Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
SMARCA2 CXXC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 ACTA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17409411
YY1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21169469 23705901
POMC OPRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7905839 8208289
YWHAG VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PTEN CXXC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
IGFBP3 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CXXC1 TBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HNF4A TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805548
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
CXXC1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21765426 20410295
KLF2 RELN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21530336
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST2H4A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DPY30 HIST2H4A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
DPY30 HIST2H3C â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HIST2H4A RBBP5 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
KLF2 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21482710 15136591
HIST2H3C RBBP5 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CXXC1 MEN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18082152 24981860
MYC KCC2D â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC PESC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC WDR82 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
HCFC1 SETD1A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
MLL2 DPY30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17178841 24981860
SET1B DPY30 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
CXXC1 MLL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18082152 24981860
PI42A CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PESC CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RING2 CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 26496610
KCC2D CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZN408 CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RSBN1 CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E41L5 CXXC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CXXC1 H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18082152 30804502
HCFC2 OGT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK BD1L1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK E41L5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MK SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SET1A ELF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 31076518
KCC2D SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PESC SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RSBN1 SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E41L5 SET1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PI42A SET1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KCC2D BD1L1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PI42A E41L5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
E41L5 BD1L1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HIST2H4A WDR5 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HIST2H4A WDR77 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST2H4A KMT2A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
PPP1CA RB1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DPY30 MEN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23508102 24981860 17500065
MYC HCFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31767764 35140242 30415952
BD1L1 RBBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31076518 26496610 23508102 33961781 24981860
WDR5 BOD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23508102 33961781 26186194
CXXC1 DPY30 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23995757 26496610 23870121 23508102 24981860
HIST2H3C KMT2A â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
NUP50 CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRS6A CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EDA CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ANM2 CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HCFC2 CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
PRPS1 CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BD1L1 CXXC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 23508102 33961781 24981860
CXXC1 BOD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23508102 33961781 26496610
EDA SET1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRPS1 ELF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HCFC2 BD1L1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
HCFC2 SET1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
NUP50 SET1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRS6A ELF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ANM2 SET1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ANM2 SET1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BD1L1 SET1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 26496610 31076518
WDR82 SET1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27563068 20516061 23870121 17355966
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
P53 BAG6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22653443 31647545
EP300 WDR82 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33742100 23870121
OGT1 WDR5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27705803 23353889
KCC2D OGT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
ASH2L HCFC2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
BAK1 TP53 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST2H3C HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HCFC1 MEN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
MLL2 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17178841 24081332 31076518 30107592 17925232 15960974 24491801 27563068 17500065 23508102 33961781 24981860 16603732 29785026 30604749
OGT1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23508102 31076518 27705803 23353889
HCFC1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31076518 23508102 33961781 20305087 24981860 22939629 15199122
P53 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15960975 19433796 23870121
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
SET1A DPY30 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31076518 17500065 23870121 23453808 24981860
OGT1 CXXC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23508102 27705803 23353889
OGT1 SET1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29474905 31076518 27705803 23353889
ASH2L HCFC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KMT2A MYB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BOD1L1 CXXC1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
EP300 H4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11163245 16096645 30804502 16109717 25728767 11884585 15951563 15611041 11830591 28465257 16415179 11689053 15308690 28844863 26625199 15136563 17982102 18397880 12499368 23587423 20368990 11689448 12237408 11983172 16717280 14752096 22100137 14612423 8945521 16287840 18418072 30902546 15834423 23934153 14585496 11691934 10607594 16332960
HCFC2 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 15199122
MEN1 RBBP5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 17050672 14992727 15199122
MYC TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15723054 8755740
H4 DNMT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30804502 30021884
WDR82 ASH2L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31076518 20516061 23870121 23508102 24981860
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
MYC PRS6A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 21988832
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
WDR5 BD1L1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194
DPY30 HCFC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 23995757
PTEN P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12620407 16713569 18339852 24141722 14559824
CXXC1 HCFC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 23870121
HCFC1 SET1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17998332 31076518 27563068 24981860 12670868
NUP50 BD1L1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
NUP50 KIFC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 26186194
P53 ASH2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19433796 33961781 23870121
SET1B ASH2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17998332 26496610 27563068 23508102 33961781 20305087 24981860 34079125 26886794
OGT1 ASH2L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31076518 27705803 23353889 23508102 34079125
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
RBBP5 DPY30 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23995757 31076518 17500065 23508102 24981860 20305087 31485071 25456412
MLL2 H4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30604749 30804502 31127101
HCFC1 HCFC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 24981860 15199122
CXXC1 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32807901 23870121
SET1A P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29474905 31076518 23870121
SET1A WDR82 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17998332 17355966 31076518 20516061 27563068 23870121 29474905 24981860
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CXXC1 DPY30 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DPY30 SETD1B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MLL2 ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17178841 31076518 30107592 17925232 12482968 24491801 27563068 23508102 33961781 24981860 16603732 34079125 32350066 26886794 30604749
MEN1 ASH2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23508102 24981860 17050672 14992727 15199122
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MEN1 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15960975 27705803 23508102 24981860 14992727 15199122
NFYC MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
SET1B RBBP5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17355966 31076518 20516061 26496610 27563068 23508102 33961781 24981860 29785026
HCFC2 RBBP5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31076518 23508102 33961781 24981860 15199122
WDR82 RBBP5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31076518 20516061 23870121 23508102 24981860
HCFC2 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 33961781 24981860 26186194 15199122
WDR5 DPY30 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23995757 25666610 17500065 27705803 24981860 20305087 33022573 31485071
CXXC1 WDR82 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19410543 18680430 20516061 23870121 23508102 24981860 19433449
KRT75 VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SET1A ASH2L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17998332 31076518 16253997 23870121 27563068 23508102 23453808 20305087 33961781 29474905 24981860 21653943 34079125 22939629 26886794
CXXC1 ASH2L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19410543 18680430 31076518 16253997 23870121 26496610 23508102 33961781 20305087 24981860 34079125 18082152 19433449
ASH2L HCFC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23508102 33961781 20305087 24981860 34079125 15199122
ASH2L DPY30 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 23995757 31076518 17500065 19556245 23508102 33961781 20305087 24981860 21516116 23414517 31485071 22231628 34079125 25456412
ASH2L WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31544921 17925232 16253997 20305087 21285357 15960975 21531708 15199122 17178841 25666610 16892064 15960974 18066051 23870121 23508102 21884981 32076268 33022573 22939629 16878130 31076518 27705803 19556245 17500065 19131338 33961781 24981860 16603732 26186194
ASH2L HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31076518 23870121 23508102 33961781 20305087 24981860 12670868 15199122
ASH2L RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 31544921 17925232 12482968 16253997 21124902 20305087 21516116 21285357 32296183 21220120 15199122 17178841 16892064 15960974 23870121 23508102 26886794 16878130 31076518 17500065 19556245 19131338 33961781 24981860 16603732 23414517 34079125
TP53 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 15077116
EP300 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9809062 15295102 21471221 26229107 15337767 23010591 18485870 15558054 22266186 15509808 26625199 9194564 23402884 23870121 17438265 16959611 12690203 17906639 24821727 15664194 21187340 33196849 17977830 11804596 25288747 15186775 18612383 23796514 19234109 27818144 19339993 24157709 9652736 28757384 12499368 17452980 9891054 23880760 31167125 15542844 22013068 16713569 9288740 17189186 11782467 16543236 23329847 10942770 26302407 23307557 22074660 19218448 19217391 10601022 16024799 16782091 12501250 11433299 22731250 23728348 10518217 9194565 25651062 12724314 14612423 16611888 19805293 18243116 32807901 29706626 20234175 16678111 14759370 25867071 25156994 11907332 16438982 16135789 11070080 11359905 25753752 16537920 9744860 18391200 15965232 10490106 16928824 12162806
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
MYC CXXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
SET1A RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17998332 17355966 31076518 20516061 22147691 16253997 23870121 27563068 23508102 23453808 20305087 33961781 29474905 24981860 21653943 22939629 29785026
CXXC1 RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19410543 18680430 31076518 16253997 23870121 26496610 23508102 33961781 20305087 24981860 18082152 19433449
TP53 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530187 15456866
YY1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19402223 20430007
YY1 WDR82 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
YY1 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8661027 23000143
HCFC1 WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 27705803 24981860 20305087 22939629 12670868 15199122
SET1B WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17355966 22266653 26496610 27563068 27705803 22665483 33961781 24981860 26186194 33022573
CXXC1 WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19410543 18680430 16253997 23870121 26496610 27705803 23508102 33961781 20305087 26186194 24981860 18082152 19433449
WDR5 MLL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17925232 15960975 22266653 22665483 17178841 24788516 15960974 24491801 33022573 22689669 30107592 27705803 27563068 17500065 33961781 24981860 16603732 26186194 32350066 30604749
WDR5 SET1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 28514442 17355966 31076518 22266653 16253997 23870121 27563068 27705803 22665483 23453808 20305087 26186194 33961781 29474905 24981860 33022573
HNF4A VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568083 12750294 19671543
OGT1 HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20200153 32994395 21285374 27705803 22939629 12670868 21295698
DNMT1 MT1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16329111 22905112 12417732
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
TBP P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8395834 16713569 11313951 8083962 10359315 9349482 10601022 12379483 8405994 1465435 7799929
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
HNF4A P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16713569 35140242 33961781 11818510
HNF4A NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17317687 11741883 16479620
MYB CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10590070
CXXC1 SET1B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17355966 18680430 26496610 23870121 27563068 23508102 33961781 24981860 22939629 19433449
CXXC1 SET1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17998332 19410543 17355966 18680430 31076518 16253997 23870121 26496610 27563068 23508102 19951360 23453808 33961781 29474905 24981860 18082152 19433449
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
MEOX2 WDR5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CXXC1 WDR5 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
DPY30 KMT2A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PPP1CC WDR82 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CXXC1 WDR82 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DPY30 SETD1A â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
PPP1CA WDR82 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
WDR82 WDR5 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 20516061 27705803 23870121
WDR5 RING2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 15960975 28514442 27705803 22325352 33961781 24981860 26186194
CXXC1 SETD1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SETD1B WDR82 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CXXC1 SETD1A â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
CXXC1 RBBP5 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
ASH2L CXXC1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SETD1A WDR82 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ASH2L SETD1B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ASH2L WDR82 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RBBP5 SETD1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ASH2L SETD1A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RBBP5 SETD1A â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DPY30 WDR5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RBBP5 WDR5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 31544921 17925232 16253997 20305087 15960975 30089852 21531708 21220120 15199122 17178841 25666610 31685992 15960974 27320920 23508102 21884981 32076268 33022573 16878130 28813667 17041588 31076518 17500065 19556245 27705803 24981860 33961781 16603732 26186194 31400120
SETD1A WDR5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SETD1B WDR5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MLL2 ASH2L â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 ASH2L â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
TP53 BAK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22983126 18519674 21233848 15033822 15489892 15105295 10741712
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
TP53 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21611785 11713584 10365096 15217513 16258956 14675138
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
PAK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14722118 11895474 17081983 16565220 26369929 28390425 27457922 11420699 15713670 15766329 7983050 12458200 12761892 26956613 16964243 28096473 15345747
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10529175 24297337 11852084 24737129
TP53 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10101800 23810988 15661074 7566179 15713654 18084616 9525742 20003326
TP53 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11131279 11092782 9194524 8637893
TP53 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17350573 18510673 19098008 19449448 17630965 24917821
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
TP53 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7566179 17409411 18431400
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
YY1 OPRM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17990281 19164126 19765550
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
MLL2 WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
POMC OPRM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15464143
MLL2 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
KMT2A HOXA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18082152 15941828
PPP1CA RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12202491 8380224 17274640 10773440 9315635 17008050 20694007 8384581 16189514 8380637 10889204 12434308
CCNA1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7575488 18590585 17303408 10022926 16189514 17660363 15279786