Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSPA1A HSPA1B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HSPA1B PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
HIF1A HSPA1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19335985 18844219
HSF1 HSPA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9869631
MKRN1 TERC â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
ABCE1 PA2G4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ABL1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CD2AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 NEK8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23581475
AR AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 23689136
AHR IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19461128 16289099
AHR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15077192 10398686
AHR HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14973392 11174852
AHR HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2153080 18805402
AHR AIP â—¼   COLOCALIZATION 2.0 0.8 intact 6594475 16257957
AHR AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19815066 17392787
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
HSP90AB1 AIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19375531 7021854
AIP ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21984905
FKBP4 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR PPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18212046 20610535
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
FKBP4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19545546 15831525
AR DBI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17721441
AR FKBP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131019
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
TRAF6 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906941106 19955404
TP53 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BCR CFTR â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
PTGES3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
IRF1 CASP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10918594
PTGES3 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
STK11 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 34591612
CDC37 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CDC37 STK11 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A1 HIF1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17382325 5219810
ESR1 DBI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9122238 9738013
MKRN1 DKC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
EDF1 RPS12 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EGLN1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 0.8 0.8 mint 7987706 20840591
HIF1A EGLN1 â—¼   HYDROXYLATION ✅ 0.8 0.8 mint 5217229 15474027
EGLN1 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
TP53 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19416861 10082513
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
ESR1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 8625613
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
FKBP4 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 27462449 11751894
FKBP5 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NR3C1 FKBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18524780 12519866
STUB1 FKBP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
NR3C1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16303956 3611064
TP53 FRMD5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19139068
MKRN1 GAR1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
NR3C1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22160539 3018491
TP53 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23940366 9360971
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HSP90AB1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A PPP5C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
HIF1A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699159
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
TP53 HMGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547598 9472015
HSP90AB1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSF1 STIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22669480 20692357
NUDCD2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
NOD1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217878 16083881
HSP90AA1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1A PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
PPP5C HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
HSPA8 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPA1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPB1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 NDN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18950704
JAK3 IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
NR3C1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9510064 2159467
IRF1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12545159 15710386
IRF1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22182512 19056926
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
MKRN1 NHP2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
MKRN1 NOP10 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
MKRN1 WRAP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
MKRN1 PTGES3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15805468 20473778
TP53 NDN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713459 10347180
OTUB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
TP53 PPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
STIP1 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
PTGES3 ZC3H13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SERBP1 RAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RANBP1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12649209 5216249
RAN SPAG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STIP1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
UBE2L3 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
TP53 WRAP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19250907 21924287
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
ARPP19 PCNP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HIF1A HSP90AB1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
STUB1 UBE2D4 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
DENR PSMD9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CHMP4A CHMP5 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RAN UBE2I â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
NEDD8-MDP1 UBE2NL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ARPP19 SZRD1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
OTUB1 TRAF6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20622874 34591986 19996094
TP53 SMYD2 â—¼   ADP_RIBOSYLATION ✅ 0.81 0.81 mint 25609649
HSP90AB1 HSPA1A â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SMYD2 BTF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 24981860
VCAM1 CD2AP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RIPK4 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29435596
CFTR CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
STIP1 CFTR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20534503 31324722
CFTR FKBP8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
FKBP5 EGLN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31763849
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
ESR2 PCBP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 29509190
ESR2 RAN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21951318 29509190
VCAM1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ILK RAN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 23455922
VCAM1 PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PDCD6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PPIA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RAN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 STIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HSP90AB1 NR3C1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HSP90AA1 STK11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EIF4H SZRD1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CFTR BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17110338 15494376
PCBP1 CDC37 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
CFTR UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19233847 17110338
ESR2 UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33456993 25408199 17962381
HSPB1 HSF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25036637 19597476
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
PCBP1 MET â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PA2G4 RPS12 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
AIP HSP90AA1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PTGES3 TERT â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MAPT PRKACG â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NDN TP53 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
AHSA1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 22504172
FKBP5 AURKB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 32707033
IRAK1 CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15647277 32707033
ESR1 PA2G4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
FKBP5 ILK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 32707033
FLCN FNIP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DENR RPS12 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
AGO2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
OTUB1 UBE2V2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PA2G4 SERBP1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
FKBP4 NR3C1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CFTR AHSA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338 18556464
CDKL1 FKBP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
CFTR RAN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 17110338 31324722
CFTR HSPB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 23155000 26618866 17110338 26627832
CFTR PDIA4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
VHL EGLN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22286099 17986458 26215701
STK11 FKBP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25036637 20562859 25852190 14676191 28514442 32707033
HSP90AA1 PPID â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
NHP2 NOP10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PARK2 UBE2G1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TRAF6 UBE2L3 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
FKBP5 AGO2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25036637 29395067
AGO2 FKBP4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29395067 23741051
SMYD2 CDC37 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 17353931
CFTR PDCD6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31324722 17110338
EDF1 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 31527615
NAA10 HIF1A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16638120 30237125 16511565 16288748
VHL PDCD5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24469044 17353931
RANBP1 UBE2L3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
FKBP5 MAPT â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ESR1 FKBP5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27483141 9222609
ESR1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23403292 9222609
HSF1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11583998 9222609
FNIP1 FNIP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27353360 18403135
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGLN1 FKBP8 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FN1 VHL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HSP90AA1 HSPA1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AR STUB1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CFTR STUB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IRF1 STUB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CSNK1A1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HSP90AB1 MAPT â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
AHR AIP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CDC37 AURKB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 31586073 26186194 29568061 32707033
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ILK HSPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25852190 17353931
HSPA1A STIP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HSP90AA1 TERT â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AHR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
FKBP4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
AIP ARNT â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9111057 12065584 11259606
FES BCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8955135 7529874 10706130
FNIP2 FLCN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27353360 28656962 18403135 25126726 33137092
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
SMYD2 TP53 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MAPT STUB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
HSPA1B FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
ABL1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11420673 20841568
AHR AIP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9447995 18805402 17329248
AR DBI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 8634149
AR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 17522055 18687691
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799378 20610535
AR CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22038727 20610535 23554843
ESR2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19487281 14729654 23907131
HIF1A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19342889 20138114 19940121
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
ILK CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18252715
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
ESR2 CLU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
RAD23B DBI â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
WRAP53 DKC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26496610 25467444 25416818
FKBP8 EGLN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21559462 19147576 19546213 23413029 27770548 31763849 24711448 32877691 17353276
HIF1A EGLN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26611735 23413029 16511565 16155211 20812988 22946054 27563096 33550096 18264140 16407130 20840591 24681946 31763849 15474027 17069766 20724477 34007068 25974097 29279301 15721254 17442832 25361009 17353276 19604478 18063574
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
JAK3 FES â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11160325
HSPA1A FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
STIP1 FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
HSPA8 FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSP90AA1 SMYD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22028380 18065756
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
HSPA1A NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21730050 24949977 12093808
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
HSPA8 MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
MAP2K7 MAPK8 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16186825 9162092 17875933
MKRN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19536131
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
PPP5C NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19586900
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
TERT TCF7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
VHL UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20844582 24002598 20300531
UBE2L3 UBE2V2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PTGES3 STIP1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
TRAF6 IRAK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18347055
HSF1 HSPA1A â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSPA1A STUB1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
TP53 UBE3A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
HSP90AA1 NR3C1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
UBE2L3 UBE3A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
PFDN5 PFDN6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
HSP90AA1 HSPA1B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
EGLN1 HIF1A â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
HSP90AB1 PTGES3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
HMGB1 TP53 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
RPS12 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ARNT SIM2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
IRAK1 TRAF6 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
RAN RANBP1 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
ABCE1 RPS12 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
FLCN FNIP2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
AHSA1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AIP AHR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10986286 11013261 16257957 7961671 16582008 9837941 9111057 9083006 12065584
HIF1A ARNT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12391259 10085255 16954218 7836384 17916562 26496610 8663540 34592152 14764593 20603618 14668441 21512126 11606485 26350169 9079689 24056783 19845609 27684187 11782478 19168635 23363003 26160453 28628118 15850782 17197389 21620138 15833858 23086815 24434214 20458141 18024476 23458834 12810720 28514442 15347669 9704006 27320910 20562859 11829741 15031145 21435239 20049704 15479785 20932347 12393189 11025203 16861921 9159130 10671489 16520375 15615775 17213817 28205554 23796364 15319539 11593383 19251694 20699359
MAP2K7 MAPK8 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
STUB1 UBE2N â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARNT AHR â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10619402 33961781 7628454 11768231 19390533 22138065 10395741 26350169 20006590 10617682 31675361 11259609 23477502 17392787 12139968 9887096 8631989 28514442 9704006 8065341 18096572 8621524 7488247 8619634 11025203 10671489 11551916 8384309 12024042 19380484
HSPA8 STIP1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GAR1 NHP2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GAR1 NOP10 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARK2 UBE2L3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NUTF2 RAN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HSPA1B DNAJC7 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
HSF1 HSPA1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21932106 24041570 21085490 19336471 20692357 11423545 18434628
TERC PTGES3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC NHP2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC PTGES3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC WRAP53 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC NOP10 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC DKC1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC NOP10 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC WRAP53 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC GAR1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC NHP2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC DKC1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
TERC GAR1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
AR ABCE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
ABL1 AHSA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26235616 27515256 29127155 26693507
ABL1 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20841568 17892306
ABL1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9407116 10405761 12522270 11780146 8622703 9178913 1712671 12124177 7529874 9467953 8955135 20841568 8112292 16912036 12543778 11376433
ABL1 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11278340 17474147 9346925
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10837221 20841568
ABL1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9826708 12766170 9391119 9242692 10506185 8547236 10069803 7687741 10490849 11741535 21777671 8906793 12475979 9444958 7513258 7961992 15475459 9252406 7838524 7731718 8662889 7708691
ABL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17254966 17908796 22276948 16195327
ABL1 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20861316 11113114 12408982
RAN AGO2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22064859 9214382 18842624 24596094 23150874 23882114 24388755 15643423 19167051
AHR TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17070097 15111621 11191113 20478272
AIP AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 9111057 10986286 11013261 16257957 9083006 16582008 12065584 9837941 7961671
HSP90AA1 AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9083006 9390191 7961671 8089152
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
AHSA1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12020745 20610535 14684616 18451309
AR THRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14521927 21055159 20610535
AR FKBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15821585 19433513 20048054 21809344 11867260 16210365 20610535 17142810
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
RAN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10400640 16713569 18565325
HSPB1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19767773 17974989
CASP3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8626669 9535906 16713569 9208847
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
CASP7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9535906 16713569
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
PA2G4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 15583694 9565586 12165860
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
SIM2 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14701734 11782478 9271372 9020169
CSNK2A1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16129408 18669648
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
BCKDK DLD â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22956686 15166214 24449431 15576032
FES BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 9407116 12522270 10405761 8622703 28819864 9178913 15302586 7529874 16497976 8955135 12124177
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
GZMB CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19254476 17179148 19103589 17283187 16495481 8700869 9694885 12745270 15569669 9233763 16415351 8755496 11696597
CASP3 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11274152 10672017
CASP3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12888622 16606369 22535953 11162250
GZMB CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19103589 17283187 15569669 15650747 8631895 21042704
CSNK2A1 CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 26755559 18566753 20068231 15082798 18922470 19413330 12930845 27105117
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
DYRK1B CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26307683 15010468 15546868 22711815 19887899 25476896 18818203 18636226 23528858
CSNK2A1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21930781 17289674
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
CSNK1A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10606744 9765199 20041275 11709713 18246126 27681874 10951572 29793495 10734067 11875057 10747897 10673501 11883897 11551930
CSNK1G2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10606744 11709713 10951572 10734067 11551930 10747897 10673501 11883897
CSNK2A1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
CSNK2A1 FKBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9405642
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12659875 15302935
CSNK2A1 UBE2R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12037680 18669648
CSNK2A1 PTGES3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17081983 15040786 18088087 18166671 16094384
CSNK2A1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15822905 17081983 16565220 18088087 29854279 2492519 34359868 25995454 1956339 16094384 15581363 18591256 16964243 92065884 15302935
CSNK2A1 PDCD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26077467 19616514 28051100
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
PTGES3 DKC1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 WRAP53 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 NHP2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 GAR1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 NOP10 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 DKC1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 WRAP53 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 GAR1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 NHP2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DKC1 NOP10 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
DLD PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
HSPA1A DNAJC7 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
HIF1A EGLN1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23487784 12839937 22075993 20574527 15563275 19628018 18072750 24558194 22451659 16157596
HIF1A EGLN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19604478 20840591 16511565 23413029 12351678 15474027 22946054 15652751 16407130 25361009 31763849 32755251 16391536 15721254 20724477 24145445 17353276 18264140 26611735
IRF1 EIF2AK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7543195 8622878 9333018
EIF2AK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17451862 16083285 1088347 10082513 10348343 10884347 16552184 9315650 9737981 19413330 16713569 10747897
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21411498 12122114 21693539 18519947 16690106 10805720 19360348 23409030 18754863
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12122114 10805720
NHP2 GAR1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NOP10 GAR1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 GAR1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
GAR1 WRAP53 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NHP2 GAR1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 GAR1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NOP10 GAR1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
GAR1 WRAP53 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
THRA GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12878587 3313046 8392063 8663468 3475698 9259323 3466175 1584227 21997736 8469235 2033067
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
IFNG HIF1A â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18754863 15048086 17699105 16961934
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
HIF1A MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099863 17028975
NAA10 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16288748 16511565 16638120 18593917 12464182
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
HMGB1 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
HMGB1 IRAK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
IFNG HMGB1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
TP53 HMGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
HMGB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
HSF1 HSPA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9699716 21932106 16460681 2674689 16012946 24041570 1508207 22797943 9011567 1717345 17897941 20692357 23212905 23874968
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413
HSF1 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21932106 24384723 15221402 20185824 20817212
MAPK8 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19651622 17081983 10747973 20166139 18767875 20068231 18669648
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
HSP90AA1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 16131566 8089152 10903152 26804907 31467278 8645634 15916966 24949977 21511880 19875381 9334248 12093808 16189514 20195357 24462205 10066374 14987994 8898375 8621522 8139547
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
TRAF6 IRAK1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
IRAK1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 10346818 17145710 17785851 16024789 14625308 11259596 10383454 18234474 9374458 11287640 23244239 21220427 11518704 19166926 16951367 15894263 10747026 35926385 18056395 12566447 12496252 22447928 12242293 8837778 10920205 11960013 19716405 24735611 20043910 24434549 17785432 11397809 18347055 22033459 12140561 23381138 17197697
TP53 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15509808 9806359 12732645 11350897
MAP2K7 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 12821118 10713157 11489946 17145710 9362518 13130464 18855897 19690332 95141073 24975362 23331499 7839144 21071413 18362184 11062067 21614932 15911620 12738796 18436711 11389443 10506143 11242024 11847100 18669648 16153436 15725726 25241761 18691976 14523011 25284480 16076903 17192257 11390361 15755722 16533805 19369195 9312068 9207092 9733513 12758252 12624093 15212693 11274345
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
PRKCZ MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962008 8702918 18667433 17646398
NOD1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17965022 17947236 11463746 17186025
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAPK8 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12351702 18337589 9482836 9199329 18669648
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 34342183 17314187 33557920 15312816 17761554 33762974 33842885 12614922 15136685 17270732 15228592 28758999 34385305 8506352 15994305
PPP5C MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15546861 12435421 14690518 1330687 16262633
PRKCZ MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
NDN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24722188 10347180 16713569 23785149
PTGES3 NHP2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NOP10 NHP2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NHP2 WRAP53 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 NHP2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NOP10 NHP2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NHP2 WRAP53 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 NOP10 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NOP10 WRAP53 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 NOP10 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NOP10 WRAP53 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
TP53 PPM1D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18333294 19015127 11101524 22405851 20093361
PPM1D TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15870257 17936559 23666059 28903382
PRKCZ STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11853558 18250273 19414597 16407220 18321849
PTGES3 WRAP53 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 STUB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTGES3 STUB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTGES3 WRAP53 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
RANBP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 11832950 12649209 9111043 10811801 7603572 9315840 20805321 7891706
STK11 SIK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19369195 22588126 14976552
SMYD2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25609649 21782458 17805299 18065756 17108971
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
TP53 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15656906 12807729 15067344 15734740 11064449 15262117 16234237 10778946 15371422 22496369 18754863 19649288 19787269
UBE3A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 23040663 7724550 9450543 16713569 16493710 15001357 17131388 9143503 19364824 31971989 11027293 9688277 9369221 1661671 7708685 12620801 8090726 8380895 26789255
WRAP53 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19571673 19250907 19918835
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
UBE2I UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15340381 12820959 18997815 15668399 18298802
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368
PIF1 FN1 â—¼   KO_UP_REGULATES ✅ + 2.37 2.37 PKG 28854368