Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 ACAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 FLNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FOXO1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15059979 10871843
ARFGAP3 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
TLR2 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17126326 5219377
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
PML EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12673202 9819401
SH3KBP1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
NCL FOXO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FOXO1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20082134 18444242
CREBBP FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10973497
FOXO1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18444242
HGS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
HGS ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
HLA-E PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
WASF1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307379 21946561
SH3KBP1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220762 8246987
PIK3R1 FLNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 PIK3C2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TLR2 PIK3R1 â—¼   PROXIMITY 2.0 0.8 intact 23247210 8402360
PXN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23397142 25241761
PIK3R1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23397142 25241761
RPS3 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VPS33A DCTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
NCK2 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12810700 12215529
NCK2 EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
NCK2 EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
NCK2 GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 12695502
CAV1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
WASL ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
EFNB2 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTB ITSN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTB EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTB EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTB NEB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
ACTB MYO1G â—¼   COLOCALIZATION 2.0 0.8 intact 19968988 7307224
ARPC2 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
CTTN ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
ACTB CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
ACTB ARPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
EFNB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
CFL1 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SH3GL2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WASL ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTG1 ITSN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTG1 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ACTG1 EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ACTG1 EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
WASL ARPC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32296183 25416956
WAS LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7208262 16107303
ABI1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
SRC PXN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574420 14665621
WAS PSTPIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216858 14707117
WAS PSTPIP1 â—¼   COLOCALIZATION 2.0 0.8 intact 5216858 14707117
HSP90AB1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYLK2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CAV1 TRAF2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213300 11112773
TRAF2 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 10490605
HRAS VPS37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
HRAS EFNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
HRAS EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
HRAS EFNB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2201922 7478585
CREBBP IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
HSP90AB1 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NOSTRIN RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22751148 8403585
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
TLR2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11101877
DVL2 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11779461 18162551
RHOA NCL â—¼   COLOCALIZATION 2.0 0.8 intact 21281639 8086571
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
RHOA PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 14681219
SORBS3 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DVL2 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23151663 19379695
WASL SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
SDCBP SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18832467 0808171105
ACAP1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DIAPH2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12577064 10678165
SRC GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 12695502
SRC SDCBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18832467 0808171105
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16432186 0510562103
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
SRC ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
AFDN SRC â—¼   COLOCALIZATION 2.0 0.8 intact 5219918 17491594
TRIP10 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212318 10713100
NOSTRIN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22751148 8403585
CDC42 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
CDC42 DIAPH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15190208
PRPF40A DIAPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DIAPH1 BAIAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 10814512
CAV1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20956295 1005574107
PTPN2 ITGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15592458 8284715
ITGA1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19397781 26148229
PTPN2 ITGA1 â—¼   COLOCALIZATION 2.0 0.8 intact 15592458 8284715
ITGA1 PTPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592458
PRKCZ PARD6A â—¼   COLOCALIZATION 2.0 0.8 intact 17057644 5219258
SNX9 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217519 15703209
ITSN1 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
DNM2 SNX9 â—¼   COLOCALIZATION 2.0 0.8 intact 5217519 15703209
ITCH SH3GL2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5216835 14684745
SH3GL2 ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 5216835 14684745
PRKCZ NCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9388266 16189514
PRKCZ MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667433 17646398
PRKCZ MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667433 17646398
HLA-B CD8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9331948 10809759
HSP90AB1 NLRP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29712950 17435760
WASL PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
ITGA2B PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11476890 16919435
PTK2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893324 22952866
EFNB1 GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 12695502
EFNB2 GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 12695502
EFNB3 GIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 12695502
SKA1 TUBA4A â—¼   COLOCALIZATION 2.0 0.8 intact 5219311 17093495
MAPK10 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19782076 7263131
ABI1 NEB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15048123 5216987
ITSN1 WASL â—¼   COLOCALIZATION 2.0 0.8 intact 5214632 11584276
WASL CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 6541884 18344974
FNBP1L ACP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ARPC1B WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215256 11943145
VPS37A VPS25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
VCL PRPF40A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
APC2 CTNNB1 â—¼   RELOCALIZATION ✅ - 0.8 0.8 Signor 10980707
TRIP10 WAS â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
PIK3R1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16273093 5218056
FNBP1L WASF1 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
WASF1 RAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 9843499 19363480
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
RSPO3 LGR4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 24050775 25504990 29752411
SNX9 DNM2 â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 5217519 15703209
ARPC5 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
ITCH RPS27A â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ACTB DYNC1H1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ARPC4 WAS â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ABI1 BAIAP2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CREBBP FOXO1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
DCTN5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
PIK3R1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EGFR DCTN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
ARRB1 HGS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
PAK4 ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19778628 29100370
ACTB FHOD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12665555 34079125
PAK4 RAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 11756552
ARRB1 ITCH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17947233 18544533
WASL ATG4C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
PIP5K1A PIP5K1C â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
NCK2 WASF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
DNM2 SH3GL2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
NCK2 WIPF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ACTB CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17502619 28734243
CXCR2 ARRB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 11170396
RHOJ CDC42 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 10967094
EFNB2 EFNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ACTR3B WASL â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
WASL RHOJ â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 31871319
UBASH3B WASL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EGFR CD44 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11606076 16565089 12093135 15597342 23265944
NCK2 ABI1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 16713569 33961781 26186194 11557983
ARPC2 WAS â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ARPC4 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
ARRB1 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33844281 19202075 16432186 23242524
CDC42 CAPZB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ACTB DCTN5 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CSNK2A1 PML â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ABI1 WASL â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
EGFR SHC4 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CD8A LCK â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
SHC2 EGFR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8610109 16273093 24430869 22973453
TRAF5 TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9718306 32296183 21903422
EFNB1 SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 8878483
RPS27A ZRANB1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
EP300 FOXO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15890677 24419059 25609649 18786403 11896584
CDC42 DNMBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31871319 31478661 32203420
ITCH BIN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26613292 28235806
ACTB DCTN2 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PACSIN1 PACSIN3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ITSN1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 15824104
ITSN1 CDC42 â—¼   GTPASE_REACTION ✅ + 0.86 0.86 Signor 30540523
FCHSD2 ITSN1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
WASF1 ABL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10970852 18559503
EGFR SNX9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR WASL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
NCK2 WASF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
NCK2 WASL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781 26186194 26871637
PRKCZ PARD6A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5219258 17057644
PARD6A PRKCZ â—¼   COLOCALIZATION ✅ 0.87 0.87 mint 5219258 17057644
DCTN2 CAPZB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 26344197
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR SH3KBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ARPC4 WASL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CAV1 RAC1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EGFR UBASH3B â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PIK3R1 PTK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
WASL WIPF3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BAIAP2 RAC1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ACTB CFL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ABL1 ABI1 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 21320496
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PACSIN2 PACSIN3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ACTB CAPZB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
LCK CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 8576267
PTK6 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8940083 22973453 16273093
TRAF2 CAV1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11805080 16189514 16713569 11112773 32041822
WASF1 ABI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31980649 26496610 27173435 15048123 26344197
TLR2 CD14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18765807 10395652 16189514
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
DVL2 ARRB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 16189514 11742073
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PACSIN1 PACSIN2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GIT1 PXN â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ABL1 PIK3R1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ACTR3B ARPC5L â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
SH3GL2 SH3KBP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CD44 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
TLR2 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17126326 24658140 25402006 31980649
EGFR SHC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 28724758 22973453 24658140 24430869 25402006
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
EGFR ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RAC1 IQGAP1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 18809683
NCK2 GIT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
NCK2 EFNB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 12606549 15764601 12206665
SSH1 ACTB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 11832213
FHOD1 RAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15051728 15642356 11590143
DVL2 WWP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34139860 26701932 31340145
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
DCTN2 DCTN5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 27173435 26186194 26344197
DNMBP WASL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24332715 14506234
WASL WIPF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 23414517
TLR6 TLR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23155421 12077222 20067962
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PACSIN3 WASL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
ARPC3 WASL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
ACTG1 CFL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
EGFR PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HGS RPS27A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
TRIP10 WASF1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
DNM2 SNX9 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
DNM2 ITSN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ARPC3 WAS â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
ABL1 ABI1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5219329 17101133
SRC ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11494128 17474147 12522270 11781820 17318191
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
ACTB BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
NCK2 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 16713569 22973453 24658140 10026169 1333047 9737977 25402006 9843575
EGFR TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 23972990 25402006 18271526
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
NRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
RAC2 PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7744773 8645157 11803464
EFNB1 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11557983 16713569 16636066
PXN CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15719014 25241761
TRAF2 TRADD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 9020361 32296183 16713569 11479302 11181075 19815541 10892748 12796506 27768232 23955153 8702708 32968279 8565075 30561431 23429285 10911999
BAIAP2 WASF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11130076 16713569
RAC1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18426980 18423204
RHOA PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22820501 22479341 27228149
ACP1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19088431
AFDN SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17491594
SRC EFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8878483 16189514 22279592
ITSN1 CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15824104 12006984 11584276
PAK4 CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 16189514 29734338 17353931 11756552 31478661 20936779 9822598 26598620 31871319 26344197
ACP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16287083 12438242
WASL WIPF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16055720 33961781 23414517 22939629
ITSN1 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PTK2 PXN â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 15688067
CDC42 PAK4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PXN VCL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ACTR3B ARPC5 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
FNBP1L WASL â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
TRIP10 WASL â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
IQGAP1 RAC1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CDC42 IQGAP1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
RAC1 CAV1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 24625804 27250250 22614015 20460433 31871319 15976327
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
DIAPH1 DIAPH3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RPS27A SH3KBP1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
NCK2 EFNB1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 16189514 16713569 11557983
PXN PTK2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 25795725
ACTB PFN1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ABI1 WASF1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RHOA TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6A PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
APC2 CTNNB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ABI1 ABL1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
PTK2 PXN â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
IQGAP1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5221163 8798539
CDC42 IQGAP1 â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 18809683
WIPF2 NCK2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 12213210 33961781 26186194
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
WAS CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8625410 5221000
WASL WIPF2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ACTR3B ARPC2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ARPC2 WASL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
RRAGC RRAGB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 25567906 21981924 33961781 28716898 11073942 20381137 25561175 24337580 22980980 22424946
ACTR3B ARPC1A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
C5 C9 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ACTR3B ARPC3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DCTN2 DYNC1H1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ACTR3B ARPC4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDC42 PARD6A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
ABL1 ABI1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17101133 9593709 12672821 9010225 18328268 8943360 20598684 11418237
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
ARPC4 ARPC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 23148219 11162547 22863883 33961781 24981860 22939629 26344197
ARPC3 ARPC5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23148219 26655834 22863883 33961781 24981860 26186194 22939629 26344197
WASL CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9422512 15834156 16293614 11331876 10724160 20936779 10781580 31871319 21311754 11943145
WASL ITSN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 18539136 11584276
ARPC1A ARPC5L â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDC42 ITSN1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDC42 WASL â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
C5 C7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CAPZB DCTN2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ACTR3B ARPC1B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RPS27A RPS3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
BAIAP2 CDC42 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARPC2 ARPC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 26655834 22863883 24981860 22939629 26344197
ARPC2 ARPC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 11162547 22863883 33961781 24981860 22939629 26344197
TRADD TRAF2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DCTN2 DCTN5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ARPC2 ARPC3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 11805826 23148219 22863883 33961781 24981860 9230079 26186194 22939629 26344197
ARPC4 ARPC5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12451597 11162547 26655834 22863883 33961781 24981860 22939629 26344197
ARPC1B ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1A ARPC5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1A ARPC3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC4 ARPC5L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC42 WAS â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RRAGB RRAGC â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
HLA-E ABL1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10358164 11015446 11062502 12731048 15120186 15536084 22464172 2731048 8478617 9485206 9486650 9655483
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
LCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16076903 16787943 17570479 11847100
ABL1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7615549 15817476 11774284 16254239 15107421 12408869 15572663 11695992 15592455 16094384 10823820 20841568 16713569 9603926 7537852
ABL1 SORBS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16831423 20841568
ABL1 DNM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17474147 20841568 19833721
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20861316 17306540 20841568
ABL1 PSTPIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11163214 20841568
ABL1 TRIP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19631450 20841568
ABL1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 17145710 20598684 18328268 12591740 9593709 20841568 18083107 7590237 11418237 12672821 17389395 19534553 8943360 17101133 9010225 11163214 26428302 21320496
ABL1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17389395 19901323 16199863 19664994 20068231 18707149 18452278 20146487 20841568 19415658
ABL1 APBB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20110615 15031292 18922798 26255939 11279131 22506131 20841568
CD44 SLC9A1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16104017 9712871 15090545 8901634 11350981 17050540 15035633
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
CAPZB DYNC1H1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PTPN2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15592458 15588985 9488479 10488121 11514572 11479308
SNX9 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16316319 24658140 25402006
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR PIK3C2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 31980649 10805725 11533253 24658140 25402006
EGFR NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1333047 23331499 10026169 9737977 24658140 16713569 25402006 9843575 1333046
EGFR SHC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11350724 16273093 8760305
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16713569 16919435 25402006 10806474 29435030 20473329 7657702 19339212 17496910 15657067 24658140 19625610 7529872 20802513 31980649 10545505 24043698 15951569
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
EGFR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17496910 26918608 7797556 25241761 19531499 16273093 8662998 14967450 16713569 21701776
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
CTNNB1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17254970 15905404
HGS SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
IQGAP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 31980649 28007913 8798539 19079338 9199170 8670801 8702968 15695813 15217908 8756646 18809683
IQGAP1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 17145710 9182573 8798539 12377780 9199170 8670801 17563371 8702968 12745076 15695813 21876773 8756646 12900413 18809683
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
IQGAP1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7731720 14970219 18567582 16135787 17563371
MYL12B MYH10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
MYH10 MYH11 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PRKCZ MYH10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16611744 25869664 30655296
NRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9069260 25241761 10212255 11313862 9150145 16713569 15021914
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CTNNB1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10477752 25241761 16219695 11716761
PTK2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10806474 8649427 7537275 10973983 12554777 16713569 9416004 19889638
LCK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8294442 11337495 8246987 14583609 11526404 15032589 23109003 9461588 7504174 8397196 10488096
PIK3R1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7629060 8034624 12086876 12515821
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CSNK2A1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17145710 16873060 19380586
NCK2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10592173 11950595 16713569
CD14 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
DIAPH1 ACTB â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
PFN1 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17541406 8413665 563468 10600384 10411937 10592173 19000816 16189514 19338310 9463375
ACTB CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 8913641 25416956 15364581 10592173 19704022 16189514 31515488 32296183 16713569 29892012 10980704
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
CDC42 ACTG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
DIAPH1 ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTG1 BAIAP2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
WAS ARPC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 23148219 12769847 9889097
CD8A LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16818755 14500983 8814252
LCK ACP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16890200 9038134 10671492 10980198 15951569 17016520
LCK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11369622 12590707 15728464 9257837 10753828
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC1B ARPC4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC4 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC4 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
TRIP10 PXN â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10467124 10511705 10713100 11395419 11520460 12177428 14707117 15001467 15541654 16293614 16606694 17785506 19741094 21178402 23212475 8625410
DIAPH1 PXN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15866170 16292343 17306570 17575049
GIT1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11448998 14523024 10896954 12153727 16628223 12629171 10592173 16713569
PTK6 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17081983 15572663 15592455 18676874 18083107 7537852 17389395 7493940 7615549 19534553 11774284 15107421 12408869 10823820 16254239 15817476 16094384 19304789 16212419 21423176 15951569
PTK2 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 16298995 26053221 15688067 15572663 15592455 7963537 17389395 25405379 26546726 9658172 15107421 22581436 10823820 16254239 25226367 15817476 10330411 9756887 19543320 9054445 10545505 18707149 29127427 15494312 10764815 7537852 9442086 33823745 12408869 20419088 20655620 22270917 18669648 28373581 10455189 16094384 23936270 19138410 22638989 11337490 11514617 27402964 16713569 7615549 10931187 11774284 26700725 27708220 20068231 20473365 28928239 7561682 34475475 28427224 28068967 8922390 24885567 23209645 27669437 15212693 26711338 9422762 11304546 28214467 26697169 12065577 28415719 10753828 11919182 24364863 9230116 11113628 21741599 10417825 15252114 24642576 22044652 21034468
SRC PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9636140 28214467 15572663 15592455 16713569 14665621 25795725 7537852 7615549 25405379 11774284 26700725 25182764 15107421 7534286 2472406 12408869 11695992 17570479 10823820 7525621 20103658 16254239 15817476 23109003 27447856 28626446 16094384 18363833 19543320 24364863 28376152 19138410 25323586 27941878 23457577 10085298 22638989 27669437 15212693
TRAF2 TRADD â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRAF2 TRADD â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRADD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 8702708 8565075 14585074 16713569 27383048 18621737 14743216 12796506 21741934 11181075 21119000 10911999 20203691 10892748 23955153 11112773 18439848 32296183 15485837 12887920 12517920 19815541 11479302 9020361
TRAF2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
HRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS AFDN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10334923 10922060 8557659 10545207
CDC42 WASF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10360578 8643625 12181570 11052943 15834156
SRC WASF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16317717 23354023
TLR2 CD14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16455995 17889651 10426996 15241424 16880211
CD14 TLR6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10549626 22028855 10426996 10364168 16880211 10490993 14977973 11123271 11431423 18178856
CD14 NLRP3 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
ITGA5 CFL1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 15866889 16919435 17522712 18037882 19161977 19339212 19454690 19487819 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGA5 PTK2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGA5 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10545505 7657702 9003039 11927607 19339212 19487819 19161977 16919435 7529872
RAC1 RSPO3 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 RSPO3 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 27331412 7641885 8655584
RAC1 BAIAP2 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11274345 11544274 11756498 12054568 16702231 18000759 19151919 24459205 27331412 9655398 9843499
DVL2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15262978 12533515
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
RAC1 PIP5K1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16212495 12480336 11152757 10679324 14681219
RAC1 FHOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15642356 15051728 11590143
RAC1 PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16212495 12874273 12480336 11152757 10679324 14681219
RAC1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
RAC1 BAIAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11696321 9843499 16702231 16212495 11130076 12480336 12054568 11152757 16713569 17003044 19171758
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
RAC1 PIP5K1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16212495 12480336 11152757 10679324 14681219
RSPO3 RHOA â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
RSPO3 RHOA â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605
PARD6A RHOA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14657501 14722617 14744429 15265520 15761148 16472676 21572392 22949611
RHOA PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10208419 12087088 16153436 15657578
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
RSPO3 LGR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25504990 24050775 21909076 29769720 21693646 29405118
DVL2 PFN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18798527 19523939 17373907 17021034
DVL2 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
ARRB1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11742073 16713569
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
SRC ITGA9 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11476890 16099633 16919435 17496910 17517963 19734908 22203675 22370635 25572304 26552706 27216177
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
PRKCZ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 10527887 11447289 19615955 16488589 6321473 8321321 12845332 11313945 16189514 12040186 19568798 15567848 14585353
PTPN2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15696169 18948751 27611995 22080863
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
SRC ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17456469 17456551 16432186
SRC VCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28592633 25115937 15229287 28684609
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
SRC CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19802004
SRC PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14691141 20850356 15738269 15623515 16616931
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 27603901 22823952 7680654 9748248 28522963 19419567 19690332 16497976 15592455 19413330 25077552 17389395 19534553 20068231 28769876 17570479 20708589 19273217 18491316 18669648 16162656 25682866 12522270 18088087 22761768 26142315 17287340 27009365 10921917 9683637 24465712 27758765 24675741 12601080 18707149 16212419 15169891 7519605 17016520 11389697
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
SRC GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14523024 24699139 22302306 20689073 17570479
WIPF3 CDC42 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
CDC42 WIPF2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
ITSN1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 30540523 23331499 11584276 15824104 12006984
CDC42 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 10360579 10559936 10940259 8643625 9422512 9742969 25502805 10684602 15075243 10511705 15020669 12235133 12769846 8625410 11340065 15361624 16189514 15003621 16293614 20936779 22252508 10934474 11413130 15713627 10747096 11950587 27871158 10724160 10360578 10713100 10467124 10068673 9660763 25758716 11248548 10802735 31515488 18719708 10613909 10461188
CDC42 BAIAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17430976 20936779 11696321 24076653 11130076 12504591 16713569 24584464 19171758 11157984
CDC42 PAK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10559936 11756552 29734338 15020669 16189514 11340065 15003621 20936779 10934474 11413130 17353931 22653441 11950587 26598620 11248548 9822598 18719708 10613909 10461188
CDC42 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17145710 10559936 11331876 10940259 9422512 11943145 10511705 15020669 8625410 11340065 10219243 15003621 15834156 16293614 20936779 10934474 11413130 15713627 11950587 10724160 10467124 10781580 11248548 18719708 10613909 10461188
CDC42 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10934474 14676191 10873802 11260256 16189514 12606577
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
PAK4 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28007610 22173096 26068882 25560280 23543898 30755582 29330094 29399291 25335797
SNX9 DNM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27107012 15703209 15299020 18388313
ITCH SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14684745 17038327 26613292
NRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PTPN2 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16293614 17145710
GIT1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10938112 12473661 12629171 24608434 16713569
NRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
CSNK2A1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11062067
CSNK2A1 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 10068673 12769847 18088087 9742969 12235133 15592455 12769846
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15822905 17081983 16565220 18088087 29854279 2492519 34359868 25995454 1956339 16094384 15581363 18591256 16964243 92065884 15302935
APC2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 23840886 10021369 8638126 16510875 10980707 10074433 9823329
MAPK9 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 19623618 18423204 25639486 22074626 19667122 18604449
ARRB1 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19782076 11356842 19879840
CTTN WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21079800 18344974 11830518
WASL ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894313 10781580 11943145
SSH1 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12684437 21525957 14531860 10592173 16713569 11832213 16230460
WAS RHOJ â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12456725 10967094 32302585 22971344 31871319 26299518
WAS ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11943145 10861055
ARPC1B ARPC5 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RHOQ ITSN1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 7721814 21454492 17214551 23255595 25678704 19258391 19713215 9857026 24297911
WIPF2 RHOJ â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12456725 10967094 32302585 22971344 31871319 26299518
MYL12B MYH11 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
C9 C7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9038722 16999828 7691959 17505110 16079145