Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CUL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DDX41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 POLD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19231300
OGG1 APEX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11139613 25086253
APEX1 OGG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20185827 17203305
SMARCA5 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19092802 19234442
SMARCA1 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMARCA5 BAZ1B â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19092802 19234442
RAD23B BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
H4C6 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16628214 5218530
POLR2K BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10725406 16713569
BRCA1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 12700228
PARP1 CETN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
RNF11 COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPA2 COPS6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 RFC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PARP1 CUL4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
XPC DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
XRCC5 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
GTF2H3 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557 10734072
POLR2C ERCC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
GTF2H4 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9118947 10734072
ERCC5 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557
ERCC4 XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
XPA ERCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17948053
H2AC4 ERCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IKBIP ERCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ERCC6 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ERCC6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16319174
ERCC8 HMGN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16916636
ERCC8 XPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8999876
POLR2C GTF2H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
GTF2H1 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11259578 26278177
GTF2H2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10949034
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
H4C6 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
HMGN1 KAT2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16096646
KAT2B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880483
DDX17 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17226766
RIF1 MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RNF11 MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
OGG1 XPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219057 16957781
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 RBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 RAD23B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 SPTA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
TP53 POLD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11375983
POLD1 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 10852724
POLE2 POLE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 32296183
RAD23A PSMD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
RIF1 RFC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPA2 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 POLR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NCL RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15743838
UBB SFPQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SFPQ UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCA5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218974 16917504
SSBP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19066201
CEBPB TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8524227
TP53 ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
CBX6 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
XAB2 SF3B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
NFKB1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100018
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
CEBPB ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16989641
CEBPB MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9743233 22139077
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
SF3B2 PRPF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
POLR2C POLR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C POLR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
H4C6 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
HMGN1 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
CCNH POLR2C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCNH POLR2J â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2H2 POLR2B â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2H2 POLR2I â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2H2 POLR2C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2H3 TCEA1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
COPS4 CUL4B â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
GTF2H2 TCEA1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 UBB â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 RPS27A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 UBC â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
DDB2 HIST1H2AB â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
DOT1L RPS27A â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
DOT1L HIST1H2AB â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
HDAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CCNH TCEA1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
BAX P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32064756 25241761 21712378 25115399
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
DDB1 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 34026424 25189618 24249678 26679995
ERCC6 UBP7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31775559 22032989 26030138
MDM2 ATF3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15933712 29225035 31796886 20592017 34114479
RPB1 CSTF1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29180510 11459828 9002523
GATAD2B RBBP4 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CDK7 POLR2D â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ERCC6 RPS27A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ERCC6 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CDK7 POLR2C â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DDB2 HIST1H4A â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DOT1L UBB â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DOT1L UBC â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
GTF2H2 POLR2A â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CCNH POLR2I â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CTR9 POLR2G â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ESR1 APEX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
BRCA1 APEX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26831064
APEX1 RIF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28986522
APEX1 NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 28986522
APEX1 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 28986522
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL4B SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34026424 28225217
CUL4B RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
CUL4B UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28225217
CUL4B DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
DDX41 DDX23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25920683
CUL4A DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 32235678
ERCC3 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HNRPU ERCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 26030138
ERCC6 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16107709 32355176
GTF2H3 POLR2A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
UBC MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 19166840 6823655
BMI1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20668194 34316702
XRCC5 RFC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12393188 26344197
DDX17 SFPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 26344197
NOP56 TOP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 12777385
CUL4A NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30945288
RNF11 UBC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20676133 15231748
UBB UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12507430 27452404
UBB P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17936559 23443559
CEBPB ATF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20110283 20102225
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
NOP56 HNRPU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12777385 26496610
ESR1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 21182205 19805454 20348541
POLR2I POLR2M â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
CTR9 POLR2B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
POLR2H POLR2J â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DDX23 SF3B2 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST1H4A UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
UBB ZRANB1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST1H4A UBC â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
POLR2C POLR2M â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST1H4A RPS27A â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CUL5 TCEB3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CBX6 HIST1H3A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CCNH ERCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
P53 RBX1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22653443 30349055 23443559
RPA2 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11953755 31527615
BMI1 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20668194 24457600 34316702
BRCA1 RBBP8 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 16818604
RBBP8 BRCA1 â—¼   RELOCALIZATION ✅ + 0.83 0.83 Signor 24832651
MDM2 NCL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RPA1 XPA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF3 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
USP7 UVSSA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GATAD2A GATAD2B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATF3 MDM2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MNAT1 TCEA1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST1H2AB HIST1H2BB â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
BRCA1 H2A1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34321665 25131202 25355358 32092106 29367421 33589814
CUL5 RPB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19037258 21145461 30349055
RL10 ERCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31722399 26496610
TOP1 NONO â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15848144 24981860
PSMC5 VCP â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
XRCC5 TOP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28415827 21679440
TOP1 DDX23 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 15848144
TOP1 TOP2A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15848144 26344197
CBX6 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
ESR1 UBP7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23403292 31518603 31527615
ESR1 MTA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18451880 16645043
ESR1 EHMT2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
POLR2L POLR2M â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
DDX17 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15660129 32807901
MTA2 EHMT2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26028330 18451879
HIST1H2AB HIST1H4A â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
COPS6 DDB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DOT1L HIST1H4A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GTF2H5 TCEA1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST1H2AB HIST1H3A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST1H2BB HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H4A HIST2H2AC â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DDX23 SF3B1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GTF2H5 POLR2J â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
PCNA POLE â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PSMC5 RAD23A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CCNH POLR2B â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PSMC5 RAD23B â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BRCA1 TOP2A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15965487 25184681
COPS4 DDB1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
ERCC2 RPB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27193682 32355176
HDAC1 ERCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31722399 26496610 26030138
UBC MDM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17290220 19166840 18566590 19098711
ESR1 NONO â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33731348 25604459 31527615 20348541
ESR1 PSMD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25604459 20348541
XPC XPA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17154534 12486030
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
P53 UBC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17139261 19619542 18388957 18566590 17268548 18309296 17170702 17159902 17290220 19536131 17568776 19098711 19798103
ESR1 RL10 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23403292 21182205 31527615
POLR1A POLR2K â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MDM2 UBB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PSMD1 VCP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RPS27A ZRANB1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
RPA1 RPA4 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ERCC6 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
DDB2 HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
P53 APEX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 16189514 9119221 15824742
PCNA APEX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11601988 10559261
BAZ1B ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12837248 31527615
BRCA1 RFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 25184681 10783165
ESR1 CCNH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12527756 31527615
CDK7 POLR2B â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
HNRPU CDK7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17643375 10490622
CUL4B DDX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
RPB1 ERCC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32355176 26620705 20541997 9372911 34108663 16916636 10944529
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
PCNA PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20129057 20302655 12930846 21690293 20303835
PARP1 TOP2A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 20085707
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
XRCC5 TOP2A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12393188 20085707
POLR2J POLR2M â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
ESR1 RPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20308691 16957778 31527615 20348541
TCEA1 SF3B2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 17643375
HNRPU RPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15711563 21235343 18710935 10490622
ERCC2 XPA â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
GTF2H1 POLR2C â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
COPS3 RBX1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PSMB5 UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PSMB5 UBB â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HIST1H4A SMARCA5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ERCC4 RPA1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GTF2H4 POLR2J â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GTF2H5 POLR2A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MNAT1 POLR2J â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MRE11A RPA1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
COPS4 CUL4A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NCL TOP1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PSMC5 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD1 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD12 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMD12 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
P53 ABL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10713716 16713569 10629029
TCEA1 CDK7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26186194 9305922
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
DDB2 XPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22039351 23319653 28760956 27203177 29604309 15882621
NOP56 DDX21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 12777385 26496610
DDX5 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23443559 24219989 20818423 15660129 25144556 32807901
XPA ERCC6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8999876 20541997
XPC PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 28760956
PARP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16204234 11590148 25609649 16799643
HNRPU RFC4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 22939629 26496610
UBB RNF11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 14755250
HDAC1 EHMT2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 26028330 26496610 33961781 16287849
BRCA1 MRE11A â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS4 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS6 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ERCC6 ERCC8 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GATAD2A MTA2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK2AP1 GATAD2B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ERCC3 TCEA1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF2H4 TCEA1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PSMB5 RPS27A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RAD23B UBB â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDB2 RBX1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
GTF2H1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK7 TCEA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
COPS3 DDB2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PSMD1 RAD23A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PSMD12 VCP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDK2AP1 GATAD2A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
COPS6 COPS3 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24421388
ERCC8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 26496610 33961781 21145461 22902626
DDX5 RPB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29884807 17011493 12527917
P53 ERCC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8612585 16189514 16713569 7663514
ERCC6 ERCC5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16916636 8652557 16713569 16246722
H2A1B ERCC6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11003660 30021884
ERCC8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16949367 31973889 29531219 12732143 29225035 21145461 16751180 26826127 22902626
POLD2 POLD1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 31449058
NFKB1 SFPQ â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22536447 14743216
SFPQ TOP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15848144 9756848 24981860
P53 TOP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10468612 18697815 16713569 8639538 11805286 32807901
GATAD2B HDAC1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
GATAD2B MTA2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
BMI1 UBP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20800574 20601937 25605328
CUL4A ERCC8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HIST1H2BB HIST1H3A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CUL7 RBX1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
NBN RBBP8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MRE11A RBBP8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CTR9 POLR2D â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
COPS3 CUL4A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 DDB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 CUL4B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
POLD1 RPA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCNA UBB â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GATAD2A HDAC1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BRCA1 ABL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17352427 12024016
RBBP4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10220405 16713569 26831064
NBN BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10426999 18171670 19244116 12124328 10783165 25659039 25184681 25939603 11504724 29656893
CSTF1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29180510 11257228 11278247
HDAC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21102443 10220405 16713569
RPB1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14506230 18197258 10725406 16713569 12955082 22990118 25184681 27583302 29180510 29513652 15886201 11504724 9159119
CDK7 ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17643375 33961781 23602568 32707033 29568061
CDK7 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 9315650 9372954 9840937
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
TP53 CUL7 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8415349 22653443
ERCC8 DDB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16949367 22232169 28416769 29531219 17392787 12732143 31970402 16751180 26826127 22902626
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
DDB2 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16260596 28416769 16473935 25628365 26496610 12732143 33961781 30349055 20368362 16751180
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
ERCC2 POLR2J â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
XPC ERCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26278177 10734143
P53 ERCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 7663514 12379483 8612585 32807901
ERCC3 ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 8652557 17643375
PCNA ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10408173 16189514 16713569 9305916
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
P53 TOP2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32807901 10666337 16713569
HDAC1 TOP2A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11062478 11136718
P53 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19303885 25241761 11313951 10777477 16697957 10521394 19011633 26539911 20075864 12426395 22266186 16107876 17827154 11099047 16959611 20633551 14976551 18765668 32494626
DDX17 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15298701 19995069 20663877
BMI1 H2A1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34316702 27832544 29386386 26468281 33589814
BMI1 CBX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21282530 34316702 20601937 27705803 22325352 33961781 24981860
DDX23 PRPF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 34079125 26344197
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
MTA2 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11099047 12920132 32807901
CDK2AP1 HDAC1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
NONO SFPQ â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ERCC2 TCEA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BMI1 CBX6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
ABL1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16702947 25624478 12110584
TP53 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18208837
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
P53 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14710355 16713569 21742769 15571721 26140185 9926942 9582019 14636569 14978302 16677609 18501503 9482880 19509300 16969499 31073355
BRCA1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10426999 18171670 12124328 16713569 10783165 25084169 25184681 16260778 16391231 11504724 29656893
BRCA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17873885 11320250 14636569
CCNH ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 33707221 17643375 15220921 33453189 8692842 33961781 26186194 19934020 9118947 26340423 10734143
CCNH GTF2H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19172752 26340423 10734072
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
CETN2 XPC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21962512 17154534 28514442 11279143 26638075 27880911 28760956 33961781 22939629
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
RBX1 CUL7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17332328 24793695 24793696
P53 CUL7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17332328 17229476 23443559 24711643 22653443 31152661 35140242 31343991 33961781 25609649 26186194 25003318 17298945 16547496 16875676 31570706 17942889
CUL7 RBX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10531037 16142236 25752541 31343991 33961781 12481031 33504946 16547496 23045529
ERCC6 DDB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CUL4A DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22952844 17079684 22118460 15448697 26613412 22910413 25349427 21145461 22474075 27462452 16473935 15811626 18606781 26231201 18593899 16678110 16964240 33536335 19295130 25982117 33759138 16260596 27113764 21113133 30898011 28886238 26976604 27203177 17392787 25795299 22939629 26344197 14739464 27294876 10585395 27573245 31911655 17041588 20870715 27203182 31973889 32235678 16861906 19966799 22342275 34251884 17626091 19287380 30945288 16949367 32140073
DDB1 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22118460 28035050 12050362 24249678 26410533 22822215 28416769 29262658 16473935 18593899 30923324 16678110 16964240 20368362 12812979 19295130 16751180 19109893 17360488 16260596 27203177 17392787 10777491 12151405 32985517 14751237 22039351 17041588 12732143 11564863 9418871 19966799 33961781 26186194 34251884 16949367
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
ERCC1 ERCC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14517266 19940136 17948053
ERCC5 ERCC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 32245994 8652557 16713569
TP53 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8612585 16713569 7663514
GTF2H3 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9118947 8652557 10734072
RPA1 ERCC4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14517266 19940136 17948053
RPA2 ERCC4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14517266 19940136 17948053
RPA3 ERCC4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14517266 19940136 17948053
ERCC5 ERCC4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14517266 19940136 17948053
RBX1 ERCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
ERCC6 CUL4A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
ERCC6 TTF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16186106 18656484 12419226
ERCC6 EHMT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16186106 18656484 12419226
P53 ERCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22032989 16713569 10882116 7663514
ERCC6 ERCC8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32355176 29531219 20541997 22032989 29225035 7664335 16916636 31970402 16751180 26826127 22902626
ERCC6 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11003660 16772382
GTF2H3 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8652557 15790571 10734072
KAT2B P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19680552 17977830 16678111 15965232 20589832 10891493 12068014 17189186 9891054 10490106 16537920 9744860 12501250 14614455 16959611
KAT2B MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21209460 21060154 32404984 14769800 12068014 28286521
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
MDM2 UBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28406480 16474402 26238070 16943424 28196907 29295817 22056774 34799561 26971997 24462112 18566590 29236775 16402859 20713061 31647545 20816748 16845383 17380154 26460617 27452404 17936559 15916963
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
NBN RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
OGG1 NEIL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15260972 11904416 12097317
SFPQ NONO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17452459 18042045 11259580 21988832 25959826 30445466 12403470 31815296 30725116 34017080 33961781 24981860 17507659 30021884 22939629 26344197
P53 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 9312059 23169665 15044383 12898523 14627987 9565608 32807901
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
POLD2 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16000169 10852724 16510448
POLE4 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 6693436 10801849 9405441
PSMC5 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PSMD1 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RPA3 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
CAND1 RBX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29499133 18826954 12504025 15537541 12504026 30349055 12609982
RBX1 CUL4A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16189514 15448697 10230407 12481031 17452440 22474075 11861641 18593899 30349055 19295130 22405651 33759138 30352932 27113764 26976604 27203177 26990986 19250909 27203182 31973889 32235678 29958295 22863883 33961781 33504946 19287380 30945288 32140073
CAND1 RBX1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
RPA1 VCP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
RPA3 VCP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
TP53 POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
TP53 DDX3X â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24180280 23584477 21325288
MTA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11099047
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
ATF3 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 24554706 15933712 31796886 16169070 11792711
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
ESR1 DDX17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 11250900 21182205 20348541
ESR1 HMGN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8700510 17938209 18414489
TTF1 EHMT2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16186106 18656484 12419226
UBP7 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 23388826 31492752 17268548 16474402 26238070 30067985 22056774 17525743 21845734 22653443 31666375 11923872 24462112 29748603 29795372 16402859 14506283 20713061 21170034 30651545 16713569 16845383 20816748 17380154 31647545 32587091 23382381 25283148 26460617 32807901 15916963
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CUL7 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MRE11A XRCC5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PSMD3 UBC â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PSMD3 UBB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
GATAD2A RBBP4 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
GTF2H5 POLR2K â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2G â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2D â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2F â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2I â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2L â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2E â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GTF2H5 POLR2C â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CTR9 POLR2C â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ERCC3 POLR2G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2L â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2I â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2K â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2K â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2F â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2C â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2I â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2E â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2H4 POLR2L â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2E â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2F â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2L â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2I â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2K â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2C â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MNAT1 POLR2D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
POLE3 SMARCA5 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMC5 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD1 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD3 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
SF3B1 XAB2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PSMD12 RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
PRPF4 SF3B2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
COPS6 RBX1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
GTF2H4 POLR2B â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
POLR2J TCEA1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
KAT2B RPB1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 18710935 9710619
KAT2B TP53 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BAZ1B SMARCA5 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ERCC5 GTF2H1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
RAD23A RPS27A â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
POLD2 POLD4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
PSMD1 PSMD3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22863883 33961781 28292943 22939629 26344197
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
TOP1 TOP2A â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ERCC2 POLR2D â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2F â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2C â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2I â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2L â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2E â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2B â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2G â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC2 POLR2K â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
SF3B2 XAB2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
POLD3 POLD4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ERCC3 POLR2C â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
GTF2H4 POLR2A â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RAD23A XPC â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
POLE2 POLE4 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
COPS4 RBX1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GTF2H1 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GTF2H1 TCEA1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
UBC VCP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
RAD23A UBB â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CDK7 GTF2H5 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CDK7 GTF2H4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ERCC4 XPA â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
POLE3 POLE4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CCNH POLR2A â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
RFC2 RFC3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 9488738 26344197 24981860
PCNA RPS27A â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
RPB1 CTR9 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 16024656 26902284 26496610
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PCNA POLR2D â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PCNA POLR2E â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
POLR2I POLR2J â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
POLR2J POLR2L â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ERCC3 POLR2J â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
POLR2K TCEA1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
GTF2H4 POLR2G â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
RPB1 CDK7 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22379099 32355176 9311822 15009212 15328539 20106982 23064645 8692842 15282296 16327805 18391197 11278802 15530371
RAD23B UBC â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
PRPF3 SF3B1 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
MNAT1 POLR2A â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
RBBP4 SMARCA5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
POLR2L TCEA1 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
ERCC5 ERCC2 â—¼   PHYSICAL_INTERACTION ✅ + 0.95 0.95 Signor 20840796
POLR2D TCEA1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
PCNA TOP1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
GTF2H1 XPC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
POLR2A SMARCA2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
POLR2I TCEA1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MRE11A NBN â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
POLE POLE4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RBBP4 SMARCA1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
POLR2G TCEA1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CCNH ERCC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33707221 8692842 33961781 26186194 22939629 26340423
CDK7 ERCC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 8692841 33961781 26186194 11445587 23602568 32707033 22939629 29568061
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
RFC2 PCNA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9228079 12171929 24958773 26496610 8093561
PCNA RFC3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12171929 24958773 12766176 14657243 10051561 9092549 26344197
RFC3 RFC5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 24981860 22939629 26344197
RFC5 PCNA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9228079 12171929 16189514 24958773 8999859
RPA1 RPA2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24207024 22939629 26399832 26496610 24981860 16514417 19214185 26344197
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
CTR9 POLR2A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
SF3B2 SF3B1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21981285 32152280 12234937 28541300 24981860 10490618 22939629 26344197
GTF2H5 MNAT1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
RPL10 RPS27A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
POLR2B TCEA1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLR2F POLR2J â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
POLR2E TCEA1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
POLR2F TCEA1 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
PRPF3 SF3B2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ERCC3 POLR2A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PRPF4 SF3B1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
POLR2D POLR2H â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
POLR2C TCEA1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDK7 CCNH â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9334327 15698475 11113184 15328539 33707221 17643375 8078587 26340423 33476598 8521818 8521393 23602568 29568061 33453189 32707033 22939629 11713533 10958691 8692841 16782892 9218599 33961781 10082552 26186194 9056480 26344197
CUL5 RBX1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31253590 18805092 10230407 11861641 14564014 25912140 19250909 30349055 15574593 22405651
XPA ERCC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 25416956 18597777 11058119 7598728 24036546 9013642 9653453 7876167 8972858 19056823 8197174 16491090 26186194 33961781 17948053
ERCC3 ERCC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15220921 9118947 8652557 19934020 16669699 33381997 8152490 22939629 22678362 26340423 27193682
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
MDM2 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
P53 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19303885 25417702 34408321 17268548 23252402 23880345 22807444 15094782 20962272 12529318 21726810 22124327 18981217 16173922 23318437 15558054 22524527 30584071 31626714 22301280 32516735 20174603 22912717 21075307 15848166 18566590 23483203 26882543 23402884 14671306 15001357 10889512 17908790 19411846 10640350 21561866 14499615 33503543 21986495 24998844 15908921 26673821 17098746 25362358 32066565 25739118 29295817 34362424 16595680 20591429 27336364 22745160 24462112 32427887 18467333 26578655 23261415 9271120 16055726 19357310 31591476 23169665 16338390 10608892 30464405 15542844 12612087 22266868 15550400 22331460 22914926 19071110 7686617 14559824 20959462 19941302 14596917 25512388 27129163 19597489 25609649 32904724 11351297 29121928 22487680 11709713 24127580 10562557 15358376 21584881 25312347 27826076 19098711 24980433 24413661 21887275 17116689 14612427 30948704 26001071 19857530 33061576 31138778 23802716 20234175 25313037 21988832 17616658 11744695 17666403 22525275 12897156 25156994 33020477 11925449 16152627 29876924 30244831 1614537 17363365 22474335 11112690 23443559 17297477 27905468 19085961 20479273 31940492 21261729 14517261 26908445 16866370 27893708 22653443 17470788 10488081 23370271 19223463 16751805 26556313 10734067 19411066 11223036 27856536 14704432 20124408 24240685 24842904 32901886 22948151 19234109 35140242 21084285 32894144 17848574 22737255 10561590 25168242 10435614 11697899 25543083 21572037 22920093 18604177 32874188 22659184 17591690 16845383 22444248 31239268 25283148 26186194 24200963 23826318 7689721 20047188 24314634 12167711 15308643 17318220 21857681 11431470 18815136 15950904 20705607 17525743 26876197 31177307 9529249 22374672 12915590 33650658 10601022 20837658 18223694 30097011 28205554 32334023 15247280 23776465 21268072 27308622 11713288 18234963 9582019 18784078 29487367 23776060 11713287 20484049 26720344 9131587 30109812 33961781 24361594 32807901 31066983 15824742 11562347 21454483 22157679 21088494 11070080 22575647 22083959 26540344 15210108 18332869 32528731 18172499 11094089 21132010 16414131 10827196 27031960 10892746 15280377 16023600 18665269 10202144 15058298 29549180 16212962 16905769 11278372 20657550 9809062 15295102 26238070 22391559 18061646 17310983 18485870 9278461 21925390 20659896 9824166 23150668 25637791 30598450 19160491 28605833 12690203 22467867 31594538 11572869 11384992 11486026 27807478 17936559 30679555 16678796 30252118 31652301 15144954 22411991 22084066 30175854 21478269 27543608 16624812 17290220 32097779 17301054 20694676 11714701 24667498 20395212 16547496 12381304 8058315 22266850 29755129 22085928 17159902 10196247 21316347 27886165 27215386 25384516 7926727 16964247 19081178 32198344 11046142 28549433 26350565 31533005 12867035 10321734 19590512 22991965 25277184 24207125 18541670 19166840 25103245 30320919 26883110 20235143 17139261 11597128 21071676 19568783 18813780 19805293 17056014 17989425 21317885 17234751 20588255 21170087 10347217 11839577 25954860 21060154 24926618 21750659 16331255 29269425 27811966 19305137 24659749 9450543 23201157 30879903 16870621 28362432 21149449 20570896 23609977 33765973 27106262 33355139 34040386 22588298 22389628 19033382 18264029 27462439 31092600 12208736 17369817 28082682 16579792 23246961 20708156 15013777 21465263 28542145 23572512 19483087 31665549 22975381 17438265 15604276 11178989 24488098 16432196 22227409 28628118 30005830 20639885 20847049 9363941 31406141 19816404 26475964 29899406 16861890 30320499 20660730 19332559 14702041 11284721 18316739 19837670 25464845 12426395 10681559 17302414 16107876 22510990 15154850 21098709 19106616 10722742 19188367 22366412 29524278 21084564 23134341 25624478 30455251 20173098 12620407 9223638 16713569 17426254 31647545 10766163 30454706 21471462 24621507 23652204 19153082 8875929 31152661 18309296 31968249 31796886 15122315 30532073 10980696 17080083 15064742 11285227 29547122 21965653 33495326 23728348 15242646 17347673 12842086 12944468 19255450 23671280 22916255 17875722 30355102 14741215 23946421 20591651 15053879 28514442 25241761 24567357 16215989 19656744 30832340 22262183 27249653 26203195 16857591 15313915 15933712 28223335 20542919 12552135 24643130 27282385 20080206 28553961 22819825 33579943 16159876 9724739 17380154 22318540 29997244 29670376 22103682 22032989 28394340 31903119
RAD50 NBN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30179224 12607003 12124328 11238951 17612497 22941933 23530059 24651726 15758953 11062235 10426999 10783165 22464731 19197236 12447395 12679336 26215093 22939629 34348893 17526493 17500065 9705271 16391231 30440001 24981860 26344197 15734743
PCNA RFC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12171929 12192049 22939629 9649448 15225546 24958773 12045192 26496610 10353443 8861969 30301766 9092549 8999859 12400013 26344197
RFC1 RFC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9488738 14681455 15655353 18245774 22939629 26344197
PCNA RFC4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9228079 12171929 16189514 22939629 24958773 26496610 10051561 12400013
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
RBBP4 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 9520398 19703393 31435636 9150133 10444591 21258344 12943729 11102443 9885572 27068747 10471499 26496610 34518534 20127688 11171972 10734134 11470869 20585571 10220385 12091390 17643391 21670149 11602581 17827154 22939629 9150135 23752268 16713569 9790534 27705803 19686092 24981860 33961781 11302704 11118440 15451426 12920132 26344197
HDAC1 MTA2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 31980649 19703393 10444591 21258344 12374985 17956988 11102443 27068747 26496610 20127688 11171972 11297506 20585571 21670149 11602581 22939629 18451879 23752268 9790534 26949739 16645043 22863883 28179136 27173435 24981860 33961781 19686092 12920132 26344197
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
MTA2 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 19703393 22939629 14645126 10444591 27705803 28179136 33961781 24981860 21670149 19686092 11602581 12920132 11297506 26344197
RPB1 TCEA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9305922 23748380 9765293 20178742 17643375 20562857 16916636 22939629 12914699
POLE2 POLE3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CAND1 RBX1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DDX23 PRPF3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MDM2 RPS27A â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CETN2 XPC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GTF2H2 GTF2H5 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DDX23 PRPF4 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GTF2H1 GTF2H5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ERCC2 GTF2H5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ERCC3 POLR2E â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ERCC3 POLR2F â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RFC1 RFC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 22939629 14681455 33961781 18245774 9092549 26344197
RFC1 RFC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 14681455 33961781 18245774 22939629 26344197
POLR2E POLR2J â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
POLR1A POLR2F â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BRCA1 RBBP8 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CDK7 GTF2H2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
POLR2A POLR2M â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL5 RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
HIST1H3A KAT2B â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
POLR2F POLR2H â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
POLR1A POLR2L â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
DDB1 ERCC8 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
POLE POLE3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PSMB5 PSMD3 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPS27A TP53 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
LIG1 PCNA â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
POLR2F POLR2L â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
POLR2K POLR2L â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PSMB5 PSMD1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
RFC3 RFC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9488738 8692848 14681455 18245774 22939629 26344197
RFC2 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9228079 9751713 28514442 9488738 22939629 8692848 15655353 33961781 24981860 16582606 9092549 26344197
RFC3 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 32296183 9488738 22939629 8692848 33961781 9092549 26344197
POLR2A POLR2J â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
POLR2D POLR2F â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
POLR2H POLR2I â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CDK7 GTF2H3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMB5 PSMD12 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
POLR1A POLR2E â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POLR1A POLR2H â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ERCC2 GTF2H4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMB5 PSMC5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RAD23A UBC â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
POLR2G POLR2J â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
POLR2D POLR2J â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
POLR2D POLR2K â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BRCA1 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDK7 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MRE11A RAD50 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
POLR2J POLR2K â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
POLR2A TCEA1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDK7 ERCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ERCC2 GTF2H3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2H3 GTF2H5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLD1 POLD4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PCNA RFC5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLR2I POLR2L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCNH GTF2H3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2H3 MNAT1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2H4 MNAT1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLD2 POLD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLE POLE2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD12 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC5 PSMD1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD1 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD12 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RFC1 RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2E POLR2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SF3B1 SF3B2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2F POLR2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2G POLR2K â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2I POLR2K â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2C POLR2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2C POLR2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2G POLR2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS4 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ERCC1 ERCC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PCNA RFC2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RFC2 RFC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
POLR2B POLR2J â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
POLR2B POLR2F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCNH GTF2H5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH ERCC3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH ERCC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 MNAT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 MNAT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H3 GTF2H4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H4 GTF2H5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RFC3 RFC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2E POLR2F â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2E POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2E POLR2K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2E POLR2L â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2F POLR2K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2H POLR2L â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2H POLR2K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2G POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2C POLR2H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2I â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2I â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2D â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2D â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2A POLR2B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12919958 12024016 17352427
ABL1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19563810
ABL1 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17018282 17412694 11823473 17384675
ABL1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15448168 20841568
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17626041 20841568 27827925
ABL1 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12107171 20841568
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9874796 20841568
RPA2 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PARP1 APEX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17548475 11440997 12727891 15135726 10364231 11340072 9804757
LIG1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RPA1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 RPA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18786561 19180539 9119221 19737086 16713569
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
TP53 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11278953 12203124 16931621 9582019 17693666 11118038 12433990 11395510 8183578 11429705 10400708 15242522 11423991 19067706 24336083 18381427 22732402 15988033 16341121 10935506 10094833 16215989 17280505 10744634 12851404 20673369 15851483 8845569 10559267 12168779 11850816 19505426 8564971 11756653 19054058 15566940 12173040 17690113 8635454 18034190 10510469 10101800 11335718 23100276 9400998 9445173 9582400 24098340 22532570 9122197 11420692 11104574 15679092 11748232 12560513 11928223 20400479 20546728 17145718 20567883 20840522 18172861 10566557 10777477 7834749 12806965 17521288 19242108 9000137 21859835
MAPK8 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525785 18471544 16709574
TP53 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14963330 16151013 7834749
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 SFPQ â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 SFPQ â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
BRCA1 DDB2 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
BRCA1 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 21908405 18285836 16713569 15485915 25310973 9738006 17525342 17525340 16843262 24085845 25184681 26387952 18369654 9811458 16818604 20351172 23416467 19442256 10196224 10910365 19452558 11739404 25252691 10764811 25659039 17965729 11689934
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CCNH GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH CDK7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH MNAT1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH CDK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23602568 11113184 8521818 16782892 15698475 15328539 19153657 10082552 26340423 8692841 26186194 9334327 10958691 10734072 9056480 9218599 8078587 8521393 17643375
RPA2 CDK7 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 CDK7 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 MNAT1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 CDK7 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 CDK7 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 MNAT1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 XAB2 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
CDK7 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18079403 27197304 26799765 10886368 14662762 16327805 24662513 26748711 25561469 21331744 19667075 18079404 22137580 9130709 20457598 19901026 19450536 20932174
XPA CETN2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
XPC CETN2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
XPC CETN2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
POLD1 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD2 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
XPA CUL4B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
RPA3 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CUL4B POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CUL4B POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD2 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA3 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD3 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLD1 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
XPA DDB1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
ERCC8 DDB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CAND1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 21463634 12504026 12609982 23535662 21863050
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
RBX1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
XPA DDB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
RBX1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
RPA2 ERCC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 MNAT1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 ERCC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 XAB2 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
ERCC1 MNAT1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
XPA ERCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19056823 26186194 8972858 18597777 25416956 9653453 7876167 11058119 17948053 7598728 8197174 16491090
ERCC2 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC2 MNAT1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC5 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8652557 16713569 20840796
GTF2H1 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9130708 8652557 10734072
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699
ERCC2 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12820975 10734072 9771713 8652557 16189514 19934020
ERCC3 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10403766 10734072 9173976 8194528 15220921 9118947 9130708 8652557 11259578 26340423 17643375
ERCC3 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9118947 8652557 16189514 10734072
RPA2 ERCC5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17000769 9699634 7700386 15590680 9716411 17466625
RPA1 ERCC5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17000769 9699634 7700386 15590680 9716411 17466625
ERCC5 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17000769 9699634 7700386 15590680 9716411 17466625
ERCC6 ERCC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16916636 8652557 16713569 16246722
ERCC5 GTF2H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15195146 16713569 8652557 11259578
ERCC5 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18079701 10408173 16713569 19279666 9305916 20713449
ERCC8 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22902626 16751180 7664335 20541997 16916636 26826127 22032989
ERCC6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 10882116 19221478 18784753
ERCC6 XAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10944529
RBX1 ERCC8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 CUL4A â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
ERCC8 XAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10944529
GTF2H1 GTF2H2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H1 GTF2H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21988832 10734072 11062469 9130708 8652557 8194529
GTF2H2 GTF2H4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H2 GTF2H3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
GTF2H2 MNAT1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TP53 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9266967 20094059 15153330 17611664 18945670 14614455 17293853
KAT2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19680552 11804596 12068014 16537920 9891054 10490106 14614455 20589832 19788416 12660246 12501250 16959611 19407812 9744860 15965232 16678111 17977830 17189186
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
NCL MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24147044 16751805 22103682 20195357
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19805293 22056774 17290220
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
RPA2 MNAT1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
MNAT1 XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
MNAT1 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 MNAT1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
MNAT1 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
MNAT1 XAB2 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
MNAT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10428798 10949034 12527756 16076840 8308015
NBN H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
NBN PARP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PCNA NEIL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18032376
SFPQ NONO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17452459 21988832 17145710 17507659 12403470 11259580 30021884 10858305 18042045 20421735 25959826
NONO TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 10858305 9756848 17481653
TP53 OGG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16293709
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 XPA â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
PARP1 RBBP8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
PARP1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
LIG1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
POLD4 POLD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD1 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD1 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD4 POLD1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD1 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9286699 12403614 16510448
POLD1 POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12403614 16510448
POLD4 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
CUL4A POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
LIG1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RBX1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA POLD3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD3 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD3 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD3 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
LIG1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RBX1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CUL4A POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA POLD4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD4 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24022480 9038370 16510448
XPA RAD23B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H4C6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
POLD2 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA3 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
XPA RBX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
RPA1 RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA RBX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
VCP RBX1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
NFKB1 RBX1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
RBX1 TCEB3 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17884153 18420585 18931676 19622404 19622774 19686080 19809470 19847258
RBX1 TCEB3 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17884153 18420585 18931676 19622404 19622774 19686080 19809470 19847258
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
PCNA RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8999859 12400013 15225546 19285992 10353443 12192049 9649448 26496610 12045192 12171929 24958773 8861969 9092549
RFC5 RFC2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 28514442 9488738 8692848 33961781 24981860 22939629 26344197
RFC5 RFC4 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 16189514 9488738 25416956 22939629 28514442 29892012 32296183 26264872 8692848 33961781 24981860 30021884 9092549 26344197
H4C6 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
LIG1 RPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
XPA RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12527904 19446504 7665601 8972858 7876167 20304803 7565690 9535929
RPA2 XPA â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 LIG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 XAB2 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XPA â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
XPA RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12527904 19996105 10982866 8972858 20304803 7876167 11081631 7565690 32296183 20670893 9535929
LIG1 RPA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
RPA3 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
SFPQ TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9756848
TOP1 LIG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14699148 13679147
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
TP53 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12386811 12372430 17108111 21927023 21394211
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
TP53 XPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12771027 22336944 12242345 23050045 16357511 12967652 15927209
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
TP53 ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15933712 18431400 11792711 16169070 16713569
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
TP53 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12771027 9346961 10779360 21340684 19004803 10367887 20066118 12496474 12242345 20457558 20182602 10962562 6396087 9892649 12967652
UVSSA USP7 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
XPA XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
XPA XAB2 â—¼   PROTEIN_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
XPA CUL4A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
XRCC5 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLD2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
LIG1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12171929 9649448 28073635 10559261
LIG1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
POLD2 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
POLR2C POLR2J â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
POLR2B POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2E â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2E POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PRPF3 PRPF4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2F â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2F â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2F POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2L â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2G POLR2L â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2B POLR2L â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2L â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2K â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2B POLR2K â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2K â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2B POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2C POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POLR2A POLR2G â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105