Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CNTN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PINK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2D2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN1 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAD23A ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RAD23B ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
VCP ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16525503 5218414
TP53 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19196987 0812256106
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBE2D3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
UBE2D2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
GZMB UBE4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11802788
UBQLN1 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
UBL7 RAD23A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
UBE4B TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16170377
VAV2 CBL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11262396 20940296 15345594 11313921
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
RAD23B UBQLN1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
OTUB1 UBE2D3 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
UBL7 RD23B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBL7 TERA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MPIP1 UBE4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR CNTN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
TTK CDC27 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20729194 12686615 22045814
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
CDC27 PTTG1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM2 TP63 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
UBE4B MDM2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21317885 24587254
UBE4B UBQLN1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
UBE4B P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26673821 21317885 24587254
PTTG1 CDC27 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16479161 21186364 27114510 16921029 24781523 22193957 20080579
CBL VAV2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
UB2D2 MDM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23652204 15950904 22902369 23695783 19372219 21084285 21965653 19219073 11724934 23871895 17159902 11713287 29269425 20874444 14517261 10722742 34408321 27249653 22301280 18665269 29057323 22157679 14769800 24980433 32350255 30017913 15280377 20705607 24127580 24567357 19619542 26025930 19816404 22989009 18632619 16338390 17349959 10562557 28553961 18451149
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBE2D3 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8379996 22124327
RAD23B UBE4B â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATXN3 RAD23A â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RAD23A UBQLN1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
P53 OTUB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22124327 24403071 27561390
RD23B UBE4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
OTUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
UBE2D3 UBE4B â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
UBE4B UB2D2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20696396 21317885 25801170 29326975
PTTG1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12355087 16713569 19117984
P53 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17545634 26556313 10766163 16713569 21761334
OTUB1 UB2D3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26752685 32296183 19549727 24403071 32842143 25416956 32049508
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
UBE2D2 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8379996 22124327
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
UB2D2 CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29643511 18632619 18996392 27609087 28791635 20675402 33627783 29326975 31120930 24113870 10514377 22266821 33617900 15117950 22301280
UBE4B UB2D3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20017557 20696396 33362245 15466860 23550736
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
MAPK3 PTTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10906323
TP63 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11714701 9405685 12374749
MDM2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20571051
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
UBE4B UBL7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BTRC UBE2D2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EGFR VAV2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MDM2 UBE2D3 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RAD23A XPC â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
RD23B XPC â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 24258024 24981860 28760956 28473198 21962512 17154534 10488153 22431748 16713569 10873465 9164480 9372924 11279143 9372923 9734359 11259578
UBXN1 TERA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 29685906 26389662 15362974 21135095 27785701 25416956 29540532 18775313
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
OTUB1 UB2D2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 26752685 32296183 20725033 19615732 19549727 26186194 23287719 22325355 28514442 30718280 32049508
P53 MDM2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21317885 11839577 23201157 21316347 25312347 22975381 17369817 21084285 30005830 23443559 21465263 10980696 17936559 10488081 16845383 21149449 22366412 23483203 29549180 14741215 26673821 11713288 18665269 15058298 29524278 28514442 22510990 25241761 22525275 19106616 22467867 25954860 10889512 16595680 24998844 15848166 28628118 28362432 17116689 33650658 14499615 24980433 10608892 26876197 17438265 22103682 22374672 16055726 7689721 17363365 19411066 12167711 23318437 18566590 31796886 30244831 12944468 23261415 27215386 27826076 11178989 19223463 17301054 9724739 32894144 21075307 29121928 19305137 17318220 20659896 20080206 7686617 11744695 18467333 23246961 23150668 23776465 16215989 9223638 16331255 31968249 17908790 14702041 15094782 11278372 28605833 31647545 24200963 10601022 21454483 27893708 21088494 32516735 16861890 26238070 20705607 21887275 19303885 25609649 12915590 31406141 27282385 25156994 23671280 15358376 23609977 25168242 19071110 22991965 22653443 22920093 7926727 17470788 26908445 27856536 26475964 19857530 11709713 11714701 30532073 19411846 11094089 20173098 17591690 9582019 12552135 20542919 28205554 14704432 15001357 29876924 25417702 23880345 20124408 19033382 22487680 30598450 33061576 22575647 9131587 17159902 31152661 17297477 9271120 25384516 24659749 21261729 12529318 22411991 14671306 22084066 20395212 21986495 29487367 33355139 23802716 23370271 23946421 22083959 32807901 15154850 29670376 27905468 35140242 25283148 22085928 11562347 10640350 19098711 32901886 21726810 25624478 25637791 21584881 16870621 12690203 12612087 15824742 11572869 25464845 26203195 22157679 30454706 28082682 9809062 17302414 19085961 24567357 25362358 17080083 17426254 15242646 22524527 29295817 16751805 11431470 26882543 30097011 18604177 20591651 22948151 24462112 10827196 20479273 31533005 22389628 21170087 20694676 17666403 11597128 33503543 14596917 18332869 10321734 21857681 16579792 16414131 18264029 21071676 30464405 17989425 20234175 10681559 27308622 19816404 30355102 19805293 9824166 25313037 16173922 24926618 16159876 26540344 18541670 32904724 17616658 12842086 26720344 27129163 22266868 27031960 32528731 22737255 15604276 16432196 19188367 1614537 22914926 24842904 15247280 32097779 23252402 17347673 16964247 17310983 22331460 30584071 22032989 24240685 31652301 10435614 24621507 24361594 15308643 32334023 16547496 20639885 17139261 15933712 21478269 15313915 23402884 21750659 11112690 19255450 22124327 25277184 19234109 21965653 27336364 15122315 22916255 22262183 15295102 31092600 25512388 16713569 26001071 27807478 31940492 20588255 20174603 20570896 20708156 27886165 17056014 19081178 29547122 23572512 16905769 15542844 19941302 10561590 28542145 32066565 16212962 10202144 28549433 10734067 21572037 18172499 9363941 15550400 17380154 10892746 14559824 22227409 18316739 33495326 17234751 15280377 31177307 24127580 19160491 17290220 8875929 12381304 16857591 18813780 10347217 21561866 24413661 31066983 20847049 21098709 25103245 8058315 22807444 30832340 21268072 20962272 26350565 30175854 20591429 22444248 32427887 16023600 24667498 11351297 11285227 11223036 18784078 11384992 10562557 19568783 31138778 21925390 11486026 19597489 9450543 31665549 22318540 27106262 24207125 15950904 18223694 23728348 22474335 34362424 22912717 20047188 14612427 14517261 30679555 18815136 18061646 28394340 34408321 18309296 11046142 15144954 12897156 23776060 15210108 27811966 19357310 22391559 16338390 29899406 34040386 26186194 11284721 15908921 23652204 33765973 31626714 17848574 9529249 25739118 30879903 10766163 15013777 22588298 18981217 29755129 30320499 11070080 22301280 27543608 30948704 19590512 15558054 12867035 24488098 27462439 18485870 17268548 22819825 31591476 23826318 21471462 9278461 16866370 22659184 19166840 20660730 29269425 31239268 32198344 25543083 17875722 10196247 15053879 21084564 16107876 16678796 17098746 19656744 30109812 11925449 17525743 16624812 30455251 19153082 28553961 21132010 26578655 32874188 31903119 29997244 19837670 20837658 26883110 21060154 33961781 33579943 20235143 15064742 26556313 22745160 20657550 20484049 16152627 11697899 18234963 24314634 12208736 30320919 11713287 28223335 30252118 10722742 31594538 19483087 22266850 24643130 20959462 33020477 21988832 12426395 19332559 23169665 12620407 23134341 27249653
UBXN1 VCP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
UBE4B VCP â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CBL UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
UBE4B TERA â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 21282470 26389662 33961781 29599191 12504083 20414249 26712280 14749733 27226613 18022694 28514442 19175675 16525503
ATXN3 VCP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MDM2 UBE2D2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MDM2 TP73 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
HGS STAM â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CDC27 PTTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11535616 17303408 8824189 15279786 12640463 7575488 10477750 17376779 19182530 15024386 9790499 18590585 17498870 17660363 15592459 19154723 11402067 19503101 18022367
TP63 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9151818 19340300 19554267 21093383 19672307 8995628
TP73 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12766778 18555006 11870517 18829110 11309270 14733783
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
TRIP12 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20208519
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
EGFR VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17389395 19531499 11516622 26910843 10938113 10618391 12577067 12454019 17016520
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
TP73 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20921405 15734740 20156675 10469568 11245471 10207051
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18499675 17700533 26025930 25417702 19218448 21088494 10321734 10469568 10435614 20588255 25301064 10207051 11223036 21261729
TP53 PTTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12355087 12403781 15016801
PTTG1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12355087 16713569
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
TTK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19332559 27885363 23700430 22852086 23948487
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368