Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
EGR1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12690110
MYC DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14519204
MYC ADM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9973255 15192039
MYC KPNA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 35044719 17093053
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 EGR1 â—¼   COLOCALIZATION 2.0 0.8 intact 5216887 14744935
TP53 DUSP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12890671
DMTF1 AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
JUN AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22570239 20308529
EGR1 AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20190820 20103632
SMAD4 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 JUNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
FOS SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11854297
DMTF1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21421563
SMAD4 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12622415 18505344
JUN DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20702711 19585511
JUN DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15601844 12489182
DMTF1 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
DMTF1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
EGR1 DUSP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11165042
DMTF1 ATF7IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DMTF1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
JUNB DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15601844 15308641
MYC ECT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
EGR1 TP53 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
SMAD4 JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10220381 25609649
FOSL1 JUNB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
SMAD4 JUNB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 10220381 15231748
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
JUN BCL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 10497212
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MYC BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
TP53 BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12808109 24189068
MYC MBD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD4 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278818
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
FOSL1 JUN â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
JUN JUNB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 25609649
JUNB FOSL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32296183 16189514 23661758 24029232 33961781 12371906
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
JUN FOSL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23661758 11912197 24029232 9160889 20511396 33961781 26258633 11708771 11431474
FOS JUNB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 16511568 23661758 20211142 24029232 26496610 1406655 35140242 20195357 33961781 25609649 26186194 15867431 20102225 10764760
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
FOS CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12705898 12087103 14755691 16141357 10891399 11789587 21864583
SMAD4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10878024 9618481 9865717 11786386 9307274 24052079 12429655 10962574 10415848
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
JUN CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11136975 12717415 21278055 10506225 19628677 12054510 18094076 10072388 18210215 10733944
EGR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18316600 20368687 19508870 24384380 17307334 11502738 12690110 21642427
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
SMAD4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 9618481 17550342 12545156 11013220 15155580 11074002
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
DMTF1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21892281 10097151 22039255 21062982 15601844 17546045
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
JUNB CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16966326 19340300 17370299 10856241
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 20876797 10871348 18583030
MYC JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2123531 7775604 12695333 18838534 18414489
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
EGR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9242687 17822668 15958557 12755686 16990849
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
TP53 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11514734 18555006 10953306 14741382 19107228 20124454 8274455 16061648 10448271
TP53 DUSP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8702807 20196119 15611668 18403641 23149933 12890671
TP53 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12609716 10719731 10101800 24195060 10029407 16406676 19826414 9833779 12719977 9017002 22028325 10224095 9849855 7521539
EGR1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15225550 14744935 11251186 16713569 12384981
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SMAD4 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9732876 10942775
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
JUN FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18435914 15806162 13679379 17082637
JUN BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9257196 2124710 15831452 17308994
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9160889 11708771 23661758 20511396 11431474 24029232 11912197
EGR1 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20635349 7798257 18757417 24053448
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
FOS FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8446579 13679379 17371847 15514944
FOS BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9610372 10804019 2124710 8828501 1749528
DMTF1 DSPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17196192 23349460 16679514
DMTF1 DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16878159 17196192 22549196 16679514 21062982 15601844 15108359