Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EZH2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23624935 21406404
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
FOXA1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16331276
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
SMAD3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768112 15735739
PIAS4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21113239
HDAC3 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
NCOA1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21163886 22542550
NCOA2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21505052 22581837
NR0B2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18537191 12571228
STAT3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11279133
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
CCND1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11279133
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
FOXO1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20082134 18444242
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
FOXO1 NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
FOXO1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18444242
TAF1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17085686 9285713
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
KAT5 SART3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22132941 23088399
KDM1A EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
HIF1A KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
SUMO1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
SUMO1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393906 11384992
SMAD3 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NCOA6 KDM6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
NCOA6 DPY30 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
SUMO1 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
PIAS4 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SIN3A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
HDAC4 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12032081 18691969
FLNA SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
AKT1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15461588 17570479
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD4 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
NR0B2 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
NR0B2 HDAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
HDAC3 BAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19595997 7216159
BCOR HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10898795
NCOR1 BAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19595997 7216159
NCOA3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 16860316
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
JUN CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18196534 17922191
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCOA2 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 10454563
ETV5 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15138262 17390339
SP1 FHL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16624878 0602109103
SP1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16516150 15818598
SP1 HDAC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16280357
SP1 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11574690
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
SMAD1 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
BAG1 NCOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19595997 7216159
NR2C1 NR2C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12615366 17645519
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CHD4 EZH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HDAC3 KDM1A â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
BRCA1 SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19768112 15735739
BRD4 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32416067 20676058 24945803 30428346
BRD4 BRD2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31753913 31239290 30554943 32416067 21555454
CSK21 CDC37 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 12930845 16335536 15082798
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 CHD4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 26546801 30110629 32699137 15189737
ANDR KAT2B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10779504 11328859
CSK21 KDM1A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 24486797 25999347
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
PIAS4 UBC9 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 22661230 12727872 20696768 21988832
CSK21 DAXX â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 33961781 21474068
CBP SRC â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16860316 15615775 16713569 22364282
GSK3B SMAD1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 18045539
PA2G4 BRE1A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19037095 19946338
GSK3B CCNE1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 14536078 8861947
SMCA4 CBP â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19448667 9584200 9443979
UBE3A RING2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20351251 26216987 30040487 33542309
BRD3 BRD4 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BRCA1 ASH2L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
BRCA1 KDM1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
JUN BRD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31239290 25609649
DAXX CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
ANDR CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
CBX5 RB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11484059 15485920
CBX5 TIF1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10562550 21531907
EGFR FKBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR FHL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29321665 15657067
ERG EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 28536097
ANDR FKBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20661446 21730179
FKBP4 TEBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11413142 25036637
SP1 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16050810 15647279
SMAD3 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 15994459
KAT2B NCOA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 9445475 9346901 9267036
KAT5 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25865756 21045206 32440780 23775119
KDM1A HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16140033
MDM2 G3P â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24583282 17373842
HDAC3 RCOR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23752268 33961781
RNF4 DAXX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 29695423
UBP7 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22875967 24654937
SUMO1 SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17036045 24654937
SUMO1 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
BRD3 TAF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
MLL2 DPY30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17178841 24981860
ANDR DPY30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 32814769
JUN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17056544 25609649
EZH2 HDAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23079660 21685935
ANDR SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 16469706
SIN3B SIN3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
JUN GBLP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 21860413
DAXX ITF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19563778 20211142
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
CTNB1 CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19244345 18356165
CHIP PA2G4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27464702 24651434
NCOA1 NCOA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
GSK3B GELS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30711629 30824926
NCOA3 NCOA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18267973 11971985
ANDR CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
ANDR BRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24759320 28805820
ANDR CPSF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 32814769
ANDR SIN3B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 16469706
ANDR BRD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24759320 28805820
BRD3 CHD8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
ANDR MED24 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 19762545
HSP71 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20048054 1540595
RING2 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 24457600
HS90B ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32206096 21730179
ANDR ACL6A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
ANDR SMRD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
ANDR I2BP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
ANDR CSK21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 32814769
ANDR ZBT16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19762545 23798432
ANDR OGT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 34585037
ANDR PA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 23161582
CBP PAX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 32238831
CSK21 MLL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
NR2C2 SMRC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30463901 26496610
ACL6A ARI1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 24981860
ACL6A ARI1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 24981860
SMRC2 UBE3A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SMRD2 ARI1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
HS90A G3P â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 16263121
HS90A YES â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 31980649
YES HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 31980649
BRD2 BRD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
SMCA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27591253 15034933
BRD4 MED1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19766566 33567268 31239290 20098423 30554943 32416067
BRD4 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 32416067 16109376
ACK1 CDC37 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28739485 31980649 33961781
CCNE1 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HS90A CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939624 28514442 26186194 33961781
PELP1 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33742100 11481323
CTNB1 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15572674 33742100 15806138 26123998 33190089 11050151 32603375 30986748 15060161 30836930 26657156 12408825
KAT5 ZN363 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18263878 14701804
KAT5 STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12551922 16713569
KDM1A EZH2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31130994 23455924
KDM1A NR2C2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30463901 21670149 23455924
TS101 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17060450 11172000
PA1 NCOA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23508102 24981860 17500065
NCOA6 MLL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17178841 17021013 12482968 24981860 32350066
PIAS4 SMAD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 15231748 12904571
ANDR RCOR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
UBC9 RNF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29180619 19549727 32296183 20936779
HS90A STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12559950 16189514
UBC9 RAN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
PA1 DPY30 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23508102 24981860 17500065
KDM6A DPY30 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17178841 24981860 29785026
SMAD4 JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10220381 25609649
SMCA4 HDAC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19081374 20596014 12192000
HDAC1 CTNB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16204248 19166851 31130994 10958684 27684187 17412698
EZH2 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27634302 27705803
HDAC4 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17011572 10220385 17210713
BCOR HDAC4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 10898795
HDAC4 TBL1R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31040226 23752268 27684187
EZH2 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28486105 28068325 24981860 26344197
CHD4 CSK21 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 22113938
CHD4 SMRC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11003653 16217013 28977666 32744500 22939629
SMCA4 CCNE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11085541 9891079
ANDR GSE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
ANDR BCOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 31925334 33640491
RB GBLP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 12761493
BRE1B ANDR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33640491 34585037 22155569
TEBP ANDR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20048054 22899854
BRE1A ANDR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33640491 34585037 22155569
ANDR SNF5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
ANDR ARI1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
ANDR ARI1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
ANDR TBL1R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33640491 32814769 16469706 34585037
ANDR TLE3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
ANDR REQU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
ANDR SMRD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 19762545 33640491
ANDR SMRC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 33640491 34585037
SMCA4 SMCA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9128241 18042045 31753913 24981860 22939629 14559996
SMCA2 SMRD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31753913 24981860 22939629 26344197 14559996
REQU ACL6A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28533407 33961781 24981860 26186194 29374058
ACK1 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28739485 31980649 22939624 23729439 16288044
ACK1 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939624 28739485 31980649
ARI1B ARI1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15170388 24981860 29374058 22939629 26344197
CTNB1 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 27684187 15492215
CTNB1 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 27684187 32814053
AKT1 BRCA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT5 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NCOA1 NCOA2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PRKDC BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10608806 25223785
SNF5 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10943845 27591253
BRCA1 NCOA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14578343 16860316
BRCA1 SMRC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10943845 26831064
BRCA1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25531315 23624935
BRCA1 SMRC2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10943845 26831064
BRCA1 UBC9 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19287951 20016594
CBX5 SMCA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20011120 20562864
EP300 RAN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12649209 33742100
GAK ANDR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12864730 16161052
RB KAT2B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19249677 15044952
KDM1A SMRC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22939629 26344197 28420882
ITF2 PIAS4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15831457 12727872 20211142
SUMO1 PIAS4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20016603 15831457 16524884
RAD9A HDAC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10846170 16189514
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
RANB9 RAN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11470507 9817760
ANDR FLNA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12682292 16713569 11043577
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
SMAD3 CTNB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12000714 22241478 20571128 21965288 27684187
BCOR HDAC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 23658227 10898795
HDAC3 NR0B2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15835920 17895379
HDAC3 RB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10490602 16189514 10958676 12479814
SP1 RB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11158299 10850422 7732011 11896613
GSK3B HS90A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22824801 19682504 23455922 30824926
ANDR ERG â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22722839 20478527
MAGAB NCOA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19828458 20448036
ANDR DCAF6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28212551 15784617
CHD8 ANDR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33640491 20308527
RB ZBT16 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18504436 15949438
ACK1 ANDR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17494760 31819114
ANDR UBP7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33640491 26175158 34585037
UBC9 ITF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12727872 23395904 23772552
HIF1A STAT3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIF1A KAT2B â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HDAC1 NR0B2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC3 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CSK21 BRCA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10403822 16713569
BRCA1 PO2F1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11777930 20215511 27465491 18000219
CCND1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11279133 15659654
GSK3B CDC37 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23455922 29568061 33961781
ACK1 EGFR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24413169 20086093 17182860 18435854 18271526 19815557 8497321 8647288 20359967 15657067
EGFR YES â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23866081 22973453 24797263 15657067
ANDR EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18487222 16713569 27903893 24480624 10779504 32668201 28549433 23172223 34585037 23518348
ITF2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17410209 17050667
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
RB HMGB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11748221 16189514
KAT2B NCOA4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9892017 16713569
MDM2 HS90A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24147044 24583282 15001357 15001356 20540933
NCOA6 NCOA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10567404 12482968 21292004
SP1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17471507 24396070 21184768 16931573
HDAC1 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15653507 22750444 15870198 22116549
MK01 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12763138 15979846 10521505 9872331 9343414 11350938 12576423 10446219 14551213
STAT3 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15735682 18985005 23604114 23991099
TAF1 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11316804 16713569
DPY30 MLL1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31685992 24981860 17500065 31485071
SMAD3 CHIP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14701756 32737199
HDAC1 NR0B2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15835920 17895379 21566081 21262773
HDAC3 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
SIN3A CSK21 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 17827154 22939629 26344197
NCOR2 NCOR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16033423 10944117 11013263
UBC9 JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10788439 16713569 11877416 8733011
HIF1A JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
JUN HS90A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20195357 25609649 20936779
HS90B SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 28215707 31980649
AKT1 CBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19995607 23434580
PIAS1 ANDR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31752909 11877418 12177000 25552417 11117529
CBP SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10673036 11239394 33323411
SPOP BRD2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29996942 31776466 28805820 28805822
ANDR EZH2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24457600 27728805 30628724
NR0B1 ANDR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12771131 11875111 16713569
TS101 ANDR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10508170 29859188 16713569 23146908
ANDR TCF20 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28611094 33640491 21935435
ANDR UBE3A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9891052 27903893 16254014
ANDR T2FB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9238003 16713569
ANDR MPIP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12569365 16713569
ANDR ADT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16120611 12039962 16713569
ANDR TF2H1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11266437 10734072 16713569
ITF2 CALM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10757985 16189514
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ANDR ASH2L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33640491 22722839
BRCA1 FLNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22990118 20305393 16713569 26831064
BRD4 SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28805820 34133717 34588438 28805822 31559706
KAT2B CCND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11328859 10318892
CDC37 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 11085988
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
SMAD4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 25514493 18215124 9843571 14612423 10887155 22033265
EP300 FOXO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15890677 24419059 25609649 18786403 11896584
EP300 NCOA2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10490106 9920895 15731352 20448036
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
KAT2B HIF1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22908229 21148070 20620956 16543236
PIAS4 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14981544 11439351 16713569
PRKDC ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26175416 15640154
ANDR RAD9A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14966297 16713569
RNF4 SP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34550526 10617653 21983342 26511642
CBP STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15653507 15649887 11239394
SVIL FLNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20309963 26496610
MK01 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19914168 10197981 16156666 18729074
CASP8 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17170703 16713569
ANDR CALR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8107809 16713569
CSK21 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21075308 31980649
PELP1 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14963108 15466214 12415108
AKT1 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21767636 18292230
CBP NCOA2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15657427 11971985 9430642 9192892 15987788
BAG1 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25036637 20675402 26330542 11676916 15538384 16207813
ANDR CCNE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 10953010
MK01 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10318905 9725910
NR2C1 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 12949936
ANDR SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24508459 30244836 19762545 33158056 25274033
CBP SNF5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9584200 9710619
HS90B HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 16263121
CSK21 RING2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21282530 27705803 25519132 22325352 33961781 32707033 24457600
ACL6A SMRD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24981860 11780067 26344197
ACL6A SMRD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11780067 33961781 20305087 24981860 26344197
BRD4 EP300 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
PA1 ASH2L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23508102 24981860 17500065
ASH2L CHD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20085832 24705355
SP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14710355 16713569 12706836 10720440 17766039
CBX5 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32744500 27705803 24981860 15882967 28977666
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
CDK7 HS90B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17643375 22939624 33961781 26186194
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
RB EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16878158 11433299 17620057 31753913
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
EP300 NCOA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 10973497 20368990 15688032 14722092 12208951 11113179
ANDR HMGB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11748221 9671457 16713569
ANDR KDM1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20228790 27085459 33640491 28611094 34585037
KDM1A GSE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 21258344 12493763 16079794
SUMO1 MDM2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21316347 12917636 22411991 18583933 15876874 12393906 12297306 20972456 11384992 15876864 17000718
KDM6A NCOA6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17178841 17761849 19433796 24981860 19047629 29785026
NCOA6 DPY30 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19047629 24981860 17500065
NCOA6 PRKDC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10823961 12519782
PIAS1 SUMO1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27032383 24654937 19217413 15561718 22578841 16524884 11583632 14609633 18806873
ANDR TAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20181722 33640491
ANDR KDM6A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33640491 22722839 34585037
KDM6A PA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17178841 17500065 23508102 33961781 24981860
KDM6A MLL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17178841 17761849 24491801 24981860 32350066 29785026
HDAC1 GSE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 26496610 21258344 33961781
ZBT16 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24821727 15467736
NR2C2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12943985 21670149
HDAC3 HIF1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17273746 11641274
SNF5 SIN3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11238380 14559996 12453419
MLL2 PA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17178841 17500065 23508102 33961781 24981860
ANDR MLL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28611094 33640491 22722839 32814769
CTNB1 HIF1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22865883 23246962 24650032 17220880 23671189
HIF1A ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22865883 17426252
NCOA1 NCOA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18267973 9774463 11971985 9751728
GSK3B HS90B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30711629 23455922 30824926
GSK3B G3P â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21900206 30711629 30824926
UBC9 PIAS2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 16189514 25416956 16713569 11867732 21988832 19549727 16148010 12177000 25409927 20936779 14609633
BAG1 RB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 12845674
ITF2 GSE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 25609649
ARIP4 ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16212558 10961928 19692572
SVIL ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 11792840
PAX6 ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19790232 21935435
SRY ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11585838 16713569
RT29 ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10903152 16713569
RNF6 ANDR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19345326 28324045
ANDR SMRC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28611094 14966121 33640491 34585037
ANDR CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27835608 16725394 21157430 30446660 27903893 15107424 29249800 19706771 20661446
ANDR YES â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32814769 24728074
ANDR JHD2C â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28611094 33640491 17353003
ANDR SMCA2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18487222 19762545 33640491 28611094 34585037
SMCA2 SMRD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18042045 31753913 33961781 20305087 26186194 24981860 20460684 22939629 26344197 14559996
SMCA4 SMRD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30962207 12368262 24981860 31043422 29374058 22939629 26344197 14559996
AES TLE3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 33961781 24981860
REQU SMRC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20400511 28533407 22334708 33961781 24981860 26186194 29374058 20460684 26344197
REQU ARI1B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 28533407 33961781 24981860 26186194 26344197
ARI1B SMRC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21118156 20086098 33961781 20305087 24981860 22939629 26344197
ARI1B SMRD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21118156 33961781 20305087 26186194 24981860 22939629 26344197
REQU SMRD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 28533407 33961781 24981860 26186194 26344197
REQU ARI1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20400511 33961781 24981860 26186194 26344197
REQU SMRC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20400511 28533407 33961781 20305087 26186194 24981860 26344197
SMRD1 SMRD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20305087 26186194 24981860 22939629 26344197
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
DAXX SPOP â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
NCOA6 ASH2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17178841 19433796 17925232 12482968 17500065 23870121 23508102 33961781 24981860 34079125 19047629
OGT1 ASH2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31076518 27705803 23353889 23508102 34079125
BRCA1 NCOA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14578343 11085509 16860316
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
CDC37 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22504172 12176997 31980649 24869908
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
EP300 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9267036 25314079 10899165 31753913 30110629 15598887 17970752
FKBP4 HS90B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21730179 25036637 21170051
ACL6A KAT5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11839798 15647280 27153538 10966108 14966270 29028833
HDAC3 KDM1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23752268 21258344 21670149
NR0B2 MDM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33889569 22575647 22197810
NCOA6 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33640491 14645241
PIAS4 SMAD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12815042 12740389 12904571
PIAS4 SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12815042 12904571
AKT1 PRKDC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15678105 15262962
PRKDC ERG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24591637 21575865
TCF20 RNF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10849425 29180619
JUN STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
ZBT16 SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18348865 14527952 17498654
CBP SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28630323 23395904 27129204
SP1 SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18239466 18572193
ANDR COX5B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 11719263
RAN ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 32814769 10400640
HS90B FLNA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 26496610 16263121
UBC9 SMAD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29892012 16189514 16713569 15231748 21988832 15637079 12621041
SMAD4 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12226080 16713569
GSK3B SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21310903 18172167
SMAD3 UBP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34580281 18729074 21988832
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
SMCA2 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11238380 26496610 12453419
CBP DAXX â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16287980 32545337 11799127
HIF1A GBLP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25959252 25204544 19251694 27320910 23722539 24648344 17244529 17875644
SP1 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23369005 9535906 10809237 17984071 15661808
SMAD1 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17183365 23734213
ANDR HDAC4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12943985 21242980
HDAC4 NR2C1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12943985 11463856
ANDR GSK3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15361837 15178691
CHD4 SMCA4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11003653 16217013 32744500 14530259 28977666
UBP7 EZH2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32064169 31130994 33849069 32453339 27634302 20800574 31866294
ETV5 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8798622 11509567
SART3 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 15031286
BRD3 SPOP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
UBC9 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8798622 19692572 10383460
PRP6 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12039962 16713569
RANB9 ANDR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16595702 12361945 16713569
ANDR T2FA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9238003 20541699 16713569
ANDR MLL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33640491 22722839
ANDR ITF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12799378 16713569
CBP CSK21 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9685505 16051665
SMCA2 REQU â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31753913 22334708 33961781 24981860 26186194 20460684 26344197
ACL6A SMRC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11780067 24981860 24421395 21699904 22939629 26344197
REQU SNF5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31759698 30108113 28533407 33961781 24981860 26186194 20460684 26344197
ACL6A SMRC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 11780067 33961781 20305087 24981860 22939629 26344197
NR2C1 NR2C2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30463901 12093744 21670149 9737983
REQU SMRD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28533407 33961781 20305087 26186194 24981860 20460684 26344197
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED1 MED24 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
KDM6A ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17178841 17761849 31076518 23508102 33961781 20305087 24981860 34079125 29785026 17825402
MLL2 ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17178841 31076518 30107592 17925232 12482968 24491801 27563068 23508102 33961781 24981860 16603732 34079125 32350066 26886794 30604749
CBP BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10655477 11782371 16713569 16417649 9926942 12700228 16860316 9443979
HDAC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21102443 10220405 16713569
CCND1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17334399 16713569 9244350
ANDR BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11085509 16713569 11016951
MED1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15208681 16713569
BRCA1 SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
BRD4 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33640491 24759320 28805820
BRD4 BRD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31753913 26344197 30554943 32416067 21555454
HDAC3 CCND1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15713663 12048199 16461912 20484017 15558026
EGFR CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 12471035 24189400 23956138
YES CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 25036637 31980649
CDC37 CDK7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8666233 33961781 29568061 26186194
ANDR CDK7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10734072 21157430
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
HS90A FKBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 25036637 22678819 22504172 21360678 22863883 10642522 33961781 21170051 20661446 20188096 19875381
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
KAT2B NCOA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9445475 9296499 9223281
KAT5 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10364196 11994312 11591700 16713569
HDAC1 KDM1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16079794 19703393 21258344 34050636 11102443 27183383 16140033 21937684 12032298 26496610 22143567 19497860 11171972 17634443 12493763 20856864 20585571 31130994 21670149 26344197 23752268 32882276 17687328 33961781 24981860 28667074
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
TAF1 MDM2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9388200 17237821 16713569
NCOA1 STAT3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17471507 11773079 16713569
SP1 SMAD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10878024 18215124 21297662 16714330 11114293 22033265
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
SP1 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11432852 10878024 12228247 22227581 16714330 11114293
HDAC1 NCOR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11739383 16481466 11013263
HDAC1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15640443 11994312 16713569 15835920 26468294 34585037
ANDR HDAC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12943985 33640491 16469706
TBL1R HDAC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 28152507 16469706 11931768 18202150 21258344
NCOR2 SIN3A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10944117 10640275 11013263
SIN3A SMRC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11238380 11784859 12453419
SIN3A OGT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16505006 12150998
SP1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25879517 10506225 16713569 33572115 16478997 17215518
NCOA1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10847592 10567404 16713569 9642216
RB JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10026157 9545246
JUN MK01 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10419510 29225075 1922387 25609649 11431474
DAXX UBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23536002 32587091 18566590 16845383 33961781 24981860 23348568 32545337
DAXX SPOP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31911863 21988832 30244836 21573799 16524876 15240113 28805822
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
HIF1A HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20668552 19802386 18538669 26517842
HS90A SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 1310678 16844778 22315411 28537252 32707033
SRC CAV1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8910575 8632005 8621645 29720121
CAV1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11278309 16713569
SP1 SMCA4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15317818 12192045 20969766 11018012
HS90B AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10995457 20650008 31980649
PIAS1 UBC9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11867732 16148010 12177000 19692572 25557546 30217970 12356736 20936779 19965618 15561718 22661230 11583632 14609633
SMAD1 CHIP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14701756 23344957 21454478
UBC9 HDAC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18691969 16166628 11451954 23417673 17491593
ZBT16 HDAC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19648967 15467736 11929873
HDAC4 NCOR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31040226 12205093 10640275 11804585 27684187
PIAS2 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11117529 16713569 12177000 9920921
NCOA3 SPOP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29996942 21577200 34144977 28805822 23559371
PELP1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15466214 16713569 12415108
NR0B2 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11735420 17482455 16713569
UBP7 BCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26687479 33722704 16713569 26496610
SPOP BRD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28805821 31026449 28805822 28805820
CTNB1 CHD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22083958 11744694 18378692
SMCA4 RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12434308 9128241 19081374 23438604 15485920 10778858 7923370 17666433
ANDR RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16964284 16713569 9813067 9675141
CALM ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32814769 14695896
TMF1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10428808 12165860
FHL2 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10654935 16713569
NSD1 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11266437 23975195 16713569 11509567
TIF1A ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19909775 16713569 9115274 33640491 34585037
ANDR SMCA4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18487222 19762545 33640491 28611094 14966121 34585037
ANDR G3P â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32814769 8872471 16713569
UBC9 CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28630323 22227369 28680062 23395904
CBP MLL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12205094 16799563 11259575 17707401
ACL6A SMCA2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11839798 12437990 31753913 8895581 24981860 20460684 22939629 26344197 14559996
SMCA4 REQU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 30962207 20460684 28533407 22334708 33961781 24981860 26186194 31043422 23540691 26344197
SMCA4 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 16675956
SMCA4 CTNB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19571879 11532957 29463646
ZBT16 FHL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12145280 16713569
SMRC2 SMRC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19650111 18809673 16230384 20305087 24421395 9584200 33961781 24981860 22939629 26344197
SMRC1 SMRD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 24981860 26344197
SNF5 ARI1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31759698 30108113 33961781 24981860 11734557 22939629 26344197
SNF5 ACL6A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11780067 31759698 30108113 8895581 33961781 24981860 26344197
BRE1B BRE1A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24441044 27569044 27557628 19410543 16307923 21329877 33961781 30649429 21362549 29507117 25533843 22155569
ARI1A SMRC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19650111 11780067 33961781 20305087 24981860 29374058 22939629 26344197
ARI1A SMRD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11780067 33961781 20305087 26186194 24981860 22939629 26344197
CHIP HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32600329 25036637 32401531 20618441 16293251 32041778
ARI1A SMRD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 24981860 26344197 30021884
KDM6A NCOA6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ASH2L NCOA6 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
ASH2L MLL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31544921 28182322 20305087 21285357 15960975 22665483 15199122 16892064 31685992 20064463 23870121 23508102 26886794 31076518 19556245 24235145 27563068 33961781 24981860 34079125
ASH2L DPY30 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 23995757 31076518 17500065 19556245 23508102 33961781 20305087 24981860 21516116 23414517 31485071 22231628 34079125 25456412
SMCA4 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15034933 16713569 23438604 10943845 26831064
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
JUN BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12080089 25609649 16713569
AKT1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21242970 10542266 20085797 19074868
RB BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11521194 10220405 16713569 10518542
BRCA1 FHL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14986435 25184681 14550570 21988832
EZH2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19079346 20574448
CBX5 SMCA4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12411497 20011120 15882967 20562864 19498464
ANDR CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15558026 16713569 11328859 16461912 10344732
RB CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15485920 9003781 8867812 9823309 8662825 9139732 11593423 10486249 11126356 12676926 15681588 21242975 31217276 10491434 9190208 8490963 8647086 8449399 21654808 9178893
TAF1 CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9926939 16713569 11126356
FOXO1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22266855 12391153
NCOA3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11358796 19095746 15808510
CDC37 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 33961781 31980649 11085988
CDK7 TF2H1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8692841 9852112 8521393 7533895 9130708 23602568 28977422 32707033 29568061 26340423
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
CHIP EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33775711 20029029 31980649 24658140 25402006 24722501 27475501
EGFR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32669362 20029029 31980649 16849543 12471035 23956138 16024644 24189400 24658140 12006493 25402006
EGFR CALM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 24658140 14960328 11853560 25402006 16799092 12359306 12153558
EGFR CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9535896 24189400 9233779 11950845
EGFR HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 23956138 24189400 24658140 22939624 25402006 15657067
EGFR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 23956138 20145033 21573184 25402006 15485908 15657067 14966128 9756944 18258752 15284024 24189400 24240702 25754235 24135280 15950906 24658140 12873986 20067773 10358079
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
EGFR HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 25241761 31980649 24189400 24658140 25402006 15657067
EGFR G3P â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 23956138 24658140 25402006 16799092
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
EP300 NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16923966 10655477 9267036 23065768 16227615 20368990 11823864 10490106 25728767 33589584 10866661 15145939
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
ANDR FOXO1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17202144 12482965 16713569
CBP FOXO1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10973497 24419059 16154098 25609649 15220471
KAT2B MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21209460 21060154 32404984 14769800 12068014 28286521
KAT2B CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8684459 11864601 9267036 9710619 9445475 9687573 9687513
NCOA1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12163591 10809234 10777539
KAT5 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18499675 11927554 18264029 19150978
MDM2 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11927554 16904321
RCOR1 KDM1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19703393 21258344 34050636 11102443 18806873 16140033 12032298 22143567 20389281 11171972 21300290 16885027 21602794 26226427 21142040 21670149 26344197 24217620 32882276 20164337 28667074 17687328 33961781 27173435 24981860 34079125 34031383 16956976 16079794
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
HIF1A MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12606552 10640274 25447306 15880652 19696166 25535359 17234751 15385570
RB MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25703327 16337594 33185004 20871633 21990374 11433299 16374512 10078201 16510145 15044952 15485814 7791904 9003773
MDM2 UBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28406480 16474402 26238070 16943424 28196907 29295817 22056774 34799561 26971997 24462112 18566590 29236775 16402859 20713061 31647545 20816748 16845383 17380154 26460617 27452404 17936559 15916963
TAF1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 10891494
GSK3B MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055726 18505846
TAF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9388200 17237821 16713569
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
NCOA6 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10847592 11158331 10567404 12482968
NCOA6 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11158331 10567404 10866662 12482968
ANDR NONO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17452459 12810069 16713569
RCOR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 17939992 19703393 12032298 26496610 17938259 21258344 33961781 15897453 19497860 12192000 11602581 11171972 17956988 18806873 11102443
SUMO1 RNF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29180619 32296183 24907272 15707587 23086935 24151981 24844634
SRC STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 21573184 15313931 11294897 8657134 18070987 10918587 12244095 19372587 12626508 8626374 14551213 16713569 8272872 11350938 9566874 12576423 11940572 15735682
ANDR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12804609 11322786 16713569 11751884
STAT3 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22583478 19049964 19010822
PIAS2 SUMO1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 11867732 21988832 24654937 16524884 19217413 16204249 14609633 17036045
TAF1 T2FA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7590250 9482861 9858607 15053879 8625415 9660973 10428810
TAF1 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 7724524 16713569 9858607 11126356 9242374
AKT1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 23397142
SMAD1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 17183365 16189514 32296183 31467278 12167862 14701756 12874272 28468752 15761153 24412244 10531362 15231748 11700304 11779505 26555259 9436979 21454478
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SP1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21421563
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
PIAS2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14514699
AKT1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 25241761
SMAD3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11707452 11280774 12226080 16713569
SMAD3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10903323 11306568 10220381 9732876 21829441
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
CHD4 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25247294 32744500 21258344 11102443 28977666 9885572 26496610 20585571 10220385 22075476 21670149 22939629 23752268 27616479 9790534 9804427 26949739 20693977 33961781 24981860 12920132 26344197
ZBT16 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19648967 24821727 16189514 9627120 15467736 16024608 26264872 29997244 32814053 9765306 11865059 23898169
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
HDAC1 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10490602 16189514 15003538 11909966 15485920 10888886 11158299 11896613 11583987 10228159 9988677 10778858 11839806 22615382 19081374 12466959 26264872 9491888 10615135 16766265 15044952 17827154 22366686 12473678 10499802 23752268 10891495 9468140 11684023 10958676 21900881 29997244 9724731 10779361 9468139
HDAC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15647279 20072153 19062177 11909966 17894944 21636851 18003922 12176973 11896613 15557281 10409740 11517158 15713621 12665570 15722551 17906119 16478997 18850004 16121030 16883603 12091390 15155736 18948152 18059533 16713569 20385359 15528196 16734381 12200149 12847090
HDAC1 SIN3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 11959842 20585571 10357820 15935060 10444591 26496610 33961781 11102443 24951594 26344197
BCOR HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 10898795
HDAC3 NCOR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12205093 21624135 10809664 24449765 16924111 10944117 21258344 11509652 26728228 15837933 12628926 11804585 22230954 14527417 16980585 23752268 29523594 12502735 10860984 11013263 16481466 17126328
HDAC3 NR2C1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12943985 14521922 21670149 19204783 11463856
HDAC3 HDAC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 10220385 10869435 11466315 11804585 17956988 27684187 18558095
SMCA4 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19081374 11238380 16800816 11784859 14559996
ZBT16 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24821727 9765306 9627120 11719366
SMCA2 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11238380 15314177 12453419 26344197 14559996
ZBT16 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9531570 24821727 16024608 16713569 9824158 11865059
HDAC4 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 16713569 10640275 10860984 11804585 17956988 27684187
TBL1R NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28152507 15601853 12628926 28588275 28348241 11931768 18202150 21258344 14527417
NCOR1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20974212 12089345 16713569 16914745 33640491 32814769 16469706 23518348 28611094 11971970 20812024 28549433 15256534 15598662 14593076
AKT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23940660
CBP JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 2138276 17296604 9786917 18443043 10327051 8028671 9659924 15994313 16055710
CSK21 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 1516134 9685505 12628923 25609649
ANDR JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 16713569 8798722
JUN NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15292277 12842887 19322021
UBC9 DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17081986 18691969 15087395 16713569 23395904 12150977 21474068 11112409
ANDR DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572661 27671201 32694250 15350595
HIF1A HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 17442277 15147973 20724477 16507982 26517842 18538669 17237281 14726529 9079689 14764593 23722539 20668552 21413014 24844779 25204544 15319539 24648344 17244529 19491109 33550096 16951198
ANDR SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24728074 15062576 11032808 15466214 15027889
SRC GBLP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 11964397 18596232 11279199 9584165
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
NCOA1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 17400812 17495236
SP1 PO2F1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19070619 16713569 8668525 9525610 10976766
SP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18632985 18850004
AKT1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18332867 28708672 16210317 11156376 11404460
AKT1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19713527 8524413 23824745 16009706 29464284 20856200 19995607 16123141 20682768 27563096 14645548 15688030 22337773 11035810 17428466 18505846 15470047 14701753 16282323
PA2G4 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9565586 15583694 12165860
PA2G4 RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 19946338 11268000
NCOA1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15256534 16713569 10731636 33640491 12612084 23975195 12163482 10567563 17353003
NCOA1 CBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15615775 16713569 11971985 12482968 12163591 9445475 11003650 8616895 9192892 14722092 16860316 11113179
GSK3B MED24 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MED1 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 9653119 33961781 24981860 22939629 20133760 26344197
MED1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12218053 33640491 16713569
NCOA3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21047772 16713569 11747336 16951154 15563469 33640491 14966121 10965917 32668201
ZBT16 NCOR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24821727 16024608 9824158 9256429 9765306 11865059 14982881
ANDR NCOR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22508987 15062576 34585037 17356171 28611094 20812024 11923464 12441355 14593076
NCOR2 PO2F1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27465491 11134019 19617623
BAG1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14517289 11278763 9565586 16713569
TGFI1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 11856738 11155740 10075738 11779876
RNF14 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17110431 11673464 16713569 17082327 15604093 12612084 19345326 10085091 24422631 11779876
ZN363 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 27903893 16914734 12200228 17721809
FOXA1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 33640491 25552417 23260764 12750453 22722839 34585037
AES ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33640491 11416139 16713569
NR2C2 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33640491 16713569 10611280
NCOA4 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10318905 16713569 15563469 10347167 9636157 9892017 15604093 12612084 8643607 11818501 12068007 10517667 10969079 17011702 11404460 11779876
PAK6 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23132866 16713569 11773441 11278661
CBP ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12810069 16713569 9822653 20541699 33640491 9482849 15691881 34585037
ANDR CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22865883 21885566 16713569 12799378 11792709 15060161 11916967 12944908 22187462 21741601 12588987 10987273 15256534 14593076
ANDR MAGAB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21730049 18212060 24722188 19828458 15684378 23172223
ANDR UXT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23961993 11854421 16713569 21730289
ANDR GBLP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12958311 32814769 16713569
ANDR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 16713569 21157430 32206096 27903893 17974989 1540595 26342197 26196320 25500540 19706771 19805354 17353003 1525041
ANDR GELS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12941811 16713569 19574450 15604093
SMCA2 SMRC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11238380 31753913 8895581 16452305 16230384 24421395 16940996 24981860 20460684 22939629 12453419 26344197 14559996
SMCA2 SMRC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16940996 21653829 31753913 8895581 20305087 33961781 24981860 12453419 20460684 22939629 26344197 14559996
ACL6A SMCA4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30962207 9845365 11780067 22939629 29374058 8895581 24981860 31043422 21699904 20460684 15985610 26344197 14559996
SMRD1 SMCA4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 30962207 18042045 12917342 22939629 29374058 33961781 20305087 26186194 31043422 24981860 18303029 20460684 15985610 26344197 14559996
SMCA4 SMRC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12917342 12368262 9891079 10078207 18809673 21520050 16217013 11726552 18303029 18086889 20460684 16287714 30962207 9845365 11238380 8895581 16230384 23540691 15985610 22939629 26344197 14559996 24434208 31759698 24981860 16452305 31043422 28420882 29374058 9584200
HS90A HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27353360 24949977 11413142 12093808 16263121 21360678 12853476 19875381
HSP71 CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 32401531 10330192 12150907 16275660 33961781 20618441 28042827 27787517 26010904 22939629 23904609 23271055 33957083
CSK21 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 2492519 22113938 22824801 7794926 19740745 16335536
TEBP HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10543959 25036637 21183720 21988832 17010336 33961781 18285346
TEBP HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 10811660 21988832 18172314 10642522 12077419 18285346 11447118 8114727 26151834 23022381 25036637 16403413 14987994 22729780 22504172 22315411 14761955 26804907 11413142 9817749 20159553 20039095 22806877 19875381 27353360 15916966 11812147 19740745 16289154 33961781 19996313 20661446 16565516
FHL2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12466281 16713569 27684187
T2FB T2FA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8441635 16189514 31467278 7854423 30415952 24981860 11183778 7827505 8662660 26344197
SNF5 ARI1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19650111 31759698 30108113 8895581 33961781 24981860 29374058 11734557 22939629 26344197
ITF2 CTNB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17983804 23449499 11713476 12944908 16230076 21743491 17318191 18281465 25402006 16724116 23671189 30691485 22155184 33643786 29463646 28829046 31286874 17909039 15060161 12727872 15331612 19114997 24532795 17412698 17050667 22080605 29361949 16630820 17072306 17220880 15665104 24876153 15525529 21103407 24798214 12657632 20126258 26123998 17875931 17962194 11713475 33754069 29374067 16007074
HS90A CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23344957 23256568 17317785 21454478 18818696 20661446 12574167 11146632 22824801 20618441 30911017 19913553 15538384 16307917 32600329 26330542 16275660 20704274 21325980 15001357 16293251 33571422 17324930 23904609 23999428 19875381 27353360 18784277 19196961 20146531 21360678 18292230 16207813
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RNF4 SUMO1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HDAC4 NCOR1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ASH2L KDM6A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HDAC3 HDAC4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
AES HMGB1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 11748221 16713569
HIF1A HDAC4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 15280364 19071119 21148070 30867818 16951198
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
SUMO1 JUN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10788439 15469925 11867732
ANDR PO2F1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10480874 16713569 11096094
RING2 UBP7 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 20601937 26496610 22325352 20800574 24457600 25605328
HS90B G3P â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 26344197 16263121
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
HDAC1 RCOR1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CBP SMAD3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 19589780 27566588 10497242 18003620 17283070 15467747 33323411 15849193 15990875 15750622
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
BRD3 BRD2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 30554943 31753913
ARI1B SMRC1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 21118156 20086098 16230384 15170388 24421395 24981860 22939629 26344197
ARI1A SMRC1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 19650111 31759698 15170388 24421395 16230384 9584200 24981860 22939629 26344197
SMRC2 SMRD2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 20305087 24981860 22939629 26344197
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
AKT1 FOXO1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10358075 25241761 10358014 16076959 31844113 18786403
SUMO1 HIF1A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 20026589 15876874 24434214 20661221 15465032 17938407
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
NCOR2 HDAC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24449765
NCOR1 SIN3A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17210713 11430826 16713569
SRC CTNB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 23246962 11279024 22056988
AKT1 HS90A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32707033 16189514 21767636 12176997 31980649 25714412 15843522 29311840 22504172 16027165 29139175 12586360 19356729 10995457
HDAC4 NCOR2 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
BCOR RING2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16943429 26687479 27505670 33468080 26496610 27705803 22325352 24981860 24457600
SNF5 SMCA2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18042045 31759698 11238380 30108113 31753913 8895581 33961781 24981860 12453419 9744861 22939629 26344197 14559996
SMRD2 SNF5 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 31759698 30108113 33961781 24981860 22939629 26344197
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
AKT1 MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32450252 25241761 18332867 12145204 19166854 15527798 20856200 11715018 23397142 11504915 11923280 21930127
ANDR MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15640443 32801300 33332287 21157430 18332867 12145204 29755129 28708672 27903893 17974989 29402932 26973243 26196320 23132866 26411689 28151478
RNF4 ANDR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11719514 9710597 10617653 16713569
CSK21 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 23752268 22113938 11327722 11602581 17827154
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
NCOA3 CBP â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9267036 16713569 11971985 17043108 16227615 9346901 15383283 11823864 9445475 21632823 33589584 9192892 8616895 26267537 11076796 21914189
CBP CTNB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 26123998 16476742 33190089 11973335 23273993 19223551 28648376 30836930 18347063 26657156 21751375
SMCA2 ARI1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 11318604 31753913 8895581 24981860 16940996 12200431 26344197 14559996
SMRD1 SMRC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 24434208 12917342 33961781 20305087 26186194 24421395 24981860 18303029 22939629 26344197
SNF5 SMRC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 19650111 10078207 31759698 18809673 30108113 34133714 15150092 8895581 20305087 33961781 24981860 29374058 22939629 26344197
SMRD1 SMRC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 12917342 33961781 20305087 26186194 24981860 22939629 26344197
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CDC37 HS90B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25036637 28215707 24189400 23428871 26496610 22939624 33961781 27339980 11036079 25486457
CDC37 HS90A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 24292678 24462205 22939624 14718169 15647277 16335536 21871133 25036637 26496610 21745565 25486457 12176997 22729780 24189400 22504172 22315411 26804907 11413142 12930845 20159553 15001580 19875381 27353360 9685350 33961781 16611982 21360678
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
DAXX MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405218 18566590 18583933 16845383 15364927 20195357 28875283 23038753 21134643
SUMO1 DAXX â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11948183 17081986 23395904 18583933 30958586 16475184 12150977 20972456 20927612 25409927 21816224 28851805 21474068 11112409 22578841 31879127 19465479 21383010
DAXX HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 24550390 12529400 10669754 29084956 32545337
HDAC3 NCOR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16917504 11466315 10944117 21258344 11509652 16195251 16469706 14722073 15601853 12628926 11931768 11804585 14527417 16980585 23752268 29523594 16713569 10860984 11013263
HIF1A CBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22219185 15154850 21602890 15615775 16543236 18426857 15527772 11959977 9887100 19880525 27934968 16579968 8917528 11983697 17382325 10202154 25517638
GSK3B CTNB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19576224 12051714 25241761 19107203 25897075 10228155 27902311 30181396 33431799 19061640 16039586 8638126 21743491 17318191 11251183 27684187 31286874 19303846 10330181 23602568 11835406 29568061 11193155 12114015 18687691 34352208 26359353 11818547 24451375 10074433 30711629 17510365 30923315 29045831 16365045 29789528 12000790
NCOA2 ANDR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12810069 10935543 16713569 15563469 33640491 10454556 12612084 14966121 12588987 15684378 9717843 14593076
BAG1 HSP71 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11231577 14517289 19229298 9305631 11101523 11741305
ARI1B SMCA2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22939629 31753913 24981860 12200431 26344197
ARI1B SMCA4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30962207 22939629 21118156 20086098 15170388 24981860 31043422 29374058 12200431 26344197 11988099
SMCA4 ARI1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12368262 11780067 15170388 23698369 20460684 18086889 16287714 30962207 9845365 8895581 23540691 22939629 15985610 12200431 26344197 14559996 11988099 31759698 22140357 24981860 31043422 29374058 9584200
SMCA4 SMRC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 10078207 12368262 18809673 20305087 11726552 18086889 20460684 30962207 9845365 8895581 23540691 22939629 15985610 26344197 14559996 22573825 33961781 24981860 31043422 29374058 9584200
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PIAS2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
HDAC3 NCOR2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
UBC9 SUMO1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 21518904 22411991 25416956 21949651 17956732 32296183 18691969 16732283 18211895 10961991 21212807 9497385 26496610 24352468 11735126 19684601 17491593 14673145 26264872 9920803 17353931 19785004 23871147 9353268 17938407 16524884 26344197 12924945 16494873 8921390 16713569 18264111 21174150 15931224 25502805 18359863 20501649
SNF5 SMRC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 10078207 18809673 21520050 15150092 24421395 19650111 30108113 11238380 8895581 22939629 24434208 31759698 31631027 33961781 24981860 9584200 9744861 16568092 26344197
SMRD1 SNF5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 32296183 18042045 31759698 30108113 33961781 20305087 26186194 24981860 22939629 26344197
KDM1A RCOR1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MLL2 ASH2L â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 ASH2L â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
AKT1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17428466 20832017 20085797 21242970 17570479 10542266
BRCA1 FHL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 14550570 25184681 14986435
CCND1 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
TAF1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15870300 10086334 22711989 12569092 15893730
SP1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10497251 22911796 19850937 9236224 17617380 9407106 15870300 22415074 10850422 9584162 10908361 22734486 16267018 9637785 19755513 11410592 11024050 15922873 12794082 20435036 22334592
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
STAT3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16510571 19880237 17997399 15469392 16651438 21163886 22566696 16912181 22349830 16384639 12147685 21344490 20160059 19506034 20332458 23329648 11114718 17761947 22218594 15994929 21172343 18988190 18177723 24499623 21435102 19926637 18184402 17344214 22313388 23950841
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
GSK3B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 26907733 16944320 27546592 11967263 14663202 8524413 16504004 29969496 19767775 21347341 25142862 11311237 30736789 14597415 25591548 19645770 10385618 20548028 10766840 10929713 23565238 16039586 17570479 18818515 18167338 12615961 12413951 17046823 19071090 18598945 15465828 19374252 26121043 26432751 18319725 12969793 23733133 22922870 24134204 10486203 12459251 15020233 18769147 10910956 11152665 21317297 20537194 22099186 18328826 11124803 17070615 19757160 22470469 23552696 16732330 27695879 29554905 16103118 15075324 14536078 9832503 28090171
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
CDK7 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7533895 19847258 12814430 17386261 16782892 17884153 19667075 15703371 12648680 11900249 12459251 16697054 19809470
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
FOXO1 CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20200974 19050291 15632117 15565601
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
SMAD3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18391971 15084259
SRC GAK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28135906
SP1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20130956 20144149 17882273 15647279
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
GSK3B KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22539723 17570479 21658600
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
KAT5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12551922 16713569
RCOR1 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21300290 18806873 24217620 11102443 21258344 20389281 11171972 21142040 21670149 19703393 17537733 21602794 16885027 26226427 12032298 20164337 17218267 16140033 22143567 17687328 16956976 16079794
HDAC3 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC3 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
PAK6 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 11960368 11923280 18467333 22349818 23132866 11504915 11715018 28196907
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
PIAS4 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12815042 12904571
PIAS4 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12815042 12740389 12904571
PRKDC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 318.0 1.0 Omnipath 27120806 14555685 20028775 20176926 11287317 27542271 26740621 11731414 12393602 34197700 17993646 21940452 21946537 11278872 22975685 16908595 18316359 34073781 24735537 18039660 24652283 20856200 26170313 21300025 15388791 19144640 26297026 17545609 33941854 16280327 10625301 33845796 25918246 34385295 17537996 14645219 20804212 15084259 12169689 21795477 22071574 23913047 34021259 21695150 15684384 33958720 14530366 16670089 19487463 19223464 17303569 25481872 15475446 17116771 28967905 33753495 12438236 29562639 16753042 33836561 19073147 15169778 16891474 19477925 16338973 16397245 34562454 15821749 33767437 34087103 11409731 18381446 15737995 27481935 11313365 26700621 17210635 25447541 33931486 17827393 17126298 15262962 28542588 33574930 11821945 20471940 15461589 17077177 33579227 26921343 17386266 33744230 26848618 12944390 33566837 26902421 21042280 21763421 34380642 18321849 14593122 25775124 25739674 17229808 26351843 24102046 23757022 33532186 16043647 24632620 12781924 25738875 10864894 17974989 25719244 15806160 16497987 25851605 20501647 18439899 28209968 10973320 24819169 25745998 34383763 19592491 19244117 19204084 29088759 26871475 34257082 26755732 17237292 17709744 17640984 34405859 18480058 33995548 22310280 20211239 12052823 22580611 31937616 19920202 26745759 15905173 12499277 15028555 27162341 21106850 33562475 30065170 23462102 15678105 15642728 27065332 28558072 28977846 15319269 21339742 15855334 21045808 20145118 21297104 18632646 17379600 15471950 23474758 26887938 11375271 20013032 18701889 16540596 15314172 28515473 15964826 19638206 25892239 28692056 20530876 27505672 25100728 21242970 17297446 10542266 14670178 15548374 33741342 12429574 11002428 15831486 17116756 25435370 32833881 11402048 25361894 15207915 20729916 15625077 18677106 12869565 11250155 21356307 15967841 31936857 25943101 18394555 12644590 14500543 18691549 27197158 15623569 33477794 12062056 16754797 15383526 21909137 21949775 20085797 16807298 15899889 33868961 23940660 23434580 33927349 23899556 14990993 12000752 27880719 26065416 19060924 34520759 14679308 15334055 17283158 25257795 17548608 30586628 24437487 20124472 15289327 23325788 21208159 33664452 31679687 12791703 15047712 17166829 26146988 17329400 20660158 21532621 21806543 20179209 25661488 20957047 17562705 19915805 12606948 17277771 10377409 25893295 17270736 16407838 20597130 15047168 28658616 16357520 15537647 12818176 11425855 17210830 19800394 12506011 21310961 16963136 21996732 15695828 33835469 11701613 19010331 26686089 28915558 15467762 17586693 18456663 34381564 18765673 20233713 34208786 11029403 22084251 20622007 12077256 11313948 16917505 19448664 27391337 15792956 21172654 15608670 12438239 19875458 22014578 25071014 11809760 18728186 31391321 33891611 19805619 33407730 25868858 25320242 34348155 20832730
STAT3 HIF1A â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19265129 18644974 16007214 20924113 17597020 23991099
NCOA1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11773079 16713569 15313931
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
STAT3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15735682 18985005 10973499
SUMO1 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
PIAS2 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16204249 21988832 25416956 19217413 16189514 14609633 16524884 12764129
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
MLL2 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD4 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
PIAS1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14514699 21988832 23331499 15028714 15231748
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
NCOR1 SMAD3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD3 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
GSK3B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 18172167 21071413 21310903 23077590 28756206 19114991 19002158
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
TLE3 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
FOXA1 HDAC1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
NCOR2 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11509652 17694085 11804585 22230954 10944117 16924111 17126328 15837933
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7499226 16798740 23533633 14736735 18216279
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
SPOP DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21988832 21573799 16524876 19818708 15240113
SRC CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27432652 16619028 19470771 27109099 27195913 19383910 30501030 24100030 22074016
HIF1A CAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
SP1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15531587 10684646 23280667 21631282 17108117
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
GSK3B SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18045539 25241761
GSK3B HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21118993 18045992
NCOA2 NCOA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
GSK3B CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 16944320 11967263 14663202 8524413 8861947 16039586 17570479 14536078 12615961 19561641 15465828 25241761 18691976 18319725 12459251 15020233 20537194 11124803 16131838 9832503 15364936
SPOP NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23559371 24239470 21577200
SMCA4 SNF5 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 19164553 9128241 10078207 12368262 18809673 18414052 21520050 15150092 19448667 30108113 29374058 11726552 20460684 16287714 30962207 18042045 9845365 11238380 8895581 11486022 23540691 15985610 22939629 26344197 14559996 20506188 22573825 31759698 22140357 16687403 23602572 24981860 33961781 31043422 9744861 9584200