HMMR
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001199
22110403
|
KPNA2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9497340
6547667
|
NCK1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
TPX2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001199
22110403
|
BRCA1
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221252
8955125
|
EP300
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23353771
23285190
|
AURKA
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
CDK1
|
NUMA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7769006
23921553
|
CDK1
|
TPX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25688093
29052541
|
AURKA
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
CDK2
|
TPX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25688093
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
GRB2
|
GSTM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
HNRNPU
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IKBKG
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
STAT3
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19084525
6979076
|
PIK3R1
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
AR
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12933816
|
PIK3R1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25814554
15021914
|
CRK
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
NEK7
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CDH1
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TPX2
|
CALR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TPX2
|
CDK5R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TPX2
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19357306
0900833106
|
TPX2
|
HMMR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001199
22110403
|
TPX2
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
TPX2
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TPX2
|
CDCA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12389033
|
CHUK
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
CHUK
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
CHUK
|
IKBKB
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
12799363
23430059
|
AR
|
CALR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11817565
20610535
|
ESR1
|
SIAH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18414489
16141343
|
AR
|
CDK5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23941877
20610535
|
IKBKB
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17939994
0706493104
|
HNRNPU
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
DLST
|
NAP1L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CRK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
FZR1
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
1204073
5215931
11244506
|
CDK2
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
TPX2
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17474147
32203420
|
ESR1
|
GSTM3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23576398
31527615
|
ESR1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21761334
31527615
|
HMMR
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25184681
22110403
26831064
|
MK14
|
TPX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
GSTM3
|
TPX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
HMMR
|
TPX2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15705883
22110403
|
BRCA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
EP300
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12649209
33742100
|
LMNA
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30179224
22412018
30419336
|
CRK
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8879209
9837978
|
IKBKG
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
AURKA
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22110403
14990569
26831064
|
EP300
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10205054
15653507
16713569
33531691
26504087
18782771
30110629
11923478
15735682
15649887
33742100
22116549
|
PIK3R1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
5220480
7642581
|
ESR1
|
MEN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16651450
31527615
|
ESR1
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23874500
11429412
|
TPX2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25184681
22110403
29656893
|
EP300
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
EP300
|
NAP1L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TUBG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
IKBKB
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CRK
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25241761
11418612
10962563
12878163
25814554
19380743
|
AR
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CRK
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
MDC1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21622030
19766185
15569676
12611903
17525332
12607005
29656893
|
P85A
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23065768
16713569
17043237
11689445
11029009
|
AURKB
|
CDCA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
ESR1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
1244506
11782371
15674350
29367421
27977889
17392432
16860316
10334989
16260778
11244506
16061635
12400015
17505062
20060929
25499220
16713569
31527615
11493692
|
EP300
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21102443
19887647
10655477
11782371
16713569
21212407
22787115
|
CDK2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
16713569
10373534
9244350
8764100
|
CDK2
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26186194
10330164
23455922
|
EP300
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
11782371
12738788
25728767
11867769
12479814
23065768
15308690
20388208
14761960
22227247
8799122
20348541
23403292
12714702
11581164
16713569
19838210
18765668
16645043
30418174
12574227
|
EP300
|
KPNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10801418
15342649
|
IKBKG
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
8209688
506093200
16126728
|
AR
|
PIK3R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22740037
12063252
20610535
|
STAT3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21546410
|
TPX2
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
20360068
14600264
18773538
14580337
33961781
12177045
26186194
19357306
26831064
22110403
|
CDK5
|
TPX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
31272499
|
AR
|
CDK6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
15790678
|
AURKB
|
HDAC9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22865920
|
AR
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18794357
20610535
|
ESR1
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21761347
21761334
18497064
|
AURKA
|
KIF11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15630414
17939994
|
AR
|
HMMR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
18174258
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
CHUK
|
MAP3K14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
GRB2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
CDK2
|
FZR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
KPNB1
|
KPNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
17596301
|
CDK5R1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
23543736
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
MAP3K14
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
16498412
5218365
|
KPNA4
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.94
|
0.94
|
Signor
|
18326489
|
KPNA1
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
AURKA
|
TPX2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.96
|
0.96
|
Signor
|
26240182
|
P85A
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25416956
9174058
11418612
21706016
7544353
18346204
7737969
9886492
16219545
19380743
7642581
7759531
16713569
8621719
7642542
9541596
8647120
32814053
20936779
|
CRK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8810325
10962563
8662907
19380743
10970810
|
IKBKG
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219009
16938294
|
IKBKB
|
IKBKG
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.98
|
0.98
|
mint
|
8209688
16126728
506093200
|
AURKA
|
TPX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
KPNA2
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
KPNB1
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CHUK
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
AURKA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
BRCA1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
BRCA1
|
AURKA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11877377
15459660
19075565
19793801
20011137
20029420
21060331
21337561
|
MDC1
|
BRCA1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
12607003
15279786
15459660
17303408
17660363
18001824
18006705
18087291
18583988
18590585
18678890
7575488
9407949
|
CDK2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8764100
10373534
10550055
19683496
16713569
26719576
15212693
|
AURKA
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
22864622
22340593
18026198
24775809
14990569
|
MDC1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18087291
17525332
12607005
|
CDK1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9244350
21706030
10550055
17570479
19683496
16713569
26745677
32193285
26719576
|
BRCA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11085509
16713569
11016951
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
LMNA
|
CDK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
22986494
2188731
2344612
2188730
|
CDK1
|
GOLGA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
Reactome
|
15678101
7737117
11238451
11306556
18167358
1902553
9150144
10679020
9753325
11285137
|
CDK1
|
NUMA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
26832443
24241204
23921553
24109598
|
CDK1
|
KIF11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
26615533
19007248
16565220
19691289
19001501
28487562
19664994
20068231
16455663
25660025
19690332
8548803
21522128
19413330
9235942
20068230
|
CDK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
26573794
12569365
22275373
25704883
17043241
23321516
9725910
24480624
21799006
24424504
28062857
21820033
25950519
28415597
27450452
25691442
21782001
|
CDK1
|
LMNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
19007248
16565220
20166139
17081983
18767875
20393185
23870088
17137347
19413330
18187866
19194518
30190500
19664995
19415658
15302935
7925482
16083285
95010153
24741066
20068231
18452278
18077418
17570479
18491316
18669648
32071079
23427156
2344612
18691976
26922519
17287340
18815303
20068230
19651622
20058876
19691289
17924679
22367880
19165338
19664994
18707149
21389115
16964243
18212344
24556839
|
CDK1
|
GOLGA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
19007248
19691289
18691976
9753325
20068231
10769027
16964243
18669648
|
CDK2
|
FZR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10323868
10375532
16582612
12730199
|
CDK2
|
FZR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
11598127
15577895
9736735
12560341
15558010
20068231
10548110
16123593
15840442
18669648
|
CDK2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10428798
22431515
23390529
17570479
23770852
|
DOT1L
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12123582
18022353
|
EP300
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11971970
10779504
24480624
17011549
16713569
|
EP300
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18782771
15509516
8756628
10205054
7530500
15653507
15735682
19506034
16285960
16713569
11322950
7499365
15649887
9590694
|
EP300
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21875947
19270680
19158375
20587414
|
GRB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
GRB2
|
NCK1
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
GRB2
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
PIK3R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
IKBKG
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
IKBKG
|
CHUK
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
MAP3K14
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16189514
9927690
14743216
|
IKBKG
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
150.0
|
1.0
|
Omnipath
|
17145710
16938294
20932476
35339487
18266324
16260493
27929056
25979343
19666608
26496610
12133833
12192055
9751060
21423167
19706536
15836773
17561400
22099304
23986494
19959994
15327770
25400026
24266532
18450452
12657630
20434986
11583588
20200955
20300203
21903422
22990857
14743216
20167598
20098747
16126728
19656241
25852190
16906147
10195894
17000764
18329793
16186825
16547522
16611882
18037881
10968790
16497931
25286246
18462684
18207244
16603398
17965022
17977820
24240172
17568778
15084594
16129692
23506214
16319058
23123196
18949366
15218526
22605335
20368414
10837071
19820708
10980203
23131831
17363973
15214841
25304104
16493424
15184390
15691841
11864612
15802604
17693255
21455180
11865184
20211142
11971985
16970925
24469399
24618592
12486103
11057907
24369075
19365808
18583959
27426725
12612076
19422324
10094049
23109003
21803029
12459277
21640763
16285893
18266467
12709429
15620648
17072322
19815509
15749833
|
IKBKG
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17145710
17485448
16938294
11865184
11877453
16970925
22435554
17244613
17568778
17363905
16818229
15084594
15485931
24369075
20300203
21217011
12799363
23180781
14743216
16319058
21703539
19666608
20098747
12612076
16126728
15218526
23430059
9751060
20138012
18716620
20368414
10837071
25355947
15836773
23109003
20531300
17702576
17363973
15214841
12459277
17561400
21640763
16285893
28462531
12709429
10968790
15199157
26192618
12133805
16497931
11864612
17693255
17072322
11340079
|
KPNA1
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11032817
26491019
10523667
26496610
9922449
9102465
17596301
|
MEN1
|
CDH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19737400
9694656
10473551
19079338
|
CRK
|
PIK3R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
NCK1
|
PIK3R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
STAT3
|
PIK3R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11733515
24218138
23963458
15793565
16293640
|
ESR1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11029009
11689445
16169518
23065768
16713569
|
CRK
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10962563
35044719
25241761
19380743
12878163
25814554
11418612
|
PIK3R1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10962563
35044719
25241761
19380743
12878163
25814554
11418612
|
SIRT6
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18337721
16439206
19408108
|
STAT3
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CDK5
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
MAP3K14
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17543278
20685151
|
CDK5
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25038288
16651438
19156541
12763138
28114390
16879821
23941877
15096606
26198700
|
AURKA
|
TPX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
15630414
14600264
18773538
26186194
17145710
20360068
14580337
26240182
19357306
12177045
22110403
|
RAN
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10400640
16713569
18565325
|
RAN
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
10779340
8909533
11024021
9214382
20658144
8576188
26496610
9102465
9135132
10944119
10037787
9045717
|
AURKB
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
11278789
19007248
17938195
10464286
16457588
12234980
12082625
21282660
15249581
10949293
15108802
16185088
14583461
12588998
15681610
17924679
16222246
15684425
12560483
11856369
|
MAP3K14
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
69.0
|
1.0
|
Omnipath
|
17145710
11278268
16498412
30833792
23915189
9346485
11520989
10072079
17563756
18515365
10887201
16223731
12556537
16286467
14743216
9244310
20348096
10094049
15140882
15208311
20685151
25241761
9742107
10229185
9520446
15084608
15994789
10713178
9819420
17150968
11239468
16691505
26948423
20651737
9020361
|
CHUK
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
9346484
24911653
20932476
28514442
11971985
16970925
12210728
9346485
17965022
16713569
12486103
9891086
15456791
11057907
20434986
16129692
16260493
21903422
21724995
16286467
14743216
16319058
18949366
10779355
25748427
25852190
12244103
11585904
9751060
15218526
10094049
10837071
9914500
21575199
9721103
25241761
10195894
9689078
15214841
21784860
17561400
21640763
16285893
10733566
16186825
16493424
10022904
12709429
12351658
10968790
12547194
15691841
15620648
15327770
11864612
11460167
14636585
17693255
17072322
9346241
|
CALR
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
8107809
16713569
|
ESR1
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12726856
14500345
17893710
19383788
19593637
20101232
|
CDK5
|
CDK5R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
11583627
23602568
15689152
11389014
17036052
25076872
21220307
15890360
16189514
23979715
26186194
17591690
17762160
14521924
20133653
22654103
28637746
12223541
23543736
18326489
28077789
17121855
|
CDK5
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
27917404
22014572
22275373
27902483
25982277
17043241
33932081
33038264
33974920
32846021
25851605
21799006
24424504
29423094
30414425
25691442
7565807
33994848
|
AURKA
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
14583461
15108802
17938195
15249581
12234980
12588998
12082625
|
MAP3K14
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17145710
11278268
10195894
9520446
14743216
9689078
9346485
16285893
10733566
10779355
10072079
11460167
10022904
10713178
|
ESR1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8299561
11000528
22391641
|
AR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12389206
11032808
16713569
11000528
18988627
|