HGS
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20308550
0911188107
|
MED28
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033846
16964398
|
LATS2
|
YAP1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.8
|
0.8
|
Signor
|
22658639
|
LATS1
|
YAP1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.81
|
0.81
|
Signor
|
22658639
|
RHOB
|
CD44
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
MERL
|
EMD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
26549023
|
CUL4A
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18332868
20178741
|
RN166
|
AMOT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
MERL
|
SRRM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26549023
|
MERL
|
PHLP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MERL
|
TBA1C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24366813
26549023
|
MERL
|
TSYL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
LIPA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
SPTB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
YAP1
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
27684187
25796446
26933062
30472188
24255178
24366813
|
LATS2
|
AMOL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21832154
34404733
26598551
24255178
|
CCNL2
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MERL
|
AMOL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
21481793
33058421
26549023
33961781
24981860
24366813
|
RN166
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RN166
|
AMOL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
EGFR
|
CD44
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11606076
16565089
12093135
15597342
23265944
|
MERL
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25043298
28628118
28205554
|
EGFR
|
EMD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24797263
20937808
28065597
|
LATS2
|
AMOT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24225952
24101513
24106267
24255178
30266805
|
EGFR
|
EZRI
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24658140
31980649
1382070
12560083
|
HGS
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11397816
16713569
|
PAK1
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
14580336
21481793
11719502
|
VPRBP
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17079684
17630831
20870715
18606781
30590706
31973889
17609381
25532805
21145461
19295130
30166453
33355139
16949367
|
LATS2
|
LATS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
24255178
34079125
32707033
21233212
|
MERL
|
MED28
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15467741
|
MERL
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18332868
26549023
33058421
20178741
|
MERL
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
32814053
23455924
|
AKT1
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24886428
23397142
14749719
12138087
|
AMOT
|
AMOL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16678097
32296183
24255178
|
MERL
|
AMOL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
21481793
33058421
26549023
33961781
24255178
|
EGFR
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
YAP1
|
LATS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
25283809
|
LATS2
|
YAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18640976
21041410
25670202
34404733
30865227
33368671
18413746
18565851
26578655
28205554
28754671
25751139
19797269
30472188
29183995
28628118
21832154
25796446
22863277
26598551
21041411
30266805
19919647
|
AMOT
|
LATS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
30266805
32292505
24101513
24255178
34079125
24366813
|
MERL
|
LIPA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
|
AMOT
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
MERL
|
CD44
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
19351837
28628118
12356905
24912773
28205554
17891137
|
EZRI
|
CD44
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
12032545
12370738
20711218
|
EGFR
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
12522133
25402006
|
EGFR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23477725
12953068
20308550
23153581
23602387
25588945
18508924
15212941
|
AMOT
|
YAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
30266805
23564455
24976009
24225952
25751139
31501420
32292505
29891922
30472188
24106267
24255178
24101513
32755583
24366813
19615732
22385262
|
AMOL2
|
YAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
27684187
21832154
25796446
26598551
25751139
26933062
30472188
24255178
24366813
|
YAP1
|
NHRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
10562288
|
YAP1
|
AMOL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
25751139
25796446
31501420
26933062
30472188
24255178
24366813
|
MERL
|
LATS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29183995
33368671
28628118
24012335
28205554
26045165
|
AMOT
|
AMOL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24981860
24255178
34079125
24366813
19615732
|
MERL
|
NHRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26045165
9430655
15467741
|
CUL4A
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22952844
17079684
22118460
15448697
26613412
22910413
25349427
21145461
22474075
27462452
16473935
15811626
18606781
26231201
18593899
16678110
16964240
33536335
19295130
25982117
33759138
16260596
27113764
21113133
30898011
28886238
26976604
27203177
17392787
25795299
22939629
26344197
14739464
27294876
10585395
27573245
31911655
17041588
20870715
27203182
31973889
32235678
16861906
19966799
22342275
34251884
17626091
19287380
30945288
16949367
32140073
|
DDB1
|
VPRBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21957298
25499532
26613412
30166453
17314515
18606781
28416635
24558487
19295130
30590706
24412650
17609381
27571178
25532805
16949367
28202763
27354282
20870715
25557551
19287380
33355139
26344197
|
MERL
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16713569
31467278
29997244
11779178
12444101
12444102
11285248
10861283
32814053
|
YAP1
|
LATS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18640976
27325643
32292505
27684187
27886176
21383157
18413746
33141042
26933062
24366813
31619268
28754671
30461308
27847303
25751139
29891922
17889669
30472188
28416659
25283809
24107629
22641346
18158288
25796446
22863277
20841485
24255178
21041411
34079125
30266805
|
YAP1
|
LATS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17974916
21832154
21205866
|
AKT1
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17891137
28205554
28628118
21750658
|
MERL
|
LATS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24012335
26045165
34079125
33058421
|
AMOT
|
MERL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
21481793
33058421
26549023
33961781
24981860
19615732
23414517
34079125
24366813
26045165
|
MERL
|
SPTB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11779178
9537418
11535133
|
MERL
|
VPRBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33058421
26549023
21750658
18332868
24912773
20178741
|
NHRF1
|
EZRI
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11684085
11285285
20937695
23414517
15020681
34079125
29568061
26344197
9314537
|
CUL4A
|
VPRBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
MERL
|
EZRI
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10036239
16189514
17891137
|
LATS1
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
DDB1
|
VPRBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
LATS2
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CUL4A
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
DDB1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
EGFR
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12953068
17016520
|
AKT1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11435472
14749719
24886428
14585966
23397142
9032240
12138087
|
LATS2
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
36.0
|
1.0
|
Omnipath
|
22863277
20048001
18413746
24525530
15302935
19797269
17974916
18640976
18369314
29179447
18669648
25670202
26578655
29680477
18565851
21233212
21041410
18158288
19919647
18220336
21832154
22658639
21041411
24976283
26598551
|
AMOT
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
32755583
21205866
26269582
21808241
|
AKT1
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
27979972
25360797
26804165
28273460
25751140
24101154
25751139
34052254
25362852
28114269
28793266
26265440
31239271
25601544
28474680
33630828
26119935
27144834
27425596
25531778
34206989
34465890
21945154
25195862
31792377
18640976
28775168
32015438
32523092
22234184
33536280
33622361
30600590
24362629
34155345
24658687
21060948
33162394
20153295
26668327
21730131
26549256
21666719
25605730
26039999
34226698
20823509
34516278
27033705
32064037
32271880
32513743
33990468
24812269
32053631
32929029
34058200
25772246
26364602
27765911
26678338
27979971
33552953
28171658
34129887
21376238
28416665
25998128
25109332
12535517
31988076
26933062
26598551
25373897
|
LATS1
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
22863277
24366813
35044719
20048001
18413746
17889669
15302935
21383157
23752589
17974916
18640976
22641346
23027127
20841485
18369314
29179447
18669648
24255178
18565851
21909427
21170084
25283809
29487715
18158288
29496737
18220336
22658639
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