Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KPNA2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9497340 6547667
BRCA1 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008167 19146767
YY1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21666725
SMAD3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768112 15735739
CBX3 ADNP â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 36950384
NSD3 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NSL1 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARFGAP3 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBX5 TMCC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CBX5 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBX5 GNAO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YY1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19566924
CBX5 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19111658 16127177
DDB1 CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
RBX1 CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
CUL4B CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
MAD2L2 CHAMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8091839 21063390
ZBTB7A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17189472
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
MYC TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11139609
MYC DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15616584 19786833
MYC KPNA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 35044719 17093053
NIPBL MAU2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0040242 16802858
TAL1 NKX3-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20855495
AR NKX3-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8943214
PARP2 ZNF747 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
TAL1 RBBP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
RCN2 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMARCA4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7914327 20224553
SMARCA4 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SUMO1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
SUMO1 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUV39H1 ZNF829 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 WIZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DNMT1 SUV39H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17172825 17584191
SUV39H1 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
UBE2A KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XRCC6 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H3-4 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
YY1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8990171 10804019
LRIF1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CHD3 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
BAP1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9528852 19117993
BARD1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KPNA2 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMAD4 HDLBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 CEBPB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12202226 5215691
SMAD4 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12150994
TIMM50 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ZBTB16 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
KDM2A SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
UBE2I HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
TAL1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
HDAC2 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
TIMM50 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BCL7A RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KMT2A RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19219072
KLF11 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15531587 15024015
SP1 TAL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8058326 9786909
PPP2CA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24382322
RB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10850422 7732011
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
NSD3 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
UBE2I MBD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17066076 16757475
UBE2I H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
PPP2R5A PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8287037 7592815
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
TBP SUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9512709 9792714
TBP BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9303434 9388207
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
STAT5A DNMT3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26059451
TAL1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
TAL1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
LRIF1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PMF1 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DSN1 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZWINT KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCAP KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TAL1 BCL11B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
TAL1 RB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
ZBTB7A RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18801742 23727861
SUV39H2 WIZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
LBR H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LRIF1 SETDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
BRCA1 SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19768112 15735739
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
PPP2CB PPP2R5A â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
SRPK1 LBR â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19674106 14701833 10390541 10049757
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
HIST4H4 L3MBTL1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HIST1H1E HIST4H4 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ATRX XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30585729 23329831
ORC2 BRCA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17525332 25184681
MYC CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 MIS12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 SCAI â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 WIZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 DSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 PMF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX1 EHMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
MYC CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MECP2 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22615490
SGOL1 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 18716626
CBX3 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24981860
CBX3 TFDP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX3 NSD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20936779
CBX3 AHDC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
DNMT1 CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17470536 12867029
CPLX4 CBX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CBX5 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
CBX5 MECP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22615490 17698499
CBX5 WIZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 20562864
CBX5 BAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27107012 34591877
CBX5 AURKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20231385 20562864
CBX5 EHMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 20562864
CUL4B RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
MYC RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC LBR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC POGZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
XRCC6 PARP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RBX1 ELOC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33504946 12149480
ESR1 RCN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
CHD4 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 20926688
MECP2 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SUMO1 ZBTB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 24654937
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
CHD3 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 30585729
XRCC6 BARD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15782130 22990118
BARD1 AURKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19176389 22350409
HDAC2 ZBTB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26949739 33301849
SP1 MECP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15109260 20385708
PCGF6 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 12167161
BMI1 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26487511 31527615
CHAF1B RBBP4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DDB1 HIST4H4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ACTL6A HIST4H4 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CBX5 ZNF280C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
HIST4H4 KMT2A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CBX3 CHAMP1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CBX1 AHDC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 20850016 27705803
CBX3 PMF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
CHD1L XRCC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23926104 19661379 19666485 28514442
CHD1L PARP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 19666485
MYC PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 29467282
RBBP7 ZBTB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 33301849 26186194
TAF4 SP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11988536 9742090
UBE2A UBE2B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 25582440
XRCC6 ORC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15910003 31160578 30585729
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
NSL1 PMF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 21199919 33961781 24981860 26186194
HIST4H4 SMARCA4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 PCGF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CHD4 SMARCA4 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX1 SUV39H1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CBX5 ATRX â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15882967 10699177 20110566
CBX1 CHAMP1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CBX3 LRIF1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
SUZ12 DDB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23238014 27634302
NSD3 MYC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31638140 28628118 28205554
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
ESR1 SUMO1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 15961505
CEBPB SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16651265 12847250 12665574
CHD4 CHD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28977666 32744500 24981860 22939629 9885572
ASXL3 BAP1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CHAF1A RBBP4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST3H2BB HIST4H4 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CBX3 CHAF1A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SMARCA4 SP1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
BRCA1 WRN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16714450 24709898 29656893
NIPBL CBX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 15882967 20850016 28167679
BARD1 CBX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30874560 32347575 25634209
CUL4B HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 34026424 25189618
ESR1 RBBP7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18577416 23403292 21182205 31527615
SUMO1 WRN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16524884 15355988 19596686
SMAD3 CEBPB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12202226 12524424
RBBP4 SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 12091390 12943729
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
MAU2 NIPBL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
BRCA1 WRN â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CBX1 CHD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28977666 21888893
CBX3 ZMYM3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 27705803
CBX3 XRCC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21888893
CBX3 ZNF8 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21888893
CBX5 SCAI â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27705803 20562864
CBX5 RLF â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27705803 20562864
CBX5 NIPBL â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15882967 20562864
MYC TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15723054 8755740
RARA SUMO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15171703 24819975
SUMO1 MBD1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17066076 24654937
SUMO1 CEBPB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20194620 18820298
WRN XRCC6 â—¼   PHOSPHORYLATION ✅ 0.86 0.86 mint 10783163 5212534
HDAC2 RCOR2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23752268 21258344
NSD3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25640309 31527615
ESR1 RARA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9717844 25303530 25604459
CHD3 TAL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15383276 19497860
CHD4 HIST4H4 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
SP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14710355 16713569 12706836 10720440 17766039
PCGF6 CBX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
POGZ CBX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20850016 27705803 24981860 21888893 20562864
NSL1 CBX1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20231385 24981860 27705803
CBX1 ADNP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 21888893 27705803 24981860
CBX1 ADNP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 21888893 27705803 20850016
CBX1 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20850016 27705803 24981860 21888893 28977666
BAP1 CBX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32509391 19615732 34591877 29686263
CBX3 EHMT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
CBX3 SENP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
CBX3 RLF â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
CBX3 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 21888893 24981860 28977666
CBX3 WIZ â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
LRIF1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 21900206 2001699 8089645
CBX5 ADNP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 24981860 21888893 20562864
CBX5 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32744500 27705803 24981860 15882967 28977666
CBX5 PMF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 20562864 24981860
CBX5 AHDC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 20850016 20562864
CBX5 SENP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 20562864 24018422
CUL4B SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 27634302
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC SMC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC ADNP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
SUZ12 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 35016035 26186194 24981860 12435631 27634302 24457600 31281901 20075857
BAP1 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32509391 19615732 34591877 29686263
PCGF6 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
HDAC2 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HDAC2 ZMYM3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12493763 28242625 21258344
HDAC2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 26344197 20075857
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
ZWINT NSL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20360068 21199919 26496610 20231385 33961781 24981860 26186194
ZWINT PMF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20360068 26496610 33961781 24981860 26186194 15824131
PCGF6 TFDP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
PCGF6 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
CBX1 CHD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RB1 SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DSN1 PMF1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBX1 CHAF1A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CHAMP1 MAD2L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAD2L2 POGZ â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7A SMARCA4 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CBX5 DSN1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CBX5 NSL1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BCL7A SMARCA2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ZNF552 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MGA PCGF6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CBX5 MIS12 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRCA1 CBX3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 23074186 25634209 25184681
MIS12 CBX3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15502821 33961781 27705803 24981860
CHD1L XRCC6 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CHAMP1 POGZ â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
SP1 SUMO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18239466 18572193
TAL1 HDAC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16407974 19497860
HDAC2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17312152 18059533 16713569 15713621 17894944 12091390 16036112 12151407 21159880 12176973 20697349
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
WIZ EHMT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26344197 16702210 26496610 24981860
CBX1 ZNF280C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
H2AFX HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CBX3 ZNF280C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PMF1 ZWINT â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBX5 CHAF1B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CSNK2A1 HDAC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RBBP4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10220405 16713569 26831064
HDAC2 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21946536 10220405 16713569
BAP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9528852 23850490 16713569
BRCA1 SUMO1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
CBX1 LRIF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 24981860 23542155 16169070
POGZ CBX3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20850016 27705803 33961781 21888893 24981860 34079125 20562864
DSN1 CBX3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15502821 27705803 33961781 24981860 34079125
CBX3 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 12004135 22325352 33961781 24981860
CBX3 NSL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 20231385 24981860 21888893 34079125
CBX3 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 28977666 21888893
CBX3 ADNP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20850016 29795351 27705803 33961781 21888893 24981860 32533114 34079125
CBX3 LBR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 8663349
DSN1 CBX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15502821 26496610 27705803 20231385 33961781 24981860 26186194 20562864
CBX5 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 24981860 21888893 15306854 15882967 20562864
CBX5 SGOL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21346195 18716626 20231385 24981860 20562864
CBX5 POGZ â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20850016 27705803 24981860 20562864 19498464
CBX5 LRIF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21900206 32296183 23542155 27705803 24981860 20562864
DDB1 RBX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22118460 20870715 16473935 15448697 16678110 30349055 33504946 16751180
MYC SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11274368 18003922 17418410 15780936 32115405
MYC XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
MYC CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
RB1 RBBP7 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CHD3 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 28977666 27705803 33961781 26186194 22939629
CHD4 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 9790534 25247294 33961781 26186194 28977666
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
SP1 SMAD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10878024 18215124 21297662 16714330 11114293 22033265
SMAD4 CEBPB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12202226 16959612 12524424
SP1 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11432852 10878024 12228247 22227581 16714330 11114293
HDAC2 DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23708667 17967891 21670149 10888872
RARA SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 19401466 16713569
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
CHD4 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9790534 28977666 27705803 32744500 33961781 24981860 21670149 22939629 9885572 26344197
CHD3 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28977666 27705803 33961781 24981860 22939629 9885572
DSN1 PMF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15502821 26496610 27705803 33961781 24981860 26186194 20404110
DSN1 ZWINT â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 20360068 15502821 26496610 27705803 33961781 24981860 26186194 15824131
CBX5 SUV39H1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
H2AFX XRCC6 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CBX5 CHAF1A â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
RPL26L1 RPL5 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
NSL1 ZWINT â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
DSN1 ZWINT â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MIS12 PMF1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
RBBP7 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11394910 10220405 16713569 11746496
MYC BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12646176 11916966 16713569 20215511 9788437 30415952 14612409
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
SGOL1 CBX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24981860 21346195 18716626
CBX1 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 27705803 33961781 21888893 24981860 34079125
CBX5 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 20850016 27705803 20231385 33961781 21888893 24981860 15306854 34079125 20562864 19498464
ADNP2 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 27705803 33961781 21888893 34079125
CBX3 LRIF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 23542155 27705803 33961781 21888893 24981860 34079125
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CBX3 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19111658 16127177 17540172
NSL1 CBX5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15502821 27705803 32814053 20231385 24981860 20562864
MIS12 CBX5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15502821 21199919 27705803 20231385 24981860 20562864
CBX5 LBR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15882967 16189514 8663349
CBX5 MBD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12697822 12711603 16713569 19498464
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CSNK2A1 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21245376
RBX1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33969670 24292684 12481031 25189618 12609982 26496610 30349055 27113764 29499938 19250909 22038470 34026424 28446751 31973889 23238014 33961781 33504946 30945288 32140073
CUL4B DDB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19651607 33969670 33357448 28225217 24292684 25189618 21145461 18593899 26496610 16678110 16964240 33536335 27113764 29499938 30898011 28886238 29738775 17392787 29846670 22939629 22038470 34026424 16949367 31911655 28446751 17041588 23238014 31973889 16861906 33961781 30945288 26344197 32140073
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
TFAP2A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9632747 8276360 7555706
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
MYC MBD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RPL26 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 11085504
MYC RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC LBR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
RBX1 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 23401859 33567268 12048197 17353931 15601820 26735018 24469044 30349055 33504946 33137104 12604794 16261165 16325183
VHL SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20844582 24002598 20300531
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
TBP TAF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8858156 19240132 9603525 10373431 9674425 9153318 22323595 22939629 17967894 12665565 9311784
WRN XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12177300 11328876 26496610 14734561 33961781 10880505 10783163 30585729
ESR1 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17275994
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SP1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21421563
SMAD4 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278818
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
RARA SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
SMAD3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12202226 12524424
HDAC2 CHD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12198550 23752268 22939629 9804427 30737378 28977666 26949739 24981860 17827154 12493763 9885572
HDAC2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 9790534 9804427 11003653 22939629 30737378 28977666 26949739 32744500 21258344 24981860 21670149 12493763 9885572 10545197 26344197
AURKB ZWINT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775627
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
VHL UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20844582 24002598 20300531
ELOC VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 28514442 9751722 10205047 7660130 10823831 15060148 21942715 12604794 9122164 14636579 15611064 19030229 21685897 17558023 10635329 32328410 10421634 28775317 15601820 10449727 17922844 20871634 24469044 10587522 25500545 8674032 22234250 20300531 17353931 17986458 11739384 17244529 26751167 29401731 18323857 25661653 30890701 33137104 7660122 15935760 12697815 18187417 30267325 12004076 26735018 27517496 24981860 33961781 18305400 29121446
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
TBP PMF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
RARA ZBTB16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24821728 21949697 11106752
MIS12 NSL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15371340 20360068 15502821 21199919 26496610 20231385 33961781 24981860 26186194
DSN1 NSL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15502821 26496610 27705803 20231385 23334297 33961781 26186194 24981860 20404110
MIS12 PMF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 15371340 25416956 20360068 15502821 21199919 26496610 33961781 24981860
DSN1 MIS12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15371340 20360068 15502821 21199919 26496610 27705803 23334297 33961781 24981860 26186194 20404110
ZWINT MIS12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15371340 20360068 15502821 21199919 26496610 33961781 24981860 26186194 15824131
SUV39H2 LRIF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
RB1 RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CBX1 POGZ â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ABCE1 RPSA â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CBX1 SGOL1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CHD3 RBBP7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PPP2CB PPP2R5E â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHD4 RBBP7 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 RBBP4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
RPL26 RPSA â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
WRN XRCC6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SUV39H1 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
PPP2CA SGOL1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ACTL6A SMARCA2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ESR1 NR2F1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
BARD1 BRCA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12431996 17525341 29367421 27977889 19916563 12732733 10477523 20060929 23680151 8944023 22110403 12951069 23086937 14638690 27239795 29355525 9788437 11925436 11257228 24289923 14647430 19176389 15184379 9738006 16403807 29180510 11278247 33589814 15265711 15159397 34408138 16713569 19117993 20681793 16391231 11301010 16489000 23416467 17664283 15569676 29858377 19369211 18493658 29656893 20351172 28398198 12485996 32347575 19766185 14636569 10026184 12700228 31270457 11573085 11526114 24085845 25823446 33961781 32092106 18936166 28514442 20215511 25184681 26490435 28948225 12890688 12438698 28262780 26831064 9342365 10635334 15855157 11504724 11773071 25252691 9798686 26350354 21901007 24695549 12887909 17873885 11498787 27454289 11927591 24981860 25652403 25634209
CBX1 CBX5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17314413 11336697 27705803 24981860 21888893 20562864
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SUZ12 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 15225548 27705803 33961781 35016035 24981860 27634302 22939629 24457600 31281901 20075857
CBX3 HIST1H1E â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
MIS12 ZWINT â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RB1 TFDP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
DSN1 NSL1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RPL26 RPL5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL5 RPSA â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
DSN1 MIS12 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MIS12 NSL1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTL6A SMARCA4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TAF4 TBP â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBBP4 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2CA PPP2R5E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AR ABCE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP2 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
BRCA1 RB1 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP2 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
BAP1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 9528852
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CSNK2A1 CBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19657222
CBX1 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19111658 16127177 18438399
POGZ CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 27705803 20850016 20562864 19498464
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
CHAMP1 MAD2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21063390 20850016 26496610
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
PPP2R5A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
PPP2CB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16987807 16680151 15048125
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PPP2CA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151 15048125
ZBTB16 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14645547 19723763 19444914 18246121
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
NKX3-1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18360715 20363913 23492366 17202838 16697957
WRN PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
WRN PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
RBBP7 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBX1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 ULK3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16611981 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258
RBX1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11359933
AR SMARCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 17721441
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
TFAP2A SUMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12072434 24835590 25114211 21375726
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SUMO1 ZBTB16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17498654 18348865 14527952
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
WRN BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
WRN BMI1 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11283614 12202749 12545156 15155580 15385537 16449207 17055429 17116323 17550342 17965729 18398454 18524993 18558713 18584027 18809224 19490890 20027199 20064462 20691907 20713526 20818389 21376743 21733352 2191300 21919891 22657828 22743550 23082994 23140366 23161013 23253856 23869868 24036544 24050180 24709898 9618481
XRCC6 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
TAL1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17306248 12569129 18809240 19029143 11049987 12799070
SP1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19888537 14684628 15111490 12560084 19469899 21980525 16678129 18006642 9079666 12067897 21430706 16574784
ESR1 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16574784 18006642
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278818 11331591
PPP2CA SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20704570 23331499 19951945
CDK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
CSNK2A1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 19007248 16565220 20166139 17081983 20230923 25609639 19413330 19415658 20388487 20068231 18452278 18669648 18691976 17287340 12176973 19651622 12082111 19691289 24526703 18510355 18212344
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27496133 27933271 19225156
AURKB DSN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20471944 25601404 27881301 25660545 18640974
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
ESR1 RELB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17369819 20034404 19433448
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 ZBTB7A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19444642 23027183 19723341 18368381
SP1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18801742 12760745 8007947 1588949 17384411 21465530 15618023 7896792
SP1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19750005 19420015 12076969 21420382
SP1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11684680 8055923 12700237 21820092 8910434
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15713650 16772287 16720721 18843047 11668178
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
PPP2CA PPP2R5A â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PPP2CA RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10921877 21159657 16885030 12370081 19890961 16916641 10702384 21376459
CSNK2A1 TFAP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21777522
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
AR ZBTB16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15334066 20610535 16637071
SUZ12 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RBBP4 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
TFAP2A RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11835395 9632747 21850486 9776742
MBD1 SETDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15691849 15327775 17066076
MBD1 SETDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15327775 17066076