Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RACK1 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MEF2D CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24390737 24279793
MEF2D MYH10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15728583
RPL8 MINDY3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
CUL1 UBE2M â—¼   NEDDYLATION ✅ 2.0 0.8 intact 17914462 6175264
UBE2M CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17439941
JUND APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
COPS6 BTBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CCNA1 CDKN1A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCNA1 CDKN1B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SHANK3 COPS6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 FBXO7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
EPRS1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMAD4 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259615
AHR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12203118 24431146
AHR VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17413038 19182260
AHR MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19755661 15075337
AHR CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15077192 10398686
AHR CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17070097 15111621
HNRNPD ANKRD12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APBB3 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
HSPA8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UCHL1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RANBP9 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDIA6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP2K2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
RPL7A ASNS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
STAT3 BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16732314 16293640
BIRC5 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EP300 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20660371 19102934
STAT3 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393476
RPL27A CAND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBE2I CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SKP1 CDC20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791267 10023660
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
TGFB1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23741479 12058028
SMARCA4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414052
RPL27A CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRAF2 CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAX CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313917 18393360
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
EEF1A2 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH10 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
MAP3K11 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10713178
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
COPS2 GFER â—¼   COLOCALIZATION 2.0 0.8 intact 5217148 15304329
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
COPS5 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24043623
COPS6 EDN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GFER COPS8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217148 15304329
PARP1 CUL4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
DCAF4 DCAF4L1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
DDA1 RBM39 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
DNAJA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10432218 18414489
EEF1A2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
SMAD4 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14741200
STAT3 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
TXN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19737086
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ETF1 RPL7A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPS24 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL30 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPS15 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL27A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL19 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SKP1 FBXL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HNRNPA0 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
HNRNPA2B1 SMARCA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPA2B1 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBE2I HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PTBP1 HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNRPA HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH10 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K7 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219785 17363973
SMAD7 KRT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23475202 17499880
PLOD1 LRRC47 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LRRC47 RPS16 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
LRRC47 RPS17 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
LRRC47 RPS15 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
LRRC47 RPS24 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UCHL1 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STAT3 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22108192
SNRPA PTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RPL13 SRP14 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPL23 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS15 SRP14 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPS17 SRP14 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPS24 SRP14 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SLC25A5 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMAD7 TGFB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10519551 19758997
SMAD7 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15855641 20631490
TGFB1 VTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11796824 16189514
TUBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL13 RPL19 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
LARP4B RACK1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
COPS2 CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
COPS8 NEDD8 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ETF1 RPS17 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ETF1 RPS16 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ETF1 RPL13 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ETF1 RPL23 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RPL5 RPS24 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BTBD2 COPS2 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RPL19 RPS16 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DDB2 FLOT1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
RPL30 RPS24 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL13 RPL8 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ETF1 RPL8 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
RPL27A RPS24 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPS16 RPS24 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL27A RPL5 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
COPS5 CRBN â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
RPS16 SRP14 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
HNRNPC SAFB2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA2B1 HNRNPC â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL13 RPL30 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CDT1 CUL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30018425 12840033
CUL1 CARM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34480022 21145461
CUL1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 9663463
CUL2 FEM1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
CUL4A SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22474075 21145461
SNX9 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 ASPH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
CAND1 RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 21145461
CDK2 UCHL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21319273 23543736
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
CUL4B RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 28302793
CUL4B SFPQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 34026424
CUL5 FEM1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SKP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
SF3B1 SRSF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
SIAH1 STAT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27871173 21988832
RPL23 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL30 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL5 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL7A SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL30 RPS16 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RPL19 RPL5 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TUBB TUBB1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RPL27A SRP14 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RPL8 SRP14 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RPL7A RPS24 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPL43 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
DDB2 UBE2H â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
RPL8 RPS24 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDT1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15138268 15004027 31160578 14993212
KCTD6 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27152988
DDA1 DDB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 20562859
ESR1 PDIA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
RPL5 RPS16 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA2B1 SAFB2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MRPL11 MRPS22 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CUL1 FBXO11 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCNA1 CDT1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RPL19 SRP14 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL3 KLHL13 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RPL27A RPL7A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CDKN1B CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CENPT CENPW â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
RPL19 RPL8 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CUL4A CDT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17079684 14578910 15448697
ESR1 CIRBP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
PARP1 DDB2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
HNRNPL SAFB2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CUL1 FBXO9 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RPL5 RPL8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RPL30 RPL5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RPL27A RPL8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SAFB2 SFPQ â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MEF2D EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10825153 11096067 10933397
NEDD8 AHR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12215427
CAND1 SKP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12504026 29499133 21145461
DET1 CUL4B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 16949367 31973889
ESR1 RTCB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31527615 19805454 20348541
SMAD4 MAX â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 12551947
DENR RPS16 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CUL4B DDA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
RPL30 RPL7A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
CUL3 DHX15 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
CUL3 PDIA6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
RPL19 RPL7A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
DENR RPS17 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HNRNPD HNRNPU â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
RPL13 RPL7A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RPL13 RPL5 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CUL3 UBE2M â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
RPL7A RPL8 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CUL4A DDA1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CARD11 MAP3K7 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
HNRNPC HNRNPL â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
CUL1 FBXO7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL1 CDK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 21145461 26186194 9636170 28514442
CUL3 BTBD2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32296183 17543862 21145461 19995937 19295130
CDK2 CDC20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23455922 26811472 25852190 28514442
COPS6 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS8 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL3 KCTD6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FEM1B CUL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 18187417 33961781 21145461
DET1 DDA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 19295130 17452440
CUL1 FBXL5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
FOSB JUND â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DENR RPS15 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DENR RPS24 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PRPF4 SNRPA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDKN1A STAT3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CHUK MAP3K7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
COPS2 DDB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RPL7A RPS16 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS8 CRBN â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HNRNPA2B1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
BTBD2 COPS5 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK2 SKP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MAP3K7 TRAF2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SMAD4 SMAD7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HNRNPC SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPD PTBP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
COPS6 CRBN â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HNRNPL PTBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IKBKB TRAF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTBP1 SNRPA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FBXO46 SKP1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
DET1 CUL4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16964240 16949367 14739464 17452440 28514442
AHR EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17392787 21988832 10999956
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CHUK TRAF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DCAF4 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28446751 21145461 26496610 32140073 16949367 30945288 28514442 31973889
DDA1 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 26496610 16949367 19295130 31973889
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDKN1B COPS5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS2 NEDD8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CARM1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
COPS8 CUL4A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CUL4A CRBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20223979 26990986 24292623 27294876 16964240 21145461 24292625 27142104 27029275 32235678 25860244 32132601 26231201 23983124 28514442 31973889
DHX15 SF3A3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29021621 26344197
SFPQ SNRPA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17507659 9848648 34133714 21566083
COPS8 CUL4B â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 DDB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK2 CDT1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CDK2 CDKN1C â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
IKBKB MAP3K7 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CCNA1 CDKN1B â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
COPS2 CUL4A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
EP300 MEF2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10825153 11796223 11096067
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL4A CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12504026 16964240 21145461 12504025 27203177 21249194 18606781 17079684 22405651 15448697 19295130 31973889 22474075 12609982
AP1B1 ATM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9707615 10608806
SIAH1 APC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11389840 25241761 16713569
BRE BRCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20656689 17353931 19615732 19261748 30755420 14636569 19261746 21282113 20032457 19261749
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
CAND1 SKP1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
MAP3K7 CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17158449 15327770 10882101
IKBKB CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
CHUK CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
CDT1 CDK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23455922 14993212 26496610 15855168 31160578 15004027
COPS6 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KLHL23 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A S100A8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SKP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16376880 25241761
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
COPS5 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16410250
NEDD8 CUL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 24654937 33961781 18274552 10597293 21119685 21145461 23201271 24076655 18247557 28522566 22405651 31253590 28514442 20847044
EPO STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24705157 25728669 12763138
RBM39 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15694343 11704680 33731348 21182205
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
ESR1 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17311863
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
PLK1 FBXL5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FBXO7 SKP1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RAD9A HUS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26088138 14624239 14681455 12628935 9872989 11907025 32296183 10777662 10852904 19464297 11994305 28514442 16189514 15314187 11340080 10359610 26186194 14611806
TXN PRDX2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 21385867 10514471 17519234
SFPQ PTBP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8449401 15975576 17507659 16713569 10653975 11514619
SMAD7 SMAD4 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11279127 15265520 23784029
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
COPS8 CUL2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
COPS2 CUL1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
NEDD8 SKP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
RPL5 RPL7A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
MRPL43 RPL23 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MRPS15 RPL23 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
FBXO11 SKP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CDC20 CDK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
FBXO17 SKP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
UBE2M NEDD8 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 19713960 7294536
MRPS15 MRPS22 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
COPS2 CUL3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CCNA1 CDKN1A â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CDC20 CCNA1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 19477924 10679238
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
DHX15 SF3B1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
SNRPA SNRPD3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CDK2 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 17409098
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
FBXO9 SKP1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PRPF4 SF3A3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
PRPF4 SF3B1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
MRPL11 MRPS15 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
MRPL11 MRPL43 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SF3A3 SF3B1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CDKN1B CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 34591612
RAD9A RAD1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11907025 25091155 33961781 25602520 10777662 16189514 15314187 26088138 10852904 11340080 10359610 11994305 11572977 26186194 12628935 14611806 28514442 9872989
FBXL5 SKP1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BRCC3 BRE â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SF3B1 SNRPA â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NEDD8 UBE2M â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
COPS2 CUL2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
CUL1 UBE2M â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
DHX15 SNRPD3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PRPF4 SNRPD3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
DCUN1D1 UBE2M â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EEF2 RPLP2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL43 MRPS15 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL13 RPLP2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
COPS2 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
COPS6 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EEF2 RPL27A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL8 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL19 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL30 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS15 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL13 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL13 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL13 RPS24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL27A RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL27A RPS24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL30 RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL7A RPS17 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SF3A3 SNRPD3 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
EEF2 RPL7A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL23 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPS24 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL5 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPS16 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPS15 RPS24 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL5 RPS24 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HUS1 RAD9A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL19 RPS24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL5 RPS15 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPLP2 RPS24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SF3A3 SNRPA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL7A RPS24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS16 RPS24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS5 COPS8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RAD1 RAD9A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL7A RPLP2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPLP2 RPS17 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPLP2 RPS15 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13 RPL8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL19 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL19 RPS17 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL19 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27A RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL27A RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL30 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL30 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL30 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL5 RPLP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL7A RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL8 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL8 RPS15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL8 RPS17 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS17 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SF3B1 SNRPD3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 COPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL19 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23 RPLP2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23 RPS17 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS17 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPL8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL8 RPLP2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPLP2 RPS16 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS15 RPS16 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS15 RPS17 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL27A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL30 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL27A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL30 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL30 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPL30 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL27A RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPL8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL8 RPS16 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS16 RPS17 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 CDKN1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL13 RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23 RPL5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL30 RPL7A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL5 RPS16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RACK1 LARP4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 26186194 20573744 12388589 32296183
RACK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16382134 23331499
APC CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
UBE2M CUL1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
APC CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
UBE2M CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24949976 10713156 17914462 21247897 18805092 21946088 19245792 18826954
CUL1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15340381 15147722 12820959 12835716 11961546 11516665 15071497 15688063
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
ESR1 JUND â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
JUND TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19211927 16896927 21515915 10843986
UBE2M CUL4A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
CDKN1A CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12383116 25241761 8756624 29997244 16982699 7478582 10022926 32814053 15232106 16009130 16189514
CDKN1B CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15583032 29997244 7478582 10022926 18692475 32814053 16189514
ACTR1A DYNLL1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
APC NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
APC NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CHUK APC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11955436 11967263 12051714 12799363 23430059 7542250 8666229
APC NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
TGFB1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12867422 25241761 16189514 2119582
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
CDK2 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM SMC3 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM STK11 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11331603 11571274 11877377 12234250 12607003 15140942 15459660 15964794 16163361 17303408 18001824 18006705 20160076 23030059 23847781 9488723
ATM RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11278446 26658951 17570479 22453082 12709442 18669648
ATM SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 22369641 18442975 15964794 11877377 17303408 16163361 23847781 17570479 12607003 20501661 19906707 17525332 15459660
ATM SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 27689990 15964794 11877377 17303408 19788416 16163361 27308327 23847781 18536714 12607003 15459660
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11853558 25329316 12234250 12805220 18971907 20864035 29284117 21191146 17570479 20160076 25488815 25244018
STAT3 BCL3 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
BIRC5 CDC20 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
STAT3 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19880237 26512963 15184887 15469392 16651438 18242580 16397018 21344490 20826784 24431073 15077160 12393476 19284568 17880940 17533050 17932422 22984561
PLK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20427271 22560880 24091645 24069188 21148584 25169932
STK11 BRSK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23629625 18339622 14976552 16870137
SKP1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
CARM1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15731352 21988832 11997499 11701890 15616592 16923966 18280497
STAT3 CD274 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19088198 21268011 27141364
PLK1 CDC20 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
CDC20 SMC3 â—¼   UP_REGULATES ✅ 8.0 1.0 ACSN 12070128 15279786 17303408 17660363 18590585 21270334 23197039 7575488
CDK2 CDT1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDKN2A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
SKP1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7553852 23602568 16979657 9636170 26496610 25852190
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 125.0 1.0 Omnipath 26416244 20519948 19631451 16326706 17409098 15557281 9658399 23029392 22733130 17570479 26496610 23576547 12700233 9388487 10585280 27282251 27175940 15619620 25241761 15735731 9218599 9192873 17254966 15996662 9724724 11940657 18285702 22492278 23409140 18615582 12093740 22721951 15647383 9380407 17418410 16189514 17053782 17698606 25852190 10679394 17602833 9660939 12188931 15122251 10831586 25818643 22028818 21424700 12529437 15011833 12042314 11250701 11223033 23455922 8978686 16780593 21439954 15302935 19648963 14504289 9736735 10198259 16782892 11565035 21423803 16492801 9311993 12417722 17671428 21187893 15355997 28601655 10809788 10393546 15212693 10323868 26450989 23602568 18850315 12482975 9399644 15890360 9632134 17254967 26186194 20810788 20197382 15475007 12800980 17997402 12972555 15980415 24336329 26701207 25605247 26987798
CDK2 SF3B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15212693 12105215 17081983 30115685
SMAD4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10878024 9618481 9865717 11786386 9307274 24052079 12429655 10962574 10415848
STAT3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23178160 19372587 15286705 18320073 15063116 16923815 9694869 22328012 12438313 11773079 20654581 10023678 19329556 21184768 11114718
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
SMAD7 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10878024 15922743 20104486 12185267 15555279 11180003
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
SMAD4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 9618481 17550342 12545156 11013220 15155580 11074002
CDKN1A STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 25241761 16189514 10764767
UBE2M CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
SKP1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15340381 15147722 12820959 16209941 11516665 15071497 15688063
COPS5 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17145710 22350412 15688030 18926707 24671224 12082530 18202760
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
IKBKB CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21619050 20152798 29292732
RAD1 CDT1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 CDT1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CHUK SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
TRAF2 CHUK â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
CHUK MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
MAP3K7 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 14960582 16893890 15836773 33895773 12547194 25241761 24911653 2547194 9742107 18949366 11274345 20200282 20194509 10094049 18855897 10187861
TRAF2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15725726 12547194 11359906 25241761 20449947 9244310 16713569 23007157 10795740 24323043 19150425
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
COPS5 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14993265 12374795
COPS5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11818334 27060206 16713569 17583730 14993265 1818334 24078030
UBE2M CUL3 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 19617556 18826954 25349211 23912815 25314029 18206966 21940857 23201271 26906416 19250909 30610225 25531226
UBE2M CUL4B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 12408818 10887155 15831498 21269274
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ESR1 FOSB â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
ESR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16267616 12400015 17272396 18252963 18497067 10866309 19420388 19398483 16249470 14647449 15774498 12208749 10995484
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
HUS1 RAD1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 RAD1 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
TRAF2 IKBKB â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
IKBKB MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
TRAF2 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 27387502 15725726 12547194 11359906 25241761 20449947 16713569 18362886 23007157 10795740 21119000 19150425
MAP3K7 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 24911653 11129660 25195736 16006187 16260493 15502405 14530355 10779355 28159912 10094049 10837071 15836773 25659581 10195894 9689078 17363973 10807933 15214841 16186825 16493424 10022904 18316610 10187861 12547194 33895773 28475177 16301747 15691841 15620648 15327770 29748387 19632174 11460167 17965022
PLK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18957422 19202066
STAT3 IRF8 â—¼   DOWN_REGULATES ✅ - 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
MAP2K2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17142955 9305919 7719937 7568001 10602027 12681450 7719938 7544001 7528668
TRAF2 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
SMAD7 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12589052
TRAF2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12547194 20038579 14633987 14743216 17384642
STAT3 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21611796 19754268 19118090 16887796
STAT3 S100A8 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
UBE2M SKP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SMAD4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23184087 10944227 20797318 12622415 24625091 20631490 18505344
SMAD4 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10823886 15183844 10887185 19032343 10839991 16442497 10753944 10843994 15128733 10559222
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
TGFB1 SMAD7 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
SMAD7 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10887185 15855807 9886263 20631490 22656308 19214138 23633623 14600158 10753944 11912247 11385614 11180003 17928287 19010789 22496417 22841502 17074765 15496141 11448947
TGFB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 14718519 16474430 17934056 20519943 9335507 21900405 11133108 14557817 15548370 19920116
TYK2 STAT3 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
STAT3 VEGFA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 22076197 19880237 12824281 20232316 18320073 20482858 17557905 21354136 19020709 17937859 20880395 25101566 16007214 19284568 19336759 20236940 10744750 11960372 15688401 19082717 21344490 20939432 17533737 21733558 18021292 20720018 11744720 23104276 16540670 11960378 20043094 21278793 21418908 15665043 15735682 21172343 23756865 20052595 17169602 18184402 21731766 23911788 12545153 22313388 16899623 20709526 18408167
TYK2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29145629 21098725 12626585 10542297 23331499 15261459 8662928 30910759 23673666 14565860 12023369 30029643 14764663 18389480 23124025 25516297
STAT3 VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17987801 16716598 13130303 7768934 11528470 9278421
DDB2 ERBB2 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368