Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IQGAP2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STK25 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CAD MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ABL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11753601 9916993
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
AURKA AJUBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15630414
PRKACA AK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AMOT WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21205866 23431053
ANAPC5 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8638126 9556553
ANAPC1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC2 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
CDC23 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR LATS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131260 20610535
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
AR F2R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 15629896
AR NF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16046619
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
AR CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10076995
AR F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15629896
AR FKBP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131019
IKBKB AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
AURKA CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
BAG5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
LONP1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDC37 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HRAS CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
CHEK2 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15862297 5217705
CPVL MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
DNAJA3 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DNAJA3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJC7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
XPO1 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
LATS2 FHL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
FNTA HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24294527 2217184
LATS2 GRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GRAP2 LATS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
YWHAG HAX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HAX1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HAX1 XPO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23164465 8401898
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90AB1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
MOB1B LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1A LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
WWTR1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21205866 18227151
LATS2 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 22658639
TP53 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17015431
MOB1A LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1B LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
TNIP3 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LONP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STUB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKDC MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SUGT1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PIH1D1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAH MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PLOD1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SEC16A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RASSF1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18566590
PPP2R1A MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
XPO1 MTA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
NF2 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NF2 TNIP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PPP1R13B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15090446 15731768
PPP1R13B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16139958
STK25 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PRKDC YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
YWHAG YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSP90AA1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 MAP3K5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
LATS2 RASF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 26578655 28205554 28628118
YWHAG DYRK1A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
DYRK1A YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 36950384
LATS2 SAV1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
LATS1 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 22658639
RASH LATS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21041410 30639242
1433G LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G WWC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G AMOL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F AMOL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F WWTR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F WWC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CTNB1 LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 34079125
LATS2 AFAD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24255178 34079125
ASPP1 LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21041411 34079125
GRAP2 APC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
LATS2 JCAD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28775168 24255178
SAV1 AMOT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30266805 24255178
STK4 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 24366813
YAP1 CPVL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26933062 24366813
HRAS RASSF1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
YWHAG MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
STK4 XPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23386615 26673895
USP9X YAP1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
STK3 MOB1B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 21808241
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
FHL3 ZYX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AURKA LIMD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
YAP1 MERL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26933062 25796446 24255178 27684187 24366813 30472188 28514442
LATS2 1433F â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
HDAC1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10958684 27684187 31130994 16204248 17412698 19166851
ASPP1 LATS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21041410 24255178 21041411
LATS2 AMOL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34404733 21832154 24255178 26598551
WWTR1 AMOT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 20972459
GRAP2 CDC23 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
TAZ LATS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33141042 22078877 24107629
SNAI1 MDM2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22128911 34040386 20385133
MOB1B MOB1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
STK4 RASSF1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
HDAC2 SNAI1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
LATS1 STK4 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ABL1 1433F â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25852190 15696159 16888623 28514442
LATS2 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24255178 24360964
CTNB1 UBR5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28689657 32914356 21118991
AJUBA SNAI1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25314079 18347060
LATS2 AMOT â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24255178 24225952 24101513 24106267 30266805
FKBP5 AURKB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 32707033
AURKB SUGT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
LATS2 CPVL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 24255178
HDAC2 FOXP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 19276356
MOB1B STK3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
LATS1 LIMD1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
AMOT NF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
LATS2 1433G â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21118956 28205554 28628118
RASF1 SAV1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21489991 17379520 24981860 20920251
LATS2 APC5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29183995 32707033 24255178
NF2 AMOT â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
LATS2 LATS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 21233212 32707033 34079125
LATS2 SNAI1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24157836 21952048
LATS2 USP9X â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29183995 32707033 24255178 28720576
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
LATS2 APC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29183995 32707033 24255178
AURKA LATS2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21822051 28205554 15147269 28628118
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
WWTR1 LATS1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22078877 21555462 29787761 20412773 27847303 26116754
MERL AMOL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 24255178 26549023 21481793 33058421
SRC RASH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30194290 12695509 30639242
M3K5 1433G â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 19935702 33961781 24985705
1433G WWTR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20936779 28514442 33961781
1433F KIF23 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 31586073 26496610 14676191 28514442 17979178
1433F AFAD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 17979178
ABL1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23950177 17318191
AMOT AMOL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16678097 32296183 24255178
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SAV1 HAX1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22570112 21567072
SUZ12 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26344197 22439931 24457600
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
YWHAG KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5217174 15324660
SIAH2 LATS2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25438054 27030211
STK3 STK4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LATS2 MOB1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
STK3 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 23431053
SIAH1 SIAH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AR STUB1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AMOTL2 YAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC1 SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDC37 IKBKB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
M3K5 LATS2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 30496488
YAP1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24976009 23245941 27173435 27684187 33643786 21376238 29789528
AMOT LATS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 32292505 24101513 24366813 30266805 34079125
CDC37 AURKB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 31586073 26186194 29568061 32707033
CDKN1A LZTS2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
EZH2 SNAI1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24903147 18519590 21685935
MOB1B LATS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16674920 19739119 24255178 24366813 18328708 28514442 34079125
STK4 MOB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 22863277
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AMOT YAP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KIF23 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
LATS1 ZYX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10831611 16713569
MERL LATS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26045165 33368671 29183995 28205554 28628118 24012335
ABL1 1433G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25852190 15696159 16888623 28514442 30021884
1433G 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 26344197 26496610 28514442 22863883 17979178
M3K5 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 17700517 15023544
YAP1 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25751139 26933062 25796446 24255178 27684187 24366813 30472188 28514442
USP9X AFAD â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9722616 10620020
APC1 CDC23 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11076961 20360068 22939629 26496610
APC5 CDC23 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20360068 22939629 26496610
AMOL2 YAP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26933062 25751139 25796446 21832154 24255178 27684187 26598551 24366813 30472188 28514442
AJUBA LATS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20303269 16413547
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
SAV1 LATS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25670202 25692647 24255178 34404733 30266805
STK3 MOB1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23972470 31941533 24255178 18362890
STK3 MOB1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 24255178 19919647
STK4 SAV1 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 16930133
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
LATS1 WWTR1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MERL LATS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26045165 24012335 33058421 34079125
AMOT MERL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26045165 33961781 32296183 24981860 19615732 26549023 21481793 33058421 24366813 23414517 34079125
RASH AFAD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10334923 30194290 10922060 8557659 10545207
RASF1 RASH â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32814053 10998413 16810318 18596699 11857081
YAP1 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 17353931 25796446 24255178 27684187 28205554 28628118 24366813 28514442
1433G KIF23 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 17353931 25658096 26496610 20451386 28514442 31586073
1433G AFAD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 15324660 17353931
RASF1 STK4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 23455922 33961781 24981860 20562859 17598981 24255178 15109305 26186194 14729613 24366813 23386615 28628118 28205554 26578655 20920251
STK3 RASF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 23455922 32296183 24981860 17598981 18347058 17379520 24255178 20086174 26186194 14729613 24366813 17889669 28628118 28205554 28514442 32707033 20920251
USP9X CTNB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27783990 14742711 26717875 34097426 10620020 31073027
APC1 APC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20360068 12956947 26344197 22939629 11076961
SRC ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11494128 12522270 11781820 17318191 17474147
ABL1 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12110584 25624478 16702947
ABL1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26603102 25219501
AR HIGD1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11867260 20610535
CDC37 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32707033 31980649 11085988
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
HSP90AA1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
HSP90AB1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
SDF4 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CTCF SUZ12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21536749 33196849 18662993
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
FNTB HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15451670 24294527 2217184
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 20714342 19703393 18451879 12920132 26344197 21258344 31980649 24981860 22939629 12493763 11102443 19686092 23752268 11297506 30737378 26949739
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YAP1 LATS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27325643 29891922 28416659 27847303 32292505 17889669 30472188 33141042 18413746 22641346 26933062 18640976 24255178 27684187 22863277 24107629 30266805 31619268 21041411 21383157 30461308 24366813 20841485 28754671 25751139 25796446 27886176 25283809 18158288 34079125
NF2 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
YAP1 LATS2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17974916 21832154 21205866
NF2 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
MTA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11099047
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
STK4 STK3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
NUP214 XPO1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
STK4 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 21808241
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
LATS2 STK4 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
MDM2 RASF1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 18566590 23038753
TP53 FHL3 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.93 PKG 28854368
LATS2 STK3 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RASSF1 STK4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RASSF1 STK3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
STK4 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
LATS2 MOB1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MOB1A STK4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHEK1 CHEK2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SRC CTNB1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23246962 11279024 22056988
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
STK3 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
LATS1 STK3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
LATS2 NF2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MOB1A STK3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
AHSA1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
ANAPC5 ANAPC7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
LATS1 MOB1A â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SAV1 STK4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LATS1 MOB1B â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
ANAPC1 ANAPC7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC5 CDC23 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SAV1 STK3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC7 CDC23 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
LATS1 YAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
LATS2 YAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ANAPC1 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
FNTA FNTB â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ANAPC1 ANAPC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
LATS1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10831611 16713569
DCAF1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24912773 21750658 20178741 26549023 18332868
PRKACA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 19651622 17081983 1359877 18767875 17322306 18691976 4092695 19664994 20068231 18707149 23429703 11986331 17206380 14991569 19664995 18669648 33771897
ABL1 YAP1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 9168117
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 AHSA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26235616 27515256 29127155 26693507
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 25361080 19788416 21199784 29449692 18955976 21051857 18280240 21435002 18701449 27807512 20841568 21214929 21945154 29179447 15459660
ABL1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26721416 27618557 24868554 21715626 30903103 22590567
ABL1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27618557 22590567
ABL1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15686624 9109492 9295282 9312071
AHSA1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
NF2 AMOT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19615732 24366813 26045165 21481793 26549023 23414517
AMOT YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 32755583 21205866 26269582 21808241
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16281084 10076995 11606392 10606230 20610535 10809237
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR NUP214 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
AR FKBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15821585 19433513 20048054 21809344 11867260 16210365 20610535 17142810
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
PRKACA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23861900 16222244 16246726 33744274 29764989 26165940 11039908 17545617 27242098 26481147 28869606 26134678 33988677 26831064 33760847 16083426 17895985
AURKA LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21118956 21788394 25482410 15147269 10673337 21822051
AURKA RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22438769 17563743 19276349
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
CHEK1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23321637 22024163 17276342
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
AURKB RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19887622 19276349
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CDK2 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20935635 25800736 29576612 23241245 32368395 29556394 17570479 27863310 26279746
CDK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765472 21965652 21907702 18983824 24242917
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
MAP3K5 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17325029 12820963
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26516160 24804719 26437226 29555944
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
PRKDC CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 77.0 1.0 Omnipath 31959038 12607004 22669845 18948271 16794575 24492479 15829965 23684611 12805407 20406977 26929199 21482692 27818175 20660628 33870196 11668173 21731742 33879618 15618221 11901158 24421316 21099343 12386164 15096610 24415760 12447382 12855706 15213307 16150728 20599567 16024600 17570479 12447371 28750002 34244606 33901880 15367709 26505995 16940182 33747205 11025670 12024051 24844881 15668230 10973490 20713355 33961649 19151762 16936775 16798742 12607003 30001349 18644861 25361978 20305300 11390408 20501833 15361851 16982735 23380594 15674326 17237275 20160490 20498628 33851958 15282313 25550082 31609975 15975956 11085506 12493754
CHEK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15862297 10710310
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
DYRK1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20696760 24901999
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
FNTB FNTA â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 15248757 12036349 32296183 11687658 24981860 15170324 15451670 26186194 12825937 28514442 16189514
SNAI1 HDAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
SNAI1 HDAC1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
SNAI1 HDAC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16810318 17145710 18596699 32814053 10998413
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
MAP3K3 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15218148 17145710 9819420 15572679 11429546 15214841 14743216 15371334 16267042 14636585 16737960 17197697 9346241
TP53 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15540784 11791186 11504717
STK3 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22195963 29970086 19962312 15688006 30038061
STK4 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15688006
LATS1 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23026745 22078877 20412773 22658639 33086783 24550007 21808241 29787761 34022224 20594350
LATS1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 22863277 24366813 35044719 20048001 18413746 17889669 15302935 21383157 23752589 17974916 18640976 22641346 23027127 20841485 18369314 29179447 18669648 24255178 18565851 21909427 21170084 25283809 29487715 18158288 29496737 18220336 22658639 35210364 27325643 19141641 21041411 25180175 27322327 27847303
STK4 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 26898830 26578655 24255178 23431053 21808241
STK3 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26898830 21832154 15688006 23431053 21808241
LATS2 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 34335956 27840647 26831822 21952048 24168186
LATS2 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 22863277 20048001 18413746 24525530 15302935 19797269 17974916 18640976 18369314 29179447 18669648 25670202 26578655 29680477 18565851 21233212 21041410 18158288 19919647 18220336 21832154 22658639 21041411 24976283 26598551
LATS2 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22658639 18227151 21808241
LATS2 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21118956 25086053
PPP5C MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17456047 11689443
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
STK3 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23972470 18362890 23431053 21808241 32513747 30038061
STK4 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24255178 23386615 23431053 21808241 18328708
STK4 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18328708 22863277 23431053 21808241
STK3 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19878874 32296183 23431053 21808241 18328708 19919647
PRKACA NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 15743831 33058421 22516197 18071304 17175165 16652148 16267393 18835652 11703924 15378014 17566081 27285107 14724586 14981079 11719502 25925953 17998937 11782491 26997273
TP53 PPP1R13B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11684014 18676979 14729977 18275817
PPP5C PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14734805
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
TP53 RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23779024 23038753 21364923
RASSF1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20562859 17145710 24366813 26186194 14729613 26578655 24255178 20920251 22683405 15109305 23386615 17598981 21808241 23455922
RASSF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17379520 24366813 26186194 14729613 22195963 24255178 20920251 21808241 21199877 19962312 20086174 32296183 17598981 29063833 18347058 17889669 23455922
SAV1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 24366813 16930133 26186194 24255178 20920251 21084559 23386615 25692647 17517604 23455922
SAV1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20562859 21988832 17379520 24366813 16930133 26186194 17145710 24255178 20920251 21084559 15688006 32296183 29063833 23455922
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368