ABL1
|
NOTCH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
ABL1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10601328
19564926
|
ABL1
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18619508
23418320
|
APBB1
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
GRB2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
BAD
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NOTCH1
|
CD44
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10933396
15107403
|
MMP14
|
CD44
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11381077
21385940
|
ADAM10
|
CD44
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18971959
26284334
|
CSNK2A2
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10938077
|
ELAVL1
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17317627
|
ELAVL1
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18644987
|
JAK2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
PTPN6
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10660620
6671678
|
FYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
PEX13
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SPTA1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12700044
2809592
|
APP
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12485888
5215996
|
LCK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
GRB2
|
SPTAN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
TUBA1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17993263
15031289
|
GRB2
|
ITK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10636929
|
PSEN2
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
PSEN1
|
NOTCH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
22330899
22363130
|
CREB1
|
PSEN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11116137
|
CTNND1
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10208590
11226248
|
PSEN1
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10208590
11226248
|
PSMD4
|
PSMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
PLCG1
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6805619
9020117
|
LCK
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18173375
18759926
|
PXN
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15574420
14665621
|
PTPN11
|
SRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8288622
20308328
|
PTPN11
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26617336
|
PTPN11
|
NRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26617336
|
PTPN11
|
CTNNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16767162
|
SIRT1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22249256
21640770
|
SIRT1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
27776347
28583374
|
PDIA3
|
PACSIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CALM3
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
7755592
10456332
|
EGF
|
BTC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7565730
8617750
|
ITGB1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0807543105
19168626
|
JAK2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
CRKL
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
ITGB1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19168626
|
SNX33
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PDIA3
|
ITGB5
|
â—¼ DISULFIDE_BOND
|
✅
|
|
2.0
|
0.8
|
intact
|
17170699
5219449
|
SRC
|
ITGB5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19910644
10592173
|
ITGB5
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19910644
10592173
|
BECN1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BECN1
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BECN1
|
GAS7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22081109
8303868
|
RELA
|
BECN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19289499
19458474
|
YES1
|
CSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
YES1
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7685273
6730440
|
YES1
|
NGEF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15848799
11336673
|
ERBB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
PDGFRB
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10733900
6731185
|
GRIN2D
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DTX1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
CRK
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15308668
16000375
|
PDGFRB
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6730293
1330535
|
PDGFRB
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PDGFRB
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6730458
7692233
|
PDGFRB
|
GRAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7935391
23331499
|
PDGFRB
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
11172806
|
PDGFRB
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8657151
9484840
|
ITGB1
|
JAM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12070135
17525755
|
ITGB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ITGB1
|
CD63
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5218971
16917503
|
PDIA3
|
ITGB1
|
â—¼ DISULFIDE_BOND
|
✅
|
|
2.0
|
0.8
|
intact
|
17170699
5219449
|
PIK3R2
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
LCK
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
LCK
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221707
9341123
|
LCK
|
PTPN6
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8114715
7028063
|
PTPRF
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12496362
|
FYN
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
22043010
|
LCK
|
NGEF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15848799
11336673
|
GRAP2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11390650
11048639
|
PLCG1
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
200301131
14568990
6804839
|
PLCG1
|
INSR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
200301131
14568990
6804839
|
SRC
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15574420
14665621
|
SRC
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
PIK3R2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
FYN
|
CSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
FYN
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
FYN
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FYN
|
APH1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FYN
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FYN
|
FAS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17159908
5219434
|
FYN
|
NGEF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15848799
11336673
|
SLC25A5
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NCK1
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SRC
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
17158356
|
NOTCH1
|
DTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14567914
15965470
|
AR
|
NOTCH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22347519
23145211
|
NOTCH1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17537801
|
PDIA3
|
ITGA6
|
â—¼ DISULFIDE_BOND
|
✅
|
|
2.0
|
0.8
|
intact
|
17170699
5219449
|
RELA
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11931769
5215238
|
HDAC1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19166851
6823802
|
RELA
|
HDAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23027620
|
APP
|
ADAM10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ADAM10
|
APP
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20676056
10097139
|
ADAM10
|
CDH1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18434311
15958533
|
PDIA3
|
ADAM10
|
â—¼ DISULFIDE_BOND
|
✅
|
|
2.0
|
0.8
|
intact
|
17170699
5219449
|
NCSTN
|
APH1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18201567
6174903
|
APH1A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP8
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP8
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10409650
10911620
|
RELA
|
MMP14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19303700
21627988
|
CSNK2A1
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5212888
10938077
|
RELA
|
NCF1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
12618429
5216185
|
AR
|
IL18
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15178407
20610535
|
HCK
|
CSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
CSF1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
CTNNB1
|
CDH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12640114
5216233
|
DNMT3A
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16887905
18974268
|
TBX2
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18829543
20624445
|
CTNND1
|
CDH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8660921
14610055
|
NOTCH3
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SRC
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731430
11940572
|
SRC
|
NGEF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15848799
11336673
|
ERBB2
|
GRAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9710588
|
KRAS
|
EGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
NRAS
|
EGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
IGF1R
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
7541045
|
PDIA3
|
ITGA3
|
â—¼ DISULFIDE_BOND
|
✅
|
|
2.0
|
0.8
|
intact
|
17170699
5219449
|
HCK
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12029088
5215418
|
CREB1
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10698518
|
MAPK11
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11532940
11335727
|
CREB1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10775268
|
PSMD4
|
PSMA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
TUBB2A
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TUBA1A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TUBA1B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
AR
|
INSR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
20417685
|
MME
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSEN2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSENEN
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAP2K2
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CSNK2A1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
CASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11967258
12191486
|
AR
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
16987234
|
CTNNB1
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12640114
5216233
|
CTNNB1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24291232
24482235
|
ERBB2
|
GRAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
KRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
NRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
SPTAN1
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
AR
|
ABCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15520169
20610535
|
AR
|
KRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8423674
24172884
|
AR
|
CD82
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11884637
20610535
|
AR
|
MME
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11162897
|
DLG1
|
MAP2K2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21615688
8182979
|
CD9
|
IGSF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11504738
|
PSENEN
|
NCSTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18201567
6174903
|
NCSTN
|
LAMP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
18201567
6174903
|
NCSTN
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10993067
|
SOX2
|
NTRK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22265740
|
CD63
|
TIMP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5218971
16917503
|
SNX9
|
SNX18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23085988
8408210
|
JAK2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
APP
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
CRK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ERBB2
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
GRB2
|
HCLS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
9670936
|
GRAP2
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
22973453
16273093
25241761
|
NDUFV3
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
NDUFA10
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
CDH1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
CD44
|
SNX33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CD44
|
SNX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CD81
|
CD151
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23091066
30024968
|
IGF1R
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17307140
30898150
|
BACE1
|
PDIA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15606899
20354142
|
CD9
|
CD151
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26686862
23091066
|
CDH2
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
NDUFA13
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
GRB2
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
CD81
|
PTGFRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
CTNNB1
|
CTNND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
GRB2
|
SNX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
31980649
21706016
|
INSR
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12456798
8912646
|
GRAP2
|
SNX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AXIN2
|
CTNNB1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
11940574
|
CSNK2A1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
LCK
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
BECN1
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28205554
23703612
28628118
28351972
|
CRK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23397142
10962563
12615911
|
STX4
|
RAB5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
11884531
|
PECAM1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
AR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
PTPN11
|
ERBB2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
32024694
|
NCSTN
|
PSEN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
CALM3
|
SPTAN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
KIF5A
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
NDUFA10
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
NDUFB2
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
NDUFS2
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
NDUFA13
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
CALM3
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
DTX1
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
SRC
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
16713569
11964172
9016807
12624098
|
SNX33
|
SNX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23085988
20964629
19487689
|
CRK
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8879209
9837978
|
PLCG1
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
6730306
1396585
|
SRC
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
1689310
7510703
16713569
7682059
8657103
8885868
|
ERBB2
|
GRB2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
14967450
|
INSR
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
IGF1R
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
CSNK2A1
|
SIRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
HDAC1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
ABL1
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22973453
16273093
19275932
|
ABL1
|
HCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9407116
10849448
|
CD44
|
CD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9117348
26686862
|
ITK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10636929
8985255
|
NTRK3
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10092678
7657612
|
FYN
|
PTPRF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12496362
31413325
|
CD82
|
CD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15492270
26686862
|
PACSIN1
|
PACSIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HuRI
|
32296183
|
NDUFA6
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CDH2
|
CTNND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
INSR
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
GRB2
|
DOCK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
31980649
21988832
21706016
33961781
|
ITK
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10636929
16713569
8810341
|
ITGB1
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CASP8
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CD151
|
ITGA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
FYN
|
CTNNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
12640114
|
SH3GL1
|
SH3GL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CD81
|
CD9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CRK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CD9
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
NDUFA8
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
NDUFS1
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PACSIN2
|
PACSIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
PDGFRB
|
PLCG1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
7535778
|
ABL1
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10708759
1383690
17474147
|
FYN
|
CD44
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9573028
16189514
16713569
|
LCK
|
CD44
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9573028
16189514
8576267
|
IGSF8
|
CD81
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
32900848
11673522
|
JAK2
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
10551884
|
CASP8
|
TRAF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
23142077
22179575
17047155
28972304
12887920
16227629
21282461
11340079
30054040
|
CD63
|
CD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12175627
8630057
11204565
|
APP
|
BACE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
PACSIN1
|
PACSIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CTNNB1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CD9
|
PTGFRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CTNNB1
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
ERN1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ABL1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
PDGFRB
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CDH1
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CD44
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21701559
11084024
9519902
|
CD44
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11606076
28628118
12093135
17092940
28205554
|
DLG1
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25241761
9341123
|
ITK
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12163161
10586033
|
SRC
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
31980649
19711372
9169421
33961781
16966330
|
ERN1
|
TRAF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25241761
16713569
10650002
12843613
25797626
25225294
11278723
|
CTNNB1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
5216126
12588987
|
IGSF8
|
CD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
11504738
26686862
33961781
26186194
30833792
|
CTNNB1
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
CDH2
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
NDUFA13
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
NDUFA8
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
CASK
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
NCK1
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
HDAC1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
APP
|
NCSTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
ERBB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
SRC
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11494128
17474147
12522270
11781820
17318191
|
CRKL
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16443220
22286129
7493940
14604282
8978305
9820532
18835194
9710592
33961781
8524328
19823681
7926767
16955467
24412932
|
ABL1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23950177
16713569
17474147
14725908
9407116
9516488
8194526
19380743
19823681
7926767
16955467
|
YES1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16787943
11847100
16076903
|
JAK2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7500025
17474147
8536716
8950973
|
FYN
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499280
9344857
|
CASP1
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10069390
|
CASP8
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10069390
|
PDGFRB
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
PTPN11
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
8119896
6730513
|
CDH1
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
16424155
16461340
17617594
|
PDGFRB
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10508235
9546424
9739761
|
ARHGAP32
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12446789
23331499
|
SNX9
|
SNX33
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
007278
7213590
19487689
|
CD81
|
CD9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
8630057
26686862
20124223
9804823
23091066
|
SRC
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10592173
11723131
11259684
|
LCK
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7682059
17570479
1500851
|
EGF
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8940074
1672440
10473558
|
PLCG1
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22973453
16273093
1676673
1683701
|
SRC
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15879121
20807769
11600407
|
INSR
|
PLCG1
|
â—¼ COLOCALIZATION
|
|
|
3.0
|
0.9
|
intact
|
200301131
14568990
6804839
|
EGF
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23613900
17081983
16525023
|
HCK
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9636140
16809022
23109003
|
CASP8
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8296476
18086677
706462200
|
FYN
|
TUBA1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7678277
11826099
|
NOTCH1
|
DTX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10933396
9881968
15356142
|
TSPAN33
|
ADAM10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
30463011
26686862
23091066
|
RELA
|
EGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15964798
21912613
23383347
|
RELA
|
IL18
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10227974
17399992
15963597
|
RELA
|
TIMP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14600595
17012236
|
RELA
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16713569
8798655
|
CASP1
|
IL18
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
1574116
9121587
8999548
|
AR
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18794357
20610535
|
SRC
|
CD63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
8312241
705574200
18211905
|
SRC
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22973453
11940572
17875712
19372587
21075308
29720121
7542762
7797556
19704002
|
SRC
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
30644389
26854235
9096340
|
SRC
|
PECAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12775720
10858437
|
EGF
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17496910
1334406
19531499
|
HCK
|
NGEF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15848799
25814554
11336673
|
CREB1
|
RARB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
|
AR
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
KLC1
|
KIF5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
3130248
1607388
3134048
|
AR
|
PHB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22179832
16964284
18487222
|
AR
|
MME
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
11162897
16949732
|
RB1CC1
|
ULK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19225151
18936157
|
CD63
|
TIMP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29523123
28030805
24635319
16917503
|
ABL1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
NDUFA10
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
NDUFB2
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
NDUFB2
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
NDUFA8
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
PECAM1
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
PLCG1
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
17474147
14978237
|
FAS
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
11717445
5214823
|
CASP8
|
FAS
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
5219431
17159907
|
FAS
|
CASP8
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
16498403
5218359
|
PSEN2
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
ITGA6
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CDH2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
PSMD14
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
CTNNA1
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
PSMA8
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
PSMA8
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
GRB2
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
16273093
5218056
|
CTNNB1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
36950384
|
NDUFA10
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CASP8
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
CDH1
|
CTNND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
SRC
|
CTNND1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
11382764
|
ERBB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
INSR
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
14568990
9593725
11796522
22974441
|
TUBA1A
|
TUBA1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
KIF5A
|
KLC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
FYN
|
YES1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
PSMA8
|
PSMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
GRB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
NDUFS5
|
UQCRH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
NDUFA13
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
ERBB2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
PLCG1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16713569
7629168
7516467
9020117
21706016
10940929
16038803
9281317
|
TUBA1B
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
PSENEN
|
PSEN1
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.96
|
0.96
|
Signor
|
12522139
|
FYN
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
NCK1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11494134
17474147
10967110
12379115
10372803
7926767
|
ABL1
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
9747873
11380621
15696159
8875975
9480911
21602891
18835194
18619508
12384576
8194526
11956190
19380743
24412932
9642287
17474147
8978305
12097319
17515907
33961781
12198159
7926767
|
ERBB2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9710588
11173924
21278786
16713569
9756944
24189400
31980649
22973453
24658140
30898150
16273093
17875712
16729043
11606575
8665853
|
CRK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8810325
10962563
8662907
19380743
10970810
|
AXIN2
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
APP
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
CDH1
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
PDGFRB
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ABL1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
MMP14
|
TIMP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
KLC1
|
KIF5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
10491391
33961781
9624122
22939629
26344197
|
PSEN1
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
APH1A
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NDUFA6
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NDUFS5
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
APH1A
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
NDUFA10
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
APBB1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
APH1A
|
NCSTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
NDUFA8
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
TUBA1A
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
NCSTN
|
PSENEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
NDUFA10
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
NDUFA10
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
NDUFA6
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
PSMA7
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
NCSTN
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
NDUFA13
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
NDUFA10
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PECAM1
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
NDUFA8
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ATG14
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NDUFA13
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CTNNA1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NDUFA13
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NDUFA13
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA7
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NDUFA10
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
NDUFA6
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
NDUFA6
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC1
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC1
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC1
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC1
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFA6
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD4
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ABL1
|
CRK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
ABL1
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
HCK
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
18775435
9407116
12522270
16787943
28087699
11847100
26473374
16912036
16076903
20841568
24708674
10849448
|
FYN
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12522270
16787943
17570479
16912036
16076903
17474147
11847100
|
SRC
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
19901323
10964922
16497976
20841568
16787943
17570479
17318191
11847100
10500097
12522270
18691976
11494128
11781820
16076903
20168609
12748290
16464493
12445832
19369195
17474147
|
LCK
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16076903
16787943
17570479
11847100
|
ABL1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
100.0
|
1.0
|
Omnipath
|
8978305
9747873
9480991
19426560
17081983
23124138
16522685
16713569
20841568
18768933
8875975
25860930
21779437
19534553
16187300
17515907
21602891
16267043
20068231
10592173
17570479
8194526
7926767
11080615
25381819
12198159
9642287
15696159
18619508
18835194
11956190
22848689
11314030
9480911
19001122
19402756
20697350
12384576
24412932
7542925
11380621
12799422
19380743
12955086
17474147
17016520
|
ABL1
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16705159
15923602
15793561
25821558
9111318
15143187
16705160
11593427
20841568
|
ABL1
|
HCLS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18305217
20841568
|
ABL1
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7615549
15817476
11774284
16254239
15107421
12408869
15572663
11695992
15592455
16094384
10823820
20841568
16713569
9603926
7537852
|
ABL1
|
NCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10372803
23331499
22327338
11494134
10967110
12379115
17474147
20841568
7926767
|
ABL1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
8978305
22581121
20841568
10837221
18768933
7493940
9710592
16955467
8524328
23331499
21199784
18794134
10592173
21051857
7926767
16443220
18835194
24165979
26500649
18809728
15459660
26192618
24412932
9053848
22286129
8083188
14604282
21435002
9820532
19823681
|
ABL1
|
SORBS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16831423
20841568
|
ABL1
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11279131
20841568
|
ABL1
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
8692915
8696915
14699166
12468540
10574931
7512963
16497976
20841568
14757045
8114715
10488096
|
ABL1
|
PDGFRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
14993293
19275932
20841568
|
ABL1
|
PSMA7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
16678104
25620702
20841568
|
ABL1
|
LASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15465019
17570479
15138294
20841568
|
ABL1
|
GRAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
23399893
8647802
7926767
|
ABL1
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11891774
20841568
|
ABL1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
11726515
16713569
20841568
8596638
16955467
10592173
8647802
8194526
7926767
14725908
23950177
8112292
9407116
23181695
19380743
17474147
9516488
19823681
|
ABL1
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
10708759
19290927
12652307
1383690
16525023
8657103
20841568
17474147
|
ABL1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16099633
25164010
17618275
24465953
20841568
17318191
20840866
|
ABL1
|
PSTPIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11163214
20841568
|
ABL1
|
APBB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20110615
15031292
18922798
26255939
11279131
22506131
20841568
|
CTNNB1
|
CD44
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18483247
12782598
17724465
10027409
|
CSNK2A2
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
19651622
19415658
17081983
20166139
18767875
11602581
20068231
18452278
17570479
17287340
19413330
18669648
|
CSNK2A2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12700239
19141652
12432063
|
CSNK2A2
|
CSNK2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
26186194
27705803
25519132
19011756
26496610
25852190
23455922
|
GRB2
|
GRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
GRB2
|
GRAP
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
PLCG1
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
NCK1
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
GRB2
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
FYN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
KRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
ITK
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11406363
12186560
15661896
25137453
|
LCK
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10652356
11062502
12731048
12740575
15536084
17544292
19290918
20814939
21127503
22513334
23620508
8478617
8986721
9438848
9738502
9751747
|
NRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
PTPN11
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10358138
11447289
11572860
12138178
12707331
15240681
15699106
15713798
19833085
9751747
|
GRB2
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
GRB2
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
GRB2
|
ITGB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
GRB2
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
PDGFRB
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7935391
16713569
7486683
|
ERBB2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
31980649
9756944
21278786
16273093
24189400
11173924
9710588
24658140
11606575
14967450
17875712
16713569
16729043
|
EGF
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17081983
19531499
17673906
10973965
|
JAK2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8536716
8950973
7500025
17474147
19273609
|
PTPN11
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
8702859
9361008
16371368
21706016
8041791
11085989
8978300
11432792
15882975
9362449
10212213
11684012
7523381
10592173
16189514
10747947
10973965
9632781
8959326
11602579
12577067
9254654
10080542
15010462
31585087
12531430
8995399
19380743
7522233
9804835
7534299
9824671
9660791
|
SRC
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12624098
11964172
9016807
16713569
26103942
20554525
|
GRB2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9281317
15953601
7629168
9020117
16713569
10940929
|
NDUFV3
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA13
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA13
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA10
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NOTCH1
|
PSEN1
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10879540
10206645
12209127
9620803
19151708
|
PSENEN
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12522139
12198112
15322109
16189514
21115843
12639958
|
NCSTN
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
12603837
23331499
21071413
14572442
12471034
10993067
18201567
18988627
12032140
|
APH1A
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12522139
12471034
16189514
12297508
|
PSEN1
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11518718
|
PSEN1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10593990
10077672
16713569
10206645
12374741
|
PSEN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
17145710
11168528
16126725
11226248
2195779
11161700
12070348
9738936
10037471
18070361
9632714
10092585
9223106
12297048
16306047
10341227
9852041
|
PSEN1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10635315
11226248
16126725
11953314
|
PTPN11
|
PTPN6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
42.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
17371980
19833085
20007250
20038811
20363967
20435894
21469115
22437870
22483603
22513334
22683124
22952938
22955274
23732914
25355530
26667266
26755705
26885856
27474009
27806234
28893624
8976179
8986721
9751747
9765283
|
PTPN11
|
PTPN6
|
â—¼ SHARES_COMPLEX
|
|
|
42.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
17371980
19833085
20007250
20038811
20363967
20435894
21469115
22437870
22483603
22513334
22683124
22952938
22955274
23732914
25355530
26667266
26755705
26885856
27474009
27806234
28893624
8976179
8986721
9751747
9765283
|
FYN
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
LCK
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
PDGFRB
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
8622870
19690332
8041791
18083107
8538796
23331499
19534553
11684012
7530043
16189514
12721296
12522270
8959326
17287340
16094384
7688466
8226787
8119896
12531430
11266449
12681492
12614164
8183548
23397142
7691811
|
FYN
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10212213
11157475
16713569
|
INSR
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8135823
9832615
7493946
9593725
|
JAK2
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8912646
23331499
21071413
7559603
8995399
9794795
|
PTPN11
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9756944
16273093
16729043
32024694
|
PTPN11
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
23397142
10082579
8986614
10655584
14665621
|
PTPN11
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
18950707
23109003
16371368
17722974
22315502
16107703
9660791
8080844
9632795
15790353
|
PTPN11
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
18757826
18482983
10698938
17974954
14687660
24632723
20308328
|
PTPN11
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
28065597
23331499
11779860
7642582
10082579
8895367
|
RELA
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20617556
15152190
24064732
|
SIRT1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19408108
25217963
15152190
21081649
|
CXCL3
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
129648828702798
8702798
16189514
12964882
|
CTNNB1
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24447505
15473860
11809809
22615875
11809808
12711682
11940574
|
HDAC1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
CTNNB1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10966653
19751508
7542250
8666229
17143292
11955436
11967263
23343194
22270359
9554852
22699938
16039586
16940750
9566905
19619488
15766563
12051714
|
INSR
|
CALM3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
17389395
19901323
18578522
12153558
18707149
20068231
16497976
17287340
15592455
2843348
7925415
3415247
8639568
17016520
18669648
|
SRC
|
JUP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8081883
14517306
23911551
|
FYN
|
JUP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14517306
|
CRK
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRK
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
FYN
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
11062502
12218089
12731048
15536084
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
CRK
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRKL
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9092574
9461587
11553620
|
CRKL
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8978305
7493940
9710592
10592173
11463817
|
ITGB5
|
CRK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
BECN1
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG14
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
19270693
19050071
25594178
19223761
18843052
27513923
26496610
23954414
23332761
22081109
20562859
26108642
25891078
24034250
23112296
32296183
24980960
19270696
21062745
20711182
25490155
|
CXCL3
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
22633458
|
CRK
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
PXN
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12198159
27686861
12799422
10329689
10592173
10085298
16713569
7525621
8662907
7537852
|
PDGFRB
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
19426560
10733900
16713569
27686861
|
ARHGAP32
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
12446789
12454018
12819203
|
IGF1R
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
12198159
9642287
9480991
9480911
20068231
11956190
8194526
8875975
15522217
17016520
|
CRK
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12198159
27686861
12799422
10329689
10592173
10085298
16713569
7525621
8662907
7537852
|
CRK
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
35044719
19380743
25814554
11418612
|
PDGFRB
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
17081983
7486683
2472219
16126727
15592455
7535778
16713569
23331499
1689310
11896612
15641795
16153436
16038803
23063561
1708307
7682059
15144186
12601080
1396585
8885868
8657103
8443409
23397142
15212693
|
PDGFRB
|
NCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1333047
23331499
10026169
9362449
16189514
16636066
|
PDGFRB
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
1696179
7685273
7687537
16713569
1661130
9425276
|
PDGFRB
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15489898
18315570
16189514
9010229
2173144
|
ITGB1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
LCK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
LCK
|
ITK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
PTPN6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
LCK
|
PECAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26956486
9624175
12207897
|
LCK
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
23071622
8692915
16231973
23109003
14699166
19167335
12459785
12468540
11294838
10574931
7512963
16497976
16189514
14757045
8114715
10488096
|
LCK
|
ITK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
21747996
28516764
19132916
23109003
20305788
23982207
15771581
19690332
28644030
15144186
9312162
12842872
17192257
23946894
|
LCK
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14583609
23331499
16713569
|
LCK
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11526404
15032589
14583609
23109003
8397196
10488096
|
PLCG1
|
GRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
PLCG1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10072481
10781611
10811803
10925299
11169415
11476890
11532940
11994416
12040186
1281218
12845332
14585353
14764585
15214048
16488589
16919435
1712101
17397400
17496910
17517963
19568798
19909365
23523669
24584707
2536067
25456276
25572304
25960930
26552706
27216177
7682895
7890616
8226994
8649391
9535722
9846483
|
PLCG1
|
SRC
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10072481
10781611
10811803
10925299
11169415
11476890
11532940
11994416
12040186
1281218
12845332
14585353
14764585
15214048
16488589
16919435
1712101
17397400
17496910
17517963
19568798
19909365
23523669
24584707
2536067
25456276
25572304
25960930
26552706
27216177
7682895
7890616
8226994
8649391
9535722
9846483
|
PLCG1
|
GRAP
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10072481
10086337
10209041
10567412
10781611
10811803
10925299
10982827
11169415
11447289
11532940
11777939
11994416
12175651
12640133
1281218
12845332
14764585
15214048
15567848
15574420
16102570
16329184
16582911
16887996
1712101
17397400
17496910
17673906
19449109
19494291
19909365
23523669
23620508
24584707
25137453
2536067
25456276
25960930
26552706
7523143
7682895
7890616
8226994
8551221
8649391
8976179
8995379
9489702
9535722
9846483
|
ITK
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11406363
12186560
15661896
25137453
|
NCK1
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
ERBB2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
16273093
1676673
1683701
|
NTRK3
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10235685
23331499
10092678
7657612
8344249
|
JAK2
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17474147
14978237
|
SRC
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
8388373
16497976
16126727
16713569
17389395
1689310
20068231
17570479
16153436
16038803
1708307
7682059
7510703
18594017
12601080
8885868
8657103
17016520
|
GRAP
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8995379
23331499
9281317
|
FYN
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8395016
10586033
7682059
16713569
|
HCK
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
17081983
16497976
15592455
16126727
17389395
1689310
20068231
16153436
16038803
10586033
1708307
7682059
15144186
12601080
18707149
8885868
8657103
17016520
|
ITK
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
24412752
15975899
22847294
20237289
15623534
19690332
12163161
23933134
30131370
15184383
16126727
12730118
31196981
17389395
23331499
19534553
20519342
16081816
15215251
17372230
17420479
27221712
17148460
21760611
12952950
25916191
19427038
27941787
10586033
34429382
23109003
11564877
12029091
12941616
19412549
14568990
28644030
11709089
8657103
15951569
22649724
|
FYN
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7617039
10804218
16713569
23128389
|
SRC
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
9636140
28214467
15572663
15592455
16713569
14665621
25795725
7537852
7615549
25405379
11774284
26700725
25182764
15107421
7534286
2472406
12408869
11695992
17570479
10823820
7525621
20103658
16254239
15817476
23109003
27447856
28626446
16094384
18363833
19543320
24364863
28376152
19138410
25323586
27941878
23457577
10085298
22638989
27669437
15212693
|
INSR
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
8692915
14699166
12468540
7512963
17570479
16497976
18377662
14757045
8114715
|
SRC
|
PTPN6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
8692915
17675340
14551136
25535246
14699166
12468540
10574931
16649996
8647855
7512963
9261115
34010642
14757045
12468645
8114715
15212693
10488096
21900501
|
PTPN6
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
8943354
21071413
10772872
15983048
18988627
|
PTPN6
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21780115
15032589
11526404
23109003
9065461
22880054
10488096
|
PTPN6
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18086677
|
PTPN6
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10835420
|
FYN
|
ARHGAP32
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
12788081
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
NCK1
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
FYN
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
7515100
1334406
16713569
1652056
|
FYN
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
26477567
11777936
17194753
|
FYN
|
ARHGAP32
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12857875
12788081
|
FYN
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
14761954
28598420
18056410
8633244
|
FYN
|
ARHGAP33
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16777849
|
FYN
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
20026641
22264731
24511551
25241761
22340496
12640114
25803041
26509276
|
FYN
|
PTPRF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12496362
18854310
|
TRAF2
|
ERN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11274345
15592525
17462996
18641653
19392652
21133840
21232017
23850759
24378531
|
TRAF2
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15024054
20696707
19278658
10837247
19416807
21235526
|
TRAF2
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
TRAF2
|
ERN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11274345
15592525
17462996
18641653
19392652
21133840
21232017
23850759
24378531
|
TRAF2
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
TRAF2
|
SDHC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11274345
12847084
15592525
17462996
18641653
19392652
19509052
21133840
21232017
23430059
23850759
24378531
26587781
|
TRAF2
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
15592525
17462996
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
|
TRAF2
|
FAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
RELA
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15041463
19392652
21573233
15723831
9733516
|
ERN1
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
25797626
25241761
18519638
11278723
12843613
25225294
16713569
10650002
|
TRAF2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17145710
12887920
20203691
16227629
21741934
17047155
22421964
30054040
11340079
|
TRAF2
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
SRC
|
JAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11476890
12094222
16919435
17496910
17517963
25572304
26552706
27216177
|
JAK2
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
DTX1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
11153911
20208568
23331499
21071413
11226752
11564735
22162134
18988627
|
ADAM10
|
NOTCH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
18676862
19601831
19704010
19726682
22006996
|
ADAM10
|
NOTCH1
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9244301
12354787
17401372
10882063
19726682
|
NOTCH1
|
PSEN2
|
â—¼ CLEAVAGE
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10879540
10206645
12209127
9620803
19151708
|
PSEN2
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11518718
|
ADAM10
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19726682
28624438
19704010
19601831
22399336
|
HDAC1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20580679
19182791
21685935
21184735
24424621
18794357
|
CSNK2A1
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
19651622
19415658
17081983
20166139
18767875
11602581
20068231
18452278
17287340
19413330
22113938
18669648
|
HDAC1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564889
11931769
16483679
30670829
16325585
16713569
17183360
21983014
|
HDAC1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11994312
16713569
15640443
12612053
10428808
|
ADAM10
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
32814053
30538620
12535668
|
ADAM10
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12651094
23331499
19726682
19704010
19601831
|
NDUFB2
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFA13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA13
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFA6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA6
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA6
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFA8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFA8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFA8
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA8
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12601012
12667446
15186778
15526035
15807660
16200211
16218961
16246152
17344420
18485875
19131594
20025615
20816094
23850759
|
NDUFB2
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFB2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFB2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB2
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12601012
12667446
15186778
15526035
15807660
16200211
16218961
16246152
17344420
18485875
19131594
20025615
20816094
23850759
|
NDUFB2
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFS2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS2
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NCSTN
|
APH1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
15189355
21071413
14572442
12471034
12857757
18201567
12297508
|
APH1A
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12471034
16189514
12297508
|
APH1A
|
PSENEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12522139
15322109
12740439
16189514
|
SRC
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
27432652
16619028
19470771
27109099
27195913
19383910
30501030
24100030
22074016
|
CASP8
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|
CASP8
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17170703
9535906
16713569
|
CREB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
CREB1
|
RELA
|
â—¼ PROTEIN_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
CREB1
|
RELA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
21.0
|
1.0
|
ACSN
|
11579131
12417340
15079071
15187187
15279786
15337521
15536066
16007092
16713974
17303408
17550372
17565603
17660363
18590585
19171876
19879327
20144767
23430059
7575488
8383323
9743347
|
RELA
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24466341
16619263
14576180
15517885
14715080
|
RELA
|
CSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10919279
11949945
21825016
21895511
21106671
18566389
|
CSNK2A1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
34049972
15016307
10938077
27630163
|
CASP1
|
IL18
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22270365
17039247
15326478
9121587
9334240
|
NCF1
|
MAPK11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
16778989
25877926
14530365
27558335
|
CDH1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CDH1
|
CDH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
CDH1
|
CDH2
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
11884419
16424155
16461340
17307799
17617594
|
CTNND1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
7542250
17261850
22752307
9535896
7651399
12707304
23180380
24424122
12640114
11226248
29207493
10225956
12427869
21670201
22850631
20371349
20940130
25468996
10409703
14610055
7876318
22715382
10629228
19711372
8660921
10931041
|
CSNK2A1
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
10837139
11348595
20976471
17928543
20558317
10671551
17374729
21285348
11972058
21506126
11689703
10747897
10671552
16707567
|
CDH1
|
CTNNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17145710
7542250
19016843
25468996
9326449
16212417
11960376
11801604
8227214
10381631
16219695
9700170
24336504
22750944
9233779
11226248
|
CDH1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17496910
19029934
22370635
16099633
23343194
19734908
10744074
16039586
22203675
19171760
22007144
19619488
17143292
|
CDH1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
91.0
|
1.0
|
Omnipath
|
17145710
7542250
11348595
9512503
10652321
19016843
16909210
9233779
17220478
16219695
27177845
25344754
11245482
22752307
16983094
16212417
16574648
18593713
9535896
9819408
12830000
10772923
11801604
23180380
8227214
16546130
10085258
22056988
9700170
12640114
24424122
10381631
17087658
24798214
11226248
12875984
9405455
11712088
12061792
17909039
22158051
11960376
14706341
11254878
15023525
12169098
21255999
16125672
22850631
16126725
11113628
25468996
9326449
17524503
17057644
7876318
11401320
22715382
7954478
18593907
21152425
22375065
|
AR
|
CDH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18535113
17297473
20610535
|
SRC
|
CDH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16371504
15782139
9592087
16492141
9278444
28163245
10502299
|
CDH2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
18948590
20398329
21506126
20028971
12040186
12604612
21303971
20214616
17098867
11882383
22094462
8120095
21357690
17679699
17680028
12151522
17057644
21255999
18218901
|
ITGA3
|
SRC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
56.0
|
1.0
|
ACSN
|
10671552
11133108
11348595
11476890
11955436
11967263
12051714
12426320
14557817
15001769
15279786
15548370
16039586
16099633
16371504
16474430
16919435
17143292
17303408
17496910
17517963
17660363
17928543
17934056
17936032
18037882
18590585
19010789
19029934
19109155
19171760
19619488
19734908
19920116
20519943
20644162
20705860
21278795
21666923
21900405
22007144
22174153
22203675
22370635
22674073
22703233
23343194
24023259
25572304
25730849
26552706
27216177
7542250
7575488
7594497
8666229
|
AR
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19305643
10454563
18687691
17108144
17079466
|
ERBB2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16769082
19617202
11940572
12753909
21075308
7542762
|
ARHGAP32
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
12454018
|
EGF
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23349873
19481075
15845350
22927910
27462789
|
SRC
|
LASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
32872485
24913448
32075106
19718473
15138294
25622104
|
SRC
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21780115
15032589
11526404
23109003
22880054
10488096
|
SRC
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
28144231
15062576
20570899
25133482
21318111
11032808
25950519
21512132
17525795
12933816
20383201
24728074
24948875
24868554
25547388
19117998
21956655
17045208
15027889
24859991
15466214
26829214
21886458
|
SRC
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17389395
11382764
19138410
20068231
18707149
17194753
23457577
26477567
14996911
17016520
18669648
|
SRC
|
SPTAN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12446661
11971983
|
SRC
|
SH3GL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23255596
16054026
|
SRC
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17389395
15212693
18691976
7559478
7493944
7537849
20068231
23472139
8550552
17016520
8940173
9480911
|
SRC
|
ARHGEF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18653540
|
SRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
22605996
16492141
27177845
23824743
25423132
25850673
24816560
27203386
11836526
22515442
26918136
10593980
15782139
9592087
22056988
12571228
17087658
20840866
23640056
21195420
25164010
26453937
9278444
16831887
23476652
12123611
11279024
14517306
21903109
22200182
20026641
22264731
25041845
12408824
22247700
|
ITK
|
GRAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11406363
12186560
15661896
25137453
|
AR
|
EGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18511414
8580999
7522959
15590903
14662770
18692155
17374439
18212060
20610535
|
EGF
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15748904
23331499
12093292
11279155
|
AR
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19318566
15033751
17202144
19250214
20610535
|
IGF1R
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17496910
22558232
12040186
19568798
14585353
|
HCK
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
21780115
11526404
15032589
23109003
12029088
22880054
10488096
|
CSNK1A1
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17209043
9931297
|
PTPRF
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23331499
7852302
10734133
15588985
11158333
10592173
1321126
8732688
19910497
8995282
1303753
|
BACE1
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
30538620
22801501
10677483
20418918
12901838
10531052
10931940
32814053
28923680
28869759
19251705
|
CSNK2A1
|
CTNNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20858269
31432583
20093040
32256776
19941816
|
CSNK2A1
|
MME
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22767595
20957047
|
CSNK2A1
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8972483
9558331
20068231
9990034
|
CSNK2A1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12700239
12432063
|
CSNK2A1
|
HCLS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10806407
|
AR
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18535113
18673534
20610535
11916967
|
ERBB2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17496910
7702605
7999105
22558232
14517306
11245482
11950845
12040186
19568798
23576562
14585353
23640056
|
CSNK1A1L
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
11955436
17172446
12000790
19293931
11818547
12114015
|
CSNK1A1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
64.0
|
1.0
|
Omnipath
|
9312064
29495399
14966280
23531534
21764279
26227550
29793495
28220106
20561505
26862734
19293931
19623618
27558955
28430641
11818547
25546293
16199882
24648413
28337019
27672271
11955436
9482734
25915038
20419129
23778311
19244247
25500543
27768599
27488834
28183999
17208333
24594309
24038789
23076981
24904820
23690993
23744610
12000790
23687614
12114015
10488109
26604501
19711366
20699366
25517963
26189775
10023673
22025562
|
AR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
21741601
16713569
12799378
12944908
10809237
23331499
15060161
21071413
21885566
18988627
16428447
11916967
12588987
11792709
10987273
14593076
15256534
22187462
|
PTPRF
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10187801
9245795
11245482
12095414
|
MAPK11
|
MAP2K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
ERBB2
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17496910
22558232
12040186
19568798
14585353
|
ERBB2
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17496910
16273093
1334406
16729043
|
SPTA1
|
SPTAN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22013193
19758564
24119662
19164740
|
CASP1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9535906
16713569
|
KRAS
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
PSEN2
|
NOTCH3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11518718
|
PIK3R2
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3R2
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
CASP1
|
PSEN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10069390
9219695
9990034
|