Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RRAS2 ARAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
ARAF YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
GRB2 BCLAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
BCLAF1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
BCLAF1 RP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CLK2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CLK2 SNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938077
YWHAG DDX39B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
GRB2 DDX39B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
FXR1 SFPQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ASXL1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABI1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
GRB2 SPEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 THRAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TP53 HMGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547598 9472015
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
CBX8 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15899946
ZMIZ1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26522984
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
TP53 PARK7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23447676 23149933
ESR1 PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22430216 18414489
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
YWHAG SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
THOC5 THOC7 â—¼   COLOCALIZATION 2.0 0.8 intact 19059247 6799957
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
TP53 CASP10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14688482
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14688482
LRRK2 DYRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
CBX8 BMI1 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
NCBP3 SNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNIP1 SRPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
EIF4A3 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PIN1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
PIN1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9499405
NCBP3 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
ABI1 YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
CLK1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RNPS1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SRPK1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PNN YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CLK3 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG SRRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG THRAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ESR1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17685427 20484412
ESR1 MTA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15169784
BTF3 EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17312387
RNPS1 SRPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
ALYREF NCBP1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RNPS1 SRRM1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
GRB2 MAP4K1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
SRPK2 RNPS1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 22365833 8293266
DDX39B THOC7 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CFTR YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
SNW1 SRRM1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ARAF EMD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
CRY1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23133559 25756610
BMI1 FXR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
MYC KAT7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CUL3 MCM7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 26188516
MYC NXF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC RNPS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
BMI1 SNW1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 SNW1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19934264 33731348
SNW1 SRRM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 16159877
SNW1 THOC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 20467437
PNN SNIP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
BMI1 NCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 NCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 RNPS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
FHL1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19401155 22094188
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
DDX39B THOC5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SRPK2 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
SRPK1 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
SNIP1 CLK2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
CLK3 CLK2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
MYC ERCC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33381997 17314511 29467282
SNW1 MYC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30415952 19818711 29467282
SNIP1 NCBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SNIP1 SRSF9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 30404004 33961781 26186194
GAN CUL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 15983046 31944090
CFTR RAB5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26618866 21455491 19398555
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
LRRK2 YWHAG â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PIN1 BCL2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 11988841 11326318
CCNB1 CDK7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 33961781 26186194 11113184
SNW1 SFPQ â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20467437 12840015
NCBP1 THOC2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
BCLAF1 THRAP3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
SNIP1 THRAP3 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SNIP1 SRRM1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MAGOH SNW1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
SRPK2 CLK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34133714 23602568
CLK3 RNPS1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 32296183 33961781
CSNK2A1 SIRT1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
CCNB1 FXR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 26496610
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
DDX39B THOC3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CLK2 SRRM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 26871637
CLK2 CLK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 34133714
CLK2 CLK3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 16189514 25416956 34133714 33961781 21516116
CLK2 RNPS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956
CFTR EMD â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26618866 31324722 17110338
NXF1 SNW1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22658674 32296183 29395067
THOC5 THOC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15998806 22939629 26344197 26496610
THOC5 THOC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15998806 26496610 33961781 22939629 23222130 26344197
RNPS1 SNIP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17353931 33961781 26186194 30404004
SNIP1 CLK3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
ESR1 MTA3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18451880 31527615
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
THOC2 THOC7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15998806 26496610 22939629 23222130 26344197
THOC2 THOC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15998806 26496610 33961781 17190602 22939629 23222130 26344197
THOC3 THOC7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 22939629 26344197
THOC3 THOC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 26344197
RNPS1 SRRM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 33961781 16713569
THOC6 THOC7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 26496610
EIF4A3 SNW1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
THOC2 THOC7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
THOC6 THOC7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ALYREF THOC5 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RNF113A SNW1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ALYREF THOC1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
CLK2 SNIP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 25416956 33961781 26186194 21516116 32707033
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
CLK2 CLK3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
THOC2 THOC6 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DDX39B THOC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SNW1 SNIP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22365833 18794151 26186194 30404004
THOC5 THOC1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 23299939
THOC7 THOC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 33961781 19059247 29395067 22939629 26344197
THOC1 THOC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 26496610 33961781 29395067 22939629 26344197
THOC1 THOC5 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 7033698 19165146
THOC7 THOC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15998806 26496610 19059247 22939629 26344197
THOC2 THOC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15998806 19165146 26496610 23299939 17190602 22939629 23222130 26344197
RNPS1 SRPK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 25416956 17353931 22365833 33961781 32707033
SRPK2 CLK3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25416956 34133714 33961781 23602568 32707033
THOC2 THOC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15998806 26496610 19165146 17190602 22939629 26344197
PIN1 ZBTB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PNN RNPS1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
YWHAG ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
RRAS2 ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 12620389
ESR2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19211725 18223478 20664923
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC MCM7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 17314511 29467282 30415952
MYC MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PIN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26655473 29467282 15048125 19131971
MYC THRAP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
PRKCD PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
THOC5 THOC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15998806 22365833 19165146 26496610 23299939 33961781 19059247 29395067 22939629 26344197
THOC2 THOC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15998806 29395067 19165146 26496610 33961781 17190602 22939629 23222130 26344197
THOC1 THOC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26496610 19165146 33961781 29395067 22939629 26344197
CBX8 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 34316702 20543829 10825164 20601937 19636380 26496610 27705803 22325352 33961781 24981860 17332741 24457600
RELA PIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19458071 19668231 16950761
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
RNPS1 SRPK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17353931 33961781 23602568 32707033
SRPK2 SRRM1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 26167880 33961781 23602568
CBX8 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
THOC2 THOC5 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
THOC3 THOC6 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
THOC5 THOC6 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
THOC1 THOC3 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
RNF113A SNIP1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
THOC3 THOC7 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
THOC2 THOC3 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
THOC1 THOC6 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
THOC1 THOC7 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
THOC3 THOC5 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
THOC1 THOC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ALYREF DDX39B â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
BMI1 CBX8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
HMGB1 TP53 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CBX8 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219708 17332741
BMI1 CBX8 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 5219708 17332741
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
ALYREF THOC2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
THOC5 THOC7 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
NCBP2 NCBP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 23665581 9933612 26382858 31467278 11545740 22365833 26496610 29395067 12374755 26264872 7478990 19668212 22939629 29997244 32814053 29101316 24981860 31448526 17190602 12434151 26344197
DDX39B THOC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
THOC1 THOC5 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
SNIP1 SNW1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
YWHAG ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17353931 15324660
CUL3 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
RELA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 19233129 16022909 18761399 18191642 21224428 16453001
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
ESR1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19148464 19160418 9306964 11261829 21841772 10542244 20664923 18414489
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
GRB2 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9346925 9891069 9788432 17474147 11279207
TP53 HMGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
HMGB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
MEN1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11526476 14508515 16713569
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
PRKCD EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
SIRT1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
RELA SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20617556 15152190 24064732
SIRT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19408108 25217963 15152190 21081649
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
SIRT6 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 19135889
STK11 MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19369195 12879020 17192257 14976552
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
DLD PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21930781 17289674
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879