Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MRE11 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
PPP2R1A CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
CDK5RAP3 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19223857
CDK1 TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25688093 29052541
CHEK2 MRE11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 RNF168 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 MRE11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
RSL1D1 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TCOF1 FMR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 IMPDH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7896827
SP1 MNDA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8809111
ZCCHC7 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NPM1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 SENP3 â—¼   COLOCALIZATION 2.0 0.8 intact 6541703 18259216
FMNL3 RPL19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RRP1B CTCF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RSL1D1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RSL1D1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ZNF131 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23404503 22467880
MRE11 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NF1 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
SUMO1 CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19029252
SUMO1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12769861 12679040
THOC5 PPIL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CDH1 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HBB HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HBB HBA2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PPP2R1A MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
CTBP1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21681822
LRRK2 DIDO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 USP39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SP1 PPP1CC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9028876 12684058
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
FRK ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
RPL10 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
PPP1CA IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
PPP1CC IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
RPS8 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NR2C2 MAP3K14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16050801 12243350
HSP90B1 KIF15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPS8 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CTNNBL1 PRPF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CHD3 SLC25A6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHD3 KIF15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SRPK2 CTNNBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NR2C2 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11844790
NR2F2 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
CTCF NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21111075
LSM2 USP39 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EIF2D RPS8 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EIF2D RPSA â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CDK1 CDK7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20360007 11113184 16327805
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
RPS8 UTP18 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
IMP3 NOP56 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
IMP3 WDR3 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
IMP3 WDR46 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
UTP18 WDR46 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
RSL1D1 WDR3 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SNRNP200 USP39 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
LRRK2 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
DAXX CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24981860
NR2C2 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30463901 34079125
ESR1 EP400 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21182205 31527615
G3BP1 FMR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26777405
LRRK2 MMS19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
ESR2 PI4KA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 25604459
CHD4 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 20926688
RRP1B RRS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20926688 33961781
RRP1B NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
ESR1 RRS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
RRS1 RBM34 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RRS1 SRSF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HCFC1 SETD1A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
NOP56 TOP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 12777385
BMI1 NCBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
MOV10 CDC20 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
LRRK2 RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21454543
RHOA RPN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 21988832
LRRK2 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 PTCD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
MOV10 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20543829 34316702
BMI1 G3BP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 DIDO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 YLPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 G3BP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
G3BP1 FUBP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26777405
NOP56 SENP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
ESR1 POP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21182205 31527615
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 MOV10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
IKZF3 CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
MOV10 SRSF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
RBM34 NVL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MRPS16 PTCD3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
MRPS14 MRPS25 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
MRPS14 MRPS22 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PPAN RRP15 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
EIF3H RPS8 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
NOP56 RPS8 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ARHGEF1 RHOA â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 10836144
CDC20 CDK1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PPIL1 SF3B5 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CBX3 CHAMP1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
SRPK2 CDK7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32707033 23602568
SENP3 RRP1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20926688 33961781 26511642
TAF5L TAF9B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
EIF3H RPSA â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
EXOSC7 ZCCHC8 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CTBP1 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 24981860
ESR2 SRSF5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29509190 21182203 25604459
BTF3 RPL15 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
PPP1CA RRP1B â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
BTF3 RPL19 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MRPS16 MRPS22 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CDK1 CDC20 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 10799291 26912231
ESR1 GNL3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
ESR1 SUMO1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 15961505
TAF9B TRRAP â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ESR1 PTCD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 DDX27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
SRPK2 DIDO1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26167880 33961781 23602568
CHD4 CHD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28977666 32744500 24981860 22939629 9885572
MOV10 FUBP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29395067 30833792
NOP56 WDR3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ACTN4 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21078666 19805454 25604459
NIPBL CBX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 15882967 20850016 28167679
HCFC1 MEN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
PPP1CC RRP1B â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
ESR2 PTCD3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29509190 21182203 25604459
PPP1CA YLPM1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
GNL3 NOP56 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
DDX27 RBM34 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
FMR1 FUBP3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 26949739
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
NOP56 RRP15 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
NOP56 KRI1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
NOP56 POP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
SRPK2 SRSF3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26167880 33961781 9472028 23602568
NOP58 RPS8 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
DDX27 PPAN â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HBA2 HBB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
RYBP CBX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34316702 27705803 22325352 33961781 24981860
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
PRPF3 LSM2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29395067 33961781
ESR2 MED12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21182203 11867769
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
G3BP2 G3BP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26777405 26186194 29395067
NOP56 UTP18 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
IKZF1 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 30760870 11003653 12015313 33961781
CHD4 IKZF1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RRS1 RSL1D1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
SP1 SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18239466 18572193
MAP1B LRRK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24754922 21159966
NOP56 RBM34 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
NOP56 DDX27 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
DDX54 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12466272 21182205
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
SRPK2 SRSF5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 33961781 9472028 23602568
RBM34 DDX54 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
RBM34 DDX31 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
RACGAP1 SHCBP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BTF3 RPL10 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CBX3 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 28977666 21888893
EP400 TRRAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29028833 11509179 26496610
NOP56 GNL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 26496610 34079125 12777385 26344197
NOP56 RRS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 34079125
TRRAP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31527615 11931763 16260778 12738788 12837248
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
CHD3 IKZF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10204490 30760870 33961781
HDAC9 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11022042 16713569 20361981
PPP1CC YLPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PRPF3 USP39 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CDK1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21900237 23354023
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
PI4KA C8orf33 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SUMO1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
LIMK1 RHOA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11018042 16219803 10652353
ESR1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26487511 11867769 31527615
HCFC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12670868 10976766
GSK3B BRIX1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPP14 DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 EIF2D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
FAM83D GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHD3 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
IKZF1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKZF1 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21900206 16189514 25416956 16713569 10766745 24722188 27107012
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CTBP1 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
LSM2 SF3B5 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PRPF3 SF3B5 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
SF3B5 SNRNP200 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RPL10 RPL26L1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RPL15 RPL26L1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
RPL26L1 RPS8 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
NOP56 WDR3 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 26496610
NOP56 DDX54 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 26496610
NOP56 RSL1D1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RSL1D1 UTP18 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MRPS16 MRPS25 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
NOP56 WDR46 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDC40 TFIP11 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
NOP58 UTP18 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
WDR3 WDR46 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
IMP3 UTP18 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
IMP3 NOP58 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NOP58 WDR46 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
UTP18 WDR3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SUMO1 TOP1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 12149243 12439742 11709553 24654937 15576338 19596686
DDX27 RBM34 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 26344197
ESR1 NR2F2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS22 MRPS25 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS22 PTCD3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PPIL1 SNRNP200 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
EP400 TRRAP â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
NOP58 WDR3 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
TAF9B TAF6 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22939629 15899866 26344197
TAF6 TRRAP â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
NOP58 RSL1D1 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
RNF2 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16710298 5218667
NOP56 NOP58 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 26496610 17636026 34079125 12777385 26344197
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
TAF5L TAF9B â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
INTS5 INTS7 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CDC40 SF3B5 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SUMO1 DAXX â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11948183 17081986 23395904 18583933 30958586 16475184 12150977 20972456 20927612 25409927 21816224 28851805 21474068 11112409 22578841 31879127 19465479 21383010
TAF6 TAF9B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDC40 PPIL1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RPL10 RPL15 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL10 RPS8 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LSM2 PRPF3 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MRPS14 MRPS16 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CDC40 SNRNP200 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL10 RPSA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL15 RPSA â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPS8 RPSA â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
LSM2 SNRNP200 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NOP56 NOP58 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RPL10 RPL19 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL19 RPSA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PRPF3 SNRNP200 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL15 RPL19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL15 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SP1 ATP2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12818568 8621466 17597815 14613864
ATRIP MCM3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP MCM3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP MCM3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
SP1 BRD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16792505 18778484 19111069
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK1 CDC20 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
CDK1 MCM3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
GSK3B CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9832503 17359287
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 KIF20B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470801
CDK1 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7575488 18590585 17296725 17303408 18524952 17242355 17102137 17116885 19793801 17582221 17660363 15279786 21658608
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
PLK3 CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21376736 10973490 16481012 17918214 12242661 25404613 16189514 11901158 12493754
SP1 FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10612627 16886907 9328468 15479157 15175277 16500891
MEN1 CDH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
SP1 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21611785 22890831 22125028 20963645
MRE11 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP1 SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12149243 11709553 25114211 10759568
SUMO1 NOP58 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20797632 25114211 21647297 12196509 19596686
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CTBP1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15169839 17615296 21416054 22796940 20818389 21685935 22370643 20519943 12508111 17508028 11309385 19597490 14673164
GSK3B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16944320 11348595 11967263 14663202 8524413 20080742 19797085 12040186 16611981 10671551 16039586 12615961 15465828 17928543 24063632 10671552 15020233 19575820 17444818 20537194 17052453 9832503 18455992 16371461 11274345
ARHGEF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 12748184 32203420 9113980 9641915 10836144 11149925
SP1 ALDOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8524331 10023068
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 ZBTB7A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19444642 23027183 19723341 18368381
SP1 UTRN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11237613 15172107 11997063 10871758
BMI1 RNF2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BMI1 RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16710298 22493164 22902369 20068231 22325352 25355358 17157253 16751658 26496610 16714294 26468281 26151332 12183370 12589020 21772249 25843776 20601937 32296183 21676867 27647897 15563468 27705803 16359901 24457600 19636380
GSK3B MAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 27849007 25775433 15731007 17570479 9570753 25040932
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
NR2C2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11844790 10611280
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105