Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 MTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23552838 22286760
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
HIF1A MTA1 â—¼   COLOCALIZATION 2.0 0.8 intact 5218395 16511565
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
NCBP3 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CTCF NCBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
B2M HNRNPC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RAN RANBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9637251
ESR1 AICDA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23181348 19139166
ARRB2 NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A1 HIF1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17382325 5219810
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
CTCF WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24534946
NFE2L2 CUL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21793854 20452971
DAXX TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 14557665 5216762
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
FAM50B KPNA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LRRK2 FAM90A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 NUP50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HSF1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19793920
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
NOTCH1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
HIF1A NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
HIF1A KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
HIF1A RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19132225 20001745
HIF1A NKX2-5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21055290 18303027
TARDBP HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KPNA3 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 HNRNPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18296503 21317560
HSPA8 KPNA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT5 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KDM1A SMARCD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RELA KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19208907 23423566
NPM1 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RECQL KPNA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9168958 6549592
MYC KPNA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 35044719 17093053
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
LMNA NUP153 â—¼   COLOCALIZATION 2.0 0.8 intact 20561986 7893748
TARDBP MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10644343 16847353
MYC RAN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23468463 11085504
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RELA NCOR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17876798
TP63 NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20442293 20950370
NOTCH1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17537801
SOX2 NTRK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22265740
NXF1 NUP153 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10668806 5212227
RAN NUPR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16478804 0508955103
PARD3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22653443 8415349
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
RELA RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RCC1 RAN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7878053 1944575
TGM2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9315663
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RYBP TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCD1 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
CSE1L KPNA4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
H3F3A SMARCD1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
KDM1A KPNA4 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
SOX2 MTA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
HDAC1 ADNP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 23752268
ESR1 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26487511
CBX3 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
LRRK2 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
DAXX CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
MYC CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
DAXX CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
ESR1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21182205
SOX2 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30442713 28794006
MYC MRGBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 35140242
MYC NCOR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC NXF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
KPNA4 RANBP3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DAXX H3F3A â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DAXX ADNP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 24981860
MRGBP EP400 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15647280 12963728 28514442 29028833
ESR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17289570 23403292 31527615
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
SOX2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
NUPR1 RAN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16478804 19650074 32780723
CBX3 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 H3F3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 MTA1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
IPO4 KPNB1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
BCOR HDAC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23658227 16713569 10898795
MYC HIF1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15071503 28205554 28628118
RAN NXF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12384575 10228171
CBX1 H3F3A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CSNK2A1 PML â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
KPNA3 RAB28 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
MTA1 TP53 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
NUP153 RAN â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
MTA1 CUL4B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34026424 26028330
CUL4B HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25189618 34026424
DAXX HSF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15016915 20620219
LMNA NUP50 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 24927568 22412018 34079125
NCOR2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10944117 11013263 16033423
H3F3A IPO4 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
KPNA4 SOX2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CUL3 NUP50 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
SOX2 EP400 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
NCOR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9171229 20392877 12738788 14715875 23403292 9702189
SOX2 FOXK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
FOXK2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 27773593
FOXK2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 27773593
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
KPNA3 RCC1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
MYC ADNP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
CBX1 ADNP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21888893 24981860 27705803 20850016
CBX5 ADNP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21888893 20562864 24981860 27705803
RYBP CBX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 34316702 27705803 22325352
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 FOXK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25740706 31527615
FOXK2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 24748658 27773593
HDAC1 VHL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC IPO4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
MRGBP KAT5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 18218781 12963728 27153538 26186194 17573780 28514442
MYC KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 23455924 32296183 29467282
SOX2 NCOR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 28794006 23667531 21532573
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KAT5 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
KPNB1 RCC1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
KDM1A MTA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21670149 19703393 26028330
MTA1 ZNF423 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
FAM50B KPNA4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
NCOR2 PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11585900 11430826
CSE1L KPNB1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
NUP107 NXF1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
FAM50B ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CBX3 TRIM28 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BCOR RYBP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HIF1A MTA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16969516 16511565
CBX3 ADNP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 29795351 34079125 27705803 32533114 21888893 20850016
MYC PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17146439 21150319 32592588 30415952 15735755
FAM90A1 KPNA3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DAXX TP53 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
KPNB1 NCBP2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
KPNA3 NCBP2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CBX1 TRIM28 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 34026424 24981860 16511565 22939629 26496610 9885572 27098840 26344197 21258344 10840944 14722073 26028330 12920132 33264408 17922035 28514442 16189514 26949739 18451879 11146623 23752268 20585571 29997244
MTA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18451880 16807247 12167865 11146623 12639951 31527615
BCOR HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 10898795
CBX5 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 15306854 17314413 34079125 20562864 11336697 16713569 19498464 27705803 21888893 20231385 20850016
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CSNK2A1 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21245376
HIF1A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19342889 20138114 19940121
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
CTCF NFE2L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
MYC EP400 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 18413597 21150319 29467282 30415952 20946988 17314511 11509179
EP400 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20351180 14966270
NCOR1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16469706 17400812 12145334 16713569 12738788 21182203 24051437
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
NOTCH1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18722525 23331499 16256737
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
WT1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15286719 17634147 20842112
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
NOTCH1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
NCOR1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10882117 16713569 11430826
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
RCC1 TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9572484 11243407
WT1 SF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14580722 12213901 12130543
NUP107 NUP153 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
NUP153 NXF1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CBX5 TRIM28 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
KAT5 MRGBP â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RANBP3 RCC1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
KPNA4 RCC1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
KPNA3 KPNB1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
KPNB1 NXF1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
IPO4 RAN â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
KPNA4 KPNB1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
KPNA4 RAB28 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EP400 KAT5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
EP400 MRGBP â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
NUP153 NUP50 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
KPNB1 NUP153 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11545740 24981860 9933612 22939629 26496610 26382858 26264872 31448526 26344197 17190602 32814053 12374755 29997244 29101316 31467278 22365833 29395067 19668212 16189514 7478990 23665581 12434151
CSE1L RAN â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RAN RCC1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KPNB1 RAN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MTA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15226262 11146623 12527756 24413532
MTA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11146623 18451880 12167865 16807247
MTA1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
RANBP3 RCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11932251 9637251 16189514
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
CSNK2A1 CBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19657222
RB1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
TP53 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15145945 15988033 19235838 10516009 21478095 14984207 19427386
TP53 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21340684 20066118 20457558 20182602 6396087
KPNB1 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
KPNB1 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
CSNK2A1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17145710 16873060 19380586
CSNK2A1 NKX2-5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9858576
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21474068
CSNK2A1 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12659875 15302935
CSNK2A1 HNRNPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19651622 20058876 17081983 20166139 15687492 18691976 20068231 18452278 19664995 17693683 17287340 19413330 12564933 18669648 15302935
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
CUL3 NFE2L2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
DAXX TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12954772 21482821 21134643 16845383 25241761 15364927 16713569 12482984 15339933 23038753
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16574784 18006642
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
NCOR1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16469706 12738788 12145334 17400812 16713569 21182203
KAT5 EXO1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
HDAC1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RELA HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18498249 17898080 23185316
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
RB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15674338
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
PML KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19150978
KAT5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17188038 15310756 18280244 16601686
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
LRRK2 KPNB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
RAN KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 8909533 11024021 9214382 20658144 8576188 26496610 9102465 9135132 10944119 10037787 9045717
NUP153 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 35044719 10749866
TP53 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21611785 11713584 10365096 15217513 16258956 14675138
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC RCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9178906 14519204 9792927 12695333
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
NCOR1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
NCOR1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
RELA NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10777532 14982881 12589049 16382138
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
NUP153 NXF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10668806 16713569
RCC1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 26186194 10827954 11336674 18617507 10811801 29997244 31467278 16189514 7988569 10369786 20565941 1961752
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
EXO1 NRK â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
TP53 KDR â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368