Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAPK1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217079 15225643
MAPK1 BCL2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217079 15225643
BCL2 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313378
HMGN2 CBX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CDC7 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
CDKN1A UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7298683 19536131
HNRNPK CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16360036
TRIM28 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942393
DDX21 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRIM21 DDX41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21862588 23222971
KHDRBS1 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
GRB2 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX5 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
GRB2 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HNRNPA2B1 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6542847 18519039
DHX9 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SMARCD1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SMARCD2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HMGN2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HOXC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ABLIM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EEF1G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EEF1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
GRB2 SNRPD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPS11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RUVBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RBBP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPS25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL23A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 KHSRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RPL23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
IL2RB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10602027
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
SYNCRIP HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NOS3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RBMX HNRNPK â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
HNRNPK HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HRAS HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPD1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT5 SNRPD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KRT19 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
BLZF1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A SMARCD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A STX11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PARP1 MAPK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
FRS3 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15485655
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK3 GAB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217186 15356145
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
UBC NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
PTBP1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
NPM1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
HRAS SMARCB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EEF1A1 TAF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRIM28 TBL1XR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11013263
XRCC6 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HRAS KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLR1C MKRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MKRN3 ENKD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MKRN3 POLR1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TSEN15 LMO4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HSPA8 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26902588 25961502
SOCS3 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16568091 22547065
SOCS3 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10421843 10064597
ILF2 EEF1G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SOS1 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9544989 6547749
SHC1 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10704825 5212298
RASA1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8155326
IL2RG SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8643566
HRAS SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
JAK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9670964
PIK3R2 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
IL2RA JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
RASA1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221569 9219684
HRAS BLZF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL2RA IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RG IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RG PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10421845
IL2RA IL2RB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RB IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RA IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607058103 17032757
JAK3 IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IKZF3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20676092 22751139
UBC RHOA â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5217531 15710384
CDK4 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25733683 18719096
CDK4 CDC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
EEF1G PKN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
USP2 UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
HMGN2 RPL23A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EEF1G SNRPD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EEF1G EEF1D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HNRNPA1 KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20186123 7890613
HNRNPA3 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PIK3R2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 9651378
HSPA5 MIPOL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
HNRNPM HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPA3 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CHD3 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PIK3R2 IGHG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PTBP1 ZMYM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15975576 5217783
IL2RA JAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
SPG21 DTX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PRDM1 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24120360 17182561
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
KLHL38 KRT85 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
JAK1 SOCS3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10707961 10373548
HNRNPA1 HNRNPM â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
GATAD2B RBBP4 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
EEF1A1 EEF1G â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
SMARCB1 ACTL6A â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
DDX41 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DDX5 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26344197
DDX5 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 20676135
DHX9 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15723802 30585729
KDM1A CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19703393 21937684
TAF6 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14580349 23292512 22939629 26344197
TOP1 RBM25 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
CHD3 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 30585729
SHC1 SHC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IKZF3 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
MTA1 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12920132 24981860
SIN3B SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
CDK4 JAK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
IKZF3 CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
MBD2 MTA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
FRS3 STK16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
MRPL28 MRPL53 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
NPM1 RPL5 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
HDAC2 ZMYM2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
SHC3 GRB2 â—¼   RELOCALIZATION ✅ + 0.82 0.82 Signor 16829981
KDM1A ZMYM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18806873 33961781 34079125 12493763 16140033 16079794
TAF6 TAF9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23292512 7597030
SHC1 IL2RG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 8643566
LCK KHDRBS1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 7208262 16107303
MTA2 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11602581 12920132 24981860
HDAC4 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17011572 10220385 17210713
RBBP4 MTA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
CHD4 MBD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28977666 24981860 32744500
RBBP4 SIN3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
ILF2 SNRPD2 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CHD3 TRIM28 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
GATAD2A GATAD2B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GAB2 SHC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HSPD1 SNRPD2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EEF1A1 RPL23 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EEF1A1 EEF1D â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
RASA1 GRB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 12441060 16713569
GRB2 PPIA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
TOP1 NONO â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15848144 24981860
ZGPAT RBBP7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24116224 19644445
EEF1A1 RPS25 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6613464 18451879
HDAC2 FOXP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19276356 25609649
KHDRBS1 HNRNPA1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24514149
CHD4 CHD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28977666 32744500 24981860 22939629 9885572
KDM1A ZMYM2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HNRNPK HNRNPM â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
FOXP3 IL2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
IL2RB GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 10602027
PARP1 HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 16204234 20596014
DOK2 LCK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10799545 16189514 25814554 15831486
MTA1 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6613464 18451879
BLK SOCS3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
HNRNPK KHDRBS1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
TRIM21 UBC â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MBD2 RBBP7 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CBX3 XRCC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21888893
KAT5 FOXP3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17360565 19996091
IL2RA IL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17032757 16477002 1993646
HDAC4 RBBP4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31040226 10220385
HSPA9 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
GOLGA6A KLHL38 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
SOCS3 YES1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
KLHL38 MKRN3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
GOLGA6A MKRN3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
EEF1A1 RPL23A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
DHX9 ILF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 22939629 23986595
MBD2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194 11297506
RBBP7 SIN3B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194
MTA1 CHD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12431981 24981860 17922035 28977666 9885572 26344197
ZGPAT MTA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24116224 19644445
HNRNPK RBMX â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ACTG1 RUVBL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD2B MTA1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IL2RB JAK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PSMA1 UBC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD2A MTA2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BCAS2 SNRPB â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GATAD2A MTA1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
KHDRBS1 RASA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HNRNPA1 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BCAS2 LMO4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MKRN3 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HDAC2 SIN3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPL PTBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
JAK1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527382 8536716
PARP1 HMGB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29721183 28190768 34079125
MTA2 KDM1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21670149 19703393 21937684
KDM1A MTA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21670149 26028330 19703393
RBBP7 MTA2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
GATAD2B MTA2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
SIN3A MBD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10950960 24981860
IL2RG IL2RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11886175 10903799 8006584 20816854
MTA2 MTA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24981860 21670149 12920132 34026424 26344197
MTA2 CHD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19703393 28977666 10444591 24981860 22939629 11297506 26344197
SMARCD1 SMARCD2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
GATAD2B HDAC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HNRNPA1 HNRNPL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
GRB2 KHDRBS1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ACTL6A SMARCD2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CBX3 TRIM28 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CHD3 GATAD2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
GATAD2B MBD2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
FBL RPS11 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PRPF19 RBM25 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EXOC8 KRT19 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRT19 KRT85 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CHD4 GATAD2B â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GEM MKRN3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CBX3 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 28977666 21888893
CHD3 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 28977666 27705803 33961781 26186194 22939629
CHD4 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 9790534 25247294 33961781 26186194 28977666
TAF5 TAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14580349 23292512 11406595 26344197
GAB2 SHC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12135708 14982882 10704825 11782427
SHC1 IL2RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 8294403 10602027
PRDM1 HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10713181 12626569 22733990 19124609 22555612
HDAC2 SIN3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15935060 26949739 21258344 24981860 16464847
MTA1 CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 26028330 32744500 24981860 21670149 24440720 12920132 9885572 26344197
CHD4 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9790534 28977666 27705803 32744500 33961781 24981860 21670149 22939629 9885572 26344197
MBD2 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 24981860 11297506 10444591
CHD3 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 27705803 33961781 24981860 22939629 9885572
MBD2 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 10471499 33961781 24981860 25753662 11297506
GATAD2B RBBP7 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MTA1 MTA2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
GATAD2A HDAC2 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
BYSL STX11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
RPS2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EEF1A1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ING5 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A RBBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT5 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17671089 20351180 16601686
MBD2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22241836 22371483 19738071
SHC3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16729043 12242309 16829981
JAK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8536716 11527382
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
GRB2 IKZF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32296183 25416956 27107012
KDM1A HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 32882276 19703393 9804427 12032298 20164337 28667074 26949739 34031383 21258344 26344197 34050636 21670149 24981860 11102443 12493763 16079794 21937684
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 CHD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20693977 26565020
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
MTA2 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 19703393 22939629 20714342 14645126 10444591 27705803 28179136 33961781 24981860 26186194 12920132 11297506
SIN3A RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9651585 17255935 27705803 33961781 24981860 26186194 12453419 15451426 11784859
XRCC6 VBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RASA1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SHC1 NUDT21 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NUDT21 EEF1G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LCK DOK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 10799545 16189514
LCK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11572860
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
JAK1 IL2RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7973658 9774657 7973659 8700888 8041779 9553136 20816854 12133952
MTA2 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 31980649 19703393 22939629 30737378 20714342 26949739 10444591 21258344 24981860 12493763 19686092 11102443 12920132 18451879 11297506 26344197
HDAC2 CHD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12198550 23752268 22939629 9804427 30737378 28977666 26949739 24981860 17827154 12493763 9885572
HDAC2 ZMYM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 26949739 21258344 33961781 12493763 18806873
HDAC2 MBD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 26949739 10471499 10444591 16410616 21258344 24981860 11297506 25753662 12183469 26344197
HDAC2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 9790534 9804427 11003653 22939629 30737378 28977666 26949739 32744500 21258344 24981860 21670149 12493763 9885572 10545197 26344197
HDAC2 MTA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 12431981 30737378 26028330 26949739 20651739 21258344 26344197 12493763 11146623 21670149 24981860 9885572 12920132 17671180 18451879 20071335
CBFB SIN3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
RBBP4 SIN3A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SIN3A RBBP4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9651585 11118440 9150133 27705803 21258344 33961781 24981860 12943729 12453419 11602581 15451426 9150135
IL2 IL2RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11035066 16477002 8049354 8006584 22446627
PKN1 RHOA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 8571127 31871319 10619026 12773565 9446575 9535835
PRKAA1 GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18183946 26626483
EEF1A1 RPL12 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
IKZF5 IKZF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 25416956 10978333 33961781
PPP1CA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19036824
PIK3R2 SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
MTA2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9790534 19703393 22939629 25247294 28977666 20693977 32744500 24981860 21670149 12920132 26344197
MBD2 MTA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10444591 24981860 11102443 25753662 11297506 26344197
GATAD2A RBBP7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RBBP7 SIN3A â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
BYSL RPS25 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SOS1 HRAS â—¼   GTPASE_REACTION ✅ + 0.9 0.9 Signor 23132018
GATAD2A RBBP4 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
RBBP7 SIN3B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
BCAS2 SNRPE â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
BCAS2 SNRPD2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CBX3 STK16 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SHC1 SOS1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EEF1A1 RPS11 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CHD4 MTA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CHD3 MTA1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD4 GATAD2A â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ACIN1 SAP18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EEF1A1 RPL5 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PKN1 RHOA â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CHD3 MTA2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
DOK2 RASA1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 10799545 16189514 10822173 10428862 9478921 10508618
JAK3 IL2RG â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 7973658 16189514 27742835 7973659
ACTL6A KAT5 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CHD3 GATAD2A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CHD4 MTA2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CBFB TCEB2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
KAT5 RUVBL1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
BYSL RPS2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CHD3 RBBP7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EEF1A1 RPS2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD2 MTA2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
TAF5 TAF9 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 23292512 17355863
SOS1 HRAS â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17084389 5219305
IL2RB IL2RG â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
RBM25 SNRPE â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBM25 SNRPD2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RBM25 SNRPB â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD4 RBBP7 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 RBBP4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
EEF1G EFTUD2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ACTL6A RUVBL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
IL2RG IL2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16477002 8049354 11418623 8006584 10662798 22446627
STAMBPL1 UBC â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
HDAC2 MTA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PRPF19 SNRPB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MTA1 RBBP7 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
EFTUD2 SNRPB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MTA1 RBBP7 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 27098840 18067919 26028330 27705803 33961781 24981860 26186194 12920132
SHC1 SOS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8631299 10570290 10025673 8235613 8626525 9544989 10675333 10783152 8950973 7559490 19380743 16371368 9344843 7520523 8621459
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SMARCB1 SMARCD2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
BYSL FBL â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ACTL6A SMARCB1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8940013 6169950
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5220480 7642581
GAB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25416956 31980649 21706016 10068651 16371368 10391903 32296183 15143164 10913131 19523899 19172738 11782427 19380743 11882361 9660791 16253990 33961781 20936779
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
MTA1 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 16189514 25416956 27144666 27098840 18067919 27705803 33961781 24981860 26186194 21670149 24920672 12920132 33264408 26344197
MTA2 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 19703393 22939629 14645126 10444591 27705803 28179136 33961781 24981860 21670149 19686092 11602581 12920132 11297506 26344197
ACTL6A SMARCD1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CBX3 HIST1H1E â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SOCS3 TCEB2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MBD2 RBBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BYSL RPS11 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MBD2 MTA1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HRAS RASA1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GATAD2A MBD2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK4 CDKN1A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PRPF19 SNRPE â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
UBC USP2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL12 RPL28 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EFTUD2 SNRPD2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12485888 21725358 31980649 9126968 7514169 7744881 8235613 11453982 8662733 8491186 7629070 8940013 10570290 8112292 12213123 11302736 8662998 8195171 7597091 8810340 32062451 9129019 16371368 12149229 10049786 8626525 7650032 8950973 9488479 24189400 15812354 12441060 19380743 26551075 22057045 10477741 28690151 16713569 7516467 9733714 11827484 11964172 7537740 16520382 9019162 8663178 9797459 9032244 12577067 9927207 7524086 8995379 9886492 8294403 7559490 9434624 11792427 7798267 8621719 9541596 15688026 12898421 33961781 11370743 25416956 9544989 22974441 8939605 21706016 9083103 7535773 11505033 9175774 24430869 10080542 9020193 9045692 10356320 15888547 9254595 8561895 11707405 8647288
TAF5 TAF6 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 22939629 10523658 23292512 17355863 9045704 14580349 26344197
HRAS SOS1 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
RPL28 RPS2 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
BCAS2 EFTUD2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EFTUD2 SNRPE â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MTA2 RBBP7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EFTUD2 PRPF19 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCB1 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SNRPB SNRPE â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SNRPB SNRPD2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TAF4 TAF5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL28 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MTA1 RBBP4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BCAS2 PRPF19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF19 SNRPD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL12 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPS25 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS11 RPS25 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SNRPD2 SNRPE â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23A RPL28 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPS11 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23A RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS25 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23 RPL5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS25 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23A RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EEF1D EEF1G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
MAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9115213 10567572 12039864 10669763 15225643 11323415 21785723 9738012 11337027 10677502 23272207
MAPK1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20519948 19364816 28368408
HDAC4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18632985 18850004
CDKN1A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23443559 15169570 18850315 9658399 16962592 15232106 9632134 16189514 8622677 15695403 20102411 8242751 9464540 23007395 7626805 9106657 12383116 30193583 17556661 23543736 8756624
FRS3 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
SOS1 GRB2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 16520382 31980649 32062451 8493579 21988832 14679214 7510700 7514169 21706016 10319320 32203420 9872323 9797459 34407391 16906159 10716926 12577067 8810325 7629168 11960376 7664271 8626525 15192046 7629138 11997436 8943292 10207103 8695800 10570290 10025673 8112292 11726515 8816480 20473329 7559490 7773779 9447984 19380743 7642581 7527391 9716598 9344843 10477741 16713569 19323566 7516467 17474147 9569023 8188688 16893902 11964172 9478994 33961781 8479541 28166272 9009162
GRB2 SHC1 â—¼   PROTEIN_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
GRB2 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10467411 20936779 21988832 7537265 9872323 8576157 11960376 11278465 9045636 21706016 16713569 12112020 7799925
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
HNRNPK KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21988832 22365833 31413325 16713569 12370808
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MBD2 KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23000163 21452283 24163373 23928305 19738071
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NPM1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 8506364 7499846 8618896 15967991 8226850 8626561
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12008033 15356145
MAPK1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23597856 26637332 16627622
MAPK1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18691976 12478298 19664995 20068231
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK3 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8506364 8618896 8226850 7597029
MAPK3 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12008033 15356145
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
NONO TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 10858305 9756848 17481653
FRS3 NPM1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18452557 19459784 19456272 17086210 20454865
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
TAF4 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TAF5 TAF6 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PPP1CA TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20424263
TRIM28 CHD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18082607 11230151 24018422 16169070 21642969
FRS3 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
JAK3 SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15385932 10373548
IL2RB SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10373548
JAK1 SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25682267 10950967 16459330 10707961 10373548
LCK SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12783885 15173187 16352613
SOCS3 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10373548
SOCS3 RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11331873
YES1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18479465
SHC1 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
IL2RB SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8294403 8700888 8643566 10602027 16189514 24737791
GAB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8995358 10704825
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
SHC1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 9544989 8631299 8621483 8950973 10891441 10783152 9278309 17673906 9344843 8294403 8021500 10025673 7520523 12955078 12577067 9199344 19531499 7760801 10570290 19380743 8235613 10675333 8114695
LCK IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10214954 2047859 10602027 18348982 16189514 12200137
LCK FOXP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 28757603 26441996 30011797 24155921
LCK RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11389730 1850098
LCK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11526404 15032589 14583609 23109003 8397196 10488096
JAK1 IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
JAK1 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL2RG â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059
JAK1 IL2 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
JAK1 IL2RG â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059
JAK1 IL2 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL2RG â—¼   ENZYMATIC_REACTION ✅ 70.0 1.0 ACSN 10358772 10426994 10485906 10807786 10820393 10849428 10856136 11160275 11371360 11867689 11870632 11907067 12095053 12223527 12244150 12401408 12496409 12811837 12818165 14607946 14610620 15289500 15536084 15563472 16081783 16212621 16243976 16413922 16713974 16785506 16799562 16815076 17371980 17398124 17404308 17459805 17485448 18250477 1825141 18758473 19528259 19833085 19913445 20007590 20184663 20406969 20510870 20856220 21307131 21469115 21840487 22224781 23124025 23390297 23650441 24030977 24091328 24751819 24829413 25582338 26755705 27216177 2965306 6164929 7512720 7521688 7523571 8683106 9625766 9834059
JAK3 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11641425 19901323 20135364 17259970 12207328 10825200 11909529 15659558 12559972 9553136
IL2RG JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 7973658 7721895 8580378
JAK1 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9774657 7973658 8700888 12133952 8643566 10373548 7499411 8041779 7973659 9553136 7973657
JAK1 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9774657 15021914
PIK3R2 HRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
HRAS SOS1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
RASA1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10769036 11389730 23331499 18829532 7628625 9219684 10592173 8663024 16713569 26721396 8360177 8537347 1904555 10394594 2833817
SOS1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12628188 10208427 16713569 10913276 23331499 18454158 15507210 10592173 17673906 17496910 26721396 20133692 19141281 23132018 11560935 9447984 9690470 17084389
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
IL2 IL2RG â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RG IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RB IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 15265897 16477002 10807786 19528259 19833085 7521688 17371980 8049354 15563472 18758473 10662798 15289500 23331499 26755705 8683106 23180781 12095053 11418623 6164929 9625766 24829413 1825141 8006584 16799562 7829965 8568232 10820393 7512720 23650441 20856220 7681595 10849428 22224781 1631559 16212621 21840487 26192618 2965306 8260650 23124025
IL2RA IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15933202 15265897 8568232 8260650
IL2RG JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 7973658 7973659 18445337 10856136 16189514 10629052 15621723 7973657
IL2RG IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2 IL2RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8568232 3095922 15265897 16477002 11035066 3098894 15933202 1940342 15178252 8260650 3116143 22446627 8006584 8049354
JAK3 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 7693677 16189514 10825200 7973659 9553136 7973657
IL2RB IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8568232 15265897 11886175 15933202 15178252 1545122 8260650 3116143 8006584
IL2 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
HMGA1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8934574 8896456 10848593 10706706
FOXP3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 25567984 23275607 22806628 21458306 17028180 16873067 21955384 17586580 23954131 17922010 20429413 18324310 19172156 17416586 22579476 18779564 17430097 21654845 17632414 11483607 18759924 19564342
PRDM1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23129528 18725523 24019486 22585398 9110979 17182561
IL2 IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 6815536 3095922 15265897 12649439 16477002 15933202 1940342 17032757 15178252 8260650 3116143 8894436 1993646 8580082 8960125
RHOA PKN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8571127 12773565 16189514 9446575 10619026 9535835
FOXP3 IL2RA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12522256 17237765 17449799 21411734
FOXP3 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23144749 20554955 17028180 18606654 15466453 21036387
GAB2 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9973481 10982827 18950707
PTK6 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10913193 19304789 16179349
PRKAA1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27010499 18184930 21892142
EEF1D EEF1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 16169070 32814053 16189514 30021884 9407120
HNRNPA1 PTBP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
PRKAA1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10376603 12446767 11729179 16043647 11696579 16126727 12791703 24379783 19131647 18303014