Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BCL6 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22422878 19487462
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
WNK1 OXSR1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16832045 0604607103
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
OXSR1 WNK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
KLHL3 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8427680 23665031
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
KLHL2 KLHL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32296183 33961781
OXSR1 WNK4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
KLHL2 WNK4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23838290 24641320
CUL3 KLHL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 23838290 33961781 21145461
EPS15 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 19380743
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
OXSR1 WNK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17721439 16832045
NEDD4L SGK1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
KLHL3 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 23576762 23387299 25416956 23838290 26100637 23665031 23573258 25502805 25250572 30819806 33961781 26286618 23453970
KLHL3 WNK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25313067 23576762 23838290 23665031 23962426 26435498 26349538 26286618 23453970 24641320
KLHL3 WNK4 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CUL3 KLHL3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
SGK1 WNK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27517916 23054253 28493961 17360471 23673010 19706464 29352074 21248166 26491696 25805816 24535442
SGK1 NEDD4L â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 47.0 1.0 Omnipath 20621254 20166139 18767875 23589291 20230923 12911626 11742982 19413330 19664995 15586017 20068231 17570479 16189514 27517916 15140763 18669648 12729930 20730100 18691976 19651622 15328345 22301619 15677482
WNK1 OXSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 25389294 17190791 29581290 35044719 18270262 24555568 27050278 16083423 16832045 23026752 17721439 24191005
OXSR1 SLC12A3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18270262 30248150 21164023
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27053161 16107690 20101202 8206977 26680303
AKT1 WNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21355052 16081417 14611643 22119528
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
WNK1 STK39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18270262 18088087 16083423 16263722 17190791
WNK4 STK39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15930150 27942049 24097229 16990453 16083423 20463172 19633012
STK39 SLC12A3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21907141 21423148 18270262 25651566 26728390 20091762 30248150
WNK4 SLC12A3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22342722 27942049 28274929 12515852