Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CEP170P1 AIMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
FUBP1 AIMP2 â—¼   COLOCALIZATION 2.0 0.8 intact 8145365 21285945
STAT5B BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16819511 15711548
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
ELAVL1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19010922
STAT5A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003515 21038417
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
ELAVL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19884656
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
MYC PMAIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18042711 22216287
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
PUF60 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20420426
MYC PMAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15856024
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
USP22 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8296194 21779003
VIM PUF60 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
VIM CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
BMI1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 19903340 8291464
PTEN BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19903340
STAT5B CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11160217 12586844
IKZF1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19124715 18941217
FUBP1 CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHD3 PUF60 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PUF60 FUBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TAL1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900437106 19497860
CHD3 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TAL1 FUBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30653565
CELF1 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TLE1 FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GATA3 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19674970 11397697
GATA3 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25303530 22120723
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MDC1 MDM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14578343 18471438
MYC U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RBM15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29467282 26496610
BMI1 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
U2AF2 FUBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 26641092
U2AF2 ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26641092
VCAM1 FUBP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 FUBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
FUBP1 CELF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 16169070
FUBP1 ANX11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 26344197
VCAM1 ELAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MATR3 FUBP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 ELAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29395067 29884807
ELAV1 BMI1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24457600 19322201 34316702
ELAV1 FUBP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29395067 31553912 19322201
CHD3 TAL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15383276 19497860
TAL1 GATA3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21179004 9819382
CUL3 ARMC5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 33130828
FUBP1 FUBP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 33961781 26344197
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
PUF60 U2AF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
CHD3 IKZF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10204490 30760870 33961781
FUBP1 SMN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10734235 19928837
MATR3 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AIMP2 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FUBP1 AIMP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21988832 21285945 12819782
ATF2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23800081 10506225
MYC BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12646176 11916966 16713569 20215511 9788437 30415952 14612409
VIM CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
OTUB1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
MKI67 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
MYC PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
U2AF2 PUF60 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16189514 25416956 16713569 10866799 17353931 22365833 16169070 22939629 26344197
PUF60 FUBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29997244 20711187 10882074 32296183
SMN1 TLE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
TAL1 GATA1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 7568177 16407974
ELAV1 CELF1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 29395067 26344197 19322201
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
FUBP1 PUF60 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ATF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20068037 15356147 11490006 10748079 12509451 10688670 10318823 10913190 10954918 16888805 15546613 20018859 9826775 8816436 8552071
STAT5A BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16819511 15711548 20498019 20124477 23716595
BCL6 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19337254 18648506 15509806 22723377 17392284
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
BRCA1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9926942 11394910 10196224 18025037 21245169 16735508 12647291
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
CCNH GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDKN1A CCNH â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND2 CCNH â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
ELAVL1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19528229 18519672
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
ELAVL1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18519672 19574298
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
MYC CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7526316 11511535 10508165 9339900 15988028 20857481 11060032 14519204 14660677 10956386 21790895 11264343
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MYC CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12244100 22610535 11804592 12565816 19164764 12835716 11283613 14519204 24618291 19201832 23722468
MYC HNRNPA2B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 20010808 12695333
FUBP1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15502847 2191300 18490439 19219071
MYC CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8425218 15121849 11602341 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10454538 10373560 9308237 17936558 12738781 17873522 11283613 21406394 9312026 15095404 10504341 17558397 20551172 19901969 19815509 11283614
TNF MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
KIT STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
GATA1 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27858941 20405120 9345037 16024808
KIT STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10358045
KIT STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10358045
STAT5A CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11160217 12586844 14660677 15509806 22723377
PUF60 FUBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10882074 20420426 20711187 11239393
GATA1 TAL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9786909 1396592 7632958 7678994 8058326