Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HBB HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFE2 HBA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17196618 12920035
HBB HBA2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PRL ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25193864 19524120
TFCP2 H1-2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20701767 25165434
PIMREG HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0709227105 18757745
PIMREG HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0709227105 18757745
HDAC1 ABCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20037778 19435809
YY1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21169469 23705901
PPP2CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3CB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10409650 10911620
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
XPC ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16849332
FN1 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
PPP2CA BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11593413
ESR1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16262660 7479947
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
CBX8 BMI1 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
MAPK3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
CASP8 TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CBX8 RNF2 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
CCT8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CD79A FN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491104 18243143
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
YY1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22025288 18558095
TFCP2 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
COIL FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MECP2 CRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108082
ESR1 CRH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8408641
YWHAZ EIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TFCP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21655924 19966177
ESR1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10935492 12878732
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ESR1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
FAM120C TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
FOXA1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21947652
FXR2 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GATA1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15739164 21454593
HSPB1 GPANK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
SUMO1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
HSPB1 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 MECP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR1D1 HUWE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000438107 20534529
TFCP2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10586050 23220634
TFCP2 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15247904 17278996
TF IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11297622 11749962
SOCS5 IL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12242343 16451196
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MAPK3 PCBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17475908
MECP2 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFCP2 NEDD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
POMC OPRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7905839 8208289
PCBP2 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PCBP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PCBP1 ZCCHC10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PHF1 TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PIN1 ZCCHC10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZCCHC10 PPIG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PPP2CA TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20682773
PPP2CA SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20704570 23331499
TFCP2 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24150225 22615490
TFCP2 SAA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10455131 10899169
SIN3A SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
SUMO1 SRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12788062
SUMO1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
UBE2I TFCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBE2I XPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17693435 16030353
PCBP2 PCBP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
UBE3A RING2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 33542309 26216987 30040487 20351251
HDAC2 RING2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24457600 19293945
TFCP2 LTOR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31501420 34079125
F19A3 TFCP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F19A3 UBIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MTDC TFCP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MTDC UBIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STK35 UBIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFCP2 TF2L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ATM HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17478428 22213803
BMI1 FXR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
ESR1 HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 RBBP6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20184719 31527615
FOXC1 TFCP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 29091762
MECP2 FXR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFCP2 IP6K1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PCBP3 PCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34133714
SUMO1 SIN3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24654937 17036045
STK35 TFCP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MORF4L1 SIN3A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ANM6 TFCP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ANM6 UBIP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ANR29 TFCP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ANR29 UBIP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TFCP2 DJC27 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25416956 32296183 33957083
BMI1 XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34316702 24457600 20668194
HSPB1 GATA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32814053 20410505
MAPK3 HSPB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21575178 8774846 25241761
PCBP1 MET â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ESR1 FOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23403292 25303530 28336670 27926873
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
SMAD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31130994 10199400 14699069 11226163
HDAC1 MECP2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
HUWE1 HSPB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25277244 25147182
PPIG PCBP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22365833 27684187
PCBP1 PPIG â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HBA2 HBB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
TFCP2 UBIP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 20211142
PIAS1 ESR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 11117529 15666801
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
APBB1 TFCP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9685356 16189514 16713569
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
GFAP MEN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12169273 16189514
PCBP1 PCBP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23640898 27684187 16713569 26344197
PIN1 SMAD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19920136 19122240
MECP2 SIN3A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
NFE4 TFCP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16263792 11003662
HDAC1 DDX5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19995069 20022962 17369852 15298701 20663877
MECP2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14593184 12473678 16331260 14647463
HBA2 UBE3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RING2 TFCP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18629613 16189514 16713569 11865070
SMAD2 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21990365 17303001 15306544
MECP2 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18599437 14593183
CBX8 BMI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20543829 24981860 19636380 20601937 26496610 17332741 10825164 21282530 34316702 24457600 27705803 22325352
CASP8 PTPN6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8296476 18086677 706462200
CD79A PTPN6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23836650 7618087 9890995
TFCP2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
DDX5 UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25218447 17369852 25114211
DDX5 SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25114211 19995069 19596686
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
FOXA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21572391 20501593 24290378
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
ESR1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15028626 12810571 22962310
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
ESR1 TF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12459033
SMAD2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19397700 17481939 15954899
TFCP2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21361876 25609232
GATA1 NFE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16648487 20564185
MAPK1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15967790
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
MEF2C MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9069290 17210568 9988769
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK1 PCBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17475908
MAPK1 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19237534
MAPK1 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
MAPK3 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19237534
SIN3A MECP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9620804 14593184 23770565 22615490 9620779 10773092 15322089 11441023
TFCP2 MECP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11865062 15549394 19000991
MEN1 SMAD2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22275377 11274402 15150273
TFCP2 NFE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16648487
NFKBIA SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19297320 9734360 11124955
YY1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19402223 20430007
RET PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PPP1R1B PPP1CC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9108011 6087160 10604473
TFCP2 TF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20796026
UBE3A YWHAZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HAPLN2 KRT27 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PIAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
EIF3A RPS24 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
RNF2 CBX8 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 5219708 17332741
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
MRPL11 MRPS35 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 MORF4L1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
HDAC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
MRPL40 MRPS35 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CDK2 CDK3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 28514442 23455922 26186194 33961781
BMI1 CBX8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
PPP1CC YWHAZ â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RNF2 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16710298 5218667
BMI1 CBX8 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 5219708 17332741
HSPB1 CRYAA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 32814053 11700327 33961781 12601044
CBX8 RNF2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CBX8 RING2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19636380 26496610 17332741 21282530 18927235 24457600 27705803 22325352
RING2 BMI1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 15563468 24981860 19636380 12183370 22902369 26496610 23207902 25843776 27705803 12589020 17157253 28073915 18650381 34316702 31093962 16751658 21772249 29402932 22493164 26151332 22325352 16359901 26468281 15386022 20543829 32296183 16714294 27647897 24457600 20601937 16710298 21676867 25355358
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
SIN3A HDAC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12724404 16254079 12082111 24981860 17827154 22493095 9885572 12398767 26344197 21258344 9804427 12493763 14749338 12091390 12943729 25314079 26949739 12453419 15451426 23752268 9150134 18059533
MRPL11 MRPL40 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
APBB1 APP â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CCT8 PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BMI1 RNF2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TFCP2 HBA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2233727 20421208 18629613 8157699 9753426 10491335
ESR1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 3481434 9259323 7649480 18022314 2082192 10830306
SRF ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18337547 12505862 17303098 19269978 19608972 20093628 15576380 12530967 20016221 24446247 22461426 14970199 15269336
MAPK1 APBB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14697653
MAPK8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917434 14970211 24610780 20122754 15936948
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
CDK2 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM PARP2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
PPP2CA ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15510216
FGFR1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11019781 12601080
TFCP2 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765426 24105466 22848609 19217433 20410295 18075316 22677942
BMI1 CDKN2A â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 15640618 17936558 20818389 21383063 21678481 21685941 22796940
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
BMI1 RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16710298 22493164 22902369 20068231 22325352 25355358 17157253 16751658 26496610 16714294 26468281 26151332 12183370 12589020 21772249 25843776 20601937 32296183 21676867 27647897 15563468 27705803 16359901 24457600 19636380
BMI1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21383063 9308237 21678481 17936558 22796940 20818389 11283613 15640618 19404261 21685941
MAPK3 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24342355 17290218 26036637 29233910 24484936 20937773
PTPN6 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18086677
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
MAPK14 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14970175
PTPN6 CD79A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 7539038
CDK2 CDKN2A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 COIL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17570479 11102515
CDK2 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19556876 20682773 19237534
CDK3 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19556876 19237534
FOXA1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23443045 19340300
CDKN2A HUWE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 16915296 15989956
ESR1 CRH â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18597742 18404132 8408641 17947358 9408232 15126558 12161509 15564578
DDX5 FOXA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17495528 15343269 19718048 11682626 28539435 14675539
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
PIAS1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15666801 11117529
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
MAPK14 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15187187 18039929 18411303 12738796 20626350 11274345
YY1 FOXA1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
FOXA1 HDAC1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18586828 22164220 12556498 15358512 20564185 12556492 1559609 3243278 15833715 12379744 14695898 21220744 2461328 2911469 12193659 17196618
MAPK3 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15967790
MAPK3 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 9535909 19664994 9535905 12637502 15605363 8631994 17570479
MAPK1 GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22028470 9535909 19664994 9535905 12637502 15605363 8631994 17570479
NFE2 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9478996 18308612 16287851 12582249 7918632 12000849 12379744 12031797 9558374 10891470
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
SUMO1 HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
HSPB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12897149 9047237 16439988 19324872 18266962 14761954 9169414 10694513 19011223
SMAD2 IFNG â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
IL4 IFNG â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
PTPN6 IFNG â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
PTPN6 IL2 â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
RET MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 19901323 11522789 91184134 16156666 16497976 15592455 12571246 19415658 11826406 17389395 18578522 21109534 20068231 18452278 18669648 16153436 11522288 18691976 1378617 15972258 15935618 16094384 12388769 11971971 19651622 21842857 28450419 18707149 17016520 21455180
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK1 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11287604 11481231
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 PITPNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15125835
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
RET MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 17081983 8622669 16497976 15592455 15735649 7535770 17126298 16083285 20068231 18452278 18669648 16153436 18691976 18088087 17548358 15972258 10781613 19651622 15674326 7750576 17016520 15659558
MAPK14 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21902831 9069290 23331499 9858528 9384584 10330143 9753748 10805738 16189514 18988627 26660426
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14580335 16410802 8622692 8668171 9724653
MAPK3 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
RET MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 551.0 1.0 Omnipath 15956760 25485910 17240116 20385359 12527803 17621270 23612968 18212246 21860413 18097051 18851832 10645003 25679764 21423210 15007380 19934253 19935718 22356909 9677429 15781651 10849428 17188005 20667468 14625304 34380633 17377139 21423211 20010870 26186445 20736304 12376318 33627405 16740736 21561860 15004239 17901130 15212956 15897464 15143154 18819921 17157789 26297582 12138104 11777927 22158866 23195225 34473994 20494825 14963038 16778204 17391526 27683117 22689060 12444552 31933886 15059947 26823016 15657432 19377875 17142325 15486045 21460222 23431142 11159838 27654866 19941816 14718389 34375550 18593598 17360704 23997214 24501773 16163708 10604992 15297577 17106060 24396487 25893857 20361349 16822962 12554776 18454177 29434871 34530870 16141331 12356731 19169277 20543098 17685427 21478906 18463290 16250012 20534535 21228323 7535768 26617336 15963258 10617652 17196532 19995915 10464310 15315965 12082540 21685939 25730857 18305109 25703330 16928771 15681433 11083859 16076871 20395206 23146907 26246800 21454539 12660819 21220474 15866871 15637081 19858202 34403210 18032526 16195541 21829454 16459330 17209045 12808105 11585739 16162500 25833830 18246127 11864968 24418169 15935618 19925796 20160123 17056593 14998784 18215133 10508618 18775330 18760948 12952943 21768338 17317777 8155326 22258404 15788397 26919095 28213521 21192818 33798093 15851026 26242183 12402043 21868357 17064352 20927383 16380505 15035987 21454675 18957207 19193766 21188622 19050043 16904111 19888469 26073130 20185553 15282551 16790523 23405013 11994288 17510392 32081857 18941537 20930115 19106095 11043579 21499301 20145126 24427291 10958690 15939799 19088846 19286657 18424438 15308678 18198175 27323814 24338688 24252946 19956644 21478903 12014987 23017243 17525129 12511559 17615152 16505244 20122898 12077249 17123942 26035354 11278407 15665049 20531297 17292825 14976148 16449644 16461767 23361053 19261611 11502744 25658205 12149254 30327409 17560175 24352879 26586479 26804906 25779944 34125833 19118012 11352917 16740725 11884401 16464862 16641227 27323830 18063582 22955283 24561529 10779765 10542198 16135812 23564461 17210721 24469048 24803537 21602434 17110601 21045017 11073973 10597231 23687376 34556812 17341659 18692468 17579083 12384403 21408150 25417160 11752053 23325789 17371847 11970985 22327338 26265441 16840783 17283152 26616862 23188829 17239630 21487005 11024037 17053147 24363437 25682201 20234004 12391272 23644655 25638159 20808799 17922836 20129247 24913355 18451171 25483104 26296889 21081844 17404396 11287604 18263590 26317416 15541367 16467309 12765939 16331263 16498402 20485667 11230338 16387841 19543320 7687743 20228268 15630487 16774943 16710359 10803464 16844778 16574647 15994317 17495961 21215800 17590453 26382850 19002495 12909616 20599567 12558965 10667594 24711455 17255109 16038803 12370087 21072043 20008839 18805968 10206983 11875080 20231899 21499296 21908610 16002410 12821943 24292678 17525735 17928416 21057531 25236495 17283137 21659545 24403530 16919488 23378338 22973961 18847491 16682955 20840866 16153436 23542175 24492000 12526087 26556867 12133965 12433918 20065107 14610044 11959800 15580310 21730285 11046056 9124279 14707024 26725216 16452220 22212957 25811962 15696170 11416124 20498373 17157787 21653826 16149052 20022946 34262144 16434970 10558990 18045996 10925301 16280323 25581518 15899879 21441955 20566643 15466476 15657177 11706017 15059847 8444886 18519681 23528009 33513601 20138986 12368275 24608435 17062641 20082306 20375017 17537990 24567333 33820494 10712263 21278199 19011679 20145145 27582276 25640183 21730054 16177091 17250586 15879307 16728403 18299328 24269888 17303383 9482941 17671177 17173941 24095720 15304500 12874275 33828192 11827968 33731431 10799542 15328343 18838481 19036157 17634226 17110082 17855349 31722981 26079947 25002506 14559232 23584478 18593910 17114467 16373398 16931794 17016429 14676826 28415597 12029087 24269383 8626767 20478260 12097262 14764579 12181310 15100319 12384432 15271996 17562849 19036927 19326083 20072652 25940440 11922392 17913704 19494114 25596730 18938240 27449290 12897059 21478911 21123455 26804170 10940302 16624816 26876209 12048182 17150968 21478863 17307705 18658095 24995980 16582879 17289590 33667549 17209041 17890097 21726627 27662093 16843264 19426503 11103941 11940578 17906618 26234813 19029090 15007386 15958730 12576312 17667937 17785202 34480897 20647329 18941890 16446383 25562429 10867021 26985018 16413470 23178720 25578563 34437586 21738699 21258408 20388777 24681954 20459645 12242309 15289328 21575862 16185843 19147767 34497368 19153083 12124352 17371994 17567959 15611080 17297454 23012246 14557270 28542650 15713673 21129803 19460345 10958798 21772273 21900206 19205871 17591920 19217381 12963813 19718025 24469056 16624867 21149447 15728578 33902596 11971971 16455819 19112174 10751321 1835084 11016927 18267069 20410276 21980390 17409387 23831578 21477078 15558056
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 STMN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11718727 9525956 9126608
MAPK3 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 16156666 19413330 11027280 9620846 33676893 23331499 8226933 20068231 18988627 12193595 18491316 18691976 8388392 19651622 10197981 18775330 19115199 9604935 15212693
MAPK3 PLCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11287604 11481231
MAPK3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17804409
RET MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18669648 9312068 11062067 15911620 95141073 16153436 15755722
MAPK8 STMN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25869138 23893240 16618812 17570479 24589734
MAPK8 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18985696 25862939 15696159 11956222 19788416 21081103 15071501 18559254 7890696
SMAD2 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160896
SMAD2 NOS2 â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10925299 11074002 11279127 11399519 11792802 11875494 12193690 12702545 12809600 15265520 15644117 16127449 16179589 16713975 17260466 17689680 21042762 21614932 22331441 23390297 6357187 8871614 9389648 9670020
TFCP2 OPRM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21326195 23485395 18453338 20385708 19602036
YY1 OPRM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17990281 19164126 19765550
POMC OPRM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15464143
PIAS1 SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16524884 22578841 19217413 18806873 14609633 11583632
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
UBE2I UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15340381 12820959 18997815 15668399 18298802
PARP2 TFCP2 â—¼   KO_UP_REGULATES ✅ + 1.42 1.42 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
XPC TFCP2 â—¼   KO_UP_REGULATES ✅ + 7.57 7.57 PKG 28854368