Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CSK PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053785 5219245
LIMK2 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053785 5219245
PLCB3 PLCB1 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
YWHAG TIAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TIAM1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053785 5219245
NECTIN3 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 12515806
NECTIN1 NECTIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215384 12011057
NECTIN4 NECTIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215384 12011057
PALS1 PATJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215229 11927608
PALS1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARD6A PATJ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
PARD3 PATJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17235357
FGFR1 AMOTL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21937427
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC42 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10934474
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CTNNA1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
CTNNA1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23949920 23431053
CTNNB1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
SMAD7 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15684397 1568439
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
DCAF7 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
DCAF7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DYNLL1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
PRKCI F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12953056 11447115
PARD6G F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12953056 11447115
PARD6B F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12953056 11447115
PRKCZ F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
PARD6A F11R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12953056 11447115
HSPD1 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA5 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPA8 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26902588 25961502
HSPA8 KPNA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPD1 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
HTT RPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25942483 1002142
SFN MAGI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
PARD3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22653443 8415349
PARD3 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PRKCI PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213720 11257119
PRKCZ PARD6A â—¼   COLOCALIZATION 2.0 0.8 intact 17057644 5219258
PRKCZ PARD6G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17057644 5219258
YWHAZ PFKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 PRKAA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
RASSF8 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TP53 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7711923 20206173
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
YWHAH STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
YWHAG STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
YWHAZ STK11 â—¼   COLOCALIZATION 2.0 0.8 intact 8329523 22575644
TP53 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18812399 8008642
YWHAZ TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAQ YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12535517 5216053
YWHAG YAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
1433G STK11 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22575644 28205554 28628118
JAM3 JAM2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11823489 21982860
PARD6A PARD3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5213720 11257119
KIF3A KIF3B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
LATS1 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 22658639
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
1433B TIAM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433Z TIAM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433T TIAM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB TIAM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
PARD3 GAB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 22883624
1433B RASF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433B LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433B GRDN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G MAGI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G GRDN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433Z RASF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PAR6G PAR6B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 14676191
PAR6G L2GL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24366813 14676191
PAR6B RASF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26186194 26496610
ESR1 1433E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
1433E PARD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17979178 34079125
1433E DCAF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 17979178
PARD3 CTNA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17057644 34079125
YAP1 CTNA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21376238 31501420
RHOB CTNA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOQ KPCI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 10934474
1433F MAGI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CTNB1 LZTS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 34079125
1433T LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433T PARD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB L2GL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB GRDN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
PARD3 AMOT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16678097 34079125
ESR1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21761334
RHOB ECT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
EPHA1 HOOK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA7 EPHA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB EPHA7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
ESR1 MARK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
MAGI1 PARD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 34079125
PARD3 MARK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 22883624
RHOB MARK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB PARD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
PNMA1 PNMA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 14676191
CDC42 TIAM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31871319 32203420
CTNB1 1433Z â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22912335 15492215 27684187 17287208
ESR1 1433Z â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 19805454
PAR6A PAR6B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 14676191
RHOJ PAR6G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319
1433F PAR6B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 14676191
1433E KPCI â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23472066 17979178 31980649
ASPP2 RASF7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24366813
RHOJ KPCI â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 26186194
RASF8 KPCI â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
1433F GRDN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 14676191
YAP1 RASF8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26933062 24255178 27684187 30472188
RASF7 PRS6A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PRS6A PARD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RHOJ CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10967094 31871319
EPHA4 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16365308 18790757
INADL PARD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17235357 34079125
LATS1 PARD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26116754 24255178 34079125
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CDH5 PARD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
INSC GPSM2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 16458856 32296183
1433G ASPP2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 15324660
KPCZ PSME3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
PP1A PARD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28330616 26116754
SMAD3 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22241478 27684187 20571128 12000714 21965288
FGFR1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 18302981 11401320
SMAD2 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20571128 23246962 27684187 12000714
SMAD1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15761153 9111321 18729074
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
YWHAB YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 8008024 17974916 1602907
RPS18 RPS3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PARD6B RHOJ â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
VHL KPCZ â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10491320 17101696 17350623
MARK2 1433E â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16306228 17979178 32707033 16968750
CTNB1 SMAD7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18593713 15684397
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
MARK2 YWHAZ â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PRKCI RHOJ â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MARK2 YWHAH â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ASPP2 CTNB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25344754 34079125
MARK2 KPCI â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 15324659
KPCI 1433F â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17979178 14676191
1433F DCAF7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17979178 14676191
VHL PRS6A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14556007 16713569
PARD3 L2GL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14676191 34079125
PARD3 GRDN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14676191 34079125
CDH5 CTNNB1 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 5219258 17057644
PARD3 DCAF7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27173435 14676191
EPHA7 EPHA3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 28514442 22036564
TP53BP2 PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5217094 15231748
YAP1 YWHAB â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
YAP1 YWHAQ â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CDC42 PARD6G â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
1433F TIAM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 17979178
YAP1 1433B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17974916 31501420 25796446 24255178 27684187 24366813 20048001 30472188 28514442 19439659
EGFR 1433B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR KPCZ â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
RHOJ PAR6B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 31871319 32296183 25416956 26186194 28514442
ASPP2 RASF8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 26496610 26186194 24366813 28514442
1433F ASPP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 17979178 26496610
YAP1 PP1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25751139 25796446 24255178 27684187 24366813
MEX3B 1433F â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 29395067 32460013 28514442 18779327
1433F RASF8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 14676191 28514442 17979178
PARD3 RASF8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 26186194 14676191 28514442 34079125
RASF7 PARD3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 34079125
EGFR NTRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
PRKCZ PARD6A â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5219258 17057644
PARD6A PRKCZ â—¼   COLOCALIZATION ✅ 0.87 0.87 mint 5219258 17057644
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PARD3 RASSF8 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AMOTL2 YAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SMAD4 SMAD7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PARD3 PARD6G â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR SFN â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PARD6B RHOQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
1433G MARK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 17353931 15324659 16959763 28514442 32707033
1433Z KPCI â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14676191 12893243
1433Z ASPP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 15161933 26496610
PAR6A L2GL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 14676191
RHOQ PAR6B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32296183 10934474 11162552
YAP1 1433E â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26933062 25751139 25796446 24255178 27684187 24366813 30472188
EGFR CTNA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 24189400 15657067
RASF8 PP1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28330616 26186194 24366813 28514442
RASF7 PP1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28330616 26186194 24366813 28514442
PARD3 1433F â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26496610 14676191 28514442 17979178
YAP1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24976009 23245941 27173435 27684187 33643786 21376238 29789528
PARD3 CTNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17057644 25241761 27684187 34079125
AMOT LATS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 32292505 24101513 24366813 30266805 34079125
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
YAP1 INADL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26933062 25796446 24255178 27684187 24366813 30472188 28514442
SMAD2 SMAD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 9111321 18729074
TP53BP2 YAP1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AMOT YAP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
LLGL1 PARD6A â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
1433G TIAM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 15324660 17353931
KPCZ 1433B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620507 16189514 21900206
RASF8 1433G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 15324660 17353931
1433G 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 26344197 26496610 28514442 22863883 17979178
1433G 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 17085597 28514442 22863883 20618440
1433G PARD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 15324660 17353931
PARD3 1433Z â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 15161933 33961781 14676191
1433F 1433Z â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 26496610 28514442 22863883 17979178 20618440
1433Z KPCZ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10620507 29491746 12893243
1433Z 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 28514442 22863883 20618440
KPCZ KPCI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24375676 31980649 25852190 11260256 28514442 32707033 29491746
PAR6G PARD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14676191 12459187 34079125
PAR6B PARD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 12459187 26186194 14676191 28514442 34079125
1433T 1433E â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31980649 20936779 21988832 17085597 28514442 17979178 20618440
1433E 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31536960 33961781 26344197 31980649 26496610 7615088 20936779 28514442 22863883 17979178 12507503
ASPP2 PARD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23606740 25344754 28400336 24366813 34079125
YAP1 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25751139 26933062 25796446 24255178 27684187 24366813 30472188 28514442
1433F 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 28514442 22863883 17979178 20618440
JAM1 PARD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11447115 17057644 12953056
1433T MARK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15161933 17353931 19011111 28514442 19553522 32707033
1433T ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33731348 31527615 11266503
PARD3 JAM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17057644 12953056
PARD3 JAM3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17057644 12953056
EGFR GAB1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
LZTS2 PRKAA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
EGFR CSK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24797263 24658140 31980649 16729043 25402006
PARD3 1433B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 17353931 24255178 14676191 28514442
YAP1 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 17353931 25796446 24255178 27684187 28205554 28628118 24366813 28514442
1433E 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 31980649 20936779 21988832 17085597 28514442 31536960 17979178 12507503
1433Z 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31536960 33961781 26344197 26496610 28205554 28628118 28514442 22863883 20618440
1433Z MARK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15161933 16306228 15324659 14676191 28514442 32707033 11257119
1433Z YAP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 15161933 33961781 29069755 25670079 24255178 27684187 28205554 28628118 30472188 26578655
1433Z EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 15389569 15657067 24658140 31980649 23956138 15225635 25402006
PAR6B KPCZ â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27107012 32296183 31980649 25852190 12887891 26186194 11260256 14676191 28514442 32707033 29491746
PAR6B KPCI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 23439680 32296183 31980649 26496610 23718855 26186194 11260256 14676191 25416956
MARK2 1433F â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19615732 16959763 14676191 28514442 19553522 17979178 32707033
EGFR CTNB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11950845 9535896 24189400 9233779
CTNB1 MAGI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27684187 10772923 34079125
YAP1 1433T â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15161933 31619268 31501420 25796446 24255178 27684187 22863277 12535517 16713569 24366813 28514442
EGFR 1433T â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 25402006 20029029 24189400
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
PPP1CA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11039908 11551964
CDH5 CTNNB1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
PRKCI ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21189248
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
PARD3 JAM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17057644 17916321
PARD3 JAM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17057644 17916321
YAP1 LATS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27325643 29891922 28416659 27847303 32292505 17889669 30472188 33141042 18413746 22641346 26933062 18640976 24255178 27684187 22863277 24107629 30266805 31619268 21041411 21383157 30461308 24366813 20841485 28754671 25751139 25796446 27886176 25283809 18158288 34079125
PRKCI LLGL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12725730
PPP1CA TP53BP2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SMAD7 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 16571110
YWHAB PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD7 SMAD4 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11279127 15265520 23784029
YAP1 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12118366 22921829 25283809
TP53BP2 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 21513714 8152471
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAZ MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 5217040 15161933
YWHAH MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 19553522 8009002 0803887
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
RASSF8 TP53BP2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PARD3 TIAM1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 15723052 23263278 17053785
L2GL1 KPCZ â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 31980649 25852190 24366813 28514442 32707033 29491746
PAR6B L2GL1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 26496610 26186194 24366813 14676191 28514442
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
PARD6G PRKCI â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
LLGL1 PRKCZ â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
F11R TJP1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PAR6G KPCI â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 30217970 31980649 11260256 14676191
KPCI L2GL1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 26344197 31980649 26496610 24366813 14676191
PARD6A PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6B PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6G PRKCZ â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MARK2 1433B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 24255178 15324659 16959763 28514442 32707033
PAR6G KPCZ â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 31980649 25852190 11260256 14676191 28514442 17057644 32707033
PARD3 KPCZ â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 31980649 12459187
LLGL1 PRKCI â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
PVRL3 PARD3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16189514 12515806
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
LLGL1 PARD6B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
1433G 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 15324660 24981860 26344197 24255178 17085597 28514442
1433F 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 26496610 24255178 28514442 17979178
1433T 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24255178 17085597 28514442 22863883 20618440
1433Z 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 26496610 24255178 28514442 31536960 20618440
1433B 1433E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 31980649 24255178 30135474 20936779 17085597 28514442 31536960 17979178 12507503
1433Z 1433E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19766566 31536960 33961781 26344197 31980649 22939629 26496610 20936779 21988832 28514442 22863883 17979178 20618440 16376338
PAR6G CDC42 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31871319 11260256 14676191
ASPP2 PP1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 21189257 27880917 15231748 32296183 28330616 23088536 22321011 26186194 16713569 24366813 28514442 21998301 29669786
KPCI CDC42 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31871319 10934474 11260256 14676191
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
SMAD7 YAP1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CDC42 PARD6A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
PARD3 PARD6A â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PAR6A CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12606577 10934474 10873802 11260256 14676191 21311754 16189514
PAR6A KPCI â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 32296183 25416956 26496610 16861740 21516116 11260256 15590654 14676191 12813044 17057644 16189514 11257119
ASPP2 YAP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 26933062 25751139 10358088 25796446 24255178 27684187 25436413 31636332 30472188 24366813 11278422 16713569
CTNB1 CTNA1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 15492215 12640114 9110993 17072306 26344197 17052462 7706414 9762469 26496610 27684187 17098867 7954478 9512503 19941816 24509793 14517306 34079125
PARD3 KPCI â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31980649 12459187 14676191 22883624 34079125
PARD3 PARD6B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PARD6B PRKCI â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
GPSM2 INSC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SFN TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PARD6A PRKCI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
SMAD1 YAP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 TP53BP2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RPS18 RPS3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
LATS1 YAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PAR6A KPCZ â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 28514442 33961781 27143478 25852190 17335965 15254234 11260256 14676191 12813044 17057644 16189514 17350623
PAR6A PARD3 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 26496610 12459187 14676191 22883624 17057644 16189514 11257119
CDC42 PAR6B â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 31871319 23439680 32296183 10934474 11162552 20936779 11260256 14676191 25416956
CDC42 PARD6B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARD3 PRKCI â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PARD3 TIAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24152735 23109003 17353362 17053785 15723052
EGFR GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 19901323 15231819 16497976 25402006 17389395 20068231 23066441 11432805 9658397 19509291 18669648 10978177 10753869 10734310 11896055 18271526 24658140 10648629 11779868 31980649 15212693 9890893 17016520
AMOT YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 32755583 21205866 26269582 21808241
AURKA PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19812038
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
ECT2 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15642749 9490022 9113980 10816584 17045588 8836113
CDC42 PARD6A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10934474 14676191 10873802 11260256 16189514 12606577
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
CDC42 PARD6B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 20936779 10934474 14676191 25416956 23439680 11260256 32296183
CDC42 PARD6G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 11260256 14676191
CDH5 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18287330 17057644 12413882 20123964 23243000 21255999
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
CTNNB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 15684397 21071413 18988627
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
PARD3 F11R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17057644 17916321 11447115
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
KIF3A KIF3B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 15852005 17641202 18497258 18820483 19081070 19565474 19718039 19853559 20215540 20375059 20643644 20956384 21602792 23031257
LATS1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 22863277 24366813 35044719 20048001 18413746 17889669 15302935 21383157 23752589 17974916 18640976 22641346 23027127 20841485 18369314 29179447 18669648 24255178 18565851 21909427 21170084 25283809 29487715 18158288 29496737 18220336 22658639 35210364 27325643 19141641 21041411 25180175 27322327 27847303
STK11 MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 14976552 19369195 28711359 22238344 17573348 17192257
PRKCZ MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15084291 15324659
MARK2 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22883624 14653998
PRKCZ PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24152735 23109003 17353362 12390250
PRKCI PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 14676191 22579248 27554858
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PRKAA2 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 14511394 15579580 8779952 14985505 14614828 11018120
STK11 PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10642499 14976552 8910387 18693249 12764152 26489410 15509864 14614828 12413941 20160076 19197243 15980064
PRKCZ STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11853558 18250273 19414597 16407220 18321849
PRKCZ YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16189514 10620507 21900206
TP53 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18281511 10101800 22427654 12640112 17404570 12447694 17361185
TP53 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20206173 17546054 18431400 21340684 20066118 20457558 20182602 11896572 6396087 14517281 21625211
SFN YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
YAP1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19914168 35044719 23431053 21685363
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD4 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10823886 15183844 10887185 19032343 10839991 16442497 10753944 10843994 15128733 10559222
YAP1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 22921829 12118366 25283809
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
TP53BP2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14985081 16139958 8875926 25502805 8016121 21513714 31515488 16713569 8668206 18275817 11839776
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501