Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CAPN2 BAX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 21887410 23242420
TCF7L2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17404573 23671559
FUS BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
CAPN2 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12000759
CAPN1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12000759
PRKACA CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11909964 29478550
CDK1 NUMA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7769006 23921553
CLTC TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CLTC IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CLTC TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RRAS GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
KIF13A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TNFAIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 ARPC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TPM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ITPR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CTTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TUBB4A IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A6 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS3 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKN IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20301198
GRIN2A LRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
MAP2K6 MAP3K5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866172 8974401
LRRK2 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
RAE1 NUMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17172455 0609582104
OTUB1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN PPM1D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20093361
PSMB5 PSMB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6175987 17948026
PSMD2 PSMC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PRKACA PSMD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD2 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTR2B RAE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
RPS3 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS3 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HRAS SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEFL SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR TAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22153078 25083866
TUBB TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A6 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ATP2A1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB4A TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IRS4 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LRRK2 DYRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ATF4 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18471544
NEFL DYNLT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 NEFL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9039646 7745611
HSPA1L TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FCGR2B FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RRAS FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
FYN PSENEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN RRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17474147
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
HNRNPA2B1 AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AXIN1 CSNK1A1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11884395 23331499
MAX THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20876797 10871348
JUN MAPK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN MAPK10 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
TCF7L2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
JUN CTSL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9038212
JUN PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20638938 21113145
JUN PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16729332 20143420
MAPK9 JUN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
JUN MAPK10 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
PRKN JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20418918
PINK1 PARK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 21179058 23725295
PINK1 PARK2 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 21179058 23725295
PINK1 MAP1LC3B â—¼   COLOCALIZATION 2.0 0.8 intact 20153330 7557104
PIK3R2 HLA-E â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
TPM2 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TUBB CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR PPEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A6 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB4A TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP2K3 MAP3K5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866172 8974401
LRRK2 POU5F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
TUBB TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB4A TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CDC42 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704645 14724572
CAV1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20956295 1005574107
ESR2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138116 16423895
SP1 ILK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19176380 24361375
SP1 NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8961265
SP1 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20644166
ELK1 NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31146003 19687146
PRKACA PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8657310 9660757
PRKACA MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20713600
HTR2B GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11916537 31160049
GNAQ PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
GNAQ PLCB2 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
HDAC6 CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 8295686 21847094
PLCB2 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
IRS4 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16933034
PIK3R2 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8596638 11733063
HSPA1A MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNRNPA2B1 ATP2A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPA2B1 CLDN17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PSENEN NCSTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18201567 6174903
PRKN MFN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1231031 23620051
MFN2 PRKN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1231031 23620051
PRKN MFN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25915564 29921586
MFN2 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25915564 29921586
NR4A1 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16252282 14559918
MAPK7 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18429814
TFRC ADCY5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HTR2B KIF19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
COX6B1 NDUFS4 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
OTUB1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32814053 18954305
LRRK2 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
ESR2 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 25604459
LRRK2 ARPC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 20876399
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
LRRK2 TPR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
ARRB2 TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25241761 17620599
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
CYC1 NDUFB4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
TAF4 SP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11988536 9742090
PSMA4 PSMA2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 6175987 17948026
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
FYN GRIN2A â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
IRS4 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21706016 9553137
MBL2 CALR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18177377 8062452
RAF1 RRAS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10848612 19805522
CDC42 NCF2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
BCL2 RAF1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
MAPK9 JUN â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9405416
SOCS1 GRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
ILK RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23455922 26496610 25852190
PARK2 SNCAIP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NRAS RAF1 â—¼   RELOCALIZATION ✅ + 0.87 0.87 Signor 21779497
KATNA1 KATNBL1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HDAC2 SNW1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10644367 20467437 30737378
SOCS1 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
EPHA4 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31413325 16189514 16713569 12084815
HDAC2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17312152 18059533 16713569 15713621 17894944 12091390 16036112 12151407 21159880 12176973 20697349
RAF1 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16189514 7517401
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
SP1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25879517 10506225 16713569 33572115 16478997 17215518
PLCB1 GNAQ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16754659 12193606 11753430
OCLN TJP1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CAPN1 BAX â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19931333 21887410 23242420
AKT3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14766748 15642728 17525161
CTBP1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12676992 7834749 15613549
RAF1 BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8929532 8910675 12488548 9194558 15849194
ESR2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19211725 18223478 20664923
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
CAPN1 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11553682 11677266 10846184
ESR2 CAPN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IRS4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9553137 15316024
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
SP1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22412893 23995788
SP1 TNFRSF1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22019592 8954938 22615874
ATF4 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 1827203 20936779 23661758
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
RAF1 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11427728
CREB5 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26496610 8440710 33961781 25609649 26186194 24981860
CREB5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8378084 8440710
PPARGC1A NRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 16314495 18046414 18048642
PPARGC1A NRF1 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 16314495 18046414 18048642
PPARGC1A NRF1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 16314495 18046414 18048642
NCF2 CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7738010 9642115 16189514 11090627
TRADD MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9774977 15310755 18292600
PRKACA LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21390248 24351927
ITGA2 ILK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11112697 25100717 9456329
SP1 HSPA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1508207 1717345 2674689
SP1 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12538496 11479230
VTN C8B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2465906 7542572 2466593
MAP1LC3B CLTA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR4A1 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AKT3 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284
CREB5 JUN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ATP6V1C2 ATP6V1D â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
KATNAL1 KATNBL1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CALM3 CAMK2A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
NRAS RAF1 â—¼   PROXIMITY ✅ 0.93 0.93 mint 30194290
COX5B CYC1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ATP6V1B1 ATP6V1C2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
AKT3 MAP3K5 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
NDUFA11 NDUFS4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HRAS PIK3CG â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
NDUFA11 NDUFB6 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
DYNLT1 DYNLT3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
NRAS RAF1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
COX5B COX6B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
NDUFA11 NDUFB4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
NDUFA11 NDUFS5 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CYC1 NDUFS5 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CYC1 NDUFB6 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
JUN MAPK10 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
MFN2 PARK2 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
KATNA1 KATNB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CYC1 NDUFA2 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
ATP6V1B1 ATP6V1D â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ARPC2 ARPC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 11162547 22863883 33961781 24981860 22939629 26344197
HRAS RAF1 â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
RAF1 HRAS â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
NEFL NEFM â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
JUN MAPK9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NDUFA2 NDUFB6 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NDUFA2 NDUFB4 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NCSTN PSENEN â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BAX BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21778226 18981409 15899854 32064756 10620799 21199865 17289999 9194558 8358790 21671007 16642033 21458670 22262057 9388232 10716992 20865015 14980220 9111042 24141421 17097560 15231068 9463381 33961781 17525735 29749471 23479509 26004684
PSMB5 PSMD12 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMB5 PSMD2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
CYC1 NDUFS4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMA4 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA2 PSMB5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB5 PSMC1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB3 PSMB5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PARK2 PINK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMB3 PSMC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC1 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA4 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA4 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMB3 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMB5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA4 PSMC1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA2 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMB3 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD12 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA1 PSMA4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA1 PSMA2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMA2 PSMC1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA1 PSMC1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMC1 PSMD2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFA11 NDUFA2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NDUFA2 NDUFS4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMA4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA4 PSMB3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMB3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA1 PSMB3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BCL2 BAX â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
SP1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278953 10510469 11748232
CAPN1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20709625 21670566 21414921 16129881 17593948 14612448 21266584
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
BCL2 NR4A1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11704864 14980220 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 NR4A1 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 11704864 14980220 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
BCL2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
SP1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14660675 20435036 12032828 10542244 15713621
NR4A1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18835031 14980220 16434970 16713569
CDK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24097825 24677263 23638364 19917720 27231850 11774038 11326318 10766756
AKT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
PRKACA CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11909964
CDK1 PIK3C2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12719431
CDK1 NUMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 26832443 24241204 23921553 24109598
CDK1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21871177 19081932 19059439 19458393
CDK1 KIF20B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470801
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDK1 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20513426 26432751 28409123 27680387 28858266 26108642
CSNK1E AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 10535959 22682247 11884395 26496610 11487578 12000790
GRB2 FLT4 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 FLT4 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
NRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 FLT4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 34.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 12040186 12175651 12419216 12640133 12738796 12782630 14585353 15567848 15574420 15863030 16102570 16227978 16488589 16582911 16887996 17496910 17673906 18855897 19449109 19568798 19615955 21102635 21614932 24027568 26552706 7510700 8551221
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FLT4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9927207 8662748 7675451 7970715
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
JUN ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11356008 12832416 9218873 20459645
TRADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
CALR LRP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759 25351513
CALR LRP1 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759 25351513
PRKACA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12069755 19651622 11158305
MAP3K5 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TRADD MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1B MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TAB1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20060931 21614932 12738796 11274345 18855897
MAP3K5 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 20213747 12556535 19392652 18855897 17462996 8974401 18641653 23331499 23850759 12655147 21614932 21133840 12738796 21232017 15866172 24378531 15592525 12820963 11689443 25098452 26192618 11274345
SP1 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7702755 10669635 21419216 23784082 11853549 12388080 18779124 16740634 15869407 22009531 23500038 23834335 12083788 11560779 15706661 11912921
PRKACA STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11853558 17482548 11297520 17482549 10642527
MAP3K5 TNFRSF1B â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
MAP3K5 TNFRSF1B â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TNFRSF1B MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
DYRK2 KATNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19287380
DYRK2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20831597 22307329
CALM3 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9952395 8625412 12379661 9728925
CALM3 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 3006921 17353931 20668654
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
EPHA4 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12084815 23331499 16713569
FYN PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7515100 1334406 16713569 1652056
FYN GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9670010 10458595 10195142 12932824 9892651 19834457 16713569 11677266
FYN FCGR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8756631 17474147 10704309
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
GNAS ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9228084 9748257 9268375 21406690
HRAS RAF1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RAF1 HRAS â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 HRAS â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
JUN RAF1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
RAF1 HRAS â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8911690 8530446 10848612 8035810 9099670 19805522 7730360
PRKACA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19007248 11971957 20166139 18767875 20230923 9001246 10576742 23331499 20068231 7935389 18669648 18691976 9922370 15664191 19651622 12801936 9091312 10862777 9710607 11997508
HRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 147.0 1.0 Omnipath 17145710 18273062 9523700 1639773 8601312 19595761 20133694 11032808 9154803 10882715 14654780 1996324 19222999 16301319 11948414 8530446 7969158 11313862 9150145 20080631 1990291 12750173 15031288 12932319 9665134 8805624 8340422 1386920 23331499 16916524 16041367 23180781 18988627 20178605 15688026 15664191 22169110 11733498 7862125 8180183 19063885 12391160 9144171 8035810 9020159 14724584 19696784 21779497 9261098 12173045 12620389 8628317 19914712 1708096 19933846 26721396 7730360 10205168 8332187 16803888 18775988 12917261 9099670 10545207 25684575 8670882 10783161 12379659 10887184 17569879 21071413 8332195 7523381 10531446 24929361 8503013 16093354 19541618 10369681 8911690 18073111 11136732 10922060 7760835 11134016
NRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9867809 12750173 12932319 9001246 9665134 8805624 1386920 1639773 8340422 8601312 19595761 23331499 21071413 8332195 10531446 10882715 7811320 1996324 18988627 21779497 8636091 8503013 7766599 16093354 19541618 8180183 1708096 19933846 32296183 9525741 8876196 11136732 10205168 21478863 7760835 18775988 12917261 11134016 18641128 20080631 9488663 1990291
PIK3R2 HRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
SP1 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8106522 8208618 3012774 11559711 21931711 8027084 1776841
HRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9069260 9727023 17145710 10922060 11136978 21779497
CSNK1D AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21316585 12000790
SP1 TINF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21731707 9399940
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18163434 19751824 16264271 20847229 7969116 8413214 10772826 10567637
MAPK9 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 17143273 17145710 17637567 12584171 20506250 11948398 15378002 16824735 9687508 8654373 20028971 12788955 9305638 15302935 26091349 33822843 18362184 17875713 16393692 9405416 17570479 1922387 18252863 25561726 7737130 10490605 17189706 11896587 34408980 11274345 20178741 8525045 16076903 7992057 19527717 7600582 17215518 8985011 11801649 19118012 11278395 8001819 8137421 19436832 16533805 8945519 12881422 9315636 10385525 12093796 14523011 19910486 15212693 8157646 12040039 11562357
MAPK10 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17143273 20506250 16824735 8654373 20028971 16007099 21988832 12167088 16393692 1922387 16076903 22327296 19527717 21757544 19436832 17670986 14523011 11274345 20395206 11562357
NDUFS5 NDUFA11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFA11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFA11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFA11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA2 NDUFA11 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFA11 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA2 NDUFA11 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFA11 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFA11 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS5 NDUFA11 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFA2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA2 NDUFS5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFA2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA2 NDUFS5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFS5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFS4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFB6 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759
NDUFB4 NDUFB6 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12601012 12667446 15186778 15526035 15807660 16200211 16218961 16246152 17344420 18485875 19131594 20025615 20816094 23850759
NDUFB4 NDUFS4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB4 NDUFS5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFS5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFS4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFS5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB6 NDUFS4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFS5 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS4 NDUFS5 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PINK1 MFN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 29971063 24328763 29674596 25132912 28190190 26992930 26611876
PINK1 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 93.0 1.0 Omnipath 25216678 27906179 19229105 26162776 25847540 29183391 26116755 33730565 26707701 25474007 25365205 25548534 25595529 29372317 24184327 25611507 22724072 20398440 26471730 28626500 29422536 27453777 24962176 24751536 26631732 22944659 17052189 25375667 25088558 33827825 27554669 24357652 24647965 24671417 29660402 30063295 27528605 23256036 29883688 23933751 23670163 23319602 25505445 25849928 23754282 20418918 19966284 25697646 32983119 30012094 34166935 29809156 24901221 28323427 25284222 29689231 30404819 19358826 19880420 20126261 26254304 20966070 29950828 20798600 29991771 24660806 30290272 25611391 25712550 29899409 28920079 25591737 29475881 29337137
TRADD MAP3K5 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRADD MAP3K5 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRADD MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRADD MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP3K5 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
MAP3K5 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 11029458 16709866 12655147 21614932 12738796 11274345 19880523 21771788 19805025 8974401 19920149 18855897
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
SP1 CTSL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11742542 14563703
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
SP1 ITGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8887648 20090957 11238113 11313353
MAPK9 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9130707 20506250 8846788 8654373 20028971 17875713 16393692 26538579 11145955 11309409 8887554 26370088 8548291 15782123 8262053 19436832 12665513 12947314 11274345
MAPK10 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19436832 20506250 16393692 8654373 20028971 11274345
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AKT3 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20016067 17680028 20214616 17688959 20398329 16537363 17052453 19575820
PRKACA GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12399457
PRKACA KCNJ3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19151997
PRKACA TH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12421349 7901013 11359875 2874140
PRKACA DYNLRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23333499
GNAQ PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11753430 1309799 12193606 16754659 8245028 8387502 1322796 1846707
HDAC6 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21220424 21847094 17643370
MAPK10 KIF5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24953741 26794516 19525941
CAMK2A TH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 7901013 1347949 11359875 24055376 1680128 16626642 34031189 17570479 34238765 6150037 11502746 12421349
ARRB2 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19782076 11090355 18408005 11356842
PIK3CG TPM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16094730
ESR2 NRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18048642 21233487
PIK3R2 NRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HSPA1A DNAJA4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
CTBP1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12711682
MAPK9 MFN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22748923
KATNB1 KATNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9568719 26929214 10751153 26496610 16203747
KATNA1 KATNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9568719 26929214 10751153 26496610 16203747
PRKN SNCAIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11590439 15894486 20418918 16049031 21590270 16096643 15603737 15944382 20089136