DGKZ
|
SAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
DUT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19015155
12096336
|
FOXO3
|
TXN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20398632
19592618
|
FOXO3
|
SCP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17522590
|
STAT1
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15784679
|
EHMT2
|
PLOD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TP53
|
SAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TP53
|
COX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
AURKA
|
TP53
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
14702041
19121998
|
TP53
|
SMAD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21900401
|
TP53
|
HPSE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16474844
16901744
|
TP53
|
PRDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20594067
20557878
|
TP53
|
TXN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18945670
16096367
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
GPX7
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HK3
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TXN
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19737086
|
FGFR2
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15863030
11353842
|
ESR1
|
SIAH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18414489
16141343
|
ATP6AP1
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FASN
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTT
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESR1
|
HSD3B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20410197
18511507
|
ESR1
|
HSD17B3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16627580
17158782
|
ESR1
|
CKB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17272396
10411295
|
ESR1
|
CYP2C9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24960263
21493749
|
GYG1
|
GBE1
|
â—¼ GLYCOSYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8613547
22248338
|
F9
|
GGCX
|
â—¼ CARBOXYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
3667614
2738071
|
GYS2
|
GBE1
|
â—¼ GLYCOSYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15452297
8613547
|
GBE1
|
PGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HIST1H3A
|
HIST3H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
FOXO3
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ESR1
|
PLOD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25604459
31527615
|
HSPB8
|
SETD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RSBN1
|
SETD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
WDR37
|
SETD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
GPX7
|
NFS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
GSTM3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23576398
31527615
|
ESR1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21761334
31527615
|
LDHA
|
LDHC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
RSBN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33731348
31527615
|
PLOD3
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
16189514
25416956
25910212
26028330
|
AURKA
|
SETD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MDC1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28973861
16186822
|
ESR1
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21984853
31527615
|
HTT
|
SETD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
PTEN
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
ESR1
|
STAT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25303530
31527615
|
IDH2
|
IDH3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ESR1
|
FOXO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CLK2
|
SETD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
23602568
|
ESR1
|
FOXO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18312651
11435445
|
GSTA2
|
GSTA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
AURKA
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
NUDT5
|
PYCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
PRDM2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15282304
19746436
10706618
|
SMAD3
|
FOXO3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15084259
24920680
21532621
|
CBX8
|
PCGF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21282530
26687479
27505670
27705803
33961781
24981860
|
ATP6V1E2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
GPAA1
|
PIGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11483512
12802054
12052837
26496610
|
RAD51
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
FOXO3
|
PIK3CA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19299143
18644865
|
STAT1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24655378
14602726
|
TP53
|
GSTP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18505928
|
STAT1
|
MAN1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
ESR1
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21761347
21761334
18497064
|
ESR1
|
CYP11A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11500981
20410197
18511507
|
GAA
|
GYG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
5264799
3049072
8420990
|
NDUFB11
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
RAD51
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
RPA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
NDUFA12
|
NDUFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
FOXO3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24062311
16807346
16809346
17575143
|
FOXO3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18644865
10783894
16288288
20673124
11094066
17646672
15509806
11994454
11154281
|
FOXO3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11435445
15367686
16807346
18312651
|
PTEN
|
RAD51
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10753747
11747822
12040186
15721744
16288286
16982858
17218252
17218262
18716620
19847259
22179046
22465479
23732914
24254977
25364523
|
TP53
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17513613
16322760
20802511
16398215
18769160
|
TP53
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
8617246
11002423
16713569
16322760
16983346
9380510
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
TP53
|
HTT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22399227
15996546
16978870
16278683
|
TP53
|
FASN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12734185
19861536
|
TP53
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22957312
15843377
12917634
21637289
17344317
12839924
11545734
18172008
19173293
20554748
19079342
14984207
|
TP53
|
GLS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22307140
24330717
20351271
20378837
|
AURKA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
24173284
22864622
25217103
24089029
16713569
19413330
25848977
17999753
23565200
25333414
23201157
16552184
10884347
1956339
26186194
29455673
15469940
15749021
18974145
21502403
17287340
28043820
22396649
92065884
12198151
27933271
22852086
12064478
30266789
25398437
17259342
22350019
25634113
14702041
|
TP53
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21336307
18431400
18339852
12620407
17409411
18172008
17823410
16713569
21518799
21483453
|
TP53
|
HTT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18431400
32814053
16713569
10823891
|
FGFR2
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17496910
11447289
19615955
16488589
6321473
11997436
12040186
19568798
15567848
15173823
14585353
15199124
|
SMAD3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11555647
23331499
|
PTEN
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16288286
10648629
17218262
12040186
15584861
|
NDUFS1
|
NDUFA12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA12
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFA12
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA12
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS1
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
KMT2D
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
16603732
|
GGCX
|
F9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11133752
31226734
|