Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
TOR1A COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MBIP COPS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
USHBP1 COPS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BRME1 COPS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
COPS4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
COPS4 RCBTB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
COPS4 NUP58 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS4 CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
COPS4 SYT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8092124 21102408
COPS4 TOR1A â—¼   COLOCALIZATION 2.0 0.8 intact 8092124 21102408
COPS5 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19180539
YWHAZ DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
RBX1 DTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17588513 19481520
RBX1 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15082796 17183061
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
YWHAZ STK11 â—¼   COLOCALIZATION 2.0 0.8 intact 8329523 22575644
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
TP53 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19196987 0812256106
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
TP53 PRNP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24339999 19064990
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
TP53 IRF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBE2M CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17439941
YWHAZ KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15314064 5217163
USHBP1 KRT19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MBIP CCDC85B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
CUL1 UBE2M â—¼   NEDDYLATION ✅ 2.0 0.8 intact 17914462 6175264
STON2 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8092124 21102408
NEDD8 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219675 17318178
BRME1 NUP58 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS2 CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
COPS7A CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CRBN GPS1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
COPS8 NEDD8 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
COPS4 CUL4B â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COPS7B CUL2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COPS5 ERCC8 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
COPS2 DCAF11 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
COPS3 DCAF11 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
COPS7B FBXO17 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
COPS5 CRBN â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
CUL1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22474075
DENR BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BTBD1 COPS3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
COPS7B RBX1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
COPS8 RBX1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DDB1 NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 18274552 16964240 21145461 18247557
VPRBP NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17609381 21145461 33355139
FOS DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 35140242 33961781 26186194
COPS5 VPRBP â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
COPS2 RBX1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
DDB1 SIRT7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL3 KLHL13 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
COPS4 EIF3M â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
CRBN RBX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24292625 30042095 23983124 27029275 26990986 33961781 20223979
CUL3 BTBD1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 34591642
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
COPS6 DDB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
COPS2 TCEB2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS3 TCEB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS4 TCEB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS5 TCEB2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS7B TCEB2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS8 TCEB2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS4 DDB1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
GPS1 COPS8 â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 24421388
DET1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 16949367 31973889
VPRBP CUL4A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17079684 17630831 20870715 18606781 30590706 31973889 17609381 25532805 21145461 19295130 30166453 33355139 16949367
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
COPS3 NEDD8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
COPS4 NEDD8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
COPS3 DCAF4 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
GPS1 COPS6 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 24421388
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
COPS3 RBX1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
COPS4 CUL4A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CUL3 UBE2M â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NEDD8 TCEB1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
STON2 SYT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14726597 11454741 18200045 11381094
COPS4 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS6 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS7A DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS8 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ERCC6 ERCC8 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL1 FBXO7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CUL4A DCAF11 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
COPS2 DDB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS8 CRBN â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS4 FBXO17 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDB2 RBX1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
COPS3 DDB2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CUL4B DCAF11 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
COPS6 CRBN â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
COPS3 CRBN â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
COPS6 COPS3 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24421388
CRBN CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24292625 31973889 33961781 21145461 27142104 27294876
ERCC8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 26496610 33961781 21145461 22902626
VPRBP CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22038470 31973889 28416635 26496610 21145461 33355139 16949367
DCAF4 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 21145461 30945288 16949367 32140073
CUL4B DTL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 31973889 24962565 23555860 16861906 26496610 33961781 31155351 21145461 16949367
DTL CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21628527 17041588 23478441 31973889 23555860 16861906 29424068 30623174 31155351 33961781 30649446 21145461 16949367
ERCC8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 12732143 29225035 21145461 16751180 26826127 22902626
DET1 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 17452440 16964240 14739464 16949367
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
CUL4A DCAF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33961781 16964240 21145461 30945288 16949367 32140073
COPS7B CUL4A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CUL4A ERCC8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CRBN RBX1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
KRT19 SNAPIN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
COPS6 TCEB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COPS2 NEDD8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS4 CUL2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS7A CUL4A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS5 DDB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
COPS3 CUL4A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 DDB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 CUL4B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DCAF11 DDB1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BTRC NEDD8 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
COPS6 DCAF11 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
COPS8 CUL4A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
COPS4 CRBN â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
DET1 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33911083 33961781 31155351 17452440 16964240 14739464 16949367
ERCC8 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16949367 22232169 28416769 29531219 17392787 12732143 31970402 16751180 26826127 22902626
DDB1 DCAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19966799 33961781 16964240 30945288 16949367
DDB1 DTL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21628527 17041588 23478441 16861906 29424068 30623174 33961781 31155351 30649446 16964240 33536335 16949367
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
DDB2 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16260596 28416769 16473935 25628365 26496610 12732143 33961781 30349055 20368362 16751180
RBX1 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 18247557 12481031
CUL4A CRBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24292623 24292625 31973889 32235678 23983124 26231201 25860244 26990986 27029275 33961781 16964240 32132601 21145461 27142104 20223979 27294876
CUL3 BTBD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 19995937 25011449 17543862 33961781 21145461 19295130
CUL3 IBTK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 25882842 33130828 33961781 29395067 21145461 29695787
COPS8 CUL4B â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS3 TCEB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS4 TCEB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 DDB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
GPS1 TCEB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
NEDD8 RBX1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
COPS2 CUL4A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
ERCC6 DDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
DDB1 CRBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23983124 29370161 28425720 24292625 26909574 26231201 25108355 25860244 16964240 27142104 24292623 26990986 30190590 27294876 26131937 32235678 29892083 27338790 32132601 20223979
DDB1 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22118460 28035050 12050362 24249678 26410533 22822215 28416769 29262658 16473935 18593899 30923324 16678110 16964240 20368362 12812979 19295130 16751180 19109893 17360488 16260596 27203177 17392787 10777491 12151405 32985517 14751237 22039351 17041588 12732143 11564863 9418871 19966799 33961781 26186194 34251884 16949367
DDB1 VPRBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21957298 25499532 26613412 30166453 17314515 18606781 28416635 24558487 19295130 30590706 24412650 17609381 27571178 25532805 16949367 28202763 27354282 20870715 25557551 19287380 33355139 26344197
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
RBX1 ERCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
ERCC6 CUL4A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
ERCC6 ERCC8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32355176 29531219 20541997 22032989 29225035 7664335 16916636 31970402 16751180 26826127 22902626
RBX1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19327355 17183367 12149480 15448697 10230407 12481031 29547696 32296183 11861641 15601820 30349055 22405651 25540389 10579999 19250909 21822215 21778237 29958295 22863883 33961781 33504946 28591624 17132228
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
TP53 IRF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11973653 20507321
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL2 GPS1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
COPS8 CUL2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
COPS6 RBX1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
COPS2 CUL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
NEDD8 TCEB2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
DDB1 GPS1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
COPS6 TCEB2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CUL4A GPS1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
UBE2M NEDD8 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 19713960 7294536
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
COPS2 CUL3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
RBX1 UBE2M â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
GPS1 COPS5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 7228517 19444310
GPS1 COPS5 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 24421388
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
CUL4B DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CUL4A DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
COPS4 RBX1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
DDB1 DET1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
COPS5 RBX1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
GPS1 NEDD8 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
CUL3 RBX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 19818716 15448697 12481031 11861641 30349055 25270598 20027226 22405651 26100637 19256485 11311237 19250909 25278611 26286618 20865015 15601839 19617556 29958295 33504946 12684064 24145166
DCAF4 DDB1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
BTRC RBX1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
COPS3 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CUL1 GPS1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
GPS1 RBX1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CUL5 RBX1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31253590 18805092 10230407 11861641 14564014 25912140 19250909 30349055 15574593 22405651
DDB1 DTL â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
CUL3 GPS1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DCUN1D1 RBX1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NEDD8 UBE2M â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
COPS2 CUL2 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
COPS7B COPS8 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL5 RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL2 TCEB2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
DDB1 ERCC8 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CUL1 UBE2M â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
COPS6 GPS1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CUL5 TCEB2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS7A COPS8 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CRBN DDB1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
DCUN1D1 UBE2M â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
COPS2 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
COPS6 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CUL5 TCEB1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RBX1 CUL1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 12504025 20832730 15448697 10230407 19933270 12840033 12904573 18723677 12504026 12481031 17452440 12609982 26540345 27697867 22474075 11245432 22767593 28152074 22822056 19245792 12706828 11861641 20399188 10748083 11956208 11483504 27910872 16759355 30349055 10713156 11027288 21765416 20638939 22405651 23770852 19942853 10648623 12565873 18826954 18805092 32145688 21169563 27591266 22660580 11961546 32313199 15361859 19250909 29863914 24949976 10230406 32726803 30653357 32015321 33692209 16123592 34237211 29958295 29103612 33961781 33504946 12684064 26725323 26344197
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
COPS5 COPS7A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CUL2 RBX1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPS3 COPS7B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS7B GPS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS2 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS4 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS4 COPS7A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS5 COPS8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS6 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS2 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS4 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS7A GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS8 GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS2 COPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS4 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS6 COPS7A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS3 COPS5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS3 COPS4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS4 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 COPS7B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
TCEB1 TCEB2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS4 COPS5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
DDB1 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
RBX1 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
UBE2M CUL4B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
UBE2M DDB1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC8 DDB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
RBX1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DTL CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21145461 19231300 16949367
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
ERCC8 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22902626 16751180 7664335 20541997 16916636 26826127 22032989
ERCC6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 10882116 19221478 18784753
RBX1 ERCC8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 CUL4A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
CUL1 RBX1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RBX1 TCEB2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 CUL2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 TCEB2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 154.0 1.0 Omnipath 17053147 12684064 20638939 11967263 19797085 19258535 26540345 18826954 15071497 15448697 21765416 25730849 10230406 23343194 21169563 22270359 19250909 23732914 11359933 12051714 20006983 15361859 10748083 19352404 22682247 18787170 12504025 18636226 16469695 15459660 20211143 10535940 15001769 26725323 19411070 11861641 26159692 16697054 1570337 19751508 22822056 11348595 7542250 7641885 19849719 16759355 12820959 17452440 19622404 15703371 10648623 19245792 23331499 9694792 19150432 23180781 19597341 16189514 22474075 18988627 22767593 17143292 24949976 10713156 23770852 22405651 19942853 18196958 20399188 16713974 26192618 11027288 17884153 19933270 22730322 21411632 11961546 17936032 19809470 15147722 19270156 19576224 11483504 20976471 12504026 24023259 12840033 15340381 12904573 20558317 11900249 14536078 19686080 12565873 18805092 15489953 19557001 26885856 17652783 12481031 20843316 11955436 21071413 16039586 11956208 20705860 8666229 17928543 10023660 19836308 16940750 12706828 19143635 15688063 10671552 16123592 19366350 19847258 12417738 11245432 20832730 12648680 12609982 19619488 10230407 18931676
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
UBE2M CUL4A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
TCEB2 CUL2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB2 CUL2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
UBE2M CUL1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
UBE2M CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24949976 10713156 17914462 21247897 18805092 21946088 19245792 18826954
TCEB2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
UBE2M CUL3 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 19617556 18826954 25349211 23912815 25314029 18206966 21940857 23201271 26906416 19250909 30610225 25531226
STON2 SYT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 11454741 26903854 11381094