Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BAG2 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7834747 8692945
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
HSF1 STIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22669480 20692357
SHC1 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
ERBB3 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
NFKB1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
HSP7C HS71L â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29568061
CHIP SYUA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32430178 18436529 21358815
EGFR APEX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
APEX1 YBOX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28986522 20856196
ATX1 BAG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32814053 25959826
BAG2 TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
CFTR BAG3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
BAG3 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 23824909
CDK9 HSP76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17643375 26209609
CDK9 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 17643375
EGFR HSP72 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24189400 23956138
BAG4 HSF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KDM1A HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16140033
RBX1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30349055 12481031
RBX1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30349055 12481031
HS90B CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 21145461
CUL4A HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 12481031
CUL4A NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30945288
SHC1 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
CRK HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
CRK HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
CRK GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
HS90B LCK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 31980649
LCK HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31980649
RIPK1 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 14743216
NFKB1 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
NFKB1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
NFKB1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
NFKB1 HSP76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 25609649
PRKN2 AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25959826 24244333
CFTR AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
STIP1 CFTR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20534503 31324722
CFTR CADH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
TXNIP HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27437069 31669268
TXNIP HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27437069 31669268
HS90A ERBB3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 24189400
ERBB3 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 24189400
ERBB3 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 24189400
SRRM2 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
HSP71 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20048054 1540595
HS90B ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32206096 21730179
CSN5 HS71L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 HSP76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CSN5 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18850735
CADH1 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16212417 25468996
HSP71 YBOX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25497084 22939629
VCAM1 STIP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MLP3A GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20562859 22963397
STK4 GRP78 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 23386615
GRP78 HS71L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22863883 22939629
VCAM1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
STK4 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 23386615
TRI38 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23414517 21988832
MLP3A HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20562859 22963397
HEMGN HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22712502 24740910
CLH1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33957083 26496610
HSP71 DJC13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 33957083
HSP71 EDRF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 33957083
VCAM1 CLH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
BAG4 DJC13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 HSP7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HSP72 EDRF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 33957083
HPBP1 DJC13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
STK4 HS90A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 23386615
VCAM1 HS90A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HS90A EDRF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 19875381
VCAM1 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
STK4 HS71L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 23386615
PRKN2 BAG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25959826 24244333 32929329
BAG5 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33957083 24510904 32850835
BCL2 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 10354271
CSN5 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19295130 30349055 18850735
SHC1 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31980649 19380743 24189400
SHC1 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19293945 31980649 19380743 24189400
RIPK1 TAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18299187 16603398 29955050 15327770
RHOA HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12490434 31980649
TAB1 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
CFTR HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22038833 26618866 17110338
HS90A BRAF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27034005 31980649 22939624 28146421 27684187
BRAF HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27684187 17979178 31980649
CADH1 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16212417 27684187 25468996
GRP78 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22863883 22939629 26496610
TOM70 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23414517 12526792
SC5A1 HSP71 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12082088 16713569
MLP3A CLH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20562859 22963397 24067654
M3K7 CLH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
M3K7 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
PRKN2 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939624 25959826 24244333 32929329
PRKN2 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32929329 25959826 14532270 22939624 24244333
ATX1 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32814053 25959826 17127076
TF65 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
STK4 HSP7C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26657153 23455922 23386615
HPBP1 EDRF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HPBP1 HSP76 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 33957083
FANCC HSP7C â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11500375 14499622
NFKB1 HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761 25609649
NFKB1 HS71L â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761 25609649
SOX9 HSP71 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 11356186
CFTR HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
CLH1 HSP7C â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 29568061
M3K7 HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 14743216
PRKN2 SYUA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16714300 18195004 32814053 19651786 11588587 25861987
CHIP GCR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31182584 20661446 23493285 11146632
RIPK1 TAB2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CDK9 HSP71 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10617616 27684187 23455922 26209609
CRK ATX1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23275563 32814053 16713569
NEMO TAB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23986494 17626013 21988832
CFTR HSP7C â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11146634 16857740 17110338 10666020 23990462 29924966 26618866 21697503 15611333 17272822 10982807 10075921
CFTR GRP78 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22038833 29924966 26618866 17110338
NEMO M3K7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34535633 23986494 21606198 17363973 30404796 19531477 33139544 32731169
SYUA HSP7C â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21832061 31980649 22776201 17893145 22843682
TAB2 BAG2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TF65 BAG2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
M3K14 BAG2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
EGFR ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
EGFR STIP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
CHIP HSF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16293251 14532117 23344957
CRK SHC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8035825 9837978 9461587 9617486 19380743 10464310 23397142
TAB2 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TAB2 HS90A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 19875381
RIPK1 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TAB1 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TAB1 HS90A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 19875381
CSN5 NFKB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 21988832
CFTR HSP72 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31324722 17110338
F10A1 BAG1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11741305
BAG1 CHIP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25036637 20675402 26330542 11676916 15538384 16207813
ERBB3 HSP7C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31980649 24189400
CADH1 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16212417 25468996
GRP78 STIP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
TF65 GRP78 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25331947 14743216
M3K7 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
M3K14 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
HS90B HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 16263121
HSP71 ATX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25959826 16713569
M3K7 M3K5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10921914 22167179
HSP72 BAG4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 25036637
BAG4 HSP76 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 33957083
BAG4 HS71L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 25036637
PRKN2 TOM70 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 30629163 23068103 24149440 23503661 24244333 25591737
TF65 HSP7C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24175631 14743216
M3K14 HSP7C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
M3K14 HSP76 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
F10A1 HS90A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 22504172 9452498 10642522 19875381
CHIP HS71L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25036637 33957083
HSP71 APEX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 16713569 20808282 10629618 11133992
BAG3 CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 31500722 25036637 26496610
BAG3 HSF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27173435 23824909 25036637
BAG1 BCL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9305631 7834747
EGFR GRP78 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12471035 24189400 23956138 28065597 15657067
HSF1 HPBP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27173435 33961781 25036637 28514442
ANDR KDM1A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20228790 27085459 33640491 28611094 34585037
CUL4A HS90A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939624 21145461 12481031
RIPK1 M3K7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16543241 21606198 24434549 18570872
TAB1 HSP7C â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 14743216 33961781
HSP71 FAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 28443643 23414517
BRAF HSP7C â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27684187 17979178 31980649
BRAF GRP78 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27034005 27684187 17979178 31980649
BRAF HS90B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939624 27684187 17979178 31980649
ANDR CHIP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27835608 16725394 21157430 30446660 27903893 15107424 29249800 19706771 20661446
GRP78 HSP7C â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25864199 26496610 27684187 22939629 26344197
HSP71 TF65 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24175631 14743216 33961781
M3K14 M3K7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10807933 10094049
CHIP HSP72 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 25036637 33957083 24981860
CHIP BAG2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33987175 16169850 25036637 33961781 24981860 16207813
BAG5 HSP7C â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 27684187 24510904 29568061 32850835
CDK9 HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 25036637 22939624 33961781 20305087 26186194 27684187 23455922
FANCC HSP71 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 11500375 14499622 12397061
HS90A LCK â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8043579 16888650 31980649 22939624
RIPK1 HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22939624 14743216 16968706 10744744
MSRE HSP71 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11785981 16713569
M3K5 HSP71 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12391142 16713569
HSP71 GCR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24949977 12093808
NEMO HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 16189514 11864612 26496610 33961781 19875381
HSP7C EDRF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 25036637 29568061
TOM70 HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20628368 33990585 12526792
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDK9 HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 17643375 22939624 33961781 26186194 27684187 23455922
EGFR SYUA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR NEMO â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR TAB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 25402006 18271526
EGFR GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
HSF1 HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 1628823 9499401 9699716 33961781 21784850
CSN5 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 28514442 22474075 18606781 18850735 23357576 22956996 12732143 27029275 26976604 33961781 26186194 19615732 16964240 25349427 21145461 19295130 32047038
NFKB1 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8290595 7823959 16713569 16380507
BAG1 GCR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23493285 16189514 10477749 9603979 11101523
NEMO HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 16189514 11877453 16713569
HS71L HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 33957083
HSP71 HSP76 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22863883 22939629 33957083
NEMO HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 33961781 26496610 24618592
BAG4 HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 29568061 11909948 25036637
PRKN2 HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32929329 12150907 14532270 32814053 24244333
HPBP1 HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 25416956 25036637 16713569 25864199 33961781 26186194 16169070 29568061 9830037 15215316
HS90B HSP7C â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25864199 29930177 26344197
HSP7C DJC13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 29568061 26344197
HS90A M3K14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 31980649 22939624 17563756 32707033 30833792
M3K14 HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939624 14743216 32707033 31980649
HSP72 HPBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 25416956 16713569 33961781 33957083
CHIP HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32600329 25036637 32401531 20618441 16293251 32041778
TAB1 TAB2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
BAG2 HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 18457437 9873016 33961781 28042827 30021884
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
CADH1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 31980649 24189400 24658140 25402006 25468996 10969083
CHIP EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33775711 20029029 31980649 24658140 25402006 24722501 27475501
ERBB3 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21278786 24189400 27756321 18803307 17148612 25315821 22439932 10527633 23436906 23866081 10572067
EGFR CRK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16729043 9642287 31980649 10595738 22973453 24658140 11956190 16273093 9617486 25402006 12198159 8875975 9480911
EGFR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32669362 20029029 31980649 16849543 12471035 23956138 16024644 24189400 24658140 12006493 25402006
EGFR HSP7C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 24189400 23956138 24658140 28065597 25402006 15657067
EGFR HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 12471035 23956138 24189400 24658140 22939624 25402006 15657067
EGFR HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 25241761 31980649 24189400 24658140 25402006 15657067
HSP7C HSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 7639722 33961781 16293251
HS90A HSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12621024 11583998 26517842 22367781 9222609 16278218 20885985 18599869
TAB1 RBX1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
SHC1 ERBB3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9019162 9756944 24189400 22973453 24658140 16273093 16729043 11546794 8665853 9694850
TAB1 TAB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14670075 14743216 10882101 17626013 21988832 18021073 19393267 27880917 19675569 12242293 16845370 32410369 33961781 25260751 21903422
RIPK1 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 10755617 17702576 26740240 21606198 14653779 16603398 16543241 21113135 16547522 26865630 10980203 23746843 30561431 11262391 32024692 19373245 18029035 31502302 21458669 10880512 18212736 22099304 28249776 21383699 26802121 23104095 27929056
ERBB3 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
NFKB1 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 27609421 15043934 35140242 25609649
BAG1 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14517289 11278763 9565586 16713569
ANDR HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 16713569 21157430 32206096 27903893 17974989 1540595 26342197 26196320 25500540 19706771 19805354 17353003 1525041
STIP1 HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12161444 33957083 11413142 23414517 10786835 26344197
PRKN2 HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12150907 24244333 32929329
F10A1 HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 8887650 23414517 33957083
HS90A HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27353360 24949977 11413142 12093808 16263121 21360678 12853476 19875381
HSP71 HPBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 26264872 15694338 33961781 9830037 33957083
HSP71 SYUA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21985244 31980649 19875982
HSP71 CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25036637 32401531 10330192 12150907 16275660 33961781 20618441 28042827 27787517 26010904 22939629 23904609 23271055 33957083
M3K14 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 16189514 31980649 33961781 32707033 9927690 30833792
HSP7C CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26232501 27709416 27684187 15215316 25684577 21454478 25036637 16554822 21911421 20618441 23865999 11146634 29568061 15538384 25864199 26264872 28396517 16275660 18988734 16293251 11557750 26010904 27708256 17178836 27283392 15198682 25258038 29317501 10330192 23990462 33961781 16207813
HSP7C HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27708256 16189514 25864199 22504172 26344197 9269769 21360678 20039095 19875381
HS90A CHIP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23344957 23256568 17317785 21454478 18818696 20661446 12574167 11146632 22824801 20618441 30911017 19913553 15538384 16307917 32600329 26330542 16275660 20704274 21325980 15001357 16293251 33571422 17324930 23904609 23999428 19875381 27353360 18784277 19196961 20146531 21360678 18292230 16207813
GCR HS90B â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 35124280 27803151
HSP76 HSP7C â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 22863883 29568061
ERBB3 SHC1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 31862538
HSP7C HSP71 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 25864199 18457437 22863883 9305631 27684187 22939629 11741305
HSP71 HSP72 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 22939629 33957083
HSP7C STIP1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 25864199 9774640 10567422 11093761 22939629 26344197
BAG4 HSP71 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32296183 25036637 16713569 11909948 34133714 11527400
BAG3 HSP71 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 23824909 16713569 10980614 30559338 9873016 26496610 19229298 11527400 33961781 21252941 33957083
HSP71 AIFM1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11533664 12930708 16713569 29568061
M3K7 HS90A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 14743216 19026643
HSP72 HSP7C â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25036637 31536960 33961781 22939629 29568061
HSP7C BAG2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25036637 18457437 22365833 9873016 33961781 30021884 27684187 26344197 29568061 16207813
HSP7C BAG3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 25416956 23824909 25036637 30559338 9873016 26496610 33961781 21233200 27684187 21423662 29568061
SHC1 EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7518560 8034616 31980649 23956138 9544989 8610109 7542744 25402006 16729043 8665853 15657067 9742218 24797263 10049786 12577067 9756944 23799367 25187647 20935677 10766863 18271526 11408594 7506413 10635327 10595738 24189400 19531499 7542991 20473329 24430869 8662998 9020193 8887653 16273093 25754235 9388490 31959764 26551075 16713569 22973453 24658140 11196191 28065597 20067773 8810340 21278788 30544639 9130710 11370743
TAB2 M3K7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19556242 34535633 31127032 22158122 16603398 16845370 21903422 19955178 19232515 14743216 33717111 10882101 18021073 26432169 31250519 22081109 30348973 20538596 24270572 32303555 24061540 20194509 32410369 28507161 11259596 17384642 19026643 14633987 12242293 27426733 27468689 32707033 25642820 24912525 14670075 8638164 20200282 17158449 12609980 22167179
NFKB1 TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20547752 8255759 27609421 29439025 16740634 21988832 24634218 14645533 11970949 35140242 15799966 25609649 15660126 21544861 29084252 14743216 8246997 34100597 22139845 17962807 9722548 2050119 22808155 20154269 21270162 17982102 24175631 25355951 23687337 11976329 15657065 8428580 20237821 12414801 10498867 22261743 16204234 16105840 14690596 11880271 33060567 8798655 16319923 21483817
HSP7C BAG1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17954934 16189514 25416956 28215707 9774640 20675402 14978028 9873016 12874020 10671488 11222862 19800331 25535373 26871637 9305631 11707401 11741305 12297498
BAG1 HSP71 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11231577 14517289 19229298 9305631 11101523 11741305
HS90A GCR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 24949977 8898375 24462205 8621522 10066374 28537252 35124280 9334248 31467278 10903152 20195357 14987994 26804907 16131566 19875381 16087666 15916966 8089152 9195923 8139547 15004035 8645634 12093808 27803151
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SHC1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
TAB1 M3K7 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 19556242 25241761 34535633 22158122 16845370 15590691 21903422 19232515 14743216 33717111 26432169 12624112 20538596 32303555 32410369 12975377 28507161 10838074 27880917 18456659 19026643 12242293 12429732 27468689 16260783 32707033 10702308 24912525 14670075 8638164 20200282 32227113 23934659 33961781 22167179
HS90B STIP1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 25036637 21170051 18285346 22939629 26344197
STIP1 HS90A â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 24949977 24462205 9452498 10642522 18285346 25036637 26496610 10786835 11877417 22729780 22504172 22315411 26804907 11413142 20704274 20159553 19875381 27353360 33961781 21235734 21170051 19996313 21360678
TF65 GCR â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 7659084 16713569 10995388 25202013 8290595
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
HSF1 BAG3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23983126 19006120 20692357
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
RBX1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
BAG1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9305631 7834747 8947043
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
NFKB1 RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
SHC1 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
ERBB3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9694850 9756944 16273093 24189400 8026468 24658140 9590694 16189514 16729043
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
TAB2 TAB1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TAB2 TAB1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
RIPK1 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15327770 16603398
RIPK1 FAF1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
RIPK1 FAF1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
NFKB1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20966071 22708120 16317091 16271621 10833420 10496926 16249517 7536741 19281832 10553096 19422386 7537851 16385502 10946302 16453001 10329958 11359843