO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12551902
TRIO DCC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262