Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ACSL3 DDX42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
ELP1 BAG6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EZH2 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
HUWE1 RPL30 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SFN MPRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
RAD50 RANBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAE1 DDX24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SFN KIF5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN CGN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
RAP1B TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18434644 17624957
ATP1A1 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KTN1 KIF5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10913441 15316074
CLTCL1 HIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11517213 5214430
HIP1 CLTCL1 â—¼   COLOCALIZATION 2.0 0.8 intact 11517213 5214430
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
RAC1 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31871319 8769096
RAC1 KTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8769096
RAC1 CYFIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9417078 16189514
CDC42 KTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31871319 8769096
GNB1 GNAI2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7102203 16782902
TPI1 DDX24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAP1B DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PFN2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PSAT1 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H1-5 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SRP14 CLASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRIP13 LASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
H1-5 MAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DTX2 TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CHD4 EZH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
RPL32 SRP14 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DDX50 DDX21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
EZH2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
CUL3 MCM7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 26188516
CDC42 RAB1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
AP2S1 REPS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAC1 STOM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 27173435
RHOA IPO9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
LASP1 TRIP13 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 8153045 21516116
RPL30 SRP14 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
GNAS MAGED2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
AP2A2 DAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22323290 11247302
RCC2 RAC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25074804 12919680
RHOC RHOA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31871319 33961781 31980649
KTN1 CDC42 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9535835 31871319
EZH2 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28486105 28068325 24981860 26344197
IARS1 EPRS1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 10913161 5212831
EPRS1 IARS1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 10913161 5212831
IPO5 KPNB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
GNAI2 GNB4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
AP2M1 REPS1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
LSM4 SNRNP40 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
KTN1 RHOA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8769096 12773565 31871319 11162552 11689693
ALPP GEMIN4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CUL3 PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26949739
GNAI1 GNAI2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
NCBP1 RNF20 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AP2M1 REPS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743
PFKM PFKP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RAB1B RAE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 26186194 9437002
CDC42 RAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
RHOA ITPR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 12766172
RAP1B CDC42 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31871319 26344197
CSE1L KPNB1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
S1PR1 GNAI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 8626678
SART1 SNRNP40 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PSMD10 PSMD6 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CLTC HIP1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
DDX23 LSM4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CD44 TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22566907 23620508 23886063
CDC37 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
STAT1 DDX50 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MPRIP RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31871319 9199174 14506264
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
SCRIB TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
GNB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15782186 16189514 26186194
RANBP2 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9398662 10473610
EIF2S3 RPS14 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GNAI1 GNB4 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
KPNB1 RANBP2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PSMD10 PSMD12 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
HK1 RHOC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CKAP5 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HK1 RHOA â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
NCBP1 SART1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
PSMD10 PSMD14 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
SEC23A SEC31A â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
MCM4 MCM7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12364596 12694531 20808282 8631321 8798650 12207017 9099751 12614612 7601140 10748114 23764002 24299456 15232106 22939629 17296731 10567526 22540012 22863883 27173435 26344197
AP2S1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 26344197
DDX23 SNRNP200 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DDX23 SNRNP40 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GNAS GNB1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
DDX23 SART1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
RANBP2 RANGAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LSM4 SART1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
GNAI2 GNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EEF2 RPS14 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EEF2 RPL32 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL30 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MCM7 MCM6 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 22939629 12694531 12614612 20808282 16438930 26496610 12207017 23764002 27173435 17296731 9099751 26344197
LSM4 SNRNP200 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RPL32 RPS14 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
PSMD12 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPL30 RPL32 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 NCAPH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PSMD14 PSMD6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
POLR2A TCEA1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MCM6 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM4 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD12 PSMD14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SNRNP200 SNRNP40 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNAI1 GNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CLTCL1 AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
HMGB1 BAG6 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12646658 15802534 19931333 22842346 26618107 27048821 27192565
HRAS CDKN2A â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 7510700 7673236 8551221 9069260 9763606 9846483
EZH2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19954516 21572997 23289480 23826727
CDKN2A HUWE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 16915296 15989956
MCM7 MCM4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PRMT1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11257227 12171910
MCM4 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16902406 12694531 12364596 12614612 22939629 26496610 8798650 12207017 22863883 27173435 17296731 26344197
MCM4 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
AP2A2 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTCL1 AP2S1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
RHOA KTN1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7787244 11933159 8769096 9822636 8912005 11689693
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
RHOA KTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12773565 11689693 8769096 11162552
KPNB1 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
KPNB1 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
SART1 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
S1PR1 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 8626678 31160049
RANBP2 RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16204249 9019411 11854305 19526197 22464730 12192048 22194619 11709548 21518904
RAB6A PAFAH1B1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056