Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAK1 RAF1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17097642 5219317
EIF4A2 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17353931
RAF1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30761125 27554335
RPS6KA5 RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216210 12628924
PDPK1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PABPC1 EIF4A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914856107 20133758
EIF4H EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11418588 19203580
EIF2S2 EIF4A1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
C11orf68 EIF4H â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
MCC CSNK1E â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 21900206 2001699 8089645
EIF2S3 EIF4A1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EIF2S2 EIF4G1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
EIF2S1 EIF4G1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
EIF2S1 EIF4A1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
EIF4B EIF4G1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
PABPC1 EIF4G1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 9857202 6548418
EIF4E PABPC1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
OTUB1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26752685 18954305
EIF4A1 EIF4A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PAK1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 9823899 12551923 10205168 9234708 11733498
RAF1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15520807 17462920 20363321
EIF2S1 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
EIF2S2 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
EIF2S3 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
EIF4A1 EIF4E â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
EIF1AX EIF2S3 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EIF4A2 EIF4G1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
EIF1AX EIF4A1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
EIF1AX EIF2S2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
MAP2K2 RAF1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EIF1AX EIF2S1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EIF4G1 EIF4A1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219000 16932749
EIF4E EIF4G1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EIF4G1 PABPC1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EIF4A1 EIF4G1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
IKBKE RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 28317833 12842894 16046471 20188669 15128824 17561400 17003035 30223576 15485852 10521409 15489227 15849198 16407239 26025205 15212693 12767944
PDPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11134074 21726627 21209852 10995762 23885116 26009991 26238471 10551809 25335797
PAK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 28007610 19421139 26333361 22096607 15849194 12952546 30197477 12551923 23162742 25733387 17097642 22105362 18465753 23331499 24924700 10801448 26257058 21917714 12719581 11376654 25843685 15664191 19165420 23576562 23506953 10205168 24505617 28415790 18775988 22983922 9234708 12952943 16129686 25472536 11733498 11948406 9823899 11897507
SYK PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9531509 20068231 12881490 17192257 15583006
EIF2S1 EIF4E â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF4E EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF4E EIF1AX â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF4E EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
PRKCA EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1911648 8662663 2355012 12897141 9155017 17570479 11723111 95301551 11463832 9878069
EIF4G1 EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 8521827 22509910 17689282 23665581 22586265 16648488 16467844 9372926 16541103 15361857 16720573 9418880 16281055 18955708 12071973 21191102 26186194 10753870 15153109 10600798 7651417 20212144
PRKCA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 1386920 23331499 9447975 8321321 12551925 8288587 7935389 12917261 9922370 15664191 93309588 1437148
RAF1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 7565670 12750173 18799465 16364241 11909642 19219045 21988832 23331499 15342917 8933152 9671314 8393135 9808624 8223433 16189514 18988627 18669648 19541618 16293107 10969079 10567369 8157000 11136732 11948414 7898932 9069260 18039929 19369195 8607979 10327068 17116858 24746704 12920017 16129686 19058874 15466214
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF4H â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S1 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S1 EIF4A2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S1 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF4H â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S2 EIF4A2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S2 EIF4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S2 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
RPS6KA5 RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
RELA FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10649441 18064631 10867646 22223884 12372417
RELA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10833420 20966071 16317091 7536741 16627481 16385502 10946302 19422386 22708120 23042817 19281832 10553096 10329958 11359843 7692229 16249517 10496926 7537851 16453001
RPS6KA5 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17145710 27768872 19197368 22187158 20204068 22216091 19706715 30240634 25241761 11931769 19910110 21791059 23536830 23485395 22312446 19789307 24705157 27009097 17255956 12628924
EIF4B EIF1AX â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF4B EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
PDPK1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15209375 11078882 10698939 9889098
PDPK1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15175348 15466476
EIF2S3 EIF4H â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S3 EIF4A2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S3 EIF4G1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF1AX EIF4H â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF1AX EIF4G1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF1AX EIF4A2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
PABPC1 EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19716330 17145710 16772376 12086624 9857202