Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AGT CPA3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2443571 2708524
AGT ANPEP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 15687497 17803194
VDR REN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17622742 17687191
AGT AGTR2 â—¼   UP_REGULATES ✅ + 0.81 0.81 Signor 16597412
ACE AGT â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
SLC3A1 SLC7A9 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AGT AGTR2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KLKB1 KNG1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
C1QBP KNG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8710908 34804054
KLKB1 KNG1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 291905 10464316 500690 17598838 7686159 7944388
REN AGT â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 22193701 12045255 12927775
AGT MME â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15283675 17704566 14747736
AGT CTSG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6807977 9570564 20889553
CTSG AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11747312 10899625
COL4A1 COL4A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
AGT REN â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ATP1A1 FXYD2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACE2 SLC6A19 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ATP1A1 ATP1B1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
KLKB1 C1QBP â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
PRCP C1QBP â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
AGT ACE â—¼   CLEAVAGE ✅ 10.0 1.0 Reactome 6269175 2846041 1848554 10536878 2558510 12540854 3017438 6270633 1668266 1851160
ACE AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11076943 10969042 23056909 15283675
REN ATP6AP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1204525512045250 12045255
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
AGT CMA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11502696 10899625 6807977 2266130
REN AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16816138 12045255 20927107
AGT REN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32201502 12045255 20927107
AGT MAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1282979212829790 12829792
AGT AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12006574 21464395 10193788 10993080 16189514 15930094 9797979 16597412 17346243
AGT AGTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 2775266 21464395 8315512 21542804 17138938 8185599 15930094 9797979 8242249 7850406
KNG1 KLKB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
KLKB1 PRCP â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 14996700 12123826 11830581 8344943
KLKB1 KNG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 3650269 500690 7944388 10464316 7686159 27006387 28966616 291905
KNG1 PRCP â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 14996700 12123826 11830581 8344943