SFN
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15778465
5217604
|
EZH2
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23624935
21406404
|
BRCA1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18025037
16331276
|
MYC
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP100
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
HDAC1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20049841
20821348
|
EZH2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20132185
21697275
|
CREM
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22488648
17185632
|
RASSF1
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12024041
|
EHMT1
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19010785
|
ADAM10
|
CD44
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18971959
26284334
|
RB1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9671466
14527674
|
SMARCA4
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18414052
|
TRIM28
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942393
|
CDKN1B
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
EZH2
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18980972
21765901
|
MYC
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24704206
26701207
|
MBD4
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
SUV39H1
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
MYC
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
SETDB1
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
KDM1A
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
MBD4
|
SUV39H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
STAT4
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10702306
|
MYC
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21925595
23722468
|
MYC
|
EZH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21941025
19197161
|
MYC
|
SMARCA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24285714
24362264
|
MYC
|
HLA-DRB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17881904
18544564
|
MYC
|
H2BC8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12747840
|
MYC
|
DHODH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18628958
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
CDC73
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18987311
|
RB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
7838535
|
MYC
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15616584
19786833
|
MYC
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9988278
|
SUV39H1
|
RASSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
RASSF1
|
SFN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8009708
20069457
|
HOXA9
|
RASSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17029216
17968314
|
RASSF1
|
DAXX
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
18566590
6799761
|
MYOG
|
SMARCA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17194702
23609547
|
SUMO1
|
SP100
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TDG
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218717
16763556
|
SUMO1
|
NRIP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18211901
|
H3C2
|
SUV39H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11242053
5213683
|
SUV39H1
|
DCAF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
DNMT1
|
SUV39H1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17172825
17584191
|
DNMT3B
|
SUV39H1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16371653
17584191
|
EZH2
|
SUV39H1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18980680
17584191
|
PAF1
|
SUV39H1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19906718
|
DNMT3A
|
TDG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17175537
|
TDG
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17175537
|
TFAP2A
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19701232
18754863
|
SPI1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17967894
7988559
|
KLF4
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20629177
22723415
|
UBE2I
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18082607
|
USP7
|
DAXX
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
6799761
18566590
|
OTX1
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
DCAF8
|
MDFI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
EZH2
|
HOXA9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20565746
|
PRMT5
|
HOXA9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22269951
|
DNMT3B
|
JUP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16887905
17998942
|
DNMT1
|
ASCL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15390277
16371653
|
MYCN
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18003922
0705524104
|
HDAC1
|
MYCN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18003922
0705524104
|
RB1
|
HDAC1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
SPI1
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14559995
12588990
|
RB1
|
SPI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8434021
|
FOXP3
|
CREM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20554955
17372992
|
PDLIM7
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBE2I
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18762900
11735126
|
GFAP
|
ATP6V1B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESR1
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11060032
21610700
|
DNMT3B
|
RARB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20426865
18798999
|
DNMT1
|
RARB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21868513
14528273
|
DNMT1
|
RRP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17172825
18049164
|
ESR1
|
CA12
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18451179
18414489
|
ESR1
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9259323
8625613
|
ESR1
|
ADA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11357058
18414489
|
EED
|
H3C2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17344414
17210787
|
DNMT3B
|
DNMT3A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20426865
15362956
|
DNMT3A
|
DNMT3L
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18544626
17965599
|
DNMT3B
|
EHMT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16371653
17584191
|
DNMT3B
|
WIF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23939044
16501252
|
H3C2
|
EZH2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17344414
17210787
|
EZH2
|
CDKN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20574448
|
PDLIM7
|
GFAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TFAP2A
|
TIMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8810321
|
RRP8
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18485871
23897426
|
TFAP2A
|
ACADVL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14611808
10607478
|
ATP5F1E
|
ATP5F1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CA12
|
ATP5F1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
1204073
5215931
11244506
|
CDKN1A
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
16765349
5218735
|
DDB1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
34026424
25189618
24249678
26679995
|
SUMO1
|
CBX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
20098713
33961781
22467880
24654937
|
SP100
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
BRCA1
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22990118
26831064
|
MYC
|
CBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
CBX1
|
EHMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
27705803
|
DNMT1
|
CBX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17470536
12867029
|
DAXX
|
CBX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
26496610
|
CBX5
|
EHMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
20562864
|
ESR2
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29509190
25604459
|
EED
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23238014
17041588
|
DDB1
|
MBD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22939629
34026424
|
MBD3
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24048479
30415952
|
CDC73
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
26687678
|
MYC
|
TDG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
26496610
|
MYC
|
DNMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MBD3
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
25123934
|
MYCN
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18003922
31856871
|
ESR1
|
KLF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
DNMT3A
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
EZH2
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27634302
26496610
|
CCND2
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
CBX1
|
EHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
H3C2
|
CBX1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
16415788
5218238
|
CBX1
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
16415788
5218238
|
CCNG1
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ESR1
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23403292
17289570
31527615
|
KDM1A
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31130994
23455924
|
HDAC1
|
EHMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26496610
|
PIAS2
|
STAT4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12716907
16189514
|
CBX5
|
EHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
CBX5
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
PTGES3
|
TERT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
HDAC1
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CBX1
|
SUV39H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
BRCA1
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25531315
23624935
|
EZH2
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23238014
27634302
|
MYC
|
TERT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32140074
28628118
28205554
|
ESR1
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
15961505
|
EZH2
|
MYCN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23362253
27728805
|
ESR1
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21984853
31527615
|
ESR1
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
17502350
|
DNMT3B
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
AXIN2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
10911903
|
DAXX
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
EHMT2
|
CBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27705803
19706462
24981860
15200951
17962312
|
H3C2
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
20871592
8087215
|
CBX5
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
16415788
5218238
|
H3C2
|
CBX5
|
â—¼ PROXIMITY
|
✅
|
|
0.85
|
0.85
|
mint
|
25281560
|
CDKN1B
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
34591612
|
CUL4B
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34026424
25189618
|
DNMT1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
ANPEP
|
SFN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
CBX5
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24981860
17962312
20562864
15200951
|
EZH2
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23238014
26496610
|
ESR1
|
PTGES3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
DAXX
|
DNMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CCND1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
EHMT2
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26028330
26751641
|
MYC
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
30415952
29467282
23455924
|
KDM1A
|
MBD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19703393
23455924
21937684
|
PIAS1
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27032383
24654937
19217413
15561718
22578841
16524884
11583632
14609633
18806873
|
HDAC1
|
UHRF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27743347
15361834
21952639
27114453
|
HDAC1
|
EHMT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
23752268
26028330
26496610
33961781
16287849
|
PIAS1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11117529
15666801
31527615
|
UHRF2
|
CCNE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21952639
15178429
|
DAXX
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
ESR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
RB1
|
SMARCA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
KEAP1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
DNMT1
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CBX5
|
SP100
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
DCAF8
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
31973889
33288900
33961781
31155351
21145461
16949367
|
UHRF1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15361834
20037778
17934516
22411829
19800870
31782885
|
MDFI
|
MYOG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8797820
16713569
|
DNMT1
|
EED
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16357870
22094255
|
ESR2
|
NRIP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11500849
21182203
15604093
|
HDAC1
|
SMARCA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
SP100
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
DAXX
|
RASSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
MYC
|
ZBTB17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
ALDOA
|
ALDOC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
CCND2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CCNE1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
NRIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
HDAC1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21102443
10220405
16713569
|
CCND1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17334399
16713569
9244350
|
BRCA1
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26831064
18025037
20016594
|
SP100
|
CBX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11313457
16189514
25416956
32296183
31753913
9636146
21516116
27107012
15882967
|
CDKN1B
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
34591612
|
CUL4B
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23238014
24292684
27634302
|
DCAF8
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32703400
31257023
32235678
33288900
31391242
19966799
33961781
24500646
31155351
16964240
19295130
16949367
|
DDB1
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22118460
20870715
16473935
15448697
16678110
30349055
33504946
16751180
|
HDAC1
|
KDM1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16079794
19703393
21258344
34050636
11102443
27183383
16140033
21937684
12032298
26496610
22143567
19497860
11171972
17634443
12493763
20856864
20585571
31130994
21670149
26344197
23752268
32882276
17687328
33961781
24981860
28667074
|
MBD4
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
10097147
16189514
25358258
|
MYC
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12584560
29467282
|
PIAS2
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17471507
16352593
17418410
18923429
11283613
20426839
30415952
19786833
|
SUMO1
|
SP100
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11313457
16189514
25416956
32296183
16524884
21880768
24654937
15017387
24637324
10212234
17491593
9412458
|
TDG
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12874288
16282588
|
HDAC1
|
SPI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14647463
16331260
11593411
|
DNMT1
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31130994
16357870
22094255
28068325
21378168
|
EHMT1
|
EHMT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
EHMT2
|
EHMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21430779
26028330
27705803
21258344
24981860
34588438
28698370
|
CBX5
|
SUV39H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CBX1
|
TRIM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
AXIN2
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10966653
10911903
9554852
|
ESR1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
1244506
11782371
15674350
29367421
27977889
17392432
16860316
10334989
16260778
11244506
16061635
12400015
17505062
20060929
25499220
16713569
31527615
11493692
|
MYC
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12646176
11916966
16713569
20215511
9788437
30415952
14612409
|
MLH1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10783165
17148452
25184681
16786532
21240188
29656893
|
DNMT1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19943104
22197621
20631324
|
EZH2
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19079346
20574448
|
MYC
|
CBX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
CCND1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16061635
9039267
11073968
|
UHRF2
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21952639
|
MYC
|
CD44
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22002305
22911891
19738061
|
ALAS1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CSAD
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDKN1A
|
SETDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MYOG
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25211658
16351709
|
ESR2
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19487281
14729654
23907131
|
ESR1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17163418
17681750
|
RBX1
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33969670
24292684
12481031
25189618
12609982
26496610
30349055
27113764
29499938
19250909
22038470
34026424
28446751
31973889
23238014
33961781
33504946
30945288
32140073
|
CUL4B
|
DDB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19651607
33969670
33357448
28225217
24292684
25189618
21145461
18593899
26496610
16678110
16964240
33536335
27113764
29499938
30898011
28886238
29738775
17392787
29846670
22939629
22038470
34026424
16949367
31911655
28446751
17041588
23238014
31973889
16861906
33961781
30945288
26344197
32140073
|
SMARCA4
|
HIC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19015639
|
MYC
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314511
18271930
34147029
26496610
30415952
18003922
22286234
24951594
|
TFAP2A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9632747
8276360
7555706
|
RB1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7680889
10200487
9671466
|
MYC
|
MEIS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
AMPD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SFRP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17485441
20697356
|
MYC
|
RARB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12695333
11085504
|
MYC
|
AXIN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19149881
24299953
|
MYC
|
ACADM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
DNMT3B
|
RASSF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19854132
12879017
18006804
|
PIAS2
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
16189514
25416956
11867732
21988832
24654937
16524884
19217413
16204249
14609633
17036045
|
SUMO1
|
TDG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
10961991
21284855
16763556
16524884
15959518
24637324
11889051
17060459
|
ESR1
|
SUMO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15961505
24119295
18404132
|
ESR2
|
TDG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
TDG
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12874288
17129768
|
HDAC1
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18381204
21669397
|
H3C2
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22064703
17673620
22348533
|
UHRF1
|
DNMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20613874
22064703
19798101
33170271
17673620
29691401
19800870
21045206
29268763
33465813
21268065
21745816
24782312
27045799
19943104
17934516
28803780
31322780
27049577
26065575
24368767
|
CDC73
|
PAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
18469135
20178742
15632063
20305087
26496610
15923622
19136632
27462432
22939629
19410543
29774127
21726809
16024656
22863883
33961781
24981860
26186194
26344197
|
IRF9
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8864350
22252317
9218597
|
MBD3
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
10444591
21258344
11102443
12354758
19041848
27068747
26496610
25123934
24048479
21670149
17827154
22939629
23752268
12124384
16428440
33961781
24981860
26344197
|
ESR1
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17312152
31527615
24051437
33731348
14722073
21182205
15557281
18451880
14506733
15140878
|
CA12
|
DAXX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MYCN
|
DBH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20009769
|
DNMT1
|
DNMT3B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24423239
16481298
20155458
|
DNMT1
|
MT1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16329111
22905112
12417732
|
NRIP1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26153859
9115274
16439465
26166704
23403292
33731348
21182203
7641693
9192902
8887632
|
ESR2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29509190
12630920
17991765
21182203
19022902
10706629
19746436
9473491
|
TFAP2A
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10497269
19458056
9850080
|
ESR1
|
CYP2C19
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20675569
|
ESR1
|
APRT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
ZBTB17
|
PIAS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25043018
14704274
22053792
|
CREM
|
APRT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17227776
10628749
8735279
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
APC
|
JUP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
DNMT1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
EZH2
|
EED
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
24981860
|
CBX5
|
TRIM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
CCND2
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
EED
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
PIAS1
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
HDAC1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
MDFI
|
OTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
DNMT1
|
UHRF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
EZH2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
CCND1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
SUV39H1
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
24981860
|
CDKN1A
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
16765349
5218735
|
UBE2I
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5219915
17491593
|
RB1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
6550000
10779361
|
DNMT3B
|
DNMT3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
CCNE1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
PAF1
|
CDC73
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
24981860
|
EZH2
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
21685935
15520282
10581039
24771265
31130994
22439931
26344197
|
PIAS2
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
CCNE1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
PIAS1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
CBX1
|
CBX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17314413
11336697
27705803
24981860
21888893
20562864
|
SUMO1
|
DAXX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11948183
17081986
23395904
18583933
30958586
16475184
12150977
20972456
20927612
25409927
21816224
28851805
21474068
11112409
22578841
31879127
19465479
21383010
|
EED
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10581039
11124122
26496610
22439931
|
DAXX
|
HDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
24550390
12529400
10669754
29084956
32545337
|
HDAC1
|
DNMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
22274925
20613874
26794444
10615135
10888886
17707923
17934516
15870198
21670149
27593931
17967891
12473678
23708667
|
EED
|
EZH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21135039
9584197
9742080
31948940
29379173
27338022
18931660
28068325
33754075
11158321
9584199
32296183
22897849
17937919
19026780
21190999
26496610
24320048
33849069
27634302
15385962
16314526
29669287
15225548
18285464
10581039
21123648
12435631
31786184
23624935
24457600
20075857
15882624
19026781
21078963
22094255
22439931
28320739
27705803
31527584
24981860
33961781
23280602
26344197
|
HDAC1
|
KDM1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
SUMO1
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
UHRF1
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
DNMT1
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
HDAC1
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ALDOA
|
ALDOC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
25416956
31536960
25910212
26496610
22863883
33961781
26186194
22939629
26344197
|
DDB1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
DNMT1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
DAXX
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CUL4B
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
PIAS2
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CCND1
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
CCND1
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
DNMT3A
|
DNMT3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
SUMO1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CUL4B
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
DNMT1
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDC73
|
PAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
APC
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
APC
|
RBX1
|
â—¼ SHARES_COMPLEX
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
APC
|
RBX1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
MYC
|
APC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22911891
12695333
|
BRCA1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
11877377
15175241
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
19793801
20029420
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
RB1
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
11877377
15175241
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
19793801
20029420
21060331
21337561
24254977
7575488
7935440
|
MYC
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12032322
19882681
20940401
10375022
21668996
11916966
12646176
11983916
|
BRCA1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9926942
11394910
10196224
18025037
21245169
16735508
12647291
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
BRCA1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11877377
21060331
19793801
21337561
15459660
20029420
|
CBX1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
15136563
11882902
16622419
20871592
11242053
19111658
15960974
16415788
26527279
|
CBX5
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16687578
16622419
20871592
20011120
25281560
26527279
19111658
16415788
19498464
|
RB1
|
CCND1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
10207050
9447971
24876129
31543423
11416152
11032757
9190208
30711375
10499802
|
KLF4
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
23884787
11005769
23861801
19737957
10908361
21132436
21224073
|
MYC
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7526316
21933022
17881732
12835716
14757441
19086036
8552398
19698176
19786833
18809243
18806825
8196642
11085504
|
ESR2
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15313930
14764652
18607069
23891847
11986316
18223478
14729654
|
ESR1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
11477579
12554765
12808053
17166846
22892083
21505052
18414489
9832502
23864650
22396492
22266855
11358796
23891847
22948256
11986316
15282324
15496458
22521644
14764652
15178330
23108396
11410592
15026472
17998543
17681750
18245487
20821348
16860316
11844790
19858209
12929585
15808510
18997820
15217513
16809759
10500157
16980581
17914104
|
CDKN1B
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17145710
9106657
10908655
17254966
25416956
7478582
|
CDKN1A
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
26203195
23443559
17145710
25416956
7478582
9837900
21988832
21516116
7777546
15232106
16082198
27107012
15695403
8657154
8242751
23007395
9106657
12383116
17556661
8756624
8662825
31515488
|
ESR1
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8649771
11073968
16061635
9039267
|
MYC
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8425218
15121849
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
CCND1
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
10498883
9315635
17303408
16236519
11520855
15279786
9190208
7575488
10385618
9736735
8490963
26225123
19237565
7736585
19075565
18590585
27507850
26121043
20068082
9425340
18786381
17660363
10778858
9380698
27430527
|
CCND1
|
SUV39H1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10385618
9736735
12006580
10498883
|
RB1
|
CDKN1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
10207050
9447971
24876129
31543423
11416152
11032757
9190208
30711375
10499802
|
TFAP2A
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21084835
9473523
16867219
16288208
11420667
18955504
20805990
8988173
17875680
12226108
|
EZH2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21572997
21546904
24074410
21629038
22956625
|
DNMT3A
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20473858
15616584
16131836
24957603
|
MYC
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15190211
14519204
15616584
12408868
19174556
21949397
10319992
12553001
16204065
12545156
20878079
21042278
21400515
20190815
16706751
23804320
15757889
10920185
19270520
16452181
12408820
15528212
22371483
12565816
17885207
12384701
11274368
19150257
20551174
15899785
21120446
15071503
15474507
22814619
12835716
12748190
16738884
15711923
18636159
|
HDAC1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12665570
19182791
15130752
18210215
16287849
17172847
|
KLF4
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10749849
23884787
18483411
21652709
23861801
19737957
21132436
21224073
22750490
21763782
18645021
|
ESR1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15557281
16628468
20696891
16847062
12151347
11517191
15378598
11274368
16469747
17681750
20301197
22787161
23349794
|
DNMT1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21229291
21572997
19056828
16276353
9588214
21868513
23658227
|
MYC
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15528212
9618481
12545156
17550342
10454538
15155580
11283613
10920185
11283614
|
ZBTB17
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9618481
12545156
17550342
17828269
10454538
15155580
11283613
11283614
|
RBX1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11278750
15340381
12820959
15688063
18381890
19440234
|
CDKN1A
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
23443559
26186194
25241761
27107012
8756624
15169570
25416956
16765349
31515488
16189514
32296183
|
CDKN1A
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
10498883
9315635
17303408
10486249
16236519
11520855
15279786
9190208
7575488
10385618
9736735
7736585
19075565
18590585
20068082
9425340
18786381
17660363
10778858
17556661
|
CDKN1A
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
23443559
31831640
21988832
9472014
17293600
11438644
9380407
12839982
16765349
9632134
25241761
8891332
9660939
8242751
9218599
11477082
8756624
8662825
8637717
9716181
13678583
|
RB1
|
CDKN1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
10207050
9447971
24876129
31543423
11416152
11032757
9190208
30711375
10499802
|
CCNE1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
31831640
8978686
8684460
17293600
9632134
17254967
9311993
20837141
27175940
9488039
25241761
8891332
9660939
7753174
19470470
9218599
12529437
9192873
8756624
17254966
12501191
9891079
10393546
9716181
11940657
|
CDKN1B
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
25910212
16189514
|
CDKN1B
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
17145710
31831640
8978686
8684460
17293600
9632134
17254967
9311993
20837141
27175940
9488039
25241761
8891332
9660939
7753174
19470470
9218599
12529437
9192873
8756624
17254966
12501191
9891079
10393546
9716181
11940657
|
MYC
|
CDKN2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
9308237
10373560
17936558
12738781
17873522
11283613
21406394
9312026
17093053
15095404
17558397
20551172
19901969
19815509
10504341
|
MYOG
|
CKM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8393137
2163343
8262151
1313772
15930130
23732671
|
RBX1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
RBX1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19270156
19440234
19557001
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
RBX1
|
DDB1
|
â—¼ SHARES_COMPLEX
|
|
|
27.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18381890
18931676
19270156
19440234
19557001
19622404
19686080
19809470
19847258
20211143
20457011
22257761
22373527
22615860
22824526
23085398
|
UBE2I
|
HIC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
23417673
27935866
20547755
17283066
|
SUMO1
|
HIC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
23417673
27935866
20547755
17283066
|
KDM1A
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17277772
24371278
19098913
18187655
|
KDM1A
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17277772
24371278
19098913
18187655
|
KDM1A
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16223729
20210320
18343668
20228790
15620353
|
RBX1
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
RBX1
|
KEAP1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15340381
15459660
15688063
15703371
16697054
17312394
17884153
18931676
19560419
19622404
19686080
19809470
19818716
19847258
23030059
23850759
|
MLH1
|
MBD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
10545939
12417741
12584560
14614141
15242590
15375219
15377654
15485915
15703371
15814658
16612326
16697054
16713580
16818604
17855402
18157157
18406444
18543256
18995830
19686080
19847258
20478261
|
MLH1
|
MBD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
10545939
12417741
12584560
14614141
15242590
15375219
15377654
15485915
15703371
15814658
16612326
16697054
16713580
16818604
17855402
18157157
18406444
18543256
18995830
19686080
19847258
20478261
|
MYC
|
VEGFA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
PIAS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21811581
22053792
12545156
17471507
|
MYC
|
CCNE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18802399
20607601
14519204
22583478
9188852
11983916
11509615
|
MYC
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7526316
11511535
10508165
9339900
15988028
20857481
11060032
14519204
14660677
10956386
21790895
11264343
|
MYC
|
CDKN2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
12244100
22610535
11804592
12565816
19164764
12835716
11283613
14519204
24618291
19201832
23722468
|
MYC
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
76.0
|
1.0
|
Omnipath
|
16287840
15655249
12821782
16880523
21807113
19047367
14744757
16489011
12941894
10786671
14519204
19360348
10723141
12970752
15595642
18365874
15665468
22207128
14611815
10022128
15226182
11274400
10491298
11606399
17070091
19787269
19806010
20454512
19762557
21132266
21553143
18818322
10914736
17934056
19148473
11435602
12695333
12802280
21995449
11287602
12044867
21627565
23860446
17942561
19649288
23759068
10606235
12807729
15958520
17141225
20723213
16402390
16785237
18093727
21855630
24705139
18367227
14563552
16205635
19003324
9988278
17706770
17967894
18226852
18754863
10637317
18586674
14612409
19912441
15371341
11916966
12646176
11279234
18158869
|
MYC
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19738061
19147754
17785433
22002305
18809243
19398483
12368264
23028984
|
MYC
|
TGFB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9196027
12695333
|
HDAC1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
MYC
|
CCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8425218
15121849
11602341
2006410
17873522
21406394
12584560
17558397
20551172
15814658
16908182
|
MYC
|
ZBTB17
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
17145710
26766587
18923429
29137325
20426839
11283613
17418410
9312026
20697356
19786833
16352593
|
MYC
|
CDKN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
10454538
10373560
9308237
17936558
12738781
17873522
11283613
21406394
9312026
15095404
10504341
17558397
20551172
19901969
19815509
11283614
|
RBX1
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
SMARCA4
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9099865
18451880
11003650
|
SMARCA4
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19571879
24550003
|
TFAP2A
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
12072434
24835590
25114211
21375726
|
SUMO1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11960997
12032081
15199155
24068740
|
UBE2I
|
SUMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
21212807
25416956
16713569
18691969
17938407
11735126
25502805
15931224
26496610
16732283
24352468
17353931
18359863
10666456
21174150
8921390
9353268
12924945
21949651
32296183
16524884
17956732
18264111
12764129
10961991
14673145
19684601
17698038
16494873
31515488
23871147
17491593
|
PIAS1
|
SUMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16524884
22578841
19217413
18806873
14609633
11583632
|
PIAS2
|
SUMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16204249
21988832
25416956
19217413
16189514
14609633
16524884
12764129
|
SUMO1
|
TDG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
16763556
15959518
17060459
21284855
20504299
16189514
16524884
11889051
10961991
|
CCND2
|
SUV39H1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10385618
9736735
12006580
10498883
|
SUV39H1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16409643
19442252
11242053
10949293
|
UBE2I
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15823533
18691969
21284855
15959518
11889051
|
UBE2I
|
TDG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18512959
24753249
18691969
|
ESR1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21411498
12122114
21693539
18519947
16690106
10805720
19360348
23409030
18754863
|
ESR2
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12122114
10805720
|
UBE2I
|
TRIM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
17942393
17079232
25114211
18488044
17298944
18082607
|
TRIM28
|
SETDB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11959841
|
UHRF1
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19798101
22064703
20210320
17673620
24368767
19800870
27049577
20613874
21268065
24782312
26065575
17934516
21045206
21745816
19308066
27045799
|
MDFI
|
MYOG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
8797820
16713569
|
HDAC1
|
AXIN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21734722
17666529
15576399
22761862
22290435
19923891
20682799
|
HOXA9
|
MEIS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10082572
15161102
9343407
|
VEGFA
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
VEGFA
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
TFAP2A
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11191053
16790435
11731421
9049304
12570801
14744778
8466753
11007955
23506169
|
ESR1
|
VEGFA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16267616
12400015
17272396
18252963
18497067
10866309
19420388
19398483
16249470
14647449
15774498
12208749
10995484
|
STAT4
|
IFNG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10807786
10961885
11449378
12372421
8683106
8700208
9715265
|
IFNG
|
FOXP3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
FOXP3
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20554955
17028180
23543754
19877017
17377532
20308632
|
SPI1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15345588
19502584
12130529
7814871
9545284
20585034
|
EZH2
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22563434
21674483
17911618
21624129
|
STAT4
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12759422
12902482
14734615
19359411
23761633
15251440
20620946
11449378
12594853
12893768
10097133
20574006
25589075
19710469
11801649
26123499
15522880
9558063
9642277
16717115
24415943
17110450
16301617
|
UBE2I
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11960997
12032081
15199155
24068740
|
HDAC1
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
15465827
17018611
17563753
21234400
21577210
21685935
22514743
22796940
|
HDAC1
|
EZH2
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
15465827
17018611
17563753
21234400
21577210
21685935
22514743
22796940
|
HDAC1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21655924
23242655
18316616
20101232
|
UBE2I
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12820959
15340381
11960997
|
ESR1
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15208657
16029657
19440537
14991571
18669446
17932106
|
PIAS2
|
STAT4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
12716907
16189514
|
DNMT1
|
FOXP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19454658
32905139
23687305
19109157
|
KLF4
|
ARG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10432118
10925299
12193690
21093321
21670502
23390297
6357187
|
PIAS1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15666801
11117529
|
RB1
|
CCND2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
10207050
9447971
24876129
31543423
11416152
11032757
9190208
30711375
10499802
|
CCND2
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
10498883
9315635
17303408
16236519
11520855
15279786
16326706
9190208
7575488
9003781
10385618
9736735
7736585
19075565
18590585
20068082
9425340
8449399
18786381
17660363
19651622
11254678
8343202
10778858
|
DNMT1
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16357870
24074865
23326524
12435631
22466170
|
DNMT1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21655924
20946668
17172825
15746193
22975348
12789259
19001520
24058781
23242655
22558281
|
ESR2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
14754635
24284820
15207704
18784357
11566442
12630920
22820289
19001520
18511514
14676837
19207817
22622808
21763263
18339713
15087130
|
ESR1
|
NRIP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20200160
10379892
16391242
22071320
18414489
|
NRIP1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9192902
23331499
8887632
9115274
7641693
26166704
12554755
26153859
21182203
16439465
|
ESR1
|
ESR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12630920
9473491
19746436
21182203
10706629
10022879
|
EED
|
EZH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
H3C2
|
DNMT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16357870
24074865
23326524
12435631
22466170
|
EHMT2
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19308066
|
DNMT3L
|
DNMT3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11934864
25383530
15105426
12777184
15861382
17687327
|
H3C2
|
DNMT3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
19834512
21979949
16829525
15861382
17687327
|
H3C2
|
DNMT3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16357870
24074865
23326524
12435631
22466170
|
EHMT2
|
DNMT3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19308066
|
EZH2
|
RRP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24737471
19502792
21546904
22563434
|
EZH2
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18022353
15196462
|
PRMT5
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22231400
20084102
15670829
|
UHRF2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15178429
21952639
|
CCNE1
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
7575488
18590585
9315635
17303408
17660363
12006580
11420722
15279786
|
EHMT2
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19690169
17194708
22387026
|
TFAP2A
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11835395
9632747
21850486
9776742
|
EHMT1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20084102
19010785
20118233
|
SETDB1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21243721
11791185
11252719
11959841
|
TFAP2A
|
DBH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9763470
7616204
11146001
|
ZBTB17
|
CDKN2B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12244100
19419955
19164764
11283613
24618291
15095404
22000024
|
ZBTB17
|
CDKN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
10454538
9308237
17936558
11283613
9312026
15095404
19901969
19815509
11283614
|