Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EGFR ERBIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23220880 22908275
EGFR CAVIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
PIK3R1 IGF1R â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6730400 7589433
RAI14 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP STT3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP VAMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 FZD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12095419 15473860
ABI2 SNAP23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TGFBR1 ITGA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8410211 22940691
BASP1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FLOT2 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
CTNND1 CDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8660921 14610055
IGF1R PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7541045
TNFAIP3 LAPTM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
CTSD SPRY4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARHGAP1 RHOC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NPRL2 ITFG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
NPRL2 KPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
ERBIN CTNNB1 â—¼   COLOCALIZATION 2.0 0.8 intact 5215447 12047349
PTK7 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23151663 21132015
NPRL3 KPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
NPRL3 ITFG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 29123071 28199306
TMX1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOD1 CTNND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SOD1 LAMP2 â—¼   COLOCALIZATION 2.0 0.8 intact 8141566 21252941
ABI1 PIK3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
HYOU1 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DSG2 NCSTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18942891 0060257
NCSTN LAMP1 â—¼   COLOCALIZATION 2.0 0.8 intact 18201567 6174903
GBA LAMP1 â—¼   COLOCALIZATION 2.0 0.8 intact 7555317 20148966
STX7 YKT6 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
IGF1R PIK3R1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
PIK3R1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16273093 5218056
NPRL2 WDR59 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 28199306 23723238 28199315
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ABI1 BAIAP2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
SEH1L WDR59 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SNAP29 VPS51 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EGFR IGF1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
NTRK3 MTOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SEC63 RPN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33957083
LAMP1 FZD7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PDIA4 EMC7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PVR LRBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ROCK2 ROCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LAMP1 RAB4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STX7 SCFD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
SNX3 STX7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22939629
STX7 VPS45 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26186194
WDR59 NPRL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25263562 28199306
SZT2 NPRL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28199306 28199315
LAMP1 FAM3C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LAMP1 FZD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LAMP1 ZFPL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 26344197
CDH2 CTNNA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CTNNB1 CTNND1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
STX12 STX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SEC13 WDR59 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25263562 28199306 33961781 26186194
SEC13 STX7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SEC13 WDR24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25263562 33961781 26186194 23723238
APBB2 GOPC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
APBB2 WDR41 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ITFG2 SZT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 28199306
KPTN SZT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 28199306
WDR59 SZT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28199306 28199315
NCKAP1 ABI1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 15048123 5216987
LAMP1 DSG2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
LAMP1 CNNM3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
LAMP1 TMX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
PLAA VCP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
NPRL3 WDR24 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
WDR24 NPRL2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23723238 28199315
NPRL2 SZT2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28199306 28199315
SNX3 VPS35 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24344282 33961781 22673115
WDR24 WDR59 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KPTN SZT2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
NDRG1 RAB4A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17786215 28776325
DEPDC5 ITFG2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ITFG2 SZT2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CDH2 CTNND1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EGFR ITSN2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
STX7 STX12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
STX7 STX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
STX7 YKT6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33422265 33961781 26186194 34079125
ABI1 ABI2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26496610
RPN2 STT3B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 22939629 33961781
KPTN ITFG2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17353931 28199306 33961781 26186194
CTNND1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SNAP29 STX7 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DEPDC5 MIOS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AIM2 PYCARD â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
DEPDC5 SZT2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PIK3R1 PIK3R2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ITFG2 KPTN â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATP6AP2 ATP6V1A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SNAP29 STX12 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
WDR24 SZT2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28199306 28199315
EGFR PIK3R2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MIOS NPRL2 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NPRL2 WDR59 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RPN1 RPN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32788342 33961781 34079125 22939629 26344197
RPN1 STT3A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 32788342 30021884
RPTOR RRAGB â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
STX12 VAMP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
STX12 YKT6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
STX7 VAMP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 34079125 26344197
NPRL2 NPRL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 28199306 33961781 23723238 27684187 19521502 28199315
WDR24 NPRL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28199306 25263562 23723238 28199315
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EGFR PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MIOS WDR59 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MIOS SEC13 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
APBB2 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24658140 16273093 25402006 31980649
EGFR MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20624308 24189400 21918175 24362532 10722725 23866081 26551075
MTOR RPTOR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16847060 26522726 12604610 19619545 26348909 33378666 20169205 24036451 18570873 24516643 19299511 34031390 22424946 22356909 25940091 12719976 22544753 23263282 12150926 12665511 18505677 17277771 17461779 22493283 19114562 18722121 21071439 18030348 19446321 12718876 12747827 24375676 22258093 16837165 21045808 16962653 18955708 17565979 12408816 15467718 23953116 27043084 23911927 17043309 31601708 21177249 21614075 21795849 16631613 20381137 21321085 23297343 23872070 16354680 19875983 25446900 29059166 24337580 16603397 16183647 34171383 15066126 24403073 25332233 17386266 19145465 25007995 16798736 26678875 15268862 20427287 30865892 16919458 25273559 15459249 18519641 18504440 12150925
TGFBR1 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9435577
WDR24 WDR59 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28199306 25263562 23723238 28199315
SCFD1 SEC22B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
STX5 YKT6 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
STX5 YKT6 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 11927603 33961781
CDH2 CTNNB1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MIOS WDR24 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CTNNB1 CDH2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 36950384
ATP6AP2 ATP6V1F â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CASK LIN7C â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
SCFD1 STX5 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 28514442 14565970 12506202 33961781 26186194
SNX3 VPS35 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
SEC13 SEC24B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ATP6V1B1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSPA5 HYOU1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
ATP6V1A ATP6V1F â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ATP6V1A ATP6V1B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
MIOS SEH1L â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
RPN2 STT3A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ABI1 NCKAP1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RPN1 STT3A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
RICTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24036451
MTOR RICTOR â—¼   COLOCALIZATION ✅ 0.97 0.97 mint 21045808 8088164
SLC3A2 SLC7A5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
SEC22B STX5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
RPN1 STT3B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 32788342 30021884 34079125 22939629 19167329 26344197
DEPDC5 NPRL3 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
NPRL2 NPRL3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPN2 STT3B â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
DDOST STT3A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPN1 STT3B â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
ABI2 NCKAP1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SCFD1 STX5 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
DEPDC5 NPRL2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DDOST STT3B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPN1 RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SEC13 SEH1L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17496910 31980649 23956138 19531499 16273093 24658140 11172806 1334406 25402006
EGFR SCAMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9658162
EGFR CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17145710 22558232 18950621 23481205 25402006 12040186 24797263 9535896 17389395 20068231 19568798 27316454 14585353 17496910 24189400 15657067 24658140 31980649 26067913 15951569 14996911 17016520
EGFR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17496910 26918608 7797556 25241761 19531499 16273093 8662998 14967450 16713569 21701776
MTOR RICTOR â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RICTOR â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
MET PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 15735664 7513258
IGF1R PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8603569 17496910 25241761 8697095 7642582 17570479 18595745 7589433
TGFBR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15657037 9435577
CTNNB1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10477752 25241761 16219695 11716761
TYRO3 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 10627473 18988627
PYCARD AIM2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 19104081 23702978 26885855 27048821 27066895 27984721
PYCARD AIM2 â—¼   PROTEIN_INTERACTION 6.0 1.0 ACSN 19104081 23702978 26885855 27048821 27066895 27984721
PYCARD AIM2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 19104081 23702978 26885855 27048821 27066895 27984721
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 ITGA5 â—¼   PROTEIN_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
IGF2R VPS51 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258
ADAM10 NOTCH1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 18676862 19601831 19704010 19726682 22006996
ADAM10 NOTCH1 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 9244301 12354787 17401372 10882063 19726682
ADAM10 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19726682 28624438 19704010 19601831 22399336
RIPK3 CFLAR â—¼   PHYSICAL_INTERACTION 45.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866
RIPK3 CFLAR â—¼   SHARES_COMPLEX 45.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866
RIPK3 CFLAR â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16498403 16940415 17462996 18641653 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 24366341 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866
SLC3A2 LGALS3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10426994 11907067 15536084 16713974 18250477 22703233 26653790 26794443 27048822
SLC3A2 LGALS3 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 10426994 11907067 15536084 16713974 18250477 22703233 26653790 26794443 27048822
CDH2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18948590 20398329 21506126 20028971 12040186 12604612 21303971 20214616 17098867 11882383 22094462 8120095 21357690 17679699 17680028 12151522 17057644 21255999 18218901
IGF1R CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
SEC22B SEC13 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22013193 10982397 23378591 20545907 18843296 10825291 20679433 11035026
SEC22B SEC24B â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22013193 10982397 23378591 20545907 18843296 10825291 20679433 11035026
ROCK2 RHOC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11283606 15699075 8816443 11294240 8617235
MET CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17496910 25163657 24511551 22558232 11929826 16909210 24342833 12040186 26654598 19568798 14585353 23083465
MET CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
MBP PLP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 2467009 6083474 16713569