Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RSPH14 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DVL2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CASP3 PPP3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11478781 16189514
DVL2 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
BCR CLTC â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
NUMB EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24797263 20029029
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EPHA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0808987105 18948590
FXR1 FMR1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21653829 3002166
FXR1 SH3GL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PRR13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HGS ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
HGS VPS37D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
MYO6 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PSMD4 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
PSMD2 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16763564 5218720
PSMD2 ADRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
ADRM1 PSMD2 â—¼   COLOCALIZATION 2.0 0.8 intact 16990800 5219132
PSMD2 PSMD4 â—¼   COLOCALIZATION 2.0 0.8 intact 16990800 5219132
RNF111 SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LRRK2 FAM90A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DVL2 FAM90A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
FAM90A1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BECN1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
AP1B1 CLTA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8909539 11050117
L1CAM CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17253643 8592152
GRIA1 BECN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BECN1 UQCRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SH3GLB1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21311563 17891140
DVL2 ZNF581 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
ZNF581 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SHC1 DDR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215174 11884411
FGFR1 SHC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 17496910 25467007
CRK TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
BCR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8978305 21602891
SMURF2 SMAD3 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8308197 22045334
SH3GL3 NDUFB9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRRK2 UQCRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DVL2 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
DVL2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
NECAP2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MEA1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
DVL2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
DVL2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
NUMB EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221644 9303539
CD4 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMURF2 DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16950122
TGOLN2 FURIN â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
GRIN2B DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215250 11937501
DLG4 MPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
MAP3K10 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11152698
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
ITSN1 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211195 10064583
STON2 EPS15L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6179743 18200045
TSG101 VPS25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
VPS37D VPS25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
TFAP2A L1CAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12077189
ATG9A TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 21169990 8141833
H2BC21 SFRP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KIF4A KIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10747093 10804209
H2BC21 ATP2B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 MAP3K9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FAM90A1 ZNF581 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
AP2S1 NECAP2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
AAK1 AP2M1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 11877461
SHC1 FGFR1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 16713569 7514169 7559490 18022941
SHC1 CD22 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10748054
FGFR1 CRK â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10464310 25241761
SDHB UQCRB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
VCAM1 AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AMPH AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NUMB EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
ADRM1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
RHOB EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
EGFR PSMD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24797263 24189400
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
RHOB EPHA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
BMI1 FXR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
HGS ARRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
RHOB MYO6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
MYO6 EPS15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 29467281
MYO6 AP2A2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 29467281
MYO6 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26950368 11967127
RHOB NDRG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
LRRK2 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
ESR1 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
CUL3 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22466964
VCAM1 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AP1B1 AP2A2 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
AP2S1 AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NUMB AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 23211419
AP2A2 AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
AP2A1 AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
VCAM1 ARPC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NUMB AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 23211419
DAB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
VCAM1 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AP2B1 FCHO2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
AP2B1 SYNJ1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
AP2B1 STON2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
VCAM1 AP2S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AMPH AP2S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP2S1 ITSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP2S1 STON2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP2S1 FCHO2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AP2S1 AAK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRRK2 ADRM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24947832
RHOB NUMB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
BMI1 RRP12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
VCAM1 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RHOB ADCY9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
VCAM1 EPS15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RHOB BCR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
VCAM1 STON2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RHOB STON2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
VCAM1 RAB5C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RHOB FCHO2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
ATP6V0B ATP6V1H â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CTNNB1 CTNND1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
AP2M1 ITSN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32203420 33961781 26186194
EGFR EPHA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 15657067
EGFR AP2S1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 25754235 24189400
RNF11 EPS15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24377927 23222715 14755250
EPS15 AP1B1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12538641 33961781 19380743
AP2A2 DAB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22323290 11247302
AP2A1 AMPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 12057195 33961781
SOX2 NCOR2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 21532573 28794006
CLTC MYO6 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AP1B1 AP2S1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
AP2M1 CD22 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 12646615
ITSN1 AP2A1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28484035 32203420
STON2 EPS15 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6179743 18200045
EPS15 STON2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 6179743 18200045
ESR1 RRP12 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
EHD2 AP2M1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 15182197
SYNJ1 AP2M1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12057195 33961781 26186194
AP2M1 FURIN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 10593987
EGFR AP2B1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 24189400 7534311 23956138
EGFR AP2A2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 8548289 24189400 23956138 31959764
ARF6 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11533043 16189514 11867621
AP1B1 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11877451 12070169 10097102
CRK BCR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8943292 8978305 19380743
DAB2 FCHO2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22323290 27237791 28514442 33961781
TSG101 VPS37D â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AP2A1 NUMB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
FXR1 AP2M1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 21653829
ACE2 AP2M1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34709727 33436498
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
HGS DLG4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 12151521
CRK SHC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8035825 9837978 9461587 9617486 19380743 10464310 23397142
LRRK2 DVL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
NCOR2 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9702189 14715875 20392877 12738788 9171229 23403292
EPS15L1 ITSN1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
EPS15 AP2M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743
AP2M1 FCHO2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 24189400
AP2M1 AAK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743 25852190
AP2M1 MEA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743
AP2M1 BCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743 32203420
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
BECN1 AMBRA1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 23974797
EPS15 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 19380743
ITSN1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 18654987 22558309 33961781
AAK1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 25852190
MEA1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 33961781
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
EPS15 AP2S1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 19380743
PSMD4 ADRM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24811749 28514442 16815440 24429290 16990800 33961781 26186194 24121268
STON2 SYT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14726597 11454741 18200045 11381094
CLTC HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DAB2 MYO6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AMPH AP2A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PARK2 PSMD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AP1B1 AP2A1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
NDUFB9 SDHB â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SH3GL2 SH3GL3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AAK1 AP2M1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CTNND1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CRK PDGFRA â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PPP3CB PPP3CC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATG9A AP2M1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24603492 33436498 34799561 27934868
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
EGFR AP2A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24797263 20029029 24189400 23956138 25754235 7534311 31959764
AP2A2 AP2B1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12086608 16189514 33961781 34079125 26344197
CACNG2 GRIA2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
EPS15 FCHO2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21762413 19380743 27237791
RAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16331275 21217774
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ACTR1A ACTR1B â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
FMR1 FXR1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EPS15 HGS â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ATG9A AP2M1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 24603492
EGFR AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 20029029 31980649 24189400 23956138 24067654 25754235 31959764
STON2 AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 19380743 11454741
AP2M1 DVL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31340145 16189514 16713569
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 NUMB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 23211419 33961781 26186194
EGFR ARF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 24797263 20029029 31980649
EGFR HGS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23477725 12953068 20308550 23153581 23602387 25588945 18508924 15212941
ADRM1 PSMD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16990800 22863883 33961781 26186194 26344197
AP1B1 AMPH â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 9280305
AMPH AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10748223 33961781
AP2S1 AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12086608 16189514 33961781 34079125 26344197
EPS15 NUMB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23211419 10953014 9303539
EPS15 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10764745 19380743 10953014 8662627 9049247
AMBRA1 BECN1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
SH3GL2 SYNJ1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MFAP1 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
AP1B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24189400 7593184 33961781 26186194 19380743 26344197
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
PICALM CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16491119 10436022
EGFR CRK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16729043 9642287 31980649 10595738 22973453 24658140 11956190 16273093 9617486 25402006 12198159 8875975 9480911
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
EPS15 HGS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12551915 27008177 18362181 10809762 10514494 15772161
DAB2 MYO6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 33372034 18429820 31744880 11906161 19805065 15837803 11967127 19855435 29467281 31672988 22323290 17187061
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
ACTR1B CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ITSN1 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B ATG101 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AP2A2 SHC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8617812 16189514 31980649 16713569 24189400 19380743
NTRK1 SHC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25921289 7541035 28213521 9856458 10092678 10629055 29715200 8226808 8183561 10708759 8155326 12446789
SHC1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
FN1 CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
EPS15 CRK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 16713569 7797522 33961781 19380743
SMAD3 DAB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11387212 16189514 16713569
SMAD3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24424784 19597490 21798735
SMAD3 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16469949 12207925 15525600
NGF NTRK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10713102 10490030 9857023 1849459 9083066 14985763 11738045 11729324
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21118812 17620599 12070169 10097102
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
NUMB AP2A1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12942088 23211419 17203073
TFAP2A FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2822255 19699737 20046871
RHOB DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
RHOC DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
STON2 EPS15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18200045 19380743 11381094
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
ITSN1 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PCSK9 LDLR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18250299 22081141 25613181 18753623 17435765 23085658
AP2A1 EPS15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
AP2B1 ITSN1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
AP2A2 EPS15 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ADRM1 UBQLN2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
SMAD3 SMURF2 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ZNF581 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GRIA1 GRIA2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 14602821 24706758 18311135 10358037
EPS15 ITSN1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CDH1 CTNND1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
SHC1 AP2B1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 31980649 19380743
AP2M1 TGOLN2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SHC1 AP2M1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 31980649 19380743 24189400
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EGFR EPS15 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32377695 15701692 16499958 21226813 19109251 10953014 9049247 16429130
AP2A1 SHC1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 8617812 28514442 16189514 31980649 24189400 11302736 33961781 19380743
NDUFB10 UQCRB â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EPS15 STON2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CACNG2 GRIA1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
NDUFB9 UQCRB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
SYNJ1 AMPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10542231 14704270 9341169
EPS15 ITSN1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10922467 22558309 32203420 26344197 10064583
CLTC DNAJC6 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ACTR3B ARPC3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ACTR2 ACTR3B â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SHC1 EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7518560 8034616 31980649 23956138 9544989 8610109 7542744 25402006 16729043 8665853 15657067 9742218 24797263 10049786 12577067 9756944 23799367 25187647 20935677 10766863 18271526 11408594 7506413 10635327 10595738 24189400 19531499 7542991 20473329 24430869 8662998 9020193 8887653 16273093 25754235 9388490 31959764 26551075 16713569 22973453 24658140 11196191 28065597 20067773 8810340 21278788 30544639 9130710 11370743
FXR1 FMR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 29395067 7489725 26949739 21653829 8668200 24778252 24981860 26186194 10527928 31413325
AP2S1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 26344197
AP1B1 AP2M1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ACTR10 ACTR1B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ACTR1B DCTN4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
NGF NTRK1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ADRM1 PSMA1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LDLR PCSK9 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ACTR1A DCTN4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NTRK1 SHC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SHC1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
PSMD4 PSMD2 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 17646385 30479383 25036637 24256120 16990800 22863883 33961781 24121268 22939629 26344197
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PSMD4 UBQLN2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CDH3 CTNNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EPS15 AP2A2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 26822536 18362181 10809762 19380743 8662627 9049247
AP2A2 AMPH â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 9280305 9195986 33961781 8552632 10748223
GRIA1 GRIA2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
ADRM1 PSMC5 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NDUFB10 NDUFB9 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
ADRM1 PSMD2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ADRM1 PSMD4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACTR10 DCTN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
DLG4 GRIN2B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA1 PSMC5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DLG4 GRIN2A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MFAP1 PRPF38A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMC5 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD2 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA1 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
AAK1 AP2M1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877457 11877461
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
ATG16L1 CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20639872
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
TFAP2A EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16449191 8621697 14522076
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17145710 22558232 18950621 23481205 25402006 12040186 24797263 9535896 17389395 20068231 19568798 27316454 14585353 17496910 24189400 15657067 24658140 31980649 26067913 15951569 14996911 17016520
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR ARF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12446727
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
EPHA2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12400011
TFAP2A FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10612627 16886907 15930016
HGS SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
RNF111 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 17341133 14657019 18950738 16189514
PRKCZ STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11853558 18250273 19414597 16407220 18321849
CLTA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
ACTR3 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
DVL2 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10837139 20976471 20558317 10671551 17374729 21285348 11972058 21506126 11689703 10747897 16707567
CSNK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12432063
AMBRA1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21358617 22441670 23030059 23377657 23974797
AMBRA1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20562859 23974797 20711182 20417604 21358617 25438055 23954414 20921139 24587252 17589504 25499913 33562550
FN1 SHC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19342448 21844907 10714768 8598224
SHC1 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
SHC1 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PDGFRA SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15592455 9121430 9446569 12767520 10921922 10482988 10764799 17673906 17496910 12522270 9685404 10896916 9927207 8702728 12237775 8610109 9741627 9710204 10816433 11075717
NTRK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8155326 9715270 8226808 15056278 10708759 8552402 9856458 23331499 10629055 10092678 12446789 8524391 25921289 7541035 8183561
DDR2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11884411 16186108
PDGFRA CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 19426560 25241761 10733900 16713569 9546424 27686861
NTRK1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7657647 8552402 12446789 7509449
SMAD3 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
DAB2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16713569 11387212
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
PPP3CB LRRK2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
PPP3CB LRRK2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
PPP3CB LRRK2 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
NDUFB9 NDUFB10 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFB9 NDUFB10 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NGF NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17145710 8155326 9083066 11729324 27908981 22666365 17404842 24224055 25611061 14985763 9290260 9857023 28090201 12067229 23772401 10490030 11114882 27229480 1706478 11738045 10713102 9547236 1849459 9775403 17409494
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TFAP2A CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9328434 17224907 12391156 10523846 9632747 21377456 12903198
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CTNND1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 7542250 17261850 22752307 9535896 7651399 12707304 23180380 24424122 12640114 11226248 29207493 10225956 12427869 21670201 22850631 20371349 20940130 25468996 10409703 14610055 7876318 22715382 10629228 19711372 8660921 10931041
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
LRRK2 SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 25501810 24778241 22998870
DVL2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12958364
AAK1 NUMB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25904845 18657069
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
FURIN ACE2 â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 33493182 32532959 34929169 35343766 34561887 32512386 32362314 33494095 34732583
ESR1 PSMD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18457947 9253789 12648521 11696545 23580568
DLG4 GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 20018661 16990796 11997254 9278515 7569905 33000527 11937501 10488080 9581762 11723117 12738960 8601796
DLG4 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10336672 16990796 9286858 8922396 12419528 21653829 9278515 7569905 12399578 11937501 18400955 10648730 11222640 17360663 11677266 8601796
STON2 SYT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 11454741 26903854 11381094
CDH3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8227214 10381631 12800191 21255999 11889072
EPS15 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
CTNND1 CDH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8660921 14610055
PCSK9 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22081141 29209441 17435765 25613181 23085658 18753623 18250299