Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATRX H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
SMARCA5 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19092802 19234442
SMARCA1 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMARCA5 BAZ1B â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19092802 19234442
STAT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11994401
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
BCL2 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313378
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
NCK1 BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JMJD6 BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CLDN1 BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHFR BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRPF40A BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
GRB2 BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
C7orf25 BRD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BRD4 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
BRD4 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MYC BRD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23792448 22904298
BRD4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32482868
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
STAT3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11279133
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
CCND1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11279133
CDK1 NUMA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7769006 23921553
CDK1 RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12930972
CHAF1A NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CHAF1A PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
E2F1 TOP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313881
E2F1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12629508
E2F1 MCM5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 17210690
MAPK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14967450 22802261
EGFR E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16299810
HDAC1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980157 18319725
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
E2F1 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
EGFR H3C2 â—¼   COLOCALIZATION 2.0 0.8 intact 5216105 12577067
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
EP300 CCNT1 â—¼   ACETYLATION ✅ 2.0 0.8 intact 7265510 19387490
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
YWHAZ FOXO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10102273 5211323
FOXO3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056725 21752881
AR FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
SMARCD1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ASXL1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SMARCC1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MED14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SMARCA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
H4C6 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10364196 5211544
KAT5 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24069158 12782627
KAT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
MAPK3 GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22227582 11585926
MYC TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19602047 11509615
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
CDC73 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18987311
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
NPM1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NPM1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 IL7R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ NUMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10887121 8009576
AR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12933816
PIK3R1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25814554 15021914
SMARCA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20129940 8009769
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
SMARCA5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218974 16917504
AR SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 20610535
SMARCC1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 18581278
H3C2 SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7903691 20389281
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
TWIST1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20007935 16831897
JMJD6 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24667498 1001819
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 TWIST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504427 20689556
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
JMJD6 TP53 â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 24667498 1001819
TWIST1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22056872 8313152
USP7 CHFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17442268
H3C2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
XRCC6 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WDR5 CHD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7542690 20085832
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
NCK1 MED14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 ASXL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
H3C2 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19766566 8009287
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
AR KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
AR KDM4C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23698634 20610535
AR SMARCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16373397 20610535
NSD2 AR â—¼   COLOCALIZATION 2.0 0.8 intact 19481544 7103716
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
KDM4C AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17277772 29207681
H4C6 BRD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20709061 7989531
H4C6 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
PRPF40A ASXL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRPF40A UBR4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
H4C6 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
GATA1 MED16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17132730 0604494103
KDM6B H4C6 â—¼   DEMETHYLATION ✅ 2.0 0.8 Reactome 19451218 19451217
KDM6B H3C2 â—¼   DEMETHYLATION ✅ 2.0 0.8 Reactome 19451218 19451217
H4C6 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
H3C2 KDM4C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16603238 18066052
H4C6 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19766566 8009287
TRIP12 USP7 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
BRD4 TCEB1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCND1 CDK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
HDAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CHD4 EZH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
BAZ1B H31 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34079125 29568061 16252006 23319141
BRD4 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32416067 20676058 24945803 30428346
BRD4 BRD2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31753913 31239290 30554943 32416067 21555454
CDC5L MCM5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15232106 20467437 16189514
PIK3R1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16273093 5218056
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 H31 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16109717 30110629 11884585 23415232 15951563 27208796 15611041 11830591 28465257 19801601 16415179 27585400 15308690 20587414 19270680 28844863 24722339 15136563 23587423 30428346 20368990 11689448 23870121 12237408 11983172 18838386 16717280 21875947 14752096 8945521 16287840 30902546 29033323 15834423 12498683 10545121 23934153 14585496 11691934
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 CHD4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 26546801 30110629 32699137 15189737
H31 HDAC2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11850410 12626569 24722339
NSD2 H31 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25494638 19481544 34079125 34271259 25281560 26912663
BRD3 BRD4 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BRD9 SMARCD1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MED12 MED24 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
BRD4 FOXO3 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
H3F3A SMARCD1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
MED14 POLR2H â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
BRD3 ATAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
ATRX XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30585729 23329831
ATRX H32 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21666677 21666679
NSD2 BAZ1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22751105 31248990
CRK BRD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 32416067
AT1A1 BRD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31239290 19293945
CH033 BRD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21900206 31239290
CDC73 BRD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26659056 32416067
JUN BRD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31239290 25609649
BRD4 RN219 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31239290 31413325
BRD4 LARP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26659056 32416067
BRD4 RTF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32416067 26344197
BRD4 H2B1C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31239290 34079125
BRD4 MED12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32416067 16109376
MYC CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CDC5L CDK9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 26209609
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CTR9 CDK9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
CUL4B RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
CUL4B WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
H2B1C DMAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
DMAP1 BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 26344197
NCK1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 8662998 5221064
HEXI1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
ERG EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 28536097
EZH2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
MTA2 LARP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 29845934
CDC73 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 26687678
MYC RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SMC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC TOP2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RFC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC RFC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC CHD8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RFC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
NSD2 NUMA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22751105 31248990
RFC1 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30585729 26344197
H31 SMC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26527279 29568061
H31 TOP2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20504901
JUN XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 30585729
XRCC6 ZCH18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29298432 30585729
CUL2 RPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30349055
JUN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17056544 25609649
JUN H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 30804502
H4 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 30804502
NEDD8 MCM5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18247557 18274552
HIST2H3C MLLT1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
AFF1 CCNT1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
CTR9 CCNT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26659056 26496610
ZCH18 CTR9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 29298432
ANDR CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
ANDR BRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24759320 28805820
BRD3 BRD9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
PI42A AFF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CAMKV AFF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ANDR BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24759320 28805820
CAMKV BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BRD3 NSD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRD3 CHD8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
PI42A RTF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ANDR MED24 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 19762545
ZCH18 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29298432 30804502
PI42A JMJD6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HIST1H4A WDR5 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HIST2H4A WDR5 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
SMARCA4 TCEB1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST4H4 SMARCD1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST1H4A SMARCD1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST2H4A SMARCD1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
H3F3A WDR5 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HDAC1 HIST1H4F â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
BRD2 BRD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ATRX H3F3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATRX HIST2H3C â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HIST1H3A NPM1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 H3F3A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 HIST2H3C â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 HIST2H4A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 HIST1H4A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
H3F3A WHSC1L1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3C WHSC1L1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST4H4 WHSC1L1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H4A WHSC1L1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H4A WHSC1L1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3A MLLT1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BRD3 GATA1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ATAD5 RFC4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31160570 33961781 20147293 24981860
RFC5 ATAD5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31160570 24981860
ATRX H4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 30804502 23329831
F90A1 BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
MYC BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29172540 30415952 32416067
NUMA1 BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31239290 32416067 30554943 26344197
CP1A1 BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
GPSM1 BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CDC5L BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31239290 20467437 32416067
XRCC6 BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31239290 30585729 32416067
PI42A BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913 31239290
BRD4 MED1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19766566 33567268 31239290 20098423 30554943 32416067
BRD4 HEXI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18039861 16109377 32416067
BRD4 NSD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31248990 31753913 31239290 30554943 32416067 21555454
BRD4 DMAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32416067 30554943 26344197
BRD4 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 32416067 16109376
BRD4 PR40A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 31239290 15231748 30554943 32416067
BRD4 ZCH18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32416067 30554943 26344197
BRD4 MED14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 33567268 32416067 16109376
BRD4 CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31239290 30554943 34079125 32416067
BRD4 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 32416067 16109376
BRD3 CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 30554943 31753913
BRD2 CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 30554943 31753913
CBX3 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 33022573 27705803
CCND1 RFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10353443 21654808
CCND1 CDK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 33961781 7903056 21654808
CDK9 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11689688 12861003
DMAP1 MYC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 20946988
EP300 RPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16916636 33742100 9710619
KAT5 STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12551922 16713569
MYC CTR9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 29467282 26687678
GPSM1 NUMA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
JUN TOP2A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8387155 25609649
VHL RPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28775317 12604794 30349055 18285459
PI42A CCNT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
EZH2 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28486105 28068325 24981860 26344197
F90A1 BRD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
PI42A BRD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913
MED14 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9989412 18418385 33961781 24981860 22939629 26344197
MED17 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED17 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
F90A1 BRD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
PI42A BRD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913
F90A1 KDM5B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PR40A ZCH18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 29298432 33961781
JMJD6 PR40A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 21555454
JMJD6 H4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 29373688
HIST2H3C SMARCA5 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CBX3 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HIST4H4 SMARCA4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HIST1H4A SMARCA4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HIST2H4A SMARCA4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CHD4 SMARCA4 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC2 SNAI1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
H3F3A PHF2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST2H3C PHF2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST1H3A YWHAZ â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST1H3A PHF2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST1H2AB HIST1H2BB â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CCND1 CUL1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
FOXO3 YWHAE â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KAT8 TP53 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EGFR AT1A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24797263 16799092 28065597
SNAI1 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28296173 25314079 32494626
FOXO3 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19592618 25609649 11896584
EP300 XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15023334 33742100 21988832
HIST1H4F NPM1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6613464 18451879
PAF1 CTR9 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
ANDR ERG â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22722839 20478527
EZH2 H31 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 16431907 16224021 33479123
MED23 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
CHD8 ANDR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33640491 20308527
NSD2 H4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25494638 31248990 30804502
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIST1H2AB HIST1H4F â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIST1H2AB HIST4H4 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIST1H2AB HIST2H4A â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIST1H2AB HIST1H4A â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CHAF1A RBBP4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
H3F3A HIST1H2AB â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST1H2AB HIST2H3C â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST1H2AB HIST1H3A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
H3F3A HIST1H4F â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4F HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H2BB HIST2H3C â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3C HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H2BB HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H2BB HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H2BB HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
H3F3A SMARCA4 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CBX3 CHAF1A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ATRX H31 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 33961781 29568061 21421568
CAMKV BRD4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
CBX3 H4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30804502 27248496 24981860 21888893 14578449
CCND1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11279133 15659654
CDK9 CCNT2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 34026424 25189618
BRD2 E2F1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10965846 17111193
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
EP300 MCM5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
GRB2 H4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19380743 31980649 12577067
KAT5 H4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16287840 10096020 30804502 15005629 21668587 16844118 24525235 32814053 25865756 32238831 19783983 20351180 22100137
SMARCD1 SMARCC1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
HDAC1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15653507 22750444 15870198 22116549
CRK NCK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8879209 9837978
VHL EGLN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22286099 17986458 26215701
SPOP BRD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29996942 31776466 28805820 28805822
CAMKV BRD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
ANDR EZH2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24457600 27728805 30628724
HEXI1 TF65 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 12581153
CAMKV ZCH18 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MED12 MED17 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BRD4 HIST1H4F â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
AR SPOP â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BRD4 BAZ1B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30554943 32416067
BRD4 SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28805820 34133717 34588438 28805822 31559706
CBX3 XRCC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21888893
CDC5L CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20467437 21145461
CDK9 CDC73 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26659056 17643375
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
EP300 H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11163245 16096645 30804502 16109717 25728767 11884585 15951563 15611041 11830591 28465257 16415179 11689053 15308690 28844863 26625199 15136563 17982102 18397880 12499368 23587423 20368990 11689448 12237408 11983172 16717280 14752096 22100137 14612423 8945521 16287840 18418072 30902546 15834423 23934153 14585496 11691934 10607594 16332960
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
MYC HUWE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17314511 16269333 26279298 18488021 29467282 31677785
SMC1A RFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16438930 26344197
WDR5 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
H31 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 11850410 31874856 26527279 24722339
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
ANDR SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24508459 30244836 19762545 33158056 25274033
TWST1 TF65 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21983900 12553906
CBX3 HIST1H4F â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
BRD4 EP300 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
HIST4H4 WDR5 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
HIST1H4F WDR5 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
HIST2H4A SMARCA5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HIST4H4 SMARCA5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HIST1H4A SMARCA5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HIST1H4F SMARCD1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CHD8 WDR5 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST4H4 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
HIST4H4 SUPT16H â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
HIST1H4A SUPT16H â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
HIST2H4A SUPT16H â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NEDD8 TCEB1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
BRD4 ATRX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31239290 30554943 32416067
BRD4 RPB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31239290 30554943 32416067
BRD4 H32 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31239290 18500820
BRD4 TOP2A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31239290 30554943 32416067
BRD4 CCNT2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24360279 32416067 16109376
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
CDC5L TOP2A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11101529 20467437
CDC5L ZCH18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 22939629 29298432
CDK9 PAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26659056 24837678 21873227
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
GATA4 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18252717 27208796 11481322
LARP7 CCNT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18281698 26725010 33961781 27684187 18483487 24367103 29845934
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC MED12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12660246 29467282
MYC RFC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 30415952 29467282
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
TF65 SNAI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19411070 25314079
HDAC1 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 27705803 33961781 26186194 33022573 22689669
CDC73 RPB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16024656 26659056 15923622 15632063
HEXIM1 CCNT1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 6613869 18483487
HDAC1 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HDAC2 H4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12626569 24722339 30804502
VHL NEDD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16503656 17353931 15060148 18323857 11024059
MED12 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 20133760 26344197
MED12 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 26496610 23563140 33961781 24981860 27684187 20133760 26344197
MED12 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760
MED12 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760 26344197
MED1 RPB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24981860 15989967
MED14 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9989412 18418385 24882805 33961781 24981860 22939629 26344197
MED14 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 24882805 24981860 22939629 26344197
MED16 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24882805 24981860 33961781 22939629 26344197
HEXIM1 LARP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HIST1H4F SMARCA4 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED12 MED16 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF1 MLLT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF1 CDK9 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CHD4 SMARCC1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HIST1H4F KAT8 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED16 MED24 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ATRX HIST1H3A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC1 SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDK1 EZH2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED14 MED16 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CCNT1 LARP7 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
GPSM1 NUMA1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRD4 CCNT1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
CDK9 MLLT1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
CDK9 RPB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24837678 12052871 12036313 15328539 11575923 12861003 21030982 14627702 16735508 26659056 21873227 15169877 14580347 17234882 12591939 22379099 22592529 23064645 15713661 18391197 11278802 15009212 18566585 20106982
CUL1 E2F1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10559858 11245432
E2F1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10734134 9468140 17980157 26468294 9468139
MYC TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15616592 16713569 28628118 28205554 12027803
EZH2 SNAI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 24903147 18519590
SNAI1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21685935 25314079 20534591 14673164 34026424
JUN STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
RTF1 CDC73 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16024656 20178742 15923622
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
NSD2 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18172012 18156491
BRD3 SPOP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED23 MED16 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25281560 24882805 24981860
MED23 MED24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25281560 26344197
CCNT2 HEXI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 12832472 33961781 26186194 29845934
KDM5C H32 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17320161 17468742 17320160
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST1H2BB HIST1H4F â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST1H2BB HIST1H3A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED1 MED17 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDK9 LARP7 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED1 MED16 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED14 MED24 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MED1 MED24 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CHAF1A HIST1H3A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RFC1 SMC1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EP300 HIST1H2BB â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED12 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED23 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED12 MED14 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED17 MED24 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
TWST1 BRD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31311807 24525235
BRD4 RFC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30554943 12192049 32416067 31753913
BRD4 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33640491 24759320 28805820
BRD4 BRD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31753913 26344197 30554943 32416067 21555454
BRD4 RFC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24981860 30554943 12192049 32416067
BRD4 RFC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24981860 30554943 12192049 32416067
AFF1 CDK9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 32479599 20153263 33961781 21729782 21030982 23602568 26186194 27684187 23455922 24367103
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
DMAP1 KAT5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27153538 33961781 26186194 14966270 20946988
KAT5 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10364196 11994312 11591700 16713569
KAT5 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12776177 15572685 18003922 35140242 30415952 20946988
HEXI1 LARP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18281698 26725010 25470060 26186194 33961781 18483487 24367103 29845934
RFC4 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 17353931 30415952 29467282
MYC XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
MYC CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
SNAI1 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21685935 26794444 25314079 20562920 23011797 14673164 34026424
HIST1H3A SUPT16H â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC1 TOP2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11062478 11136718
H31 XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 29568061 21187428 33961781 34079125 26527279 25281560 20504901
VHL CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6542648 18323857
WDR5 KAT8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 20479123 24981860 27705803
CCNT2 HEXIM1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC1 NSD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18172012 16197452 18156491 22972034
HDAC1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15640443 11994312 16713569 15835920 26468294 34585037
MED12 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30099503 26496610 20133760 33961781 25281560
AFF1 CCNT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20153263 21030982 27684187 19956800 24367103
CHD4 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9790534 28977666 27705803 32744500 33961781 24981860 21670149 22939629 9885572 26344197
CHD4 H31 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32251276 24576085 32744500 26527279 21278251 31970415
PAF1 RPB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24837678 20178742 16024656 15923622 16491129 24360965
MED14 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9989412 18418385 24882805 33961781 25281560 26344197
H31 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 27098840 16728976 19410545 14718166 31435636 11850410 29263092 19410544 33961781 26527279 16622419 29568061 19498464
SPOP BRD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28805821 31026449 28805822 28805820
H32 H4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27248496 29104064 26167883 30021884
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
BRD4 CDK9 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EGFR PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED14 MED17 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
BRD4 DMAP1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
POLR2A RTF1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MED1 MED14 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
HIST1H4F KAT5 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CDK1 ATAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31875566
EZH2 ATRX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9499421 25417162 27634302
MAPK3 BAZ1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19776015
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
E2F1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11559537 18319725 11704823
C8orf33 BRD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MESD BRD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
H31 BRD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19766566 30554943 29568061 32416067
TF65 BRD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19103749 22645123 23686307
BRD4 CCNT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18039861 33567268 16109376 31753913 31239290 16109377 24360279 17690245 32416067 30554943 24367103 21555454
BRD4 JMJD6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33567268 33961781 29176719 24360279 32416067 30554943 23455924 21555454
BRD4 CDK9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18039861 19766566 26659056 21555454 24367103 17643375 31753913 31239290 16109377 32669118 24360279 17690245 32416067 30554943 16980611 16109376
BRD4 RFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31239290 30554943 12192049 32416067
BRD4 RFC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12192049 31753913 24981860 30554943 32416067
BRD4 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22509028
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ANDR CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15558026 16713569 11328859 16461912 10344732
FOXO3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12391153 21294163
EGFR CDK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 23956138 24658140 25402006 18271526 15657067
CDK9 LARP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26659056 32707033 17643375 20562857 18281698 26725010 33961781 26186194 23602568 27684187 23455922 18483487 24367103 29845934
CDK9 HEXI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17643375 22948151 20562857 15713662 27684187 23455922 16980611 25470060 15169877 14580347 16109377 18483487 24367103 29845934 12832472 15713661 22483617 15201869 32707033 33961781 24360279 26186194 24981860
E2F1 SMARCA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
E2F1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24755270
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276347 21625432
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
NCK1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 9362449 24658140 10026169 8662998 16273093 25402006 1333047
EGFR CRK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16729043 9642287 31980649 10595738 22973453 24658140 11956190 16273093 9617486 25402006 12198159 8875975 9480911
EGFR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 23956138 20145033 21573184 25402006 15485908 15657067 14966128 9756944 18258752 15284024 24189400 24240702 25754235 24135280 15950906 24658140 12873986 20067773 10358079
RELA EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17881446 23379415
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 TF65 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11585920 25074812 15171256 11533489 16291753 23999430 16135789 12403783 12456660 11567019 9096323 25400040 20154269 17982102 18397880 18280497 12419806 21187066 12471036 23811396 16713569 10235267 15192014 17692505 20333651 21483817 12960163 29706626
FOXO3 PRKAA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24257750 22848740 17711846
MAPK3 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19282669
PRPF40A LARP7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LARP7 HEXIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18483487 30824372
CCNT1 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12944920 19818711 11673469 17700062 29467282 30415952
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC RPB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 23079660 12660246 29467282
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RFC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
AR PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22740037 12063252 20610535
RELA SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18477483 19538137 17665043
PRKAA1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19923321
TF65 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 19345327 14593105 23335796 12057007 31802034
ANDR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12804609 11322786 16713569 11751884
NFKB1 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12057007 25241761 16713569
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
KAT8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17189187 16601686
MTA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11099047
CUL2 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 22086907 28514442 9751722 10823831 15060148 11865071 21942715 27697924 20049704 26743088 11779168 17439941 12604794 9122164 21145461 15611064 19030229 21685897 12048197 10421634 28775317 15601820 10449727 24469044 11384984 10587522 18173839 22286099 17339318 16261165 16611863 23401859 15966899 22234250 9447969 17353931 26751167 18323857 25661653 33137104 11024059 18187417 18523483 10318914 26735018 24981860 33961781 31444342 26846855 17132228
WDR5 CHD8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 20085832 24705355 18378692
WDR5 H31 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17041588 24788516 16829959 25666610 15960974 16946699 33022573 16600877 32207970 16829960 25330109
CDC73 PAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18469135 20178742 15632063 20305087 26496610 15923622 19136632 27462432 22939629 19410543 29774127 21726809 16024656 22863883 33961781 24981860 26186194 26344197
CDC73 CTR9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 29774127 18469135 20178742 22532828 21726809 26496610 15632063 16024656 22863883 15923622 20305087 26186194 33961781 24981860 22939629 19136632 26344197
CHD4 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25247294 32744500 21258344 11102443 28977666 9885572 26496610 20585571 10220385 22075476 21670149 22939629 23752268 27616479 9790534 9804427 26949739 20693977 33961781 24981860 12920132 26344197
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
MTA2 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 31980649 19703393 22939629 30737378 20714342 26949739 10444591 21258344 24981860 12493763 19686092 11102443 12920132 18451879 11297506 26344197
HDAC2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 9790534 9804427 11003653 22939629 30737378 28977666 26949739 32744500 21258344 24981860 21670149 12493763 9885572 10545197 26344197
HDAC2 TF65 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27012186 25241761 20388487 12419806 12138131 11395507 17827154 20065107 10958685
ANDR JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 16713569 8798722
SPOP CUL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22911784 21577200 21988832 19256485 28216678 29160310 25011449 30244836 16524876 22013077 22632832 33961781 25278611 19261606 31559706
RELA STC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
RELA IL7R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
MED1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 26496610 20098423 23322298 23563140 33961781 24981860 27684187 20133760 26344197
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
HEXI1 CCNT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12832472 15855166 15940264 27684187 15169877 14580347 17724342 16109377 18281698 33961781 26186194 19387490 15201869 18483487 24367103 29845934
PAF1 CTR9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19410543 18469135 30228257 20178742 21726809 26496610 16024656 33961781 20305087 24981860 22939629 26902284 26344197
MED1 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 9653119 33961781 24981860 22939629 20133760 26344197
MED1 MED23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20133760 20098423 33961781 25281560
MED1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12218053 33640491 16713569
MED1 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 33961781 24981860 17967894 20133760 26344197
MED1 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 9989412 18418385 15989967 20098423 33961781 24981860 22939629 20133760 26344197
MED1 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20098423 33961781 24981860 22939629 17967894 20133760 26344197
MTA2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9790534 19703393 22939629 25247294 28977666 20693977 32744500 24981860 21670149 12920132 26344197
C7orf25 EZH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 KDM6B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23179372 22014533 23932971
PAF1 RTF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19410543 18469135 20178742 16024656 24981860 22939629 26344197
KDM5C H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
KDM5B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
KDM6B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24561908 20123895
KDM4C H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 29207681 18022353
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HDAC2 SMARCA5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
H3F3A HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CHD4 HIST1H4F â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
HIST1H4F WHSC1L1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
HIST1H3A WHSC1L1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
HEXIM1 CDK9 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613869 18483487
LARP7 CDK9 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613869 18483487
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ATAD5 RFC2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
NEDD8 TCEB2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BAZ1B SMARCA5 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HIST1H4F RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
DMAP1 KAT5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
CDK9 HEXIM1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CDK9 POLR2A â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
EP300 HIST1H4F â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
FOXO3 YWHAZ â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
CTR9 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
H4 MCM5 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 19862764 25963833
CHD4 MTA2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MED14 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CDC5L TCERG1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
RFC2 RFC3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 9488738 26344197 24981860
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
RPB1 CTR9 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 16024656 26902284 26496610
BRD3 BRD2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 30554943 31753913
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD4 RBBP4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
RTF1 SUPT16H â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HIST1H4F SUPT16H â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MED1 GATA1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11724781 17132730
EZH2 RBBP4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 21123648 26496610 27705803 20123894 34518534 28068325 33961781 24981860 27634302 24457600
H4 RBBP4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 27098840 30804502 12628926 19862764 8858152 29104064 27248496 9427644 33961781 24920672
RBBP4 SMARCA5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
ATAD5 RFC3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
KAT8 WDR5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
BRD4 RELA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CCNT1 HEXIM1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RBBP4 SMARCA1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
ATAD5 RFC5 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
H31 CBX3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24576085 16415788 34133717 26527279 24981860 20011120 15136563 33097091
RFC3 RFC5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 24981860 22939629 26344197
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
PAF1 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
HDAC1 H4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 30804502 10220385 27248496 26496610 14578449 24722339
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CTR9 POLR2A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
CTR9 RTF1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18469135 20178742 16024656 22939629 26344197
SMARCC1 SMARCD1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CHD4 HIST1H3A â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CBX3 HIST1H3A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
BRD4 H4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19766566 12840145 30804502 27248496 24525235 18500820 29176719 24361270 30554943 32416067
CDK9 CCNT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9499409 11145967 15328539 17643375 20562857 9491887 20305087 15713662 19387490 11713532 27684187 14627702 23455922 16980611 26659056 15107825 12588988 12944466 14580347 20153263 22959624 16109377 12115727 21729782 23602568 11282025 30649429 19914168 18483487 24367103 20535204 12832472 19818711 12894230 9872325 23064645 30652970 15713661 21697490 22483617 22939629 32707033 11713533 15528190 15546612 10958691 10617616 10574912 18566585 10465067 24981860 33961781 11689688 17700062 26186194 26344197
CDK9 CCNT2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32707033 9499409 16331689 18566585 17643375 10465067 33961781 24981860 21729782 26186194 23602568 11282025 27684187 23455922 11713533 26344197
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
CRK GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 8810325 10962563 8662907 19380743 10970810
RFC1 RFC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9488738 14681455 15655353 18245774 22939629 26344197
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
RBBP4 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 9520398 19703393 31435636 9150133 10444591 21258344 12943729 11102443 9885572 27068747 10471499 26496610 34518534 20127688 11171972 10734134 11470869 20585571 10220385 12091390 17643391 21670149 11602581 17827154 22939629 9150135 23752268 16713569 9790534 27705803 19686092 24981860 33961781 11302704 11118440 15451426 12920132 26344197
HDAC1 MTA2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 31980649 19703393 10444591 21258344 12374985 17956988 11102443 27068747 26496610 20127688 11171972 11297506 20585571 21670149 11602581 22939629 18451879 23752268 9790534 26949739 16645043 22863883 28179136 27173435 24981860 33961781 19686092 12920132 26344197
HDAC1 TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 27012186 16189514 30670829 16713569 12419806 17000776 17962807 15192014 16291753 16483679 11931769 11564889 17827154 20001970 21983014
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
NFKB1 TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20547752 8255759 27609421 29439025 16740634 21988832 24634218 14645533 11970949 35140242 15799966 25609649 15660126 21544861 29084252 14743216 8246997 34100597 22139845 17962807 9722548 2050119 22808155 20154269 21270162 17982102 24175631 25355951 23687337 11976329 15657065 8428580 20237821 12414801 10498867 22261743 16204234 16105840 14690596 11880271 33060567 8798655 16319923 21483817
BRD2 H4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19766566 30804502 14731392 20709061 27248496 31753913 17148447
MTA2 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 19703393 22939629 14645126 10444591 27705803 28179136 33961781 24981860 21670149 19686092 11602581 12920132 11297506 26344197
CTR9 SUPT16H â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PAF1 SUPT16H â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
BRD4 JMJD6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BRD4 WHSC1L1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
HIST1H4F SMARCA5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6613869 18483487
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
RFC1 RFC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 22939629 14681455 33961781 18245774 9092549 26344197
RFC1 RFC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 14681455 33961781 18245774 22939629 26344197
BRD2 HIST1H4F â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
HIST1H3A HIST1H4F â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
PAF1 POLR2A â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
ATAD5 RFC4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL2 TCEB2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDC73 RTF1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RFC3 RFC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9488738 8692848 14681455 18245774 22939629 26344197
RFC2 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9228079 9751713 28514442 9488738 22939629 8692848 15655353 33961781 24981860 16582606 9092549 26344197
RFC3 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 32296183 9488738 22939629 8692848 33961781 9092549 26344197
CDC73 POLR2A â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
H31 H4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 8598932 25416956 30804502 23319141 27248496 16622419 19498464 20080577 14578449 29568061 21724829 19410544 26527279 18571423 25533843 19766566 22828868 14718166 20739937 33961781 20498094 34079125
CCNT2 CDK9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CTR9 RTF1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL3 SPOP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAF1 RTF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RFC1 RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 CTR9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RFC2 RFC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
TCEB1 TCEB2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CTR9 PAF1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RFC3 RFC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL3 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
BCL2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
GATA4 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18653721 17098826 19602725 16469847
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
RELA BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 19233129 16022909 18761399 18191642 21224428 16453001
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
AR BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17655826 11567031 23160675 20610535
E2F1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17404573 11559537 12679318
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
STAT3 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 12400004 15805299 20514402 15184887 17997399 18320073 20880395 17089128 20446017 20422978 18981713 21344490 19287190 19103760 20043094 16144938 20233902 21172343 18839277 14523036 10626893 19926637 21435102 22504301 11431352 21385902 22313388 16048438 22984561
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
CDK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24097825 24677263 23638364 19917720 27231850 11774038 11326318 10766756
H4C6 BRD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27991587 24361270 12840145 18500820 24525235 19766566
BRD4 CDK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17690245 24832049 19723344 16109376 23596302 23027873 26659056 18971272
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
RELA CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17673602 18226221 10464245 18566231 19800042 18174238 15755876 18341653 11861406 20103608 12894581 17098279 22306268 20922712 16998474 10409765 19766095 15756023 21056029 22835384 17407600 15870875 18184402 17944672 15856023 20538607 19263436 16453001
NFKB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17673602 10464245 18566231 18341653 11861406 20103608 12894581 17098279 22306268 10409765 19766095 15756023 17407600 18184402 17944672 17008396 15856023 20538607 19263436 16453001
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
STAT3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16510571 19880237 17997399 15469392 16651438 21163886 22566696 16912181 22349830 16384639 12147685 21344490 20160059 19506034 20332458 23329648 11114718 17761947 22218594 15994929 21172343 18988190 18177723 24499623 21435102 19926637 18184402 17344214 22313388 23950841
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
HDAC2 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799 15713663
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CDK1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17218262 17303408 17660363 18414028 18590585 7575488
CDK1 MCM5 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
E2F1 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 7623816 14618416 12760745 11799067 8137237 12629169 17108174
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
CDK1 NUMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 26832443 24241204 23921553 24109598
CDK1 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 21658600 12468530 16103124 17570479 26829474 18669648
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7575488 18590585 17303408 8087847 27175585 17570479 17660363 15279786
CDK1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 25841987 34381492 25691891 27941792 27653691 23549878 25800736 22187039 23241245 25038756 25334066 22964433 27716745 20935635 21131960 29576612 33593912 21123648 23438432 21659531 26552009
CDK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 31980649 8360196 23956138 15901825 28150246 18271526 15657067 24658140 25402006 15302935
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK9 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 22053051 20222012 25023704 14662762 10364292 20106982 18066052 30135578 24385927 18644870 18329373 14517250 20932174 12052871 20226668 19575011 8416977 11575923 16735508
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
E2F1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 14532106
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
EGFR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17496910 26918608 7797556 25241761 19531499 16273093 8662998 14967450 16713569 21701776
EGFR NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1333047 23331499 31980649 10026169 16273093 9362449 8662998 24658140 25402006 15951569 9843575
PRKAA1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11020388 21940946 12379484 15006641 12590608
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
FOXO3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16061480 17522055 18687691
PRKAA1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17900900 17711846 22848740 29445193
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
KAT5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12551922 16713569
KAT5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11591700 10364196 19150978 11994312 16713569
KAT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12776177 10096020 32814053 24525235 16844118
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
MAPK3 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12721286 14517250 14662762
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 TWIST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21502402 18775330 8226933 9604935 8388392
MAPK3 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15967790
MAPK3 MED1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12356758 16314496
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
NPM1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
NCK1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
TP53 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10321740 19763735 21057544 18661553
STAT3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 24218138 23963458 15793565 16293640
IL7R PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9233603 7522165
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
RFC5 RFC2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 28514442 9488738 8692848 33961781 24981860 22939629 26344197
RFC5 RFC4 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 16189514 9488738 25416956 22939629 28514442 29892012 32296183 26264872 8692848 33961781 24981860 30021884 9092549 26344197
SMARCA1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23609547 24285714 20015969 17023429
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
SNAI1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 TWIST1 â—¼   DOWN_REGULATES ✅ - 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
STAT3 TWIST1 â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
STAT3 TWIST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23161342 17909010 24491388 23623921 23492367
HDAC2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15653507 25241761
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
STAT3 TWIST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21883379 25814554 22945800 22006115 18832382 16831886 18297062 19412634 21317430 23623921
HDAC1 TNF â—¼   DOWN_REGULATES ✅ - 15.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15465827 15644117 16878026 17404308 17485448 21234400 22796940 23390297 7594497
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
RELA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 136.0 1.0 Omnipath 26596471 17707233 20817730 12686724 27075886 21765477 21537341 19530226 17390058 18077329 15064230 20617556 8805669 17351769 23335080 21573233 17292554 16285952 9916895 11749970 7895918 17496784 12628924 23857586 12657243 15857826 12471036 11259437 16433741 9831247 20237317 15465827 26023919 22661093 10748079 15013838 17350185 10754326 15470505 11827962 20139176 26408955 22901690 18772140 21108432 22742857 23195252 18362169 24012417 11312646 17442180 9281604 10079106 11297551 15081318 22718766 24908318 8219230 26004152 11094063 11490006 9916692 16483936 18057724 16569682 22138107 18467438 20547752 22723832 19846753 17407192 20221401 19854828 20534538 7876168 16707469 12117498 20544543 23178569 15812247 21138578 12610112 25888873 16916598 16040075 28039105 14749357 20066113 19285436 25161822 22388040 14960579 20195282 16199883 15543947 23971673 10551799 11290773 22798670 22021035 20722069 20221720 27338466 19385047 12058956 26997758 25690886 7624137 20686703 26114754 14976218 10485496 17607667 8622636 11007957 18285351 10837498 11739517 18719026 17268554 17085785 17142966 10963848 9742085 23042817 27534992 10553096 26516703 20696864 10201927 16850160 8679226 21098092 20097764 9129150 17082635
TNF RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 15192014 27329558 22240205 15833743 19351843 28187781 15841081 28107185 28373828 26999213 24386331 24957606 26179215 21572963 18258304 28317833 29441018 10722927 19596989 28423685 12881425 25118327 24036851 28089769 21904602 24141032 10938077 30201812 20691659 24166907 19789307 19393267 22768286 26310932 19411070 23789107 28790310 29708974 20507904
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
MED1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15848166 9444950 16713569 11118038
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
TWIST1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 34881782 12553906
NSD2 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TCEB2 CUL2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 CUL2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RELA CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
TCEB2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
SPOP CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21988832 23331499 19256485 28216678 21577200 25011449 34599168 22911784 15897469 22013077 16524876 19261606 25278611
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
AR MED1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17483314 21593191 24778216 23887938
NSD2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19481544
KAT8 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19056256 16024812 15923642 20479123
H4C6 BRD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14731392 20709061 12776177 17148447 19766566
EZH2 ASXL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19934320 18687996 24771265 24132643
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462