HGS
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20308550
0911188107
|
PLCG2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
ATP5F1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MAPK3
|
GAB2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217186
15356145
|
MAPK3
|
MYLK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15310280
10402467
|
NDUFV2
|
OTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
LCE2A
|
GRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NTAQ1
|
HPRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TGFB1
|
NOS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10362813
|
OGDH
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PAK2
|
MYLK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10748018
10092231
|
MVD
|
GNB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GAPDH
|
TK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
USP30
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
C1orf94
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ADCY6
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
NSDHL
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ZC3H10
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ARID5A
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ATXN1
|
ZC3H10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
PLA2G10
|
STK16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
LCE2B
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
BAG3
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
FOXH1
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
PLA2G10
|
TLX3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
HOXC8
|
KPRP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
GATA5
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
LCE2D
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
LCE2A
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
ALDOA
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20029029
31980649
|
KPRP
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
COX6C
|
COX5A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
23260140
|
NTAQ1
|
MTMR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
KRTAP26-1
|
PITX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
COX5A
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
PLA2G10
|
ZC3H10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
GRN
|
EGFL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AURKA
|
MTMR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
28675297
|
GSTM2
|
GSTM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PLA2G10
|
SNRPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
OTX1
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
HOXC8
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
KRTAP26-1
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
KRTAP26-1
|
LCE2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
PITX1
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
EGFR
|
PLCG1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
1689310
|
LCE2B
|
LCE2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
LCE2A
|
LCE2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
LCE2B
|
PLA2G10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
EGFR
|
GAPDH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
PLCG1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
9020117
6805619
|
EGFR
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CATSPER1
|
PAK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
SWSAP1
|
ZSWIM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
GSTM2
|
GSTM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
FOXH1
|
ZC3H10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
BAG3
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10980614
21233200
|
MAPK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23477725
12953068
20308550
23153581
23602387
25588945
18508924
15212941
|
KPRP
|
STK16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
PLCG2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
31980649
22973453
24658140
16273093
25402006
|
EGFR
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
1689310
11983899
14568990
15144186
12803489
12601080
24797263
9756944
9207933
19605547
7993895
7693694
9020117
12061819
16273093
25754235
16713569
22973453
7682059
8657103
8885868
|
PAK2
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
25416956
9535855
17353931
20696164
10320322
20936779
9822598
16204230
32707033
31871319
21311754
|
TK1
|
TUBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GNGT2
|
GNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8636150
19168127
19376773
|
TK1
|
DYNC2I1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NDUFB2
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
EGFR
|
PLCG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
LCE2B
|
OTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
TUBA4A
|
TUBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
EGFR
|
PLCG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
KPRP
|
OTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
CATSPER1
|
KPRP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
COX5A
|
COX6A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
COX6A1
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
COX5A
|
COX6A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
COX6A2
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
COX5A
|
NDUFV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CDC42
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
GNB5
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNGT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
12556561
1651322
17081983
3138233
15901825
1939237
91332050
2543683
2115882
17192257
1651323
15302935
|
MAPK3
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
1651322
17081983
3138233
15901825
16785992
1939237
91332050
27531070
17570479
2543683
2115882
34086370
17192257
1651323
15302935
|
TGFB1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20953304
32103204
19132220
28943431
|
EGFR
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
89.0
|
1.0
|
Omnipath
|
19901323
17081983
16273093
9207933
2472219
16497976
15592455
16126727
16713569
24797263
17389395
8578591
23331499
7991458
1689310
20068231
17570479
9176240
12803489
16153436
7993895
16038803
7805859
15864276
1708307
7682059
15144186
11983899
12601080
9756944
15212693
14568990
12061819
9020117
8885868
12648464
8657103
15951569
17016520
7693694
|
EGFR
|
PLCG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
31980649
25241761
16273093
24658140
17570479
25402006
|
EGFR
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12953068
17016520
|
MAPK1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12975377
23602568
16424009
19058874
23397142
21707490
|
MAPK1
|
GAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12008033
15356145
|
MAPK1
|
PDE4D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
16973330
9915826
10828059
10022832
|
MAPK3
|
PDE4D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16973330
11030732
10828059
10022832
27595237
|
MAPK3
|
GAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
12008033
15356145
|
MAPK3
|
NOS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17804409
|
NPPB
|
NPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
2570358
|
PAK5
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20936779
11756552
12032833
16189514
32296183
|
PLCG1
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19124833
9989831
15548136
19574218
|
NDUFV2
|
NDUFB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV2
|
NDUFB2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
COX5A
|
COX6C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
COX5A
|
COX6C
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11389896
15119951
16051147
17418790
19625251
8194600
|
CDC42
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
8107774
10559936
25416956
10320322
23331499
15020669
11340065
15003621
20936779
10934474
11413130
17353931
9535855
11950587
19628037
32296183
16204230
20696164
11248548
9822598
18719708
10613909
9823899
10461188
|
PLCG2
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19124833
9989831
15548136
19574218
|
PAK2
|
MYLK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
2160950
18088087
10748018
|
AVP
|
AVPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2991279
4065330
8106369
7929452
|
AVP
|
AVPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
15084136
9334232
10519430
12446593
10780976
9884074
1560825
9322919
9264324
9459574
9864265
8106369
10866830
|