Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEK7 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HNRNPU MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB2B MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MYBL2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 17975021
AR CALR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11817565 20610535
AR CDK5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23941877 20610535
AR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12933816
INCENP AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19357306 0900833106
CHUK AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
IKBKG AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
IKBKB AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
AURKA CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
BIRC5 AURKA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
INCENP AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16824953 19357306
AURKA INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16824953 19357306
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
RACGAP1 AURKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
EP300 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20660371 19102934
STAT3 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393476
NCK1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KPNA2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9497340 6547667
BRCA1 KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221252 8955125
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
TPX2 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHAF1A CCNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CDK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
NUSAP1 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12963707
TPX2 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12389033
CDH1 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 NUMA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7769006 23921553
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
MYBL2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15510213
CDK1 TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25688093 29052541
CHAF1A CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CDK2 TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25688093
TPX2 CDK5R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHAF1A PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CHAF1A NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CRK TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TPX2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLST NAP1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
ESR1 SIAH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 16141343
GRB2 TUBA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RACGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 GSTM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TPX2 HMMR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001199 22110403
HNRNPU IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB2B IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STAT3 KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19084525 6979076
TPX2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25814554 15021914
TPX2 TUBB2B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TPX2 TUBA1B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
FZR1 TPX2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
MDC1 LMNA â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
INCENP KIF22 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDCA5 TPX2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TPX2 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17474147 32203420
ESR1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21761334
BRCA1 CENPF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
BRCA1 KIFC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
RAN CDCA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDK2 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
ESR1 GSTM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23576398
CDCA8 KIF22 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDCA8 INCENP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
KIF2C TUBB2B â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
MK14 TPX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MK14 KIF22 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK1 BIRC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11861764 17681274
HMMR BRCA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22110403 25184681 26831064
CCNA2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GSTM3 TPX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HMMR TPX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15705883 22110403
CDCA5 INCENP â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BRCA1 CDK2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
LMNA MDC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30179224 30419336 22412018
AURKB CDCA8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
BRCA1 TOP2A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25184681 15965487
CRK NCK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9837978 8879209
MDC1 TOPBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
IKBKG MAP3K14 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
BRCA1 CLSPN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15096610 22863316 16713569
AURKA BRCA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22110403 26831064 14990569
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
INCENP TPX2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HJURP MIS18A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CCNA2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9244350 25091198 10373534 16713569
TPX2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22110403 25184681 29656893
CDK5 CCNA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 33961781
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 NAP1L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TUBG1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
KIF11 TUBB2B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IKBKB MAP3K14 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MIS18A MIS18BP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CRK P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 10962563 12878163 11418612 25814554 19380743
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ZWINT CASC5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20360068 15824131 24981860 26496610 26186194 21199919 28514442 17981135
P85A ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17043237 23065768 11689445 11029009 16713569
INCENP BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5219326 17099693
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
CDK1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 33961781 33422522 17679094 25852190 26496610 24302728 19483727 12853968 26186194 21308745 8463339 28514442 9053846 23602568 32707033
MDC1 TOPBP1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
CASC5 ZWINT â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
AURKB ZWINT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775627
AR HMMR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 18174258
AR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18794357 20610535
AR PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22740037 12063252 20610535
AR CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 15790678
TPX2 AURKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20360068 19357306 12177045 14580337 18773538 22110403 14600264 26186194 28514442 26831064
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
AURKA KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15630414 17939994
AURKB HDAC9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22865920
CDK2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31270457 8764100 16713569 9244350 10373534
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CDK5 TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31272499
CENPU TUBB2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EP300 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10801418 15342649
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
KIF11 TUBA1B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CHUK MAP3K14 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
CDK2 FZR1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
KPNB1 KPNA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17596301
TUBA1B TUBB2B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
AURKA INCENP â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CDK5R1 CDK5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 23543736
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MAP3K14 CHUK â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 16498412 5218365
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
KPNA4 KPNB1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CDK5 CDK5R1 â—¼   PHOSPHORYLATION ✅ - 0.94 0.94 Signor 18326489
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
KPNA1 KPNB1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
AURKA TPX2 â—¼   PHOSPHORYLATION ✅ + 0.96 0.96 Signor 26240182
P85A GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7544353 8621719 18346204 7642581 16219545 32814053 7642542 20936779 16713569 19380743 21706016 7759531 8647120 25416956 9541596 9174058 11418612 7737969 9886492
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
AURKA TPX2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
KPNA2 KPNB1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDK5 CDK5R1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
KPNB1 RAN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MAP3K14 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16189514 9927690 14743216
MAP3K14 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17145710 11278268 10195894 9520446 14743216 9689078 9346485 16285893 10733566 10779355 10072079 11460167 10022904 10713178
MAP3K14 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17543278 20685151
MAP3K14 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 17145710 11278268 16498412 30833792 23915189 9346485 11520989 10072079 17563756 18515365 10887201 16223731 12556537 16286467 14743216 9244310 20348096 10094049 15140882 15208311 20685151 25241761 9742107 10229185 9520446 15084608 15994789 10713178 9819420 17150968 11239468 16691505 26948423 20651737 9020361
CLSPN TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
CLSPN TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
AURKA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14583461 15108802 17938195 15249581 12234980 12588998 12082625
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
RAN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10400640 16713569 18565325
CALR AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8107809 16713569
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
CDK5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 27917404 22014572 22275373 27902483 25982277 17043241 33932081 33038264 33974920 32846021 25851605 21799006 24424504 29423094 30414425 25691442 7565807 33994848
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
AURKA TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15630414 14600264 18773538 26186194 17145710 20360068 14580337 26240182 19357306 12177045 22110403
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20458174
AURKB KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15630414 26148251 14972678 14960279 17567953 19632184 15064354
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
AURKB RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15630414 14744859 19007248 17178910 19555392 18201571 17287340 12689593 15108802 18669648
BIRC5 INCENP â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 INCENP â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
CDK1 BIRC5 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11069302 12124778 12792650 14551205 15279786 15917306 17303408 17466630 17660363 18414028 18590585 19016842 19081073 19586613 19652693 7575488
STAT3 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19880237 26512963 15184887 15469392 16651438 18242580 16397018 21344490 20826784 24431073 15077160 12393476 19284568 17880940 17533050 17932422 22984561
CDK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 16565220 24281185 18676872 11149963 12529428 24478433 19287963 18936249 18949405 16170024 20068231 28536639 16189514 33710603 20462440 29371939 18691976 15894279 12517802 11861764 11069302 33211707 28392503 21765467 23433354 18931693 15735703 34034636 25468890 26918045 32373497
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
CDK2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8764100 10373534 10550055 19683496 16713569 26719576 15212693
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
MEN1 CDH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 GOLGA2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 15678101 7737117 11238451 11306556 18167358 1902553 9150144 10679020 9753325 11285137
CDK1 NUSAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22101338
CDK1 KIF22 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12727876 27550518
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 GOLGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 19007248 19691289 18691976 9753325 20068231 10769027 16964243 18669648
CDK1 KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26615533 19007248 16565220 19691289 19001501 28487562 19664994 20068231 16455663 25660025 19690332 8548803 21522128 19413330 9235942 20068230
CDK1 INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26460953 20427271 25798441 28314740 29971233 19303298 21149564 26528436 20633640 16378098
CDK1 NUMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 26832443 24241204 23921553 24109598
CDK1 CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19641375 19369249
CDK1 KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20368358 29230353
CDK2 FZR1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 10375532 16582612 12730199
MYBL2 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9840932 20857481 8816442 15922873
CDK2 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11598127 15577895 9736735 12560341 15558010 20068231 10548110 16123593 15840442 18669648
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 NPAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10995387
CDK2 MYBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9840932 17081983 10095772 11264176 20068231 10593981 17570479 32979888 15302935
STAT3 CDK5 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
STAT3 CDK5 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
CDK5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25038288 16651438 19156541 12763138 28114390 16879821 23941877 15096606 26198700
CDK5 CDK5R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11583627 23602568 15689152 11389014 17036052 25076872 21220307 15890360 16189514 23979715 26186194 17591690 17762160 14521924 20133653 22654103 28637746 12223541 23543736 18326489 28077789 17121855
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
ESR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11029009 11689445 16169518 23065768 16713569
GRB2 NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
KPNA1 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11032817 26491019 10523667 26496610 9922449 9102465 17596301
RAN KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 8909533 11024021 9214382 20658144 8576188 26496610 9102465 9135132 10944119 10037787 9045717
NCK1 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
STAT3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 24218138 23963458 15793565 16293640
MDC1 AFAP1 â—¼   KO_UP_REGULATES ✅ + 1.16 1.16 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368