Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC BRD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23792448 22904298
BRD4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32482868
H4C6 BRD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12489984 6546635
BRD7 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12489984 6546635
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
KLF8 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21518760 12820964
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7734951
E2F1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12629508
EGFR E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16299810
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
TBP EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9699517 8152794
ZMYND8 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27477906
EGFR H3C2 â—¼   COLOCALIZATION 2.0 0.8 intact 5216105 12577067
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
TADA3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707411 16713569
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
E2F2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11564866 18319725
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
H3C2 SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7903691 20389281
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
TP53BP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16945145
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CSNK2B TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11997511
RUNX3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24042352 22231444
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
HNF4A TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805548
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
H4C6 BRD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20709061 7989531
BRD4 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32416067 20676058 24945803 30428346
BRD4 BRD2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31753913 31239290 30554943 32416067 21555454
EP300 CHD4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 26546801 30110629 32699137 15189737
BRD3 BRD4 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BRD7 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20215511 35140242
MYC CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX3 NSD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20936779
ERG EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 28536097
EP300 KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
MYC RBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC PESC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
ANDR CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
MK BRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E41L5 BRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ANDR BRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24759320 28805820
PESC BRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BRD2 RPA34 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31753913
BRD2 MK67I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31753913
ANDR BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24759320 28805820
MK67I BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 30554943
CAMKV BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK E41L5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK67I PESC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26186194
PI42A E41L5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CBFB ERG â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
BRD2 BRD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CHD4 HIST2H4A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 HIST1H4A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
F90A1 BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
MYC BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29172540 30415952 32416067
PI42A BRD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913 31239290
BRD4 CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31239290 30554943 34079125 32416067
BRD3 CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 30554943 31753913
BRD2 CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 30554943 31753913
ESR1 E41L5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
DEN2D BRD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
F90A1 BRD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
PI42A BRD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913
BRD2 NSD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 26496610 31753913
BRD2 CSK2B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 30554943 26496610 31753913
BRD2 PWP2B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 26496610 31753913
F90A1 BRD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
PI42A BRD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913
DEN2D E41L5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HIST1H4I TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4E TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST2H4B TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4J TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST2H4A TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4B TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4D TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4H TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4A TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4K TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST1H4L TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST4H4 TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SNAI1 EP300 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28296173 25314079 32494626
NSD3 MYC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31638140 28628118 28205554
ESR1 HDAC4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19893013 16051668
HDAC4 RUNX3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24229708 15138260
ANDR ERG â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22722839 20478527
CSK22 PI42A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 23455922
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BRD2 HIST1H4J â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4J HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4H â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4H HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4B HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H4B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST2H4B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST2H2BE HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4D â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4D HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4K â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4K HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4L â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4L HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4I â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4I HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BRD2 HIST1H4E â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4E HIST2H2BE â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4F HIST2H4B â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAMKV BRD4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
H4 BRD7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12489984 27248496
CBX3 H4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30804502 27248496 24981860 21888893 14578449
BRD2 E2F1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10965846 17111193
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
SPOP BRD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29996942 31776466 28805820 28805822
CAMKV BRD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
CSK22 MK67I â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 23455922 27705803
BRD4 HIST1H4F â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
AR SPOP â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HIST1H4C HIST2H2BE â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
BRD4 SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28805820 34133717 34588438 28805822 31559706
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
EP300 HIST2H2BE â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
EP300 RUNX3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24229708 15138260
EP300 H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11163245 16096645 30804502 16109717 25728767 11884585 15951563 15611041 11830591 28465257 16415179 11689053 15308690 28844863 26625199 15136563 17982102 18397880 12499368 23587423 20368990 11689448 12237408 11983172 16717280 14752096 22100137 14612423 8945521 16287840 18418072 30902546 15834423 23934153 14585496 11691934 10607594 16332960
MYC TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15723054 8755740
NSD3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25640309 31527615
ANDR SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24508459 30244836 19762545 33158056 25274033
CBX3 HIST1H4F â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
BRD4 EP300 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4J â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4H â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4B â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4C â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST4H4 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST2H4B â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4D â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4K â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4L â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4I â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CHD4 HIST1H4E â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
MYC TOP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 30415952 29467282
H4C6 TP53BP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 16415788 5218238
TP53BP1 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 16415788 5218238
BRD2 E2F2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12145330 10965846
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
TADA3 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12034840 31527615 18089809 20413580
ANDR HDAC4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12943985 21242980
CSK22 BRD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26496610 31753913 32707033 23455922 30554943
BRD3 SPOP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBFB RUNX3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BRD4 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33640491 24759320 28805820
BRD4 BRD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31753913 26344197 30554943 32416067 21555454
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
MYC CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
SPOP BRD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28805821 31026449 28805822 28805820
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
MYC BRD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19111069
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ANDR CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15558026 16713569 11328859 16461912 10344732
CCND1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16061635 9039267 11073968
JARID2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21447557 19010785 12852854
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CSNK2A1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19923321
AKT1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18332867 28708672 16210317 11156376 11404460
ESR1 ZMYND8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26153859 18414489
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR SF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9801462 11518799 17520059
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
HIST1H4F HIST2H2BE â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CHD4 HIST1H4F â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
E2F2 RB1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CSNK2A2 CSNK2B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
EP300 HIST1H4F â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
BRD3 BRD2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 30554943 31753913
BRD2 HIST1H4C â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CCND1 RB1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
HIST1H4F TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
BRD4 H4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19766566 12840145 30804502 27248496 24525235 18500820 29176719 24361270 30554943 32416067
RB1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5219804 17380128
BRD2 H4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19766566 30804502 14731392 20709061 27248496 31753913 17148447
HIST1H4C TP53BP1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
BRD2 HIST1H4F â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CSK22 CSK2B â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 10799509 21988832 10094392 9571630 23555304 23455922 30279146 32296183 9188720 26496610 10561590 14667819 21486957 32707033 22939629 16713569 7768894 19011756 27705803 22863883 33961781 24981860
H4C6 BRD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27991587 24361270 12840145 18500820 24525235 19766566
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
RB1 CCND1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
KLF8 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 9190208 7575488 10385618 9736735 8490963 26225123 19237565 7736585 19075565 18590585 27507850 26121043 20068082 9425340 18786381 17660363 10778858 9380698 27430527
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
E2F1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   PROTEIN_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11533237 16081466 16738312 16188218 15618023 14681231 16230367 15985428 8264596 18583990 16601104 14627987 15016799 11268000 10490838 11818069
RB1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 17145710 23472054 12502741 22078878 8896460 12397079 9315635 20839231 16249186 11839806 8255752 11713253 20871633 15837424 8346196 19249677 16360038 8626527 12096339 15485814 16374512 18391203 9125176 16766265 9468140 8816798 12598654 10393912 9400991 9632788 12947005 19477924 15485920 17380128 10523633 10869426 7828850 18216119 8657117 12963846 25257171 17488475 28074012 15670817 11583618 7739537 10499802 8413249 11090181 8230483 22768064 29521627 10207050 9553123 7958924 11420730 23001041 16496386 9501179 19058874 1388726 9422723
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
KLF8 SNAI1 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 16617148 16831886 17563753 17671186 18832382 20731704 21317430 22406545
TADA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12034840 20413580 18089809 16713569
H4C6 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23760478 25579814 23377543 25651062 17190600 27153538 18296440 22373579 19218832 16415788
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
CSNK2A1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 29732088 17374729 21506126 11689703 10671551 12149249 15818404 10747897 10837139 20976471 19662498 21285348 11035045 11707428 21735093 17444818 20558317 11972058 16707567
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
H4C6 BRD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14731392 20709061 12776177 17148447 19766566
RB1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16360038 17380128 12502741 8657117 17488475 8246996 16189514 22569856 7739537 8832394