Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XIAP TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
XIAP TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12048196
TAB2 MALT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17948050 6177522
MALT1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17948050
CYLD RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 23010170
CYLD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17981138 19131965
TRAF2 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBC TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218828 16845370
UBC CYLD â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
CYLD UBC â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
MALT1 TRAF2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15125833 19234489 16713569
VRK2 M3K7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18286207 17709393
IKKB FKBP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 21903422
FKBP5 NEMO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
EMIL1 TRAF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
I17RC TAB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F TAB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CYLD TAB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27591049 31762063
SCRN1 TAB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TAB2 MALT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17948050 25748427
IKKA RIPK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10980203 29955050
RIPK1 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 14743216
CARD8 TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
AASD1 TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SYNCI TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EMIL1 TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SCRN1 TAB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
M3K7 MALT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17948050 25748427
EMIL1 TAB3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F TAB3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CLH1 HSP71 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33957083 26496610
SYNCI NEMO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TY3H M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AASD1 M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SCRN1 M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KERA M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PCD20 M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TBL1Y M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EMIL1 M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
I17RC M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SYNCI M3K7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDC37 FKBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
HS90A STAT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12559950 16189514
TRAF6 UBC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 17703191 19820695 18239685
UBC XIAP â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CARD8 TAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RIPK1 TAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18299187 16603398 29955050 15327770
CI041 TAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RIPK1 CYLD â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17981138 21408173 33654169 22848449 28900035
TRAF2 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
TRAF2 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
CI041 TAB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TAB1 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
SMAD6 M3K7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11737269 10748100
TGFR1 M3K7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19556242 18758450 23973329
M3K7 MK08 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11865055 17709393
IKKB CLH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
M3K7 CLH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
PPM1B NEMO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 14585847
M3K3 IKKB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11429546 14743216
IKKA M3K3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
PPM1B IKKA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 14585847
CARD8 M3K7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRS6A M3K7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
M3K7 HS71L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
M3K7 M3K3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16260783 19843958
M3K7 RUVB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
CI041 M3K7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CYLD TRAF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
TRAF2 TAB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14633987 17384642 10882101 19150425
TAB3 TRAF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14633987 16189514 16713569
M3K7 UBC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16845370 19820695
IKKB HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761
M3K7 HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 14743216
CYLD RIPK1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
RIPK1 TAB2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
M3K5 TRAF6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9774977 10523862 10921914 31077413 32445435 17724081
NEMO TAB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23986494 17626013 21988832
CYLD TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27591049 12917691 23405219 28900035
M3K7 CYLD â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29291351 27591049 32410369 18332137
NEMO UBC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16874300 14743216 17363905 19373254
NEMO M3K7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34535633 23986494 21606198 17363973 30404796 19531477 33139544 32731169
PPM1B M3K7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11104763
M3K7 MP2K4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12556533 12429732
TAB2 TRAF2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HGS M3K7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11397816 16713569
M3K7 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 3031469 15764709 32229191
TAB2 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TAB2 HS90A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 19875381
RIPK1 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TRAF2 NEMO â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10980203 28249776 31502302 23007157 12867425
TAB1 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
TAB1 HS90A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 19875381
NEMO MALT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19494296 27070702 18931663 25748427 18212736 17948050
M3K7 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
M3K14 HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
HS90B HSP71 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 16263121
M3K7 M3K5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10921914 22167179
IKKA HS90B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
HS90A M3K3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 19560753
TAB1 TAB3 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
TRAF6 TGFR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18922473 18758450 26807171 24103590 25622187
M3K7 XIAP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19584092 11865055 12048196
EMIL1 TAB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
TAB3 TAB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14633987 34012913 21903422
RIPK1 M3K7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16543241 21606198 24434549 18570872
M3K14 M3K7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10807933 10094049
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MALT1 TRAF6 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
M3K7 FKBP5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 14743216 33961781
FKBP5 IKKA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 33961781 25036637
TRAF2 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 16189514 16260598 21782231 16713569 25416956 9500555 33961781 21516116 21903422
TAB1 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10882101 30782845 10094049 11518704 19112497
M3K14 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 25241761 9275204 10921914 16286467 11278268
TRAF6 XIAP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 25241761 22493164 12048196
TAB1 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RIPK1 HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22939624 14743216 16968706 10744744
NLK M3K7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 20194509 15764709
M3K5 HSP71 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12391142 16713569
NEMO HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 16189514 11864612 26496610 33961781 19875381
IKKB HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 19786027 11864612
IKKA HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 11864612 22384180 33961781 19875381
PELI3 M3K7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12874243 15917247 18326498
TAB3 UBC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
M3K14 CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 25036637 31980649 32707033 30833792
TAB3 TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 27497262 12496252 15327770 27009840 14633987
PELI3 TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18326498 25027698 12874243 15917247 23042151
MALT1 TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19234489 25569716 15125833 22528498 29953499 23264041 17948050
NEMO TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20932475 28249776 23986494 18617513 27695001 30254148 18180283 15125833 25400026 28214532 25548215 30404796 30913450 17728323 17135271 24270048 27929056 20529958
TRAF6 M3K3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14661019 25241761 19843958 19903815
TAB1 XIAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9878061 28414080 11865055 12048196 23818254 33961781 27107012
TRAF2 M3K7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32024699 14743216 26299341 17384642 14633987
TAB3 TAB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14670075 18021073 27880917 33961781 21903422
CYLD NEMO â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15341735 21988832 16627981 31366726 12917690 26802121 12917691 22990857 12917689 30561431
HS90A TGFR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21465483 18591668 22848678
NEMO HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 16189514 11877453 16713569
HS71L HSP71 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 33957083
JIP1 M3K7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16840345 18286207 17709393
MP2K6 M3K5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15866172 16142216 20213747 11689443 25098452 12820963
M3K5 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17700517 15023544 33961781 28514442
NEMO HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 33961781 26496610 24618592
M3K7 IKKB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34535633 31127032 10022904 10779355 18316610 27387502 17363905 24270572 17363973 32410369 27693634 10807933 18456659 26334375 10195894 9689078 21331078 33895773 20932476 11460167 25946971
M3K7 IKKA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16893890 25241761 20200282 33895773 34535633 10094049 10187861 9742107
PPP6 M3K7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079228 19955178
1433F M3K3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 14743216 32707033 33961781
HS90A M3K14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 31980649 22939624 17563756 32707033 30833792
M3K14 HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939624 14743216 32707033 31980649
TAB1 TAB2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDC37 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 11864612 25036637 24618592 24189400 26496610 33961781
CDC37 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 25036637 11864612 24189400 33961781 32707033 21903422
CDC37 IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 25036637 11864612 26496610 33961781 21903422
FKBP5 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 20661446 25036637 9001212 12538866 22863883 10642522 21235734 21170051 21360678 29079741 23999428 28363942 19875381
FKBP5 HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30382094 25036637 21170051
HGS UBC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12230472 12207904 11916981 12750381
TAB2 TRAF6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11259596 24735611 10882101 12496252 21988832 17720800 18299187 15327770 19675569 18180283 11518704 14633987 12242293 24061540 22924441 19112497 12609980
M3K7 TRAF6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31127032 22924441 28024152 10921914 27249171 19232515 10882101 16543409 19675569 24434549 10094049 33768585 18758450 19521662 11259596 22851693 19843958 12496252 11518704 14633987 12242293 21822258 19112497 27501752 19820695 16517750 22643835 26038599 31885808 25963657 12609980 31404116
TAB1 TAB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14670075 14743216 10882101 17626013 21988832 18021073 19393267 27880917 19675569 12242293 16845370 32410369 33961781 25260751 21903422
RIPK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 24735611 23972990 16603398 8612133 32296183 16291755 11181075 19815541 24434549 30561431 21810480 11479302 31502302 27768232 20577214 25716317 21282461 25882049 8702708 9020361 16713569 29352166 23007157
RIPK1 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 10755617 17702576 26740240 21606198 14653779 16603398 16543241 21113135 16547522 26865630 10980203 23746843 30561431 11262391 32024692 19373245 18029035 31502302 21458669 10880512 18212736 22099304 28249776 21383699 26802121 23104095 27929056
M3K5 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9774977 18776134 19805025 16713569 10523862 16636664 17015619 25098452 32445435 15310755 29644863 17724081
IKKB TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32024699 20449947 21782231 16713569 25241761 27387502 19150425 23007157 11359906 18362886
M3K14 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9020361 15084608 16189514 23543740 16713569 20184394 25416956 31980649 9275204 25246529 20348096 20385093 11278268
TRAF2 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20449947 25241761 16713569 23007157 19150425 11359906 9244310
TAB1 MALT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17158449 15327770 10882101
TAB3 MALT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17158449 15327770 10882101
M3K7 TAB3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34535633 31127032 21903422 32229191 19232515 14743216 33717111 18021073 27497262 22081109 30348973 32410369 28507161 17384642 14633987 32707033 24912525 14670075 27009840
HS90A HSP71 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27353360 24949977 11413142 12093808 16263121 21360678 12853476 19875381
M3K14 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 16189514 31980649 33961781 32707033 9927690 30833792
NEMO IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23986494 20211142 16611882 20098747 15802604 30913450 16547522 14743216 18450452 10980203 19666608 23131831 21455180 16906147 15184390 24469399 19820708 18462684 31145594 15749833 28249776 24618592 10968790 19422324 30500824 23104095 16938294 31932854 18949366 20167598 16603398 25286246 18583959 24266532 22605335 27426725 26500060 19706536 19365808 18037881 20932476 30404796 16319058 9751060 23506214 25979343 17363973 25400026 22990857 12657630 30561431 12459277 12486103 16583354 29474632 32024699 11971985 11057907 18266467 12133833 24240172 18266324 23016877 21423167 17977820 33961781 20368414 32731169 28514442 25304104 18207244 12612076 19959994 25852190 21903422 29111346 26496610 19656241 17000764 21803029 16497931 20434986 16129692 17568778 11864612 22099304 19815509 17693255 27929056
M3K14 IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 10733566 9346485 9520446 33961781 10195894 32707033 16286467 30833792 11278268
M3K14 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 15084608 25241761 32707033 31980649 10094049 9520446 20348096 15208311 33961781 17563756 9244310 16286467 30833792 11278268 10887201 16498412
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
M3K7 MP2K6 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 23825189 15590691 15764709 17363905 19675569 12624112 10094049 17363973 10838074 17384642 14633987 12242293 17079228 23606331 10702308 12556533 16893890 20932476 26038599 11460167 12609980
TAB2 TRAF6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
M3K7 CDC37 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 14743216 31980649 19026643 33961781 32707033
CLH1 HGS â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28581508 16713569 21411634 16716190 11532964
MK08 JIP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15998799 16840345 16533805 12756254 33961781 18286207 9733513 16343492 11700324
MP2K4 MK08 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9661668 11279118 15998799 9162092 13130464 16533805 12788955 11062067 11707464 9808624 32707033 10713157 12391307
M3K7 HS90A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 14743216 19026643
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC37 HS90B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25036637 28215707 24189400 23428871 26496610 22939624 33961781 27339980 11036079 25486457
CDC37 HS90A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 24292678 24462205 22939624 14718169 15647277 16335536 21871133 25036637 26496610 21745565 25486457 12176997 22729780 24189400 22504172 22315411 26804907 11413142 12930845 20159553 15001580 19875381 27353360 9685350 33961781 16611982 21360678
TAB2 M3K7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19556242 34535633 31127032 22158122 16603398 16845370 21903422 19955178 19232515 14743216 33717111 10882101 18021073 26432169 31250519 22081109 30348973 20538596 24270572 32303555 24061540 20194509 32410369 28507161 11259596 17384642 19026643 14633987 12242293 27426733 27468689 32707033 25642820 24912525 14670075 8638164 20200282 17158449 12609980 22167179
NEMO IKKA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11080499 21703539 23986494 16611882 25304104 20098747 18949366 18207244 11877453 30913450 12612076 19959994 21903422 22605335 14743216 10733566 10980203 22547678 19666608 23131831 26496610 17363973 21455180 22990857 12244103 26500060 18079694 30561431 12459277 17000764 15184390 12486103 16583354 24469399 18462684 11485410 25355947 11057907 32707033 16497931 15749833 20434986 18266467 32935379 17568778 11864612 17244613 24618592 28249776 23016877 12138192 19815509 17977820 10968790 20368414 30404796 33961781 16938294 16319058 9751060 17728323 27929056 32731169
IKKA IKKB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 11080499 9914500 9346241 9346485 11585904 21784860 25852190 25748427 12210728 21903422 14743216 10733566 12244103 9346484 12486103 11971985 21575199 11057907 32707033 16286467 16129692 20434986 11864612 16713569 23016877 20932476 10968790 30500824 17693255 33961781 9751060 16319058 9721103
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
TAB2 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TAB1 M3K7 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 19556242 25241761 34535633 22158122 16845370 15590691 21903422 19232515 14743216 33717111 26432169 12624112 20538596 32303555 32410369 12975377 28507161 10838074 27880917 18456659 19026643 12242293 12429732 27468689 16260783 32707033 10702308 24912525 14670075 8638164 20200282 32227113 23934659 33961781 22167179
NLK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17563747 17145710 15764709 15004007
TRAF6 MALT1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11274345 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 TAB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 TAB3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
CYLD TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12917691 12917689 16230348 29933112 18382763
TRAF6 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 15492226 19675569 15932500 18180283 16251197 10882101 18299187 11259596 1551980 24061540 21988832 19112497 22924441 11518704 11809792 15836773 14633987 14751757 25290089 12496252 12609980 12242293 24735611 14982987 15327770 17720800
TRAF6 MALT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15125833 17948050 22528498
TRAF6 TAB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 25290089 14633987 15327770
TRAF6 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21305609 17145710 11809792 12242293 19775907 10882101 25290089 10094049 30782845
XIAP TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9878061 12048196 17560374 27107012 11865055 23818254
TAB2 TAB3 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB2 TAB1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TAB2 NLK â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
TAB2 NLK â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
TAB2 TAB3 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB2 TAB1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
RIPK1 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TAB3 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 34012913 14633987 21903422
RIPK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15327770 16603398
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TAB3 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TRAF2 TAB3 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
CYLD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12917691 23405219 17851586
TRAF2 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14743216
TAB1 NLK â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
TAB1 NLK â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
SMAD6 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11737269