Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LSM8 LSM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
PCNA CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
SFN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20005908 8009659
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
AKT1 USP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22706160
IKBKB AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
BDKRB2 USP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
TP53 BDKRB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15632413 10748162
TP53 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
USP15 BRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23105109
USP4 BRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23105109
BRAP USP15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23105109
CDKN1A UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7298683 19536131
CDKN1A RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
NLK CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556497
SMAD4 DCP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DDX58 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
DDX58 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
EDC3 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
MAP3K7 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219785 17363973
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
RIPK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21119000 18362886
TRAF2 IRF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
IRF8 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16484229
TP53 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10749849 16713569
LSM7 PPIH â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MAVS UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PRPF4 PPIH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216605 12907720
PPIH PRPF4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PSMC5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PSMD11 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMD11 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNAI1 PTP4A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21811102 17545014
RBBP8 RB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10779361 6550000
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RBL1 RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7711923 20206173
SMAD4 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMAD4 SNAI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18618014 18832382
UBC SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7718905 20385133
TP53 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14990988
TP53 TWIST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504427 20689556
USP4 TP53BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBC USP15 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
HUWE1 PCNA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22203964 25147182 27146073
MEPCE LSM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17643375 29845934
PPIH LSM4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 27173435
MEPCE LSM7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17643375 33961781
MEPCE PPIH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17643375 29845934
NLK TRPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 23602568
RBL2 RBL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15467457 17531812
MAP3K7 NLK â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PRPF31 SART3 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
TNFRSF1A TRAF2 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 10795740
MEPCE LSM4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17643375 29845934 33961781
LSM6 MEPCE â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 29845934
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
LSM2 LSM6 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HDAC2 SNAI1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MAP3K7 RIPK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
LSM8 PPIH â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
USP15 USP4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NLK TCF7L2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AKT1 AURKA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24412244 28205554 28628118
SMAD4 RBL1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12150994 16189514
UBC USP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CUL4B HDAC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618 30737378
PRPF4 SART3 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
LSM6 PPIH â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MEPCE PRPF31 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TRIM21 UBC â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
LSM4 LSM7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CUL4B PPIA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28225217 21145461
SART3 PPIH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 27173435
MEPCE PRPF3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
LSM2 LSM6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
LSM2 PPIH â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD11 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PRPF3 LSM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 29395067
PRPF3 LSM4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435 29395067
SART3 LSM6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 28514442 27173435 33961781
SART3 MEPCE â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17643375 33961781 29845934 19615732 24778252 28514442
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAP3K7 TNFRSF1A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAVS TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RB1 RBBP8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MAP3K7 TRAF2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IKBKB TRAF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MEPCE SART3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DCP1B DCP1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25036637 24981860 29395067 24778252 16364915 19966221
AKT1 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34278744 27505672 27166089
SMAD4 NLK â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23602568 21988832
UBC USP15 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MRE11A RBBP8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PRPF3 SART3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRPF19 PRPF3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MAVS DDX58 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17190814 19454348 30193849 20007272 20406818 20434986 30558248 21292167 28594325 20080758 16177806 18200010 29053956 22301138 22022264 16153868 29263274 26494172 26061460 33372174 16585524 31433974 21844353 19164550 30267576 22623778 33976430 20071582 16127453 21903422 20554965 34544279 21102435 24478431 33649232 32612200 22114345 19193793 17709747
SART3 LSM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 28514442 29395067 33961781
SART3 LSM4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 19615732 29395067 28514442
DCP1A EDC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DDX58 UBC â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
LSM4 PPIH â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
IKBKB TNFRSF1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
IKBKB MAP3K7 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
PSMA6 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PSMC5 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
EDC3 DCP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 27107012 32296183 24981860 27315556 29395067 26496610 24778252 16364915 26186194 19966221 28514442
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
USP4 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A USP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RBL1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
SART3 LSM7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19615732 33961781 15452143
TRAF6 MAVS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31390091 21903422 32511263 20080758 30527812 26221961 31806368 23545497 22908223 29125880 26385923 16153868 27348524
SART3 PRPF3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 15314151 15452143 19615732 20595234 12374753 16713569 28514442
SART3 RNPS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27990632 16713569 11477570
USP4 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
USP4 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53BP2 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 21513714 8152471
TRAF6 MAP3K7 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18758450
LSM2 LSM7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
LSM7 PRPF3 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
EDC3 DCP1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8153045 21516116
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
TNFRSF1A TRAF2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
LSM7 PRPF31 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
CDKN1A PCNA â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
LSM4 PRPF31 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
DCP1B EDC3 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
LSM2 PRPF31 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
SART3 USP4 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HUWE1 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SFN TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SART3 USP15 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
LSM7 SART3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 TP53BP2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
LSM7 LSM6 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 26344197 15231747 11920408 22365833 22939629 28514442
LSM7 PRPF4 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
LSM2 SART3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PPIH PRPF31 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DDX58 MAVS â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
LSM6 PRPF31 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
LSM8 PRPF3 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
LSM2 PRPF3 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
LSM2 PRPF4 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
LSM6 PRPF3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
LSM8 PRPF31 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
LSM8 SART3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
LSM6 SART3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
LSM8 PRPF4 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
LSM6 LSM2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 19628699 32296183 26344197 22365833 11920408 29395067 22939629 28514442 16189514
LSM7 LSM2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 19628699 32296183 14667819 26344197 15231747 11920408 22365833 22939629 29395067
LSM4 LSM2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 19628699 26344197 11920408 29395067 22939629 27247266 16189514
LSM6 PRPF4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
LSM4 SART3 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
LSM4 PRPF3 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
LSM4 PRPF4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MRE11A RAD50 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MAP3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMA6 PSMD11 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA6 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD11 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
LSM7 LSM8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LSM4 LSM8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPIH PRPF4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPIH PRPF3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LSM6 LSM8 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
LSM2 LSM8 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
LSM2 LSM4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
LSM4 LSM6 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
LSM6 LSM7 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF3 PRPF4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF3 PRPF31 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF31 PRPF4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
USP1 PCNA â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
USP1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19264559 35324534 19686080 18082604 23589330 20353596 19622404 19075014 16531995 18082605 19217432 18931676 33619839
CDKN1A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 23443559 25411249 20606006 8868473 15576034 16474839 25416956 20605778 16510448 18703516 23139781 11302688 11254741 26272819 16616141 21988832 11313979 7780738 17588519 12964161 25502805 10022118 8861913 16189514 26496610 16082198 8861969 17129767 18263614 26186194 22383522 22911014 7915843 7911228 27107012 23223023 17115032 32296183 19895794 18794347 19704162 10873631 9546435 8662825 31515488 21415862 9545252 11350925 12930846
AKT1 RHEB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17517883 17277771 18372248 12524439 17386266
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
AKT1 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
AKT1 TWIST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25847239 26759241 29314610 27623213 20400976 28099910
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
SMAD4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10878024 9618481 9865717 11786386 9307274 24052079 12429655 10962574 10415848
KLF4 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10749849 23884787 18483411 21652709 23861801 19737957 21132436 21224073 22750490 21763782 18645021
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
TWIST1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18504427 15555546 15856770 11585922
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
SMAD4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 9618481 17550342 12545156 11013220 15155580 11074002
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
DDX58 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 20554965 16127453 33372174 20007272 35075101 21419663 16585524 20406818 19052324 17020950 21903422 19164550 24478431 17190814 16713980 18200010 18948594 19193793 16177806 34544279 16153868 23843640 16785313 16301520 21844353 16125763 19036819 18977754 21102435 33976430 22301138 17709747 21200404 29263274 26494172 23499489 18207245 19881509 22844514 20080758
SNAI1 HDAC2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
SNAI1 HDAC2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
TRAF2 IKBKB â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
IKBKB MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
TRAF2 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 27387502 15725726 12547194 11359906 25241761 20449947 16713569 18362886 23007157 10795740 21119000 19150425
MAP3K7 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 24911653 11129660 25195736 16006187 16260493 15502405 14530355 10779355 28159912 10094049 10837071 15836773 25659581 10195894 9689078 17363973 10807933 15214841 16186825 16493424 10022904 18316610 10187861 12547194 33895773 28475177 16301747 15691841 15620648 15327770 29748387 19632174 11460167 17965022
TRAF6 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16260493 15691841 15620648 15327770 10195894 16186825 16493424 17965022 10094049 10837071
MAVS IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 16177806 16153868 21903422 17468758 18207245
KLF4 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18511453 16244670 17308127 21132436 17659301
TRAF6 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF2 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12547194 20038579 14633987 14743216 17384642
TRAF6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 19675569 17947236 19843958 10882101 19521662 11259596 17079228 28024152 31885808 19112497 22924441 10094049 27501752 18922473 11518704 11809792 16517750 19232515 10702308 16410796 14633987 19820695 22851693 10921914 18758450 12496252 12609980 21822258 12242293 25963657 24434549 27249171 22643835 21245467 17965022 26038599
MAP3K7 NLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 11071635 23331499 15082531 25241761 12482967 15764709 11404460 15640443 20194509 10391247 10823839 7693453 12709429 10377264
NLK TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16714285 14960582 12556497 12901858 11274345 20194509 18855897
NLK SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21988832 19690946 23602568
PTP4A3 PTEN â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 22677902 23691193 24376839 24686170
SNAI1 PTEN â—¼   DOWN_REGULATES ✅ - 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
SMAD4 PTP4A3 â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16713975 18471976 20609352 21053359 21084277 21614932 21811102 22073279 22970020 23178297 24403062 25139404 27222233 27526109 9389648
PTP4A3 SNAI1 â—¼   REGULATES ✅ 13.0 1.0 ACSN 10048576 16617148 16831886 17563753 17671186 18832382 20731704 21317430 22406545 23691193 24376839 7512751 7528107
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
SMAD4 RBL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12150994 16189514
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TNFRSF1A â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TNFRSF1A â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TNFRSF1A RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 25681446 11002422 20547836 8612133 18450452 27552911 26802121 10356400 19773432 18621737 23815148 16611992 22179575 12721308 21741934 7538908 18949366 21113135 8985253 10744744 10795740 21119000 22733818 10755617 27321185 15115707 24098568 18939944 18329793 20825417 20448643 15357952 21737329 12887920 24130170 15258597 24758719 16115877 19524513 18724939 16968706 22817896 28817177 18022363 19815541 25388546 21331078 22848449
TP53 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18281511 10101800 22427654 12640112 17404570 12447694 17361185
TP53 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20206173 17546054 18431400 21340684 20066118 20457558 20182602 11896572 6396087 14517281 21625211
SMAD4 SNAI1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16179589 16510505 16617148 16713975 16831886 17018611 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18768831 18832382 19208835 19412634 19597490 20731704 21041997 21042762 21199805 21317430 21577210 21614932 21883379 22006115 22331441 22406545 22514743 22945800 8515656 9389648
SMAD4 SNAI1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16179589 16510505 16617148 16713975 16831886 17018611 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18768831 18832382 19208835 19412634 19597490 20731704 21041997 21042762 21199805 21317430 21577210 21614932 21883379 22006115 22331441 22406545 22514743 22945800 8515656 9389648
TGFBR1 SMAD4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
SMAD4 TWIST1 â—¼   UP_REGULATES ✅ + 31.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 9389648
SMAD4 SNAI1 â—¼   UP_REGULATES ✅ + 41.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16179589 16510505 16617148 16713975 16831886 17018611 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18768831 18832382 19208835 19412634 19597490 20731704 21041997 21042762 21199805 21317430 21577210 21614932 21883379 22006115 22331441 22406545 22514743 22945800 8515656 9389648
TGFBR1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8774881 20060931 11274345 21614932
SNAI1 TWIST1 â—¼   DOWN_REGULATES ✅ - 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
TGFBR1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 18922473 22710166 23331499 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116
TRAF2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 26212014 8565075 8943045 8612133 16713569 16611992 22179575 11821416 7544915 12721308 21741934 10795740 21119000 19150425 27321185 25241761 15115707 18776134 15743837 15485837 20448643 12887920 24735611 20333651 18022363 19815541
TP53BP2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14985081 16139958 8875926 25502805 8016121 21513714 31515488 16713569 8668206 18275817 11839776
TP53 DCP1B â—¼   KO_DOWN_REGULATES ✅ - -1.65 1.64 PKG 28854368