Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GSN CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 9323209 9930654
GSN HSD17B12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN ELL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN CDS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGF2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9490736 12750158
NKAP PPIG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PIN1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
CFL2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FGF2 FGF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18552176 18757403
KMT2A MLLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7900984 18952892
ACIN1 PNN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EAF1 ELL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16006523 11418481
ATP5PF ATP5PD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AFF1 ELL3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BRD4 RTF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32416067 26344197
PPIG NKAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 33961781
ROCK2 ROCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AFF1 CCNT1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
ELL2 EAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27058417 21729782
MPPE1 SUN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MPPE1 EDEM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PPIG SRRM2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
AFF4 EAF1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CWC22 PPIG â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
AFF4 ELL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ELL3 ELL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ELL3 AFF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ELL3 CCNT1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ELL3 EAF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TULP3 RAD18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33187986 33961781
EAF1 AFF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 33961781 21729782
AFF4 EAF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 33961781 21729782
AFF4 ELL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 33961781 21729782
ELL2 AFF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26496610 21729782 24367103
EAF1 AFF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26186194 33961781 21729782
EAF1 EAF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EAF1 PLCD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EAF1 EAF2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
PIN1 RAB4A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 10888662
EAF2 ELL â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12446457 27058417 32152128
AFF4 AFF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20153263 21729782
ACTG1 CFL2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
ATP6AP1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
EAF1 ELL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194 21729782
AP3B1 AP3M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781 26344197
ELL2 AFF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 26496610 33961781 26186194 21729782 22483617
AFF1 MLLT3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AFF4 MLLT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF1 MLLT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF4 EAF2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AFF4 MLLT3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EAF1 ELL2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EAF2 ELL3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ELL ELL3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRD4 CCNT1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
EAF1 ELL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 11418481 33961781 26186194 21729782 32152128
FAM90A1 LZTS2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AFF4 ELL2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NDUFAB1 OXSM â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AFF4 ELL â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ELL3 MLLT3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AFF4 CCNT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 20153263 33961781 12065898 26186194 21729782 27684187
AFF1 CCNT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20153263 21030982 27684187 19956800 24367103
EAF1 ELL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 11418481 33961781 26186194 21729782
NKAP SRRM2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BRD4 CCNT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18039861 33567268 16109376 31753913 31239290 16109377 24360279 17690245 32416067 30554943 24367103 21555454
CAB39 STK11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19513107 25241761 26479318 14676191 15561763 20562859 31217475 31554794 33961781 15733851 25852190 32707033
MAPK1 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
ARF6 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
MAPK1 PDE4C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11030732
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
FGF2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9490736 29436393 12750158
ARF6 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
MAPK3 STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25846811
PIN1 KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKD1 PIP4K2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16563698
EAF2 ELL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16006523 12446457
CWC22 SRRM2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
NDUFAB1 NDUFC2-KCTD14 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
STK11 STRADA â—¼   PHOSPHORYLATION ✅ + 0.94 0.94 Signor 12805220
STRADA STK11 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5217549 15733851
AP3B1 AP3M1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
AFF4 CCNT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CAB39 STK11 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAP2K2 MAPK1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NDUFAB1 NDUFS8 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
NDUFA6 NDUFS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
STK11 CAB39 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15509864 18687677 19197243 19942859 20160076 20484410 23030059 8910387
CAB39 STRADA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15509864 18687677 19197243 19942859 20160076 20484410 23030059 8910387
STK11 CAB39 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15509864 18687677 19197243 19942859 20160076 20484410 23030059 8910387
CAB39 STRADA â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15509864 18687677 19197243 19942859 20160076 20484410 23030059 8910387
CASP3 GSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9323209 9930654 9671712
CASP3 ACIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10490026 21904669
CASP3 ROCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11283607
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
GSN ACTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11733011 7849017 15526166
TAOK2 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11279118 23331499 25241761 9786855 23180781 17396146 21614932 12738796 11274345 18988627 10497253 15458637 18855897
MAPK1 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
FGF19 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAP2K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 21675959 11704645 9694850 17081983 7565670 12750173 19690332 12932319 11823456 18799465 15592455 11337027 18083107 21365009 12788955 11134045 19219045 17389395 9447970 15342917 23331499 19534553 17569879 7559390 23047924 8226933 8223433 17272394 15851026 15811950 19494114 18988627 18669648 11549292 23519423 19541618 18691976 1381507 16293107 17906627 11986622 19933846 8376945 19053285 16094384 11971971 17192257 11136732 11948414 8388392 7898932 9731057 11730323 18039929 11118451 19369195 12920017 15951569 15466214 10746662
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 12054624 15547943 20080742 14967450 12040186 15173823 12697810 11940578 7545671 16227978 21035469 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 19085255 11279232 9271440 18039929 18775330 11705993 10601235 12792650 11431469
MAPK1 STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25679014 25846811
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
FGF19 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
STK11 STRADA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15509864 18687677 19197243 19942859 20160076 20484410 23030059 8910387
STK11 STRADA â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15509864 18687677 19197243 19942859 20160076 20484410 23030059 8910387
STK11 STRADA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 20562859 25241761 12805220 14676191 21860411 19513107 15561763 25852190 15733851
STK11 NUAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18083107 14976552 17242355
NDUFS8 NDUFAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA6 NDUFAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA6 NDUFAB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS8 NDUFAB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS8 NDUFAB1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PDGFD PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1520781114514730 23331499 15207811 21098708 14514732 15207812 28267575
ROCK1 ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19103606 19673492
NDUFS8 NDUFA6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS8 NDUFA6 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS8 NDUFA6 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
ROCK1 PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25681442 22479341 18573880 29849894 25084196
RPS6KB1 PFKFB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2846551 9211863
CSNK2A1 PIP4K2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10508590
GGCX F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3944102 10556651 31226734
F2 GGCX â—¼   CARBOXYLATION ✅ 4.0 1.0 Reactome 10917896 10068650 11513608 8530480