Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
ATM HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
FOXO1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15817464 15632117
BAX GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0912742107 20080742
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
RNF7 CUL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DDB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SKP1 FZR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791267 10023660
ANAPC5 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RNF31 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24469399 21455180
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
RFWD3 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0912094107 20173098
RFWD3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20173098
UBC OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11689694 5214752
UBA1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
AIRE PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CDC27 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK8 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033842 16982329
PIK3R1 SEPTIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17024187 5219199
PIK3R1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7642542 16982329
RNF111 SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008162 10465784
UBTD1 TRIM39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM39 UBE2D4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM39 TRIM17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ATF4 XIAP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
ATF4 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16931790
UBE2D2 RNF5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
DAZAP2 RNF115 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
UBE2D4 MID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CSNK2B SEC63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23287549
NFKB1 SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23335796
POLR2E CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP3K5 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INCA1 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBB MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA8 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFKBIA UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219675 17318178
MAP3K1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689078 16681998
RBCK1 RNF31 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBC DTX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17028573 5219205
ITCH DTX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17028573 5219205
ITCH DTX1 â—¼   COLOCALIZATION 2.0 0.8 intact 17028573 5219205
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SSR4 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218828 16845370
GSK3B MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12584189
UBC SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6504434 17936276
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC AIRE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
LNX1 SRC â—¼   COLOCALIZATION 2.0 0.8 intact 6504434 17936276
UBC SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
UBC MKRN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7298683 19536131
PDIA3 ERO1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17170699 5219449
ERO1A PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
ERN1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6542966 18369366
RING1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
UBC RCHY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220017 17568776
LNX1 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PHC1 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ANAPC2 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ARPC1B UBTD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SIAH1 PHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MYBL2 HSPA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8545114 9121772
PHC2 SFMBT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PHC2 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SFMBT1 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SSR2 SSR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 28218252 11964406
SSR4 SSR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 28218252 11964406
SSR3 SSR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DAZAP2 SEPTIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SSR2 SSR4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 28218252 11964406
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SEPTIN6 SEPTIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CBLB PIK3R1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CHFR UBE2D2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
RNF13 UBB â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RNF13 UBC â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RBX1 UBB â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 UBC â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HSP90AA1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CBLB UBB â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
OTUB1 TRAF6 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34591986 20622874 19996094
TRAF6 GSK3B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31594754 30711629 31754475 30806153
ARPC5 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
TRIM25 UBB â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
RLIM UBB â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
RNF38 UBB â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
RLIM UBC â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ITCH TRAF6 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
TRIM23 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
AMFR UBB â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
FBXW8 RBX1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
TRAF6 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 25499913
UBC MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 19166840 6823655
BIRC3 OTUB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23524849 30948266
SEC63 UFL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32807901 33957083
RAC1 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
ARPC5 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MKRN2 MKRN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 32460013
SAR1A SAR1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZNRF4 ERN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RING1 FBRS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
SAR1A SEC23B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TRIM25 UBE2D2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
RNF31 UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
LNX1 UBB â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
LNX1 UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
SSR3 SSR4 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CBL ITCH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
HERC2 BIRC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25476789 26186194
LCOR PHF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
TRAF6 UBC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 17703191 19820695 18239685
TRAF6 BIRC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20097753 24464131 23524849 29545793
BIRC3 UBA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23524849 30948266 25260751
UBC XIAP â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
BIRC8 XIAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RNF5 DERL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21594788 16901789 24019521
SKP1 RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
RAC1 TRAF7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 34215617
PDIA3 ERO1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17170699 20802462
PHC3 RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
PHC1 PHC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22325352 33961781 24981860
ERO1B ERO1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SKP1 UBB â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
SKP1 UBE2D2 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
RLIM UBE2D2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
SRC CBL â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6538879 18273061
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
NFKBIA IKBKG â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
IKBKG NFKBIA â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
SRC LNX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17936276
AMFR UBE2D2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
BIRC3 TRAF6 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ACTR2 CTTN â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
RNF31 IKBKG â—¼   POLYUBIQUITINATION ✅ + 0.84 0.84 Signor 24469399
ANAPC2 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SOCS3 CUL5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24438103 15601820 30166453 17135358
DDB1 PHF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23238014 29846670
UBC MDM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17290220 19166840 18566590 19098711
MDM2 ATF4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27264869 21988832
SIAH1 PHC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20471960 25416956 21516116 21988832
RING1 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
MDM2 UBB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RNF111 UBE2D2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
TRIM25 UBC â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
RNF38 UBC â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
UBA1 UBE2D4 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
TRIM23 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
TRAF6 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10635328 16189514 22447928 29545793
LNX1 UBE2D2 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MDM2 UBE2A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22083959 12640129
CHFR DTX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22493164 33961781 26186194
TRIM2 TRIM3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
SKP1 UBC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AMFR DERL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RCHY1 UBE2D2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HSP90AA1 HSPA1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TRIM8 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MID1 MID2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RNF4 UBE2D2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PHC1 PHC2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FBXW8 RBX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10531037 18498745 31343991 33961781 12481031 17205132 33504946
TRAF6 XIAP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 25241761 22493164 12048196
RAC1 XIAP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25301945 26279033 22117219
NFKBIA SKP1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RBCK1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
PCGF1 SKP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 26687479 27505670 32628469 27705803 22325352 33961781 24981860
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
SIAH1 PIAS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17533377 27485016
TNIP1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CUL7 SKP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBA1 UBE2A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
UBE2D2 XIAP â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CUL7 RBX1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
IKBKG RBCK1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
OTUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAP3K1 MAPK8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PARK2 UBE2D2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
FBXW8 CUL7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17332328 10531037 16142236 21572988 23029530 17998335 18498745 31343991 17205132 12481031 23045529 21946088
CUL7 SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10531037 17998335 27705803 31343991 33961781 12481031 23045529
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
UBE2D2 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8379996 22124327
PHC1 RING1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 9199346 27705803 22325352 33961781 24981860
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CUL7 FBXW8 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
TRAF6 UBTD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PHC3 RING1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ITCH UBC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
RNF13 UBE2D2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
SRC CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29899407 17094785 16713569 18273061 7782294 12941616 10829062 31120930 15135048 17141222 18996392 8635998 11994282 22203672 19861161 16636290
RBX1 CUL7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17332328 24793695 24793696
CUL7 RBX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10531037 16142236 25752541 31343991 33961781 12481031 33504946 16547496 23045529
FBXW8 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10531037 26087183 21572988 18498745 21946088 27705803 31343991 17205132 12481031 20596027 33961781 15070733 22388891
ANAPC2 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9811605 10500174
FZR1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9811605 10500174
RNF114 MAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
GSK3B MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055726 18505846
SOCS3 RBX1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18481982 9869640 19649319
RBX1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10230406 9859996 10066435
SOCS3 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18055217 16543409
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
ITCH DTX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17028573
NFKB1 TNIP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 21988832 19695220 35140242 33961781 25609649
SEC13 SAR1B â—¼   GTPASE_REACTION ✅ 3.0 0.9 Reactome 10982397 10825291 17316621
HSPA8 MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANAPC5 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
CDC27 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
SEC24B SAR1B â—¼   GTPASE_REACTION ✅ 3.0 0.9 Reactome 10982397 10825291 17316621
ERN1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18471544 27009865
PCGF1 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16943429 22493164 26687479 27505670 27705803 22325352 33961781 24981860
SEC63 SEC62 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23287549 10799540 16713569
PHC1 PHC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 16713569 22325352 33961781 15563468 24981860 9121482
FBXO4 SKP1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ITCH UBE2D2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
UBB UBE2D2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
TRIM50 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
TRIM50 UBTD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
IKBKG RNF31 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
PHC1 RING1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PCGF1 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
RNF115 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SMURF2 UBC â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PCGF1 RNF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ANAPC2 UBE2D2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
RNF5 UBTD1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
FBXW8 SKP1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PHC3 RNF2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
SEC23B SEC24B â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
IKBKG UBC â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
RNF5 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
UBE2D4 UBTD1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PIK3R1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5217342 15556646
RNF2 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
RING1 PHC2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22325352 24981860 15386022 27705803
SEC13 SEC23B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SEC13 SEC24B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TRIM23 UBE2D2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PHC2 RING1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FBXO6 SKP1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
RNF38 UBE2D2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
OTUB1 UBC â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
UBA1 UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CBLB UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ITCH DTX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17028573 18628966
SEC63 SEC62 â—¼   PHYSICAL_INTERACTION ✅ + 0.95 0.95 Signor 23287549
SEC62 SEC63 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PARK2 UBB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PCGF1 SKP1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CUL5 RBX1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31253590 18805092 10230407 11861641 14564014 25912140 19250909 30349055 15574593 22405651
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
RBX1 SKP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 12504025 12840033 12481031 26540345 11245432 29507117 10531037 16357137 30349055 15452136 12813041 23770852 29499133 12628165 11961546 29863914 33692209 27705803 33504946 12684064
ARPC3 ARPC5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23148219 26655834 22863883 33961781 24981860 26186194 22939629 26344197
PHC2 RNF2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CBLB UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RNF25 UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RNF31 UBE2D2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CBL UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARPC2 ARPC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 26655834 22863883 24981860 22939629 26344197
RNF31 RBCK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219147 17006537
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
AMFR UBC â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BIRC3 UBE2D2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL5 RNF7 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MDM2 UBE2D2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RNF31 UBC â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CUL5 RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RBX1 UBE2D2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
NFKB1 NFKBIA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CNOT4 UBE2D2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UBA1 UBC â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
ARPC2 ARPC3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 11805826 23148219 22863883 33961781 24981860 9230079 26186194 22939629 26344197
PHC1 RNF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
IKBKG NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL PIK3R1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 27486774 21490922 20932476 20188669 18583959 22435563 28626800 24957606 16497931 21872579 20932475 19917246 16965765 23063077
ATM TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20932475 21872579
ATM SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 27689990 15964794 11877377 17303408 19788416 16163361 27308327 23847781 18536714 12607003 15459660
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
ATM UFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30886146
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
MAPK8 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525785 18471544 16709574
GSK3B BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 29379583 27762303 15525785 20976235 26287183 17911107 16709574
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
CBL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 98.0 1.0 Omnipath 9092574 19190244 16289966 11406619 7642581 11133830 10358153 8941725 9234717 8612729 11157475 10620516 16713569 21203488 11418612 24113870 17635922 18374639 14530346 11526404 8662998 8995358 11030146 9890970 9541596 11042121 15581361 9890943 8080844 7791764 9178909 15107835 8995243 8695807 9988765 23109003 11944898 15556646 17237826 10025673 17722974 8621719 16135792 16107703 16219545 9461587 9160881 9414268 16982329 19861161 10514377 9918857 11087752 9092538 11994282 9259313 15790353 19531499 9174058 8702998 25814554 22315502 19380743 10918571 8896416
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
GSK3B FBXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18598945 21242966 19489726 17570479 21113395
SKP1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080
CDC27 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC27 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
FZR1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
NFKB1 HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17724475 21725609 23178297 23572150
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
NFKBIA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKB1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RNF31 IKBKG â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
MAP3K1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9008162 19666475 9689078 12221085
RBCK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
IKBKG NFKBIA â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
NFKB1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
TNIP1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 16684768 18212736 20010814
IKBKG NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 17145710 7862124 11087742 10602462 16818647 8657102 16965765 22435544 11064457 24369075 10880512 7739562 14743216 16319058 7878466 16126728 10329646 15836773 16177806 21217772 16153868 10195894 12514169 18617513 15371334 16493424 17706453 15145317 10723801 15870263 7796813 17468758 16603398 17965022 11830587
IKBKG NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
MAP3K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 25241761 15315965 12049732 24135036
MAPK3 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
MAPK3 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10537323 17081983 18088087 15144186 21079800 16964243 20444238
MDM2 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19805293 22056774 17290220
CBLB PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 11087752 21780115 10488096 19531499 11526404 10086340 15032589 23109003 22880054 9614102 17635922 10514377
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
PIK3R1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7629060 8034624 12086876 12515821
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
UBE2D2 RBX1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
NFKBIA RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
NFKB1 RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RBX1 SKP1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 SKP1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10066435 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258 9859996
TRAF6 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18292600 9774977 10523862 10921914 17724081 15310755
TRAF6 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 7862124 7739562 11087742 10195894 7796813 12514169 7878466 8657102 16493424 17965022
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
NFKB1 XIAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17435549 21725609 23178297 23572150
NFKB1 XIAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15041463 18223231 14739605 16157589 18978816 18761050 15756023 18566231 16453001
EIF2S1 ATF4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
CSNK2B RNF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11710515 10512750 12748192 12470599 16713569
CSNK2B NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10764587 16410802 14580335 9724653
SKP1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10066435 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258 9859996
NFKB1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 1829648 21725609 23178297 23572150 8096091
NFKB1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17876798 15499023 17709515 7775482 11744993 10454561 11060311 12885753 9250151
SRC NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 24216290 12432072 24637265 12429743 25671697 14991073 8797825 24101387 9792645
NFKB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 25609649 7862124 1340770 16210649 16970925 21719482 9738011 9865693 10497169 8657102 9572494 9315679 21988832 8887676 10329681 1829648 14743216 17003112 11313474 20558726 26496610 7867065 7891711 10837071 7831327 15836773 26186194 11571291 15214841 17561400 16846590 9566883 8096091 15371334 7479976 11020244 9426183 16493424 15145317 8631829 20237821 20980497 16513645 9597130 7479848 7739549 7628694 10655476
SKP1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17145710 9990852 14743216 10066435 9990853 9859996
UBE2D2 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10329681
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
RBCK1 RNF31 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RBCK1 RNF31 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
DTX1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15684388
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
MAP3K5 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17634293 20348951 15247305 21785467 12194869 12221076 18818208 18029441 19667122 21726807 16760468 21212517 19749799 26147002 25310587 33573023 26375285 16648474 15944157 7839144 12456653 25915038 26853469 21856198 31575661 10521505 25702873 19029119 20156337 16928747 15020250 20452983 15242986 18570871 16845370 20871632 21040800 27203743 19783996 21931634 23608534 21697492 25619840 26964622 12758252 16632641 28881794 17210579 34048499 20921231
RAC1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7600581 9487126 7992057 7600582 9733714 9305638
CDC42 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7600581 17161586 23109003 9487126 7601337 9305638
MAP3K1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12228228 9405400 25241761 10465784 15757900 15299005 14500727 21152872 26538579
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
RAC1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17251915 12213839 18423204 18426980 10592173 22252525 10930450
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
SRC CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 27603901 22823952 7680654 9748248 28522963 19419567 19690332 16497976 15592455 19413330 25077552 17389395 19534553 20068231 28769876 17570479 20708589 19273217 18491316 18669648 16162656 25682866 12522270 18088087 22761768 26142315 17287340 27009365 10921917 9683637 24465712 27758765 24675741 12601080 18707149 16212419 15169891 7519605 17016520 11389697
CDC42 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 12213839 25284480 18426980 10930450
ROCK1 PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25681442 22479341 18573880 29849894 25084196
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
NFKB1 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15955070 17079305 7799921 17496231 15699120 10074115 20855868 24656046 10848607 12077266 8035474 17785777 20048166 21209118 16125763 12005436 22427889 21343618
TNIP1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21988832 25609649 14743216 19695220
GSK3B NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 26999213 12871932 11425860 24618402 18669648 17693123
MAPK8 ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23435430 16469705 15358865 16446428
ANAPC2 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10922056 10500174
CDC27 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10922056 10500174
MAPK8 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
ARPC1B ARPC5 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
UBE2D2 TRIM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 18312418 12878161 19549727