Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
CDK2 MCM6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
PML CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10356361 16007146
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
TADA3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707411 16713569
KAT6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
CEP126 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KAT7 CEP126 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KAT7 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KAT7 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
ING5 PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
ING5 TADA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
ING5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 12750254
TP53 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14636569 15782130
ING5 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CEP126 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KRTAP10-7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ING5 KXD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ING5 GCSH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CEP126 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ING5 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
VIM BRD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM INCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MCM6 MCM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3C2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BEX3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP126 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
DEUP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MEAF6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARFIP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H2BC9 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CEP126 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PRMT5 ING5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
H2BC9 ING5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NAV2 ING5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PCM1 ING5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ING5 CEP126 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CEP126 BRD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H2BC9 KAT6B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HIST1H3J HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3I HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3E HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3B HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3G HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3H HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HIST1H3F HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CDK2 P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 12064478 10747897 19556892 10348343 10884347
HIST1H3A HIST1H3F â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ING5 MCM4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16387653 33961781
PCM1 ING5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 33961781
TADA3 TP53 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HIST2H3A MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
H3F3A MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HIST2H3C MCM2 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ING5 KAT6B â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
JADE1 MEAF6 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
H3F3B ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3D ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3F3C ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3J ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST3H3 ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
H3F3A ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3C ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3H ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3D ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3A ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3PS2 ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3A ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3E ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3I ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3F ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3G ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3C ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST1H3B ING5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
KAT6A EAF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 18794358 33961781 24981860
BRPF3 MEAF6 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
NAV2 ING5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 33961781 25416956
ING5 BRPF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16387653 33961781 31753913 24981860
ING5 JADE3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16387653 33961781 24981860
ING5 JADE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22144582 16387653 33961781 24981860 19187766
BRD1 EAF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27142060 33961781 31753913 24981860
EAF6 BRPF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 31753913 24981860
EAF6 JADE3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
EAF6 KAT6B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
JADE3 KAT7 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
BRPF1 HIST1H3J â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST3H3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST2H3C â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3H â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3D â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST2H3A â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3E â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3I â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3F â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3G â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3C â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRPF1 HIST1H3B â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST1H3B KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
H3F3A KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3D KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3H KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3I KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
H3F3B KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3J KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST2H3PS2 KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST2H3A KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3G KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST2H3C KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3C KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3F KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HIST1H3E KAT6A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
KAT7 JADE2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27270040 16387653 33961781 24981860 26186194 30833792
KAT7 ING5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 17954561 27270040 16387653 33961781 24981860
KAT7 EAF6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27270040 16387653 33961781 24981860
KAT7 JADE3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27270040 16387653 33961781 24981860
KAT7 BRD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27142060 27270040 31753913 33961781 24981860
KAT7 BRPF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27270040 31753913 33961781 24981860
PRMT5 SMARCE1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ING5 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 17954561 21177815 12750254
BRD1 MEAF6 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ING5 KAT6A â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HIST1H3B HIST1H3J â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BARD1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EP300 MCM4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 MCM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
BRPF1 EAF6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 18794358 33961781 24981860
H3F3B HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3B HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3C HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3J â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3E â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3F â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3I â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3H â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3B â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3C â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3G â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HIST1H3A PRMT5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
H3F3B HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
KAT7 JADE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 18684714 24739512 22144582 27270040 16387653 33961781 29382722 26186194 24981860 19187766
HIST1H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3D â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3J HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3PS2 HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3H HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3D HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3A HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3F HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3I HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3E HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H3G HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
MCM6 ING5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16387653 16189514 33961781
ING5 JADE1 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
ING5 BRD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27142060 31753913 16387653 33961781 24981860
ING5 EAF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18794358 16387653 33961781 24981860
JADE2 EAF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 24981860 26186194 30833792
H3F3C KAT6A â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HIST2H3D KAT6A â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MIS18BP1 OIP5 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HIST2H3D HIST3H3 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HIST1H3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KRT40 SUOX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HIST1H3J HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ING5 BRPF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 18794358 16387653 33961781 24981860
JADE1 EAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22144582 33961781 29382722 24981860 19187766
KRT40 OIP5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BRPF3 KAT7 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ING5 JADE2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BARD1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14636569 15782130 26022179 21742769
ING5 JADE2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 16387653 33961781 24981860 26186194 21516116 30833792
CDK2 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 10330164 23455922
CDK2 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15855157 15665273 31270457
VIM CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ING5 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT7 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22713239 20123734 12609999
EP300 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9809062 15295102 21471221 26229107 15337767 23010591 18485870 15558054 22266186 15509808 26625199 9194564 23402884 23870121 17438265 16959611 12690203 17906639 24821727 15664194 21187340 33196849 17977830 11804596 25288747 15186775 18612383 23796514 19234109 27818144 19339993 24157709 9652736 28757384 12499368 17452980 9891054 23880760 31167125 15542844 22013068 16713569 9288740 17189186 11782467 16543236 23329847 10942770 26302407 23307557 22074660 19218448 19217391 10601022 16024799 16782091 12501250 11433299 22731250 23728348 10518217 9194565 25651062 12724314 14612423 16611888 19805293 18243116 32807901 29706626 20234175 16678111 14759370 25867071 25156994 11907332 16438982 16135789 11070080 11359905 25753752 16537920 9744860 18391200 15965232 10490106 16928824 12162806
VIM KAT7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KAT7 H3C2 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
P53 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 22869143 16713569 12915590 14976551 16007146 20972456 12006491 15375079 11025664 11704853 11080164 21057547
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
VIM FAM118B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
H3C2 MEAF6 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
ING5 TAF1D â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FAM118B ING5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MEST ING5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
H3C2 ING5 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
H3C2 JADE1 â—¼   ACETYLATION ✅ 3.0 0.9 Reactome 18381289 18623064 19187765
CEP126 FAM118B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
JADE2 KAT7 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3D â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3C HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3A â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3C â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3A HIST2H3PS2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
H3F3B HIST2H3D â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
JADE1 KAT7 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
KAT7 MEAF6 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
ING5 KAT7 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
H3F3B MCM2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
HIST2H3D MCM2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
BRPF1 HIST2H3D â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
BRPF1 HIST1H3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
HIST3H3 KAT6A â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HIST1H3A KAT6A â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
ING5 MEAF6 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
BRD1 KAT7 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
MCM2 MCM4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 MCM4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM6 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 MCM2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
CDK2 MCM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 17081983 17303408 19793801 15279786 7575488 11454864 16517729 20068231 17116885 17582221 16519687 10748114 18669648 18590585 12714602 17660363 19651622 17296725 17924679 17102137 16964243
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CDK2 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7575488 18590585 17296725 17303408 16899510 17102137 17116885 19793801 17582221 16446360 17570479 26549452 17660363 15279786
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
KAT7 MCM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278932 16713569 16428461
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
MCM4 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16902406 12694531 22939629 12614612 25963833 10567526 22540012 8798650 14681455 22863883 33961781 27173435 16899510 17296731 26344197
MCM6 MCM2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16189514 25416956 12694531 20211142 14681455 12207017 12614612 26496610 25963833 30100344 22939629 17296731 26167883 10567526 22540012 22863883 33961781 27173435 16899510 26344197
MCM4 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM6 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16902406 12694531 12364596 12614612 22939629 26496610 8798650 12207017 22863883 27173435 17296731 26344197
MCM4 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829